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公开(公告)号：FI91421C
公开(公告)日：1994-06-27
申请号：FI873948
申请日：1987-09-11
Applicant: BASF AG
Inventor： MOELLER ACHIM , EMLING FRANZ
IPC: G01N33/53 , A61K39/395 , A61P29/00 , A61P31/04 , A61P35/00 , C07H21/04 , C07K14/00 , C07K14/005 , C07K14/195 , C07K14/52 , C07K14/525 , C07K16/00 , C07K16/24 , C12N5/10 , C12N5/20 , C12N15/00 , C12N15/02 , C12P21/00 , C12P21/08 , C12R1/91 , G01N33/577 , C12N5/00 , C07K15/04
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公开(公告)号：CA2051124A1
公开(公告)日：1991-01-30
申请号：CA2051124
申请日：1990-07-20
Applicant: BASF AG
Inventor： DOERPER THOMAS , HILLEN HEINZ , EMLING FRANZ , DAUM LOTHAR , MOELLER ACHIM
IPC: A61K38/00 , A61P29/00 , A61P31/04 , A61P37/06 , C07K14/47 , C07K14/52 , C07K14/525 , C07K19/00 , C12N1/21 , C12N5/24 , C12N15/09 , C12P21/02 , C12R1/19 , C12N15/62 , A61K38/19 , C12N15/28
Abstract: O.Z. 0050/40983 Proteins with TNF action Derivatives of tumor necrosis factor (TNF), which are derived from the TNF molecule by an alteration at the amino terminus, and the preparation thereof are described. The proteins are suitable for controlling diseases.
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公开(公告)号：AU600131B2
公开(公告)日：1990-08-02
申请号：AU1615188
申请日：1988-05-13
Applicant: BASF AG
Inventor： DOERPER THOMAS , MOELLER ACHIM , HILLEN HEINZ , KEILHAUER GERHARD , EMLING FRANZ , DAUM LOTHAR
IPC: C12N15/09 , A61K38/00 , A61P35/00 , C07K1/20 , C07K14/00 , C07K14/52 , C07K14/525 , C07K14/78 , C07K19/00 , C12P21/02 , C12R1/19 , C12N15/00 , C07K13/00 , A61K37/02 , A61K37/43 , C12N15/62
Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.
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公开(公告)号：FI882283A0
公开(公告)日：1988-05-16
申请号：FI882283
申请日：1988-05-16
Applicant: BASF AG
Inventor： DOERPER THOMAS , MOELLER ACHIM , HILLEN HEINZ , KEILHAUER GERHARD , EMLING FRANZ , DAUM LOTHAR
IPC: C12N15/09 , A61K38/00 , A61P35/00 , C07K1/20 , C07K14/00 , C07K14/52 , C07K14/525 , C07K14/78 , C07K19/00 , C12P21/02 , C12R1/19 , C12N
Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.
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公开(公告)号：AU749539B2
公开(公告)日：2002-06-27
申请号：AU9068398
申请日：1998-07-23
Applicant: BASF AG
Inventor： STEINER GERD , DULLWEBER UTA , STARCK DOROTHEA , BACH ALFRED , WICKE KARSTEN , TESCHENDORF HANS-JURGEN , GARCIA-LADONA FRANCISCO JAVIER , EMLING FRANZ
IPC: A61K31/435 , A61P25/24 , C07D495/14
Abstract: 3-Substituted 3,4,5,7-tetrahydropyrrolo[3',4':4,5]thieno-[2,3-d]pyrimidine derivatives of the formula Iin which the substituents have the meanings stated in the description, their preparation and their use as drugs.
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Patent Agency Ranking
公开(公告)号：NO20013409L
公开(公告)日：2001-08-30
申请号：NO20013409
申请日：2001-07-10
Applicant: BASF AG
Inventor： STEINLER GERD , SCHELLHAAS KURT , LUBISCH WILFRIED , HOLZENKAMP UTA , STARCK DOROTHEA , KNOPP MONIKA , SZABO LASZLO , EMLING FRANZ , GARCIA-LADONA FRANCISCO-JAVIER , HOFMANN HANS PETER , UNGER LILIANE
IPC: C07D495/04 , A61K31/505 , A61K31/519 , A61P9/10 , C07D495/14
Abstract: Use of pyrimidine derivatives of the formula Iwhere the substituents are as defined in the description, and of their physiologically tolerated salts for producing medicaments for the prophylaxis and treatment of cerebral ischemia and strokes.
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47.发明专利
公开(公告)号：BG104291A
公开(公告)日：2001-05-31
申请号：BG10429100
申请日：2000-04-03
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , DULLWEBER UTA , STARCK DOROTHEA , STEINER GERD , BACH ALFRED , EMLING FRANZ , GARCIA-LADONA XAVIER , TESCHENDORF HANS-JUERGEN , WICKE KARSTEN
IPC: A61K31/519 , A61P1/00 , A61P1/14 , A61P3/04 , A61P5/00 , A61P9/12 , A61P15/00 , A61P25/00 , A61P25/22 , A61P25/24 , A61P25/28 , A61P43/00 , C07D471/00 , C07D471/04
Abstract: The invention relates to new 3-substituted tetrahydropyridopyrimidinone derivatives with the formula where the substituents have the meanings given in the Description, to methods for producing said derivatives, and to their use as medicamentous forms. 7 claims
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公开(公告)号：BG104151A
公开(公告)日：2000-10-31
申请号：BG10415100
申请日：2000-02-10
Applicant: BASF AG
Inventor： STEINER GERD , DULLWEBER UTA , STARCK DOROTHEA , BACH ALFRED , WICKE KARSTEN , TESCHENDORF HANS-JUERGEN , GARCIA-LADONA FRANCISCO X , EMLING FRANZ
IPC: A61K31/435 , A61P25/24 , C07D495/14
Abstract: The invention relates to new 3-substituted 3,4,5,7-tetrahydropyrolo[3',4':4,5] thieno] pyrimidine derivatives with the formula where the substituents have the meanings listed in the description, to their preparation and application as medicamentous forms. 6 claims
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公开(公告)号：AU725170B2
公开(公告)日：2000-10-05
申请号：AU6124296
申请日：1996-06-03
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA A
Abstract: Novel compounds of the formulaR1R2N-CHX-CO-A-B-D-(E)s-(F)t-(G)U-KIin which R1, R2, A, B, D, E, F, G, K, X, s, t, and u have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：AU725164B2
公开(公告)日：2000-10-05
申请号：AU6124196
申请日：1996-06-03
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA A
Abstract: Novel compounds of the formulaR1R2N-CHX-CO-A-B-D-(E)s-(F)t-(G)U-KIin which R1, R2, A, B, D, E, F, G, K, X, s, t, and u have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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