비만여부를 진단하기 위한 생물학적 시료내 함유된 마커의 검출방법 및 이를 이용한 스크리닝 방법
    41.
    发明公开
    비만여부를 진단하기 위한 생물학적 시료내 함유된 마커의 검출방법 및 이를 이용한 스크리닝 방법 有权
    用于确定生物量的生物样品中标记的检测方法及其使用的筛选方法

    公开(公告)号:KR1020120017912A

    公开(公告)日:2012-02-29

    申请号:KR1020100080863

    申请日:2010-08-20

    Abstract: PURPOSE: A method for detecting a marker contained in a biological sample is provided to diagnose and treat obesity or obesity-associated diseases. CONSTITUTION: A method for detecting a marker contained in a biological sample for diagnosing obesity comprises a step of detecting the concentration of arginine, tyrosine, pipecolic acid, benzoic acid, pantothenic acid, uric acid, phenyl acetamide, serotonin, L-carnitine, decanoyl carnitine, myristoyl carnitine, hexadekenoyl carnitine, linoleyl carnitien, vacenyl carnitine, stearoyl carnitine, lysoPC(C14:0), lysoPC(C15:0), lysoPC(C16:0), lysoPC(C16:1), lysoPC(C17:0), lysoPC(C17:1), lysoPC(C18:0), lysoPC(C18:1), lysoPC(C18:2), lysoPC(C18:3), lysoPC(C19:0), lysoPC(C20:1), lysoPC(C20:4), lysoPC(C20:5), lysoPE(C18:2), lysoPE(C20:4) or PCs marker in blood or glucose, glycerol, tyrosine, valine, 7-ketodeoxy cholic acid, and betain, L-carnitine, plamitic acid, linoleic acid, oleic acid, stearic acid, lysoPC(C14:0), lysoPC(C16:0), lysoPC(C16:1), lysoPC(C18:0), lysoPC(C18:3), lysoPC(C20:4), lysoPC(C22:6), or PCs in liver tissue.

    Abstract translation: 目的:提供一种用于检测生物样品中包含的标记物的方法,用于诊断和治疗肥胖或肥胖相关疾病。 构成:用于检测用于诊断肥胖的生物样品中所含的标记物的方法包括检测精氨酸,酪氨酸,哌可酸,苯甲酸,泛酸,尿酸,苯乙酰胺,5-羟色胺,L-肉毒碱,癸酰基 肉毒碱,肉豆蔻肉碱,六酰基肉碱,亚油酰肉碱,肉桂碱肉碱,硬脂酰肉碱,溶血糖(C14:0),溶血卵磷脂(C15:0),溶血卵磷脂(C16:0),溶血卵磷脂(C16: ),lysoPC(C17:1),lysoPC(C18:0),lysoPC(C18:1),lysoPC(C18:1),lysoPC(C18:2),lysoPC(C18:3) ,血液或葡萄糖,甘油,酪氨酸,缬氨酸,7-酮基脱氧胆酸和甜菜碱中的溶血卵磷脂(C20:4),溶血卵磷脂(C20:5),溶血蛋白(C18:2),溶血蛋白(C20:4) ,L-carnitine,plamitic acid,亚油酸,油酸,硬脂酸,lysoPC(C14:0),lysoPC(C16:0),lysoPC(C16:1),lysoPC(C18:0),lysoPC(C18:3 ),溶血卵磷脂(C20:4),溶血卵磷脂(C22:6)或肝组织中的PC。

    백굴채 추출물을 유효성분으로 함유하는 비만예방 및 치료용 조성물
    42.
    发明公开
    백굴채 추출물을 유효성분으로 함유하는 비만예방 및 치료용 조성물 无效
    预防和治疗包含CHARIDONIUM MAJUS VAR ASIATICUM萃取物的成分的组合物

    公开(公告)号:KR1020120003778A

    公开(公告)日:2012-01-11

    申请号:KR1020100064563

    申请日:2010-07-05

    CPC classification number: A61K36/66 A61K2236/33 Y10S514/909

    Abstract: PURPOSE: A composition containing Chelidonium majus var asiaticum extract is provided to activate AMPK(5'AMP-activated protein kinase) and to ensure antiobesity. CONSTITUTION: A composition for preventing and treating obesity contains 0.1-99.9 wt% of Chelidonium majus var asiaticum extract as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The food composition for preventing and treating obesity contains the extract as an active ingredient. The extract is a hot water extract or ethanol extract. The composition is manufactured in the form of beverage, gum, tea, vitamin complex, pill, powder, granule, tablet, or capsule.

    Abstract translation: 目的:提供含有Chelidonium majus var asiaticum提取物的组合物以激活AMPK(5'AMP-活化的蛋白激酶)并确保抗肥胖。 构成:用于预防和治疗肥胖症的组合物含有0.1-99.9wt%的Chelidonium majus var asiaticum提取物作为活性成分。 该组合物是药物组合物或食品添加剂组合物。 用于预防和治疗肥胖症的食物组合物含有提取物作为活性成分。 提取物是热水提取物或乙醇提取物。 该组合物以饮料,口香糖,茶叶,维生素复合物,丸剂,粉末,颗粒,片剂或胶囊的形式制成。

    3-메틸아데닌을 유효성분으로 함유하는 비만 예방, 치료 또는 개선용 조성물
    43.
    发明公开
    3-메틸아데닌을 유효성분으로 함유하는 비만 예방, 치료 또는 개선용 조성물 无效
    含有3-甲基腺嘌呤的组合物用于预防,治疗或改善肥胖

    公开(公告)号:KR1020110136215A

    公开(公告)日:2011-12-21

    申请号:KR1020100056077

    申请日:2010-06-14

    Abstract: PURPOSE: A composition containing 3-methyladenine is provided to decompose neutral lipid into glycerol and free fatty acid and to prevent or treat obesity, diabetes, and hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity contains 3-methyladenien as an active ingredient. 3-methyladenine decomposes neutral lipid into glycerol and free fatty acid. A food composition for preventing or treating obesity contains 3-methyladenine as an active ingredient. The composition is used for preventing or treating obesity-associated metabolic diseases including diabetes, arteriosclerosis, metabolic diseases, and hyperlipidemia. The pharmaceutical composition is manufactured in the form of a liquid formulation or parenteral formulation.

    Abstract translation: 目的:提供含有3-甲基腺嘌呤的组合物,以将中性脂质分解为甘油和游离脂肪酸,并预防或治疗肥胖,糖尿病和高脂血症。 构成:用于预防或治疗肥胖症的药物组合物含有3-甲基腺嘌呤作为活性成分。 3-甲基腺嘌呤将中性脂质分解成甘油和游离脂肪酸。 用于预防或治疗肥胖症的食物组合物含有3-甲基腺嘌呤作为活性成分。 该组合物用于预防或治疗肥胖相关代谢疾病,包括糖尿病,动脉硬化,代谢疾病和高脂血症。 药物组合物以液体制剂或肠胃外制剂的形式制备。

    프랙탈카인 발현에 의해 야기되는 혈관염 치료용 조성물
    44.
    发明公开
    프랙탈카인 발현에 의해 야기되는 혈관염 치료용 조성물 有权
    治疗组合物对血管紧张素转化酶诱导的血管炎的影响

    公开(公告)号:KR1020110135706A

    公开(公告)日:2011-12-19

    申请号:KR1020100055579

    申请日:2010-06-11

    Abstract: PURPOSE: A composition containing genistein or pharmacologically acceptable salt thereof is provided to suppress fractalkine expression and vascular inflammation. CONSTITUTION: A composition for treating vasculitis caused by fractalkine expression contains 1-10 wt% of genistein or pharmacologically acceptable salt thereof as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The composition also contains NF-kappaB inhibitor and p38 inhibitor or PI3'-K inhibitor in a weight ratio of 1:10-10:1.

    Abstract translation: 目的:提供含有染料木素或其药理学上可接受的盐的组合物以抑制分裂素表达和血管炎症。 构成:用于治疗由fractalkine表达引起的血管炎的组合物含有1-10重量%的染料木黄酮或其药理学上可接受的盐作为活性成分。 该组合物是药物组合物或食品添加剂组合物。 组合物还含有重量比为1:10-10:1的NF-κB抑制剂和p38抑制剂或PI3'-K抑制剂。

    유포비아스테로이드를 유효성분으로 함유하는 비만 예방, 치료 또는 개선용 조성물
    45.
    发明授权
    유포비아스테로이드를 유효성분으로 함유하는 비만 예방, 치료 또는 개선용 조성물 失效
    含有类胡萝卜素的组合物用于预防,治疗或改善肥胖

    公开(公告)号:KR101089314B1

    公开(公告)日:2011-12-02

    申请号:KR1020100053436

    申请日:2010-06-07

    Abstract: PURPOSE: A composition containing euphobiasteroid is provided to effectively suppress the differentiation of induced adipocytes and to prevent or treat obesity. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity contains euphobiasteroid as an active ingredient. A food composition for preventing or treating obesity contains euphobiasteroid as an active ingredient. Euphobiasteroid is isolated from Euphorbiae Lathyridis semen using a solvent. The solvent is water, anhydrous or hydrous low alcohol of 1-4 carbon atoms(methanol, ethano, propanol, butanol), mixture solvent of low alcohol and water, acetone, ethyl acetate, chloroform, or 1,3-butylene glycol.

    Abstract translation: 目的:提供含有对虾脂肪的组合物,以有效抑制诱导的脂肪细胞的分化和预防或治疗肥胖。 构成:用于预防或治疗肥胖症的药物组合物含有作为活性成分的兴奋石甾醇。 用于预防或治疗肥胖症的食物组合物含有作为活性成分的兴奋石甾醇。 使用溶剂从Euphorbiae Lathyridis精液中分离出Euphobiasteroid。 溶剂为1-4碳原子的水,无水或含水低级醇(甲醇,乙醇,丙醇,丁醇),低级醇和水的混合溶剂,丙酮,乙酸乙酯,氯仿或1,3-丁二醇。

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