公开(公告)号：KR1020040092186A

公开(公告)日：2004-11-03

申请号：KR1020030026416

申请日：2003-04-25

Applicant: 한국화학연구원

Inventor： 전동주 ,  김형래 ,  송종환 ,  박관용 ,  정순민 ,  황인택

IPC: A01N43/90

Abstract: PURPOSE: Provided are 9-(5-isoxazolemethoxyphenyl)imino-8-thia-1,6-diazabicyclo(4.3.0)nonan-7-one derivatives which have herbicidal activity and a herbicidal composition containing the same as active ingredient. The derivatives have high stability to rice and excellent herbicidal effect. CONSTITUTION: 9-(5-isoxazolemethoxyphenyl)imino-8-thia-1,6-diazabicyclo(4.3.0)nonan-7-one derivative is represented by the formula(1), wherein R is C1-C5 alkyl group, phenyl group or substituted phenyl group in which the substituted phenyl group has a substituent selected from C1-C3 alkoxy group, halogen atom, cyano group and carboxylic acid ester group. The herbicidal composition is characterized by containing the 9-(5-isoxazolemethoxyphenyl)imino-8-thia-1,6-diazabicyclo(4.3.0)nonan-7-one derivative as active ingredient.

Abstract translation: 目的：提供具有除草活性的9-（5-异恶唑甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环（4.3.0）壬-7-酮衍生物和含有与活性成分相同的除草组合物。 该衍生物对水稻的稳定性高，除草效果好。 构型：9-（5-异恶唑甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环（4.3.0）壬-7-酮衍生物由式（1）表示，其中R是C1-C5烷基，苯基 基团或取代的苯基，其中取代的苯基具有选自C 1 -C 3烷氧基，卤素原子，氰基和羧酸酯基的取代基。 除草组合物的特征在于含有9-（5-异恶唑甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环（4.3.0）壬-7-酮衍生物作为活性成分。

公开(公告)号：KR1020040086696A

公开(公告)日：2004-10-12

申请号：KR1020030021052

申请日：2003-04-03

Applicant: 한국화학연구원

Inventor： 전동주 ,  김형래 ,  송종환 ,  장규환 ,  황인택

IPC: C07D405/12

Abstract: PURPOSE: Herbicidal2-(5-oxiranylmethoxyphenyl)-4,5,6,7-tetrahydro-2H-indazole derivatives are provided, which compounds have improved herbicidal effects and selectivity, so that the compounds can selectively kill weeds. CONSTITUTION: The herbicidal2-(5-oxiranylmethoxyphenyl)- 4,5,6,7-tetrahydro-2H-indazole derivatives represented by formula (1) are provided, wherein R1, R2 and R3 are independently hydrogen, C1-C5 alkyl, phenyl or substituted phenyl with 1 to 3 of halogen atoms. The method for preparing the herbicidal2-(5-oxiranylmethoxyphenyl)- 4,5,6,7-tetrahydro-2H-indazole derivatives of formula (1) comprises the steps of: reacting a compound of formula (2) with allyl halide in the presence of base to prepare a compound of formula (3); and introducing epoxy group into a double bond of the compound of formula (3), wherein X is halogen.

Abstract translation: 目的：提供除草剂2-（5-环氧乙烷基甲氧基苯基）-4,5,6,7-四氢-2H-吲唑衍生物，该化合物具有改善的除草效果和选择性，使得化合物可以选择性地杀死杂草。 构成：提供由式（1）表示的除草2-（5-环氧乙烷基甲氧基苯基）-4,5,6,7-四氢-2H-吲唑衍生物，其中R 1，R 2和R 3独立地是氢，C 1 -C 5烷基，苯基 或具有1至3个卤素原子的取代的苯基。 制备式（1）的除草-2-（5-环氧乙烷基甲氧基苯基）-4,5,6,7-四氢-2H-吲唑衍生物的方法包括以下步骤：使式（2）的化合物与烯丙基卤在 碱的存在以制备式（3）的化合物; 并将环氧基引入到式（3）化合物的双键中，其中X是卤素。

公开(公告)号：KR1020040017892A

公开(公告)日：2004-03-02

申请号：KR1020020049819

申请日：2002-08-22

Applicant: 한국화학연구원

Inventor： 유응걸 ,  전동주 ,  김형래 ,  송종환 ,  박관용 ,  하진열 ,  김진석

IPC: C07D495/04

Abstract: PURPOSE: Provided are derivatives of 9-(5-isoxazolinemethoxyphenyl)imino-8-thia-1.6-diazabicylco£4.3.0|nonane-7-one, represented by the formula(1) and herbicides containing them as active ingredients and having excellent herbicidal activity and selectivity when applied to a rice paddy. CONSTITUTION: Derivatives are represented by the formula(1), wherein R is C1-C6 alkyl, phenyl or substituted phenyl, wherein substituents are 1-3 of halogen atom, C1-C3 alkyl, C1-C3 alkoxy, C1-C3 haloalkyl, cyano, nitro, carboxyl and esters of carboxy acid.

Abstract translation: 目的：提供由式（1）表示的9-（5-异恶唑啉甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环[4.3.0]壬烷-7-酮和含有它们作为活性成分并具有优异的除草剂的衍生物 施用于水稻时的除草活性和选择性。 构成：衍生物由式（1）表示，其中R是C1-C6烷基，苯基或取代的苯基，其中取代基是1-3的卤素原子，C1-C3烷基，C1-C3烷氧基，C1-C3卤代烷基， 氰基，硝基，羧基和羧酸的酯。

公开(公告)号：KR1020030095677A

公开(公告)日：2003-12-24

申请号：KR1020020033207

申请日：2002-06-14

Applicant: 한국화학연구원

Inventor： 유응걸 ,  전동주 ,  김형래 ,  송종환 ,  박관용

IPC: C07D231/54

Abstract: PURPOSE: A process for preparing 3-chloro-2- (4-chloro-2-fluoro-5-hydroxyphenyl)- 4,5,6,7-tetrahydro-2H-indazole is provided, thereby improving its preparation yield and converting by-products of the preparation into starting material. CONSTITUTION: A process for preparing 3-chloro-2- (4-chloro-2-fluoro-5-hydroxyphenyl)- 4,5,6,7-tetrahydro-2H-indazole of the formula 1 comprises the steps of: reacting 2- (2-fluoro-4-chloro-5-hydroxyphenyl)- 2,3a,4,5,6,7- hexahydroindazole-3-one of the formula 2 with phosgene; concentrating the phosgene reaction mixture under reduced pressure; dissolving the concentrate in an organic solvent; adding ammonia water or hydroxide solution to the organic solvent and filtering solids; and distilling the filtrated solution, wherein the organic solvent is ethylacetate; the addition of ammonia water or hydroxide solution is carried out at room temperature; the solids are mainly constituted of a compound of the formula 2, and the by-products of the reaction include a dimer represented by the formula 3a, 3b or 3c.

Abstract translation: 目的：提供3-氯-2-（4-氯-2-氟-5-羟基苯基）-4,5,6,7-四氢-2H-吲唑的制备方法，从而提高其制备产率，并通过 - 制备成原料的产品。 构成：式1的3-氯-2-（4-氯-2-氟-5-羟基苯基）-4,5,6,7-四氢-2H-吲唑的制备方法包括以下步骤：使2 - （2-氟-4-氯-5-羟基苯基）-2,3a，4,5,6,7-六氢吲唑-3-酮与光气; 在减压下浓缩光气反应混合物; 将浓缩物溶解在有机溶剂中; 向有机溶剂中加入氨水或氢氧化物溶液并过滤固体; 并蒸馏过滤的溶液，其中有机溶剂是乙酸乙酯; 在室温下加入氨水或氢氧化钠溶液; 固体主要由式2的化合物构成，反应的副产物包括由式3a，3b或3c表示的二聚体。

公开(公告)号：KR100339708B1

公开(公告)日：2002-06-05

申请号：KR1019990007558

申请日：1999-03-08

Applicant: 한국화학연구원

Inventor： 유응걸 ,  송종환 ,  김형래 ,  전동주 ,  정정애 ,  김경만 ,  김태준

IPC: C07D413/12

Abstract: 본발명은하기화학식 1로표시되는 N-(5-이속사졸리닐메틸옥시페닐)-디메틸말레이미드유도체및 그의제조방법에관한것으로, 본발명의화합물은벼에대한안전성이탁월하고피 (ECHOR), 올챙이고랑이 (SCPJU), 물달개비 (MOOVA), 너도방동산이 (CYPSE), 올미 (SAGPY) 등의논 잡초에대해고루우수한제초활성을보이므로이양벼및 직파벼조건에서논 잡초용제초제로유용하게사용될수 있다. 상기식에서 R 은명세서에기재된바와같다.

公开(公告)号：KR1020020019750A

公开(公告)日：2002-03-13

申请号：KR1020000052917

申请日：2000-09-07

Applicant: 한국화학연구원

Inventor： 유응걸 ,  김형래 ,  전동주 ,  송종환 ,  김경만 ,  이정노 ,  김형철 ,  홍경식

IPC: A01N43/80

CPC classification number: A01N43/80

Abstract: PURPOSE: Provided is 5-benzyloxymethyl-1,2-isoxazoline derivative which has an excellent herbicidal activity. Also, provided are its manufacturing method and herbicides containing the derivative as an active ingredient. CONSTITUTION: 5-benzyloxymethyl-1,2-isoxazoline derivative is represented by the formula(I), wherein X1, X2 and X3 individually represent hydrogen, methyl group, ethyl group, halogen group, methoxy group or nitro group (provided that it is an exception that X1, X2 and X3 are decimals all together); Y1, Y2 and Y3 are individually hydrogen or fluorine.

Abstract translation: 目的：提供具有优异除草活性的5-苄氧基甲基-1,2-异恶唑啉衍生物。 此外，其制造方法和含有该衍生物作为活性成分的除草剂。 构成：5-苄氧基甲基-1,2-异恶唑啉衍生物由式（I）表示，其中X1，X2和X3各自表示氢，甲基，乙基，卤素基，甲氧基或硝基（条件是它是 一个例外，X1，X2和X3都是小数） Y1，Y2和Y3分别为氢或氟。

公开(公告)号：KR100241260B1

公开(公告)日：2000-03-02

申请号：KR1019970065412

申请日：1997-12-02

Applicant: 한국화학연구원

Inventor： 유응걸 ,  김경만 ,  송종환 ,  황인택 ,  이수영 ,  김형래 ,  양순모

IPC: C07D215/32

Abstract: 본 발명은 제초활성을 갖는 화학식 1의 O-퀴놀리닐아미드옥심 유도체, 그의 제조방법 및 그를 포함하는 제초제 조성물에 관한 것이다.

(상기 식에서, R 은 명세서에서 정의한 바와 같다.)
상기 화학식 1의 O-퀴놀리닐아미드옥심 유도체 및 그를 유효성분으로 함유하는 조성물은 제초제 또는 식물생장 억제제로 유용하게 사용될 수 있다.

公开(公告)号：KR1019990047156A

公开(公告)日：1999-07-05

申请号：KR1019970065412

申请日：1997-12-02

Applicant: 한국화학연구원

Inventor： 유응걸 ,  김경만 ,  송종환 ,  황인택 ,  이수영 ,  김형래 ,  양순모

IPC: C07D215/32

Abstract: 본 발명은 제초활성을 갖는 화학식 1의 O-퀴놀리닐아미드옥심 유도체, 그의 제조방법 및 그를 포함하는 제초제 조성물에 관한 것이다.

(상기 식에서, R 은 명세서에서 정의한 바와 같다.)
상기 화학식 1의 O-퀴놀리닐아미드옥심 유도체 및 그를 유효성분으로 함유하는 조성물은 제초제 또는 식물생장 억제제로 유용하게 사용될 수 있다.

公开(公告)号：KR100088513B1

公开(公告)日：1995-08-30

申请号：KR1019920010223

申请日：1992-06-12

Applicant: 한국화학연구원

Inventor： 유응걸 ,  김형래 ,  송종환 ,  김재녕 ,  김경만 ,  김태준

IPC: C07D249/12

公开(公告)号：KR1019950004708B1

公开(公告)日：1995-05-04

申请号：KR1019920010697

申请日：1992-06-19

Applicant: 한국화학연구원

Inventor： 유응걸 ,  김경만 ,  김형래 ,  송종환 ,  신연호 ,  김태준

IPC: C07D311/04

Abstract: The new compound as 5-(2H-1-benzopyran-6-yl)-2-[1-(ethoxylimino) butyryl -3-hydroxy cyclohex-2-en-1-one (I) is prepared by (1) reacting 4-hydroxy benzaldehyde and 4-propazyl halide to get 4-propazyl 2H- 1- benzypyran-6- carboxaldehyde (II), (2) reacting (II) in alkali to get 4- (2H-1-benzopyran -6-y l0-3-buten-2-one (III), (3) reacting (III) with diethyl malonate to get 5-(2H-1-benzopyran-6-yl)- cyclohexan-1,3-dione (IV), (4) reacting (IV) with butyrate to get 2-butyryl-5-(2H-1-benzopyran-6-yl) -3-hydroxy cyclohex-2-en-1-one (V), reacting (V) with ethoxyl amine and sodium acetate to get (I). (I) as herbicide is useful for soybean, cotton, sugarbeet, sunflower, strawberry, wheat, corn and rice.

Abstract translation: 通过以下方法制备5-（2H-1-苯并吡喃-6-基）-2- [1-（乙氧基亚氨基）丁酰基-3-羟基环己-2-烯-1-酮（I）的新化合物：（1） 4-羟基苯甲醛和4-异辛酰卤，得到4-异辛酰基2H-1-苯并吡喃-6-甲醛（II），（2）使（II）在碱中反应，得到4-（2H-1-苯并吡喃-6-基） （III）与（III）与丙二酸二乙酯反应得到5-（2H-1-苯并吡喃-6-基） - 环己-1,3-二酮（IV）， （4）使（Ⅳ）与丁酸反应得到2-丁酰基-5-（2H-1-苯并吡喃-6-基）-3-羟基环己-2-烯-1-酮（Ⅴ），使（Ⅴ）与 乙醇胺和乙酸钠，得到（I）。（I）作为除草剂可用于大豆，棉花，甜菜，向日葵，草莓，小麦，玉米和大米。