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公开(公告)号：NZ503383A
公开(公告)日：2002-02-01
申请号：NZ50338397
申请日：1997-02-10
Applicant: ABBOTT LAB
Inventor： BOYD STEVEN A , SORENSEN BRYAN K , WINN MARTIN , JAE HWAN-SOO , VON GELDERN THOMAS W , HENRY KENNETH J , TASKER ANDREW S
IPC: A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/675 , A61P1/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P13/12 , A61P25/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14 , C07D453/02 , C07F9/572
Abstract: A method for contracting non-vascular smooth muscle in a guinea pig trachea in vitro is disclosed. The method comprises administering to the trachea a therapeutically effective amount of ethyl 2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-4,5-dihydro-3H-pyrrole-3-carboxlylate or a pharmaceutically acceptable salt thereof.
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公开(公告)号：AU6872401A
公开(公告)日：2002-01-14
申请号：AU6872401
申请日：2001-06-22
Applicant: ABBOTT LAB
Inventor： LINK JAMES T , SORENSEN BRYAN K
IPC: C07D295/04 , A61K31/198 , A61K31/397 , A61K31/4015 , A61K31/445 , A61K31/4453 , A61K31/495 , A61K31/5375 , A61K31/5377 , A61P29/00 , A61P37/06 , C07C323/62 , C07D205/04 , C07D207/26 , C07D207/27 , C07D211/60 , C07D211/62 , C07D295/096 , C07D295/13 , C07D295/18 , C07D295/185 , C07D401/12 , A61K31/16 , A61K31/33 , C07D295/08 , C07D295/12
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公开(公告)号：HU0002681A2
公开(公告)日：2001-08-28
申请号：HU0002681
申请日：1998-06-08
Applicant: ABBOTT LAB
Inventor： BOYD STEVEN A , HENRY KENNETH J , JAE HWAN-SOO , SORENSEN BRYAN K , TASKER ANDREW S , WINN MARTIN , VON GELDERN THOMAS W
IPC: C07D207/16 , C07D405/04
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公开(公告)号：CZ2000348A3
公开(公告)日：2001-03-14
申请号：CZ2000348
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , VON GELDERN THOMAS W , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: A61K31/40 , A61K31/445 , A61P7/02 , A61P9/00 , A61P37/00 , C07D207/16 , C07D403/04 , C07D405/04 , C07D405/14 , C07D417/14
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公开(公告)号：AU725122B2
公开(公告)日：2000-10-05
申请号：AU2034499
申请日：1999-03-10
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , VONGELDERN THOMAS W , KESTER JEFFREY A , SORENSEN BRYAN K
IPC: A61K31/40 , A61K31/402 , A61K31/4025 , A61K31/403 , A61K31/41 , A61K31/415 , A61K31/422 , A61K31/435 , A61K31/44 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/47 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/5377 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P29/00 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/14 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/10 , C07D405/14 , C07D413/04 , C07D419/04 , C07D471/04 , C07F9/572 , C07F9/59
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Patent Agency Ranking
公开(公告)号：ZA9806908B
公开(公告)日：1999-04-26
申请号：ZA9806908
申请日：1998-07-31
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: A61K20060101 , C07D20060101 , C07F20060101 , C07D , A61K , C07F
CPC classification number: Y02P20/55
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公开(公告)号：BR9707394A
公开(公告)日：1999-04-06
申请号：BR9707394
申请日：1997-02-10
Applicant: ABBOTT LAB
Inventor： TASKER ANDREW S , WINN MARTIN , GELDERN THOMAS W VON , SORENSEN BRYAN K , JAE HWAN-SOO , BOYD STEVEN A , HENRY KENNETH J
IPC: A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/675 , A61P1/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P13/12 , A61P25/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14 , C07D453/02 , C07F9/572
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公开(公告)号：CA2297894A1
公开(公告)日：1999-02-11
申请号：CA2297894
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： SZCZEPANKIEWICZ BRUCE G , SORENSEN BRYAN K , WINN MARTIN , HENRY KENNETH J , KESTER JEFFREY A , BOYD STEVEN A , HUTCHINS CHARLES W , WITTENBERGER STEVEN J , KING STEVEN A , GELDERN THOMAS W VON , TASKER ANDREW S , JAE HWAN-SOO , LIU GANG
IPC: C07D491/048 , A61K31/40 , A61K31/41 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/495 , A61K31/506 , A61K31/535 , A61K31/55 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/08 , A61P13/12 , A61P21/00 , A61P21/04 , A61P25/06 , A61P35/00 , A61P43/00 , C07D207/16 , C07D207/26 , C07D207/27 , C07D403/04 , C07D405/00 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D491/056
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof, is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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公开(公告)号：CA2517691A1
公开(公告)日：1996-02-29
申请号：CA2517691
申请日：1995-08-04
Applicant: ABBOTT LAB
Inventor： BOYD STEVEN A , TASKER ANDREW S , SORENSEN BRYAN K , VONGELDERN THOMAS W , KESTER JEFFREY A , JAE HWAN-SOO , WINN MARTIN , HUTCHINS CHARLES W
IPC: A61K31/40 , A61K31/402 , A61K31/4025 , A61K31/403 , A61K31/41 , A61K31/415 , A61K31/422 , A61K31/435 , A61K31/44 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/47 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/5377 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P29/00 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/14 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/10 , C07D405/14 , C07D413/04 , C07D419/04 , C07D471/04 , C07F9/572 , C07F9/59
Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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公开(公告)号：CA2195677A1
公开(公告)日：1996-02-29
申请号：CA2195677
申请日：1995-08-04
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , VONGELDERN THOMAS W , KESTER JEFFREY A , SORENSEN BRYAN K
IPC: A61K31/40 , A61K31/402 , A61K31/4025 , A61K31/403 , A61K31/41 , A61K31/415 , A61K31/422 , A61K31/435 , A61K31/44 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/47 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/5377 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P29/00 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/14 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/10 , C07D405/14 , C07D413/04 , C07D419/04 , C07D471/04 , C07F9/572 , C07F9/59
Abstract: Processes for preparing endothelin antagonists of formula (I) and pharmaceutically acceptable salts thereof and processes for preparing intermediates thereof.
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