Abstract:
PURPOSE: A method for detecting a marker contained in a biological sample is provided to diagnose and treat obesity or obesity-associated diseases. CONSTITUTION: A method for detecting a marker contained in a biological sample for diagnosing obesity comprises a step of detecting the concentration of arginine, tyrosine, pipecolic acid, benzoic acid, pantothenic acid, uric acid, phenyl acetamide, serotonin, L-carnitine, decanoyl carnitine, myristoyl carnitine, hexadekenoyl carnitine, linoleyl carnitien, vacenyl carnitine, stearoyl carnitine, lysoPC(C14:0), lysoPC(C15:0), lysoPC(C16:0), lysoPC(C16:1), lysoPC(C17:0), lysoPC(C17:1), lysoPC(C18:0), lysoPC(C18:1), lysoPC(C18:2), lysoPC(C18:3), lysoPC(C19:0), lysoPC(C20:1), lysoPC(C20:4), lysoPC(C20:5), lysoPE(C18:2), lysoPE(C20:4) or PCs marker in blood or glucose, glycerol, tyrosine, valine, 7-ketodeoxy cholic acid, and betain, L-carnitine, plamitic acid, linoleic acid, oleic acid, stearic acid, lysoPC(C14:0), lysoPC(C16:0), lysoPC(C16:1), lysoPC(C18:0), lysoPC(C18:3), lysoPC(C20:4), lysoPC(C22:6), or PCs in liver tissue.
Abstract:
PURPOSE: A composition containing Chelidonium majus var asiaticum extract is provided to activate AMPK(5'AMP-activated protein kinase) and to ensure antiobesity. CONSTITUTION: A composition for preventing and treating obesity contains 0.1-99.9 wt% of Chelidonium majus var asiaticum extract as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The food composition for preventing and treating obesity contains the extract as an active ingredient. The extract is a hot water extract or ethanol extract. The composition is manufactured in the form of beverage, gum, tea, vitamin complex, pill, powder, granule, tablet, or capsule.
Abstract translation:目的:提供含有Chelidonium majus var asiaticum提取物的组合物以激活AMPK(5'AMP-活化的蛋白激酶)并确保抗肥胖。 构成:用于预防和治疗肥胖症的组合物含有0.1-99.9wt%的Chelidonium majus var asiaticum提取物作为活性成分。 该组合物是药物组合物或食品添加剂组合物。 用于预防和治疗肥胖症的食物组合物含有提取物作为活性成分。 提取物是热水提取物或乙醇提取物。 该组合物以饮料,口香糖,茶叶,维生素复合物,丸剂,粉末,颗粒,片剂或胶囊的形式制成。
Abstract:
PURPOSE: A composition containing 3-methyladenine is provided to decompose neutral lipid into glycerol and free fatty acid and to prevent or treat obesity, diabetes, and hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity contains 3-methyladenien as an active ingredient. 3-methyladenine decomposes neutral lipid into glycerol and free fatty acid. A food composition for preventing or treating obesity contains 3-methyladenine as an active ingredient. The composition is used for preventing or treating obesity-associated metabolic diseases including diabetes, arteriosclerosis, metabolic diseases, and hyperlipidemia. The pharmaceutical composition is manufactured in the form of a liquid formulation or parenteral formulation.
Abstract:
PURPOSE: A composition containing genistein or pharmacologically acceptable salt thereof is provided to suppress fractalkine expression and vascular inflammation. CONSTITUTION: A composition for treating vasculitis caused by fractalkine expression contains 1-10 wt% of genistein or pharmacologically acceptable salt thereof as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The composition also contains NF-kappaB inhibitor and p38 inhibitor or PI3'-K inhibitor in a weight ratio of 1:10-10:1.
Abstract:
PURPOSE: A composition containing euphobiasteroid is provided to effectively suppress the differentiation of induced adipocytes and to prevent or treat obesity. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity contains euphobiasteroid as an active ingredient. A food composition for preventing or treating obesity contains euphobiasteroid as an active ingredient. Euphobiasteroid is isolated from Euphorbiae Lathyridis semen using a solvent. The solvent is water, anhydrous or hydrous low alcohol of 1-4 carbon atoms(methanol, ethano, propanol, butanol), mixture solvent of low alcohol and water, acetone, ethyl acetate, chloroform, or 1,3-butylene glycol.
Abstract:
본 발명은 혈류 개선용 조성물, 이의 제조 방법 및 이를 포함하는 건강기능식품에 관한 것으로, 본 발명의 혈류 개선용 조성물은 산약을 젖산균으로 발효시킨 발효물로부터 분리된 분자량 100,000 dalton이하의 분획물을 포함한다. 본 발명의 조성물은 콜레스테롤 합성 저해 능력 및 담즙산 결합 능력이 우수하여 혈류를 개선시킨다.