公开(公告)号：DE50213015D1

公开(公告)日：2008-12-24

申请号：DE50213015

申请日：2002-10-17

Applicant: BASF SE

Inventor： MATUSCHEK MARKUS ,  STUERMER RAINER ,  HAUER BERNHARD ,  KLEBE GERHARD ,  BOCOLA MARCO

IPC: C12N15/09 ,  C12N15/55 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/20 ,  C12P41/00

Abstract: The invention relates to a lipase variant which can be prepared by carrying out, on the amino acid sequence of a starting lipase selected from the lipase homologous family I.1 or I.2, at least one amino acid substitution in those positions which correspond to the positions 17, 29, 30, 52, 86, 117, 122, 160, 163, 167, 265, 266, 286, 289 in the prototype lipase sequence SEQ ID NO: 1.

公开(公告)号：AT396276T

公开(公告)日：2008-06-15

申请号：AT06000642

申请日：2000-10-26

Applicant: BASF SE

Inventor： SCHMID ANDREAS ,  WITHOLT BERNARD ,  HAUER BERNHARD ,  BUEHLER BRUNO

IPC: C12N15/09 ,  C12Q1/26 ,  C12N1/21 ,  C12P7/24 ,  C12P7/40 ,  C12R1/19 ,  C12R1/38

Abstract: Production of aromatic aldehyde or carboxylic acid (I) by culturing a microorganism that expresses xylene mono-oxygenase (XMO) or alkane mono-oxygenase (AMO) in a medium containing an aromatic substrate (II). Production of aromatic aldehyde or carboxylic acid of formula (I) by culturing a microorganism that expresses xylene mono-oxygenase (XMO) or alkane mono-oxygenase (AMO) in a medium containing an aromatic substrate of formula (II). [Image] Ar : monocyclic aromatic ring, optionally with one or more substituents; R 1>formyl or carboxy; n : 0-15; R 2>vinyl or (CH 2) m-R 3>, also where R 1>= carboxy, R 2>may be (CH 2) n-CHO; m : n+1; and R 3>hydrogen or hydroxy. Independent claims are also included for the following: (a) recombinant microorganism harboring an expression vector that contains, under control of the alk-regulatory system of Pseudomonas oleovoransGpol, the XMO-encoding genes xylM and xylA, or the AMO-encoding genes alkB, alkG and alkT; and (b) expression construct containing the genes specified in (a), operably linked to the alk-regulatory system.

公开(公告)号：ES2552768T3

公开(公告)日：2015-12-02

申请号：ES10720575

申请日：2010-05-05

Applicant: BASF SE

Inventor： STÜRMER RAINER ,  DREW DEJANA ,  HAUER BERNHARD ,  DÄUWEL JÜRGEN ,  MEISENBURG UWE

IPC: C12P7/62 ,  C12P13/02

Abstract: Procedimiento de preparación de ésteres de ácido (met)acrílico que contienen grupos uretano (U) mediante reacción de un alcohol que contiene grupos uretano (A) con un éster de ácido (met)acrílico de un alcohol saturado (G) en presencia de al menos un inhibidor de la polimerización (P) con una enzima (E) como catalizador en un reactor, caracterizado porque a) el alcohol saturado liberado y el agente de arrastre dado el caso usado con el éster de ácido (met)acrílico (G) correspondiente en exceso forman un azeótropo, el azeótropo se elimina por destilación a presión reducida y b) al menos una corriente parcial procedente del fondo del reactor se hace circular a través de la cabeza de la columna de destilación.

公开(公告)号：CY1107811T1

公开(公告)日：2013-06-19

申请号：CY071101499

申请日：2007-11-22

Applicant: BASF SE

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN

IPC: C12M1/40 ,  C12N15/53 ,  C12N1/21 ,  C12N9/02 ,  C12N15/09 ,  C12N15/70 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/42 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/11 ,  C12R1/19

Abstract: ΗπαρούσαεφεύρεσηαφοράτροποποιημένεςμονοοξυγενάσεςκυτοχρώματοςΡ450 μετροποποιημένοπροφίλυποστρώματος, ακολουθίεςνουκλεϊνικούοξέοςπουκωδικεύουνκατασκευάσματαέκφρασηςκαιφορείς, ανασυνδυασμένουςμικροοργανισμούς, οιοποίοιπεριέχουντουςφορείςαυτούςκαθώςκαιμεθόδουςγιατηνμικροβιολογικήπαρασκευήακροτελικάή υπο-ακροτελικάυδροξυλιωμένωναλειφατικώνκαρβονικώνοξέων.

公开(公告)号：AT551424T

公开(公告)日：2012-04-15

申请号：AT01987798

申请日：2001-10-16

Applicant: BASF SE

Inventor： HAUER BERNHARD ,  SCHMID ROLF ,  MERKL RAINER ,  BLASCO FRANCESCA

IPC: C12N15/09 ,  C12N15/53 ,  C12M1/40 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/02 ,  C12P1/04 ,  C12P7/00 ,  C12R1/01

Abstract: The invention relates to novel cytochrome P450 monooxygenases from thermophilic bacteria, in particular the genus Thermus sp., to nucleotide sequences encoding them, to the recombinant production of these monooxygenases and to their use for the microbiological oxidation of organic compounds.

公开(公告)号：AT530660T

公开(公告)日：2011-11-15

申请号：AT06792615

申请日：2006-07-31

Applicant: BASF SE

Inventor： HAERING DIETMAR ,  MEISENBURG UWE ,  HAUER BERNHARD ,  DIETSCHE FRANK

IPC: C12P7/62

Abstract: The present invention relates to a process for preparing (meth)acrylic esters of alcohols having C—C triple bonds, to processes for their preparation, and to their use.

公开(公告)号：DK1969132T3

公开(公告)日：2011-06-06

申请号：DK06830606

申请日：2006-12-13

Applicant: BASF SE

Inventor： STUERMER RAINER ,  KESSELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL ,  SCHROEDER HARTWIG

IPC: C12P17/16 ,  C07D333/16 ,  C07D333/20

公开(公告)号：DE502006009034D1

公开(公告)日：2011-04-14

申请号：DE502006009034

申请日：2006-12-13

Applicant: BASF SE

Inventor： STUERMER RAINER ,  KESSELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL ,  SCHROEDER HARTWIG

IPC: C12P17/16 ,  C07D333/16 ,  C07D333/20

公开(公告)号：SI1984515T1

公开(公告)日：2010-12-31

申请号：SI200730390

申请日：2007-01-31

Applicant: BASF SE

Inventor： HAUER BERNHARD ,  STURMER RAINER ,  NESTL BETTINA M ,  KROUTIL WOLFGANG ,  FABER KURT

IPC: C12P7/24 ,  C12P41/00

公开(公告)号：PT1670779E

公开(公告)日：2010-12-16

申请号：PT04765718

申请日：2004-09-30

Applicant: BASF SE

Inventor： FRIEDRICH THOMAS ,  KESSELER MARIA ,  HAUER BERNHARD ,  STUERMER RAINER ,  BREUER MICHAEL

IPC: C07D333/16 ,  C07D333/20 ,  C12N9/04 ,  C12N15/53 ,  C12N15/63 ,  C12P7/04