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    SYSTEMS AND METHODS FOR ERADICATING CONTAMINANTS USING PHOTOACTIVE MATERIALS IN FLUIDS LIKE BLOOD USING DISCRETE SOURCES OF RADIATION
    41.
    发明专利
    SYSTEMS AND METHODS FOR ERADICATING CONTAMINANTS USING PHOTOACTIVE MATERIALS IN FLUIDS LIKE BLOOD USING DISCRETE SOURCES OF RADIATION 未知

    公开(公告)号：ZA919934B

    公开(公告)日：1992-09-30

    申请号：ZA919934

    申请日：1991-12-18

    Applicant: BAXTER INT

    Inventor： WOLF LUDWIG JR ,  LUDWIG WOLF JR ,  FOLEY JOHN T ,  JOHN T FOLEY ,  BRATTEN WILLIAM R ,  WILLIAM R BRATTEN

    IPC: A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61M1/36 ,  B01J19/12 ,  A61M

    Abstract: A system and method for treating a fluid carrying a contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method also channel the flow of fluid in the gap in succession through one or more flow paths. The system and method establish at least two discrete sources of radiation in the flow path at spaced apart locations along the direction of fluid flow. At least one of the radiation sources comprises a photodiode. The system and method further include a control for operating each discrete source of radiation at a selected wavelength within the prescribed range to activate the photoactive material bound to the contaminant. Upon activation, the material eradicates the contaminant. The system and method provide extracorporeal treatment of fluids like blood to quickly and effectively eradicate infection agents at relatively high flow rates.

    42.
    发明专利
    未知

    公开(公告)号：DE60037827D1

    公开(公告)日：2008-03-06

    申请号：DE60037827

    申请日：2000-10-12

    Applicant: BAXTER INT

    Inventor： BROWN RICHARD I ,  FOLEY JOHN T ,  PATNO TIMOTHY J

    IPC: B01D17/12 ,  G01N33/49 ,  A61M1/02 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B04B5/04 ,  B04B13/00 ,  G01N21/59

    Abstract: Blood processing systems and methods separate blood into constituents including a plasma constituent that includes a platelet volume. The systems and methods detect the optical density of the plasma constituent and generate a first output indicative of the optical density. A processing element integrates the first output relative to the volume of plasma constituent and generates an integrated output. The integrated output correlates to the platelet volume. A second processing element generates an output based, at least in part, upon the integrated output, which comprises a value indicating a blood volume that needs be processed to obtain a desired platelet volume.

    TIME BASED INTERFACE DETECTION SYSTEMS FOR BLOOD PROCESSING APPARATUS
    43.
    发明专利
    TIME BASED INTERFACE DETECTION SYSTEMS FOR BLOOD PROCESSING APPARATUS 未知

    公开(公告)号：CA2124812C

    公开(公告)日：2004-06-01

    申请号：CA2124812

    申请日：1993-03-23

    Applicant: BAXTER INT

    Inventor： BROWN RICHARD I ,  FOLEY JOHN T

    IPC: A61M1/02 ,  A61M1/30 ,  B01D21/26 ,  B04B5/00 ,  B04B5/04 ,  B04B5/12

    Abstract: A system (234) for monitoring the interface region between cellular constituents and plasma in a blood separation chamber (80) employs a sensor mechanism (236) for emitting upon the interface region energy that is absorbed by the cellular constituents. The sensor mechanism (244) also detects the intensity of the energy that is not absorbed by the interface region to generate an unabsorbed intensity output signal. The system (234) moves the interface region relative to the sensor mechanism during a prescribed time period. A first circuit (268) measures variations in the unabsorbed intensity output signal over the prescribed time period and generates a time based output. A second circuit (270) can derive the physical size of the interface region based upon the time based output.

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