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    AUTOMATED ACQUISITION OF SPECTRAL DATA AND IMAGE DATA
    42.
    发明申请
    AUTOMATED ACQUISITION OF SPECTRAL DATA AND IMAGE DATA 审中-公开
    自动采集光谱数据和图像数据

    公开(公告)号：WO2007050602A3

    公开(公告)日：2009-05-14

    申请号：PCT/US2006041471

    申请日：2006-10-24

    Applicant: CHEMIMAGE CORP ,  MAIER JOHN S ,  TREADO PATRICK J ,  NELSON MATTHEW ,  MCCLELLAND LINDY ,  STEWART SHONA

    Inventor： MAIER JOHN S ,  TREADO PATRICK J ,  NELSON MATTHEW ,  MCCLELLAND LINDY ,  STEWART SHONA

    IPC: G01J3/44 ,  G06F19/00 ,  H04B10/08 ,  H04B17/00

    CPC classification number: G01N21/65 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/274 ,  G01N2021/656

    Abstract: A system and method to automatically obtain spectra for samples. The method involves a two phase process including a photobleaching phase and a spectral acquisition phase. In the photobleaching phase, a series of spectral data sets of a sample are collected. A relative difference is determined between the background of subsequent spectral data sets is determined and compared to a predetermined threshold value. If threshold difference is less than the relative difference between the background of subsequent spectral data sets, the steps of collecting a series of spectra data sets is automatically repeated. In the spectrum acquisition phase, a series of Raman data sets of the sample are collected until a target SNR is obtained.

    Abstract translation: 自动获取样品光谱的系统和方法。 该方法涉及包括光漂白相和光谱采集阶段的两相过程。 在漂白漂白阶段，收集样品的一系列光谱数据集。 在确定后续光谱数据集的背景并将其与预定阈值进行比较之间确定相对差。 如果阈值差小于随后的光谱数据集的背景之间的相对差，则自动重复收集一系列光谱数据集的步骤。 在频谱采集阶段，收集样本的一系列拉曼数据集，直到获得目标SNR。

    METHOD AND SYSTEM FOR COMBINED RAMAN AND LIBS DETECTION
    43.
    发明申请
    METHOD AND SYSTEM FOR COMBINED RAMAN AND LIBS DETECTION 审中-公开
    用于组合拉曼和LIBS检测的方法和系统

    公开(公告)号：WO2007087315A3

    公开(公告)日：2008-07-31

    申请号：PCT/US2007001799

    申请日：2007-01-23

    Applicant: CHEMIMAGE CORP ,  BECKSTEAD JEFFREY ,  TREADO PATRICK J ,  NELSON MATTHEW ,  HUBBLE HUGH W II ,  NEISS JASON

    Inventor： BECKSTEAD JEFFREY ,  TREADO PATRICK J ,  NELSON MATTHEW ,  HUBBLE HUGH W II ,  NEISS JASON

    IPC: G01J3/44

    CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0272 ,  G01J3/28 ,  G01J3/443 ,  G01N21/65 ,  G01N21/718

    Abstract: In one embodiment, the disclosure relates to a method for interrogating a sample by: illuminating a first region of the sample with a first illumination pattern to obtain a plurality of first sample photons; illuminating a second region of the sample with a second illumination pattern to obtain a plurality of second sample photons; processing the plurality of first sample photons to obtain a characteristic atomic emission of the first region and processing the plurality of second sample photons to obtain a Raman spectrum; and identifying the sample through at least one of the characteristic atomic emission of the first region or the Raman spectrum of the second region of the sample.

    Abstract translation: 在一个实施例中，本公开涉及一种用于询问样本的方法，其中：用第一照明图案照射样品的第一区域以获得多个第一样品光子; 用第二照明图案照射样品的第二区域以获得多个第二样品光子; 处理多个第一样品光子以获得第一区域的特征原子发射并处理多个第二样品光子以获得拉曼光谱; 以及通过样品的第二区域的第一区域的特征性原子发射或拉曼光谱中的至少一个来识别样品。

    SYSTEM AND METHOD FOR ROBOT MOUNTED SENSOR
    45.
    发明申请
    SYSTEM AND METHOD FOR ROBOT MOUNTED SENSOR 审中-公开
    机器人安装传感器的系统和方法

    公开(公告)号：WO2007032814A3

    公开(公告)日：2008-01-10

    申请号：PCT/US2006027172

    申请日：2006-07-12

    Applicant: CHEMIMAGE CORP ,  TREADO PATRICK J ,  GARDNER CHARLES W

    Inventor： TREADO PATRICK J ,  GARDNER CHARLES W

    IPC: G01N21/00 ,  G01J3/28 ,  G01J3/44

    CPC classification number: G01N21/474 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/027 ,  G01J3/0278 ,  G01J3/0291 ,  G01J3/44

    Abstract: An apparatus and method for the remote analysis and identification of unknown compounds. A robotic arm positions a sensor on a surface. The sensor unit has a monitoring mechanism to monitor separation between the sensor unit and the surface when placed in contact with the surface to maintain the separation substantially constant. An illumination source illuminates the region of interest to produce scattered photons from an unknown compound. The scattered photons are collected by an optical system and delivered to a spectroscopic detector for analysis and identification. An algorithm is applied to the data generated by the spectroscopic detector to identify the unknown compound.

    Abstract translation: 用于远程分析和鉴定未知化合物的装置和方法。 机器手臂将传感器定位在表面上。 传感器单元具有监测机构，用于在放置与表面接触时监测传感器单元与表面之间的分离，以保持分离基本恒定。 照明源照亮感兴趣的区域以产生来自未知化合物的散射光子。 散射的光子被光学系统收集并传送到光谱检测器进行分析和识别。 将一种算法应用于由光谱检测器产生的数据，以识别未知化合物。

    MOTION INVARIANT GENERALIZED HYPERSPECTRAL TARGETING AND IDENTIFICATION METHODOLOGY AND APPARATUS THEREFOR
    46.
    发明申请
    MOTION INVARIANT GENERALIZED HYPERSPECTRAL TARGETING AND IDENTIFICATION METHODOLOGY AND APPARATUS THEREFOR 审中-公开
    运动不变广义高光谱目标识别方法及其设备

    公开(公告)号：WO2007044594A3

    公开(公告)日：2007-07-19

    申请号：PCT/US2006039271

    申请日：2006-10-10

    Applicant: CHEMIMAGE CORP ,  TREADO PATRICK J ,  NEISS JASON H

    Inventor： TREADO PATRICK J ,  NEISS JASON H

    IPC: G01N33/00

    CPC classification number: G01N21/6456 ,  G01J3/2823 ,  G01N21/359 ,  G01N21/65 ,  G01N33/0004 ,  G01N2021/1793 ,  G01N2021/3531 ,  G01N2021/6423

    Abstract: The present disclosure relates to a method and system for enhancing the ability of nuclear, chemical, and biological ("NBC") sensors, specifically mobile sensors, to detect, analyze, and identify NBC agents on a surface, in an aerosol, in a vapor cloud, or other similar environment. Embodiments include the use of a two-stage approach including targeting and identification of a contaminant. Spectral imaging sensors may be used for both wide-field detection (e.g., for scene classification) and narrow-field identification.

    Abstract translation: 本公开涉及一种用于增强核，化学和生物（“NBC”）传感器，特别是移动传感器在表面上，以气溶胶形式检测，分析和识别NBC剂的能力的方法和系统， 蒸气云或其他类似的环境。 实施例包括使用包括污染物的定向和识别的两阶段方法。 光谱成像传感器可以用于宽视场检测（例如，用于场景分类）和窄视场识别。

    INVASIVE AND NON-INVASIVE CHEMOMETRY
    47.
    发明申请
    INVASIVE AND NON-INVASIVE CHEMOMETRY 审中-公开
    侵入性和无侵入性的化学计量学

    公开(公告)号：WO2007055981A3

    公开(公告)日：2007-07-05

    申请号：PCT/US2006042538

    申请日：2006-11-01

    Applicant: CHEMIMAGE CORP ,  TREADO PATRICK J ,  MAIER JOHN S ,  COHEN JEFFREY K ,  DEMUTH JOSEPH E

    Inventor： TREADO PATRICK J ,  MAIER JOHN S ,  COHEN JEFFREY K ,  DEMUTH JOSEPH E

    IPC: A61B5/00

    CPC classification number: G06F19/10 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/415 ,  A61B5/418 ,  A61B5/4519

    Abstract: The invention relates to methods and devices for assessing one or more components of blood or a selected tissue in an animal. The present invention permits non-invasive assessment of blood or tissue components in a body structure containing multiple tissue types by assessing multiple regions of the animal's body for an optical characteristic of the blood or the tissue of interest and separately assessing one or more optical (e.g., Raman or NIR) characteristics of the blood or tissue component for one or more regions that exhibit the optical characteristic of the blood or the tissue of interest.

    Abstract translation: 本发明涉及用于评估动物中血液或选定组织的一种或多种成分的方法和装置。 本发明允许通过针对血液或感兴趣组织的光学特性评估动物身体的多个区域并分别评估一个或多个光学（例如， 拉曼或NIR）特征的一个或多个区域，其显示血液或目标组织的光学特性。

    SYSTEM AND METHOD FOR SPECTROSCOPY AND IMAGING
    48.
    发明申请
    SYSTEM AND METHOD FOR SPECTROSCOPY AND IMAGING 审中-公开
    用于光谱学和成像的系统和方法

    公开(公告)号：WO2006007064A3

    公开(公告)日：2006-04-20

    申请号：PCT/US2005016141

    申请日：2005-05-06

    Applicant: CHEMIMAGE CORP ,  STEWART SHONA ,  NELSON MATTHEW P ,  DEMUTH JOSEPH E ,  TREADO PATRICK J

    Inventor： STEWART SHONA ,  NELSON MATTHEW P ,  DEMUTH JOSEPH E ,  TREADO PATRICK J

    IPC: G01J3/44 ,  G01N21/65

    CPC classification number: G01J3/44 ,  G01J3/0297 ,  G01N21/65

    Abstract: The disclosure relates to a substrate material for the improved detection, resolution and imaging of biological material for spectroscopic characterization by Raman of optical imaging spectroscopy. The substrate provides a uniform, optically flat, highly reflective surface which can be made hydrophobic to prevent spreading of the sample and facilitating its optical evaluation. Moreover, the substrate can be coated with a material that does not emit Raman scattered photons when exposed to said illuminating photons. The principles disclosed herein allow a low spectroscopic background particularly suitable for examining small samples or samples having low concentrations of the suspected component.

    Abstract translation: 本公开涉及一种用于改进的光学成像光谱术的拉曼光谱表征的生物材料的检测，分辨率和成像的基底材料。 基材提供均匀的，光学平坦的高度反射表面，其可以制成疏水性的，以防止样品扩散并促进其光学评估。 此外，衬底可以涂覆有当暴露于所述照射光子时不发射拉曼散射光子的材料。 本文公开的原理允许特别适用于检查小样品或具有低浓度可疑成分的样品的低光谱背景。

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