BIOCHEMICAL REACTION APPARATUS, SUBSTRATE FOR BIOCHEMICAL REACTION, MANUFACTURING METHOD OF SUBSTRATE FOR HYBRIDIZATION AND HYBRIDIZATION METHOD

    公开(公告)号:JP2005030783A

    公开(公告)日:2005-02-03

    申请号:JP2003193064

    申请日:2003-07-07

    Applicant: SONY CORP

    Abstract: PROBLEM TO BE SOLVED: To provide a biochemical reaction apparatus capable of performing a biochemical reaction by using a substrate, the substrate for the biochemical reaction such as a DNA (deoxyribonucleic acid) chip, a hybridization method of hybridizing a nucleotide chain, and a biochemical reaction apparatus capable of performing hybridization at a high speed relative to a substrate manufacturing method for the hybridization wherein the nucleotide chain for a probe is immobilized. SOLUTION: As for the substrate 1 for bioassay, the main surface similar to an optical disk such as a CD has an annular flat shape. The substrate 1 is driven rotatively around a center hole 2, and the substrate 1 has the surface 1a on which a plurality of wells 8 are formed, which are fields for a hybridization reaction between a probe DNA (a nucleotide chain for detection) and a sample DNA (a target nucleotide chain). A transparent electrode film 4 is formed on the lower layer of the wells 8 on the substrate 1. At the hybridization time, an external electrode 18 is brought close from the upper surface 1a side of the substrate 1, and an alternating-current power is applied between the transparent electrode film 4 and the external electrode 18, to thereby give an alternating-current field in the vertical direction to the substrate 1. COPYRIGHT: (C)2005,JPO&NCIPI

    OPTOELECTRIC INTEGRATED CIRCUIT DEVICE

    公开(公告)号:JP2001237411A

    公开(公告)日:2001-08-31

    申请号:JP2000048965

    申请日:2000-02-21

    Applicant: SONY CORP

    Abstract: PROBLEM TO BE SOLVED: To provide an optoelectric integrated circuit device which can prevent the clock skew, even the level of integration is increased, and is capable of processing signals at high speeds. SOLUTION: An electronic element layer 4, provided with electronic elements D, an electronic wiring layer 2 provided with electronic wirings W, a light guide surface 3, a plurality of light-emitting elements L1 and so on and a plurality of photodetecting elements P1 and so on are disposed on the same substrate 1, the electronic elements D and the electronic wirings W constitute circuit blocks B1 and so on the light-emitting elements are connected to an output part, and the photodetecting elements are connected to an input part. The light emitting elements and the photodetecting elements are coupled on the same light guide surface, the photodetecting elements couple signal light pulses intensity-modulated by signals and clock light pulses intensity-modulated by a clock frequency with the same light guide surface, and the photodetecting elements receive the clock light pulse to control the clock frequency and phase of the circuit blocks.

    SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE

    公开(公告)号:JPH04340735A

    公开(公告)日:1992-11-27

    申请号:JP11271191

    申请日:1991-05-17

    Applicant: SONY CORP

    Abstract: PURPOSE:To easily check electric continuity of a semiconductor integrated circuit device. CONSTITUTION:From above the peripheral part or the peripheral edge part of a package 3 of a semiconductor integrated circuit device 1, contact holes 4 are formed on the surfaces of inner leads 5 corresponding with the respective outer leads 2. From the upper surface of the semiconductor integrated circuit device 1, electric continuity of leads can be easily checked.

    SEMICONDUCTOR DEVICE
    35.
    发明专利

    公开(公告)号:JPS60229386A

    公开(公告)日:1985-11-14

    申请号:JP8486884

    申请日:1984-04-26

    Applicant: SONY CORP

    Abstract: PURPOSE:To obtain a semiconductor laser diode having stable characteristics by forming a non-current region to a semiconductor by implanting at least one kind of ions of He, Be, Li and B. CONSTITUTION:An N type first clad layer 2, a P type or N type active layer 3, a P type clad layer 4 and a P type low resistivity cap layer 5 are shaped on an N type base body 1 through epitaxial growth in succession. A mask 7 is formed on the cap layer 5, and boron B is implanted in depth intruding to the thickness of one part of the second clad layer 4 from the upper section of the cap layer 5 to shape a non-current injecting region 21 having high resistance. The mask is removed, and electrodes 7, 8 are applied, thus obtaining a semiconductor laser diode having stable characteristics. He, Be, Li, etc. can be used besides B as implanting ions.

    SEMICONDUCTOR DEVICE
    37.
    发明专利

    公开(公告)号:JPS5563869A

    公开(公告)日:1980-05-14

    申请号:JP13803978

    申请日:1978-11-09

    Applicant: SONY CORP

    Abstract: PURPOSE:To raise the controllability and reproducibility of the lifetime of carriers and facilitate the control of temperature dependence, by providing iron, gold and/or platinum in a semiconductor layer to control the lifetime of carriers. CONSTITUTION:Iron ions are implanted at the rate of 1X10 cm into a GTO thyristor from its reverse side. The thyristor is then annealed at a temperature of 1000 deg.C under an atmosphere of nitrogen for 1 hour. A gold film is evaporated at a thickness of 600Angstrom on the reverse side and diffused at a temperature of 890 deg.C. The recovery time Trr of GCS with gold and iron diffused is almost constant independently of the diffusion time of the gold. The lifetime tau is affected by the gold in the main at low temperature but by the iron in the main at high temperature. Diffusing both iron and gold in a semiconductor device is preferable to flatten its forward voltage VF. Since plural kinds of killers are used, the control of the lifetime is facilitated.

    Visualization method and visualization apparatus related to biological material information, and information storage medium
    39.
    发明专利
    Visualization method and visualization apparatus related to biological material information, and information storage medium 有权
    与生物材料信息和信息存储介质相关的可视化方法和可视化装置

    公开(公告)号:JP2010262667A

    公开(公告)日:2010-11-18

    申请号:JP2010153946

    申请日:2010-07-06

    Abstract: PROBLEM TO BE SOLVED: To facilitate understanding of interaction mechanisms and metabolic systems of biological materials. SOLUTION: In the method for visualizing information on biological materials such as genes or protein by automatically displaying the information on a computer display screen by use of a computer system, biological materials belonging to the same class and interaction relations among the biological materials are displayed on the same layer on the computer display screen. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 要解决的问题:促进对生物材料的相互作用机制和代谢系统的理解。 解决方案:在通过使用计算机系统在计算机显示屏幕上自动显示信息的基因或蛋白质等生物材料信息的可视化方法中,生物材料属于相同类别的生物材料和生物材料之间的相互作用关系 显示在计算机显示屏上的同一层上。 版权所有(C)2011,JPO&INPIT

    Method for determining nucleic acid molecule base sequence and apparatus for determining the same
    40.
    发明专利
    Method for determining nucleic acid molecule base sequence and apparatus for determining the same 有权
    用于确定核酸分子基因序列的方法和用于测定其的装置

    公开(公告)号:JP2006094707A

    公开(公告)日:2006-04-13

    申请号:JP2004281000

    申请日:2004-09-28

    CPC classification number: C12Q1/6872 C12Q2565/607 C12Q2537/149 C12Q2521/319

    Abstract: PROBLEM TO BE SOLVED: To accurately and rapidly determine a base sequence of a nucleic acid molecule by measuring mass change of the nucleic acid molecule before or after cleavage treatment. SOLUTION: The prevent invention provides a method for determining a base sequence comprising at least carrying out a first step for cleaving a target nucleic molecule N while controlling a cleaving part (e.g. decomposition part by enzyme), a second step for measuring mass change of mass difference information of a nucleic acid molecule (N 1 and N 2 ) after the first step to the mass of the target nucleic acid molecule N and a third step for obtaining base information of cleaved nucleic acid molecules (n 1 and n 2 ) based on the measured data. The present invention further provides an apparatus, etc., suitable for the method. COPYRIGHT: (C)2006,JPO&NCIPI

    Abstract translation: 待解决的问题:通过测量裂解处理之前或之后的核酸分子的质量变化,准确且快速地确定核酸分子的碱基序列。 解决方案:本发明提供了一种确定碱基序列的方法,包括至少在控制切割部分(例如酶的分解部分)的同时进行用于切割靶核酸分子N的第一步骤,第二步是测量质量 将第一步后的核酸分子(N 1 和N 2 )的质量差异信息改变为靶核酸分子N的质量,第三步 基于测量数据获得切割的核酸分子的基本信息(n 1 和n 2 )。 本发明还提供一种适用于该方法的装置等。 版权所有(C)2006,JPO&NCIPI

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