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    44.
    发明专利
    未知

    公开(公告)号：SE407938B

    公开(公告)日：1979-04-30

    申请号：SE7406595

    申请日：1974-05-17

    Applicant: HOECHST AG

    Inventor： KUNSTMANN R ,  GRANZER E

    IPC: C07D221/16

    Abstract: Partially hydrogenated 1H-indeno[1,2-b]-pyridine derivatives of the general formula I in which R1 and R2, which may be identical or different, represent hydrogen, halogen or alkoxy of 1 to 4 carbon atoms, R3 represents pyridyl, phenyl, or phenyl mono- or di-substituted by halogen, nitro, amino, acylamino, alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, or amino substituted by 1 or 2 aliphatic or aromatic hydrocarbon groups having 2 to 18 carbon atoms or substituted amino wherein the amino-nitrogen is included in a heterocycle, A represents a single or double bond, and X represents oxygen or sulfur, AND THEIR PHYSIOLOGICALLY TOLERATED SALTS, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.

    O-ALKYLATED OXIMES
    45.
    发明专利
    O-ALKYLATED OXIMES 未知

    公开(公告)号：ZA777584B

    公开(公告)日：1978-11-29

    申请号：ZA777584

    申请日：1977-12-21

    Applicant: HOECHST AG

    Inventor： GEBERT U ,  GREVE H ,  GRANZER E ,  THORWART W

    IPC: C07D295/08 ,  A61K31/445 ,  A61K31/451 ,  A61K31/495 ,  A61P3/06 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  A61P19/06 ,  C07D209/14 ,  C07D211/14 ,  C07D213/53 ,  C07D213/80 ,  C07D295/088 ,  C07D303/12 ,  C07D303/36 ,  C07D333/22 ,  C07D409/12 ,  A61K31/15 ,  A61K31/50 ,  C07C131/00

    Abstract: Compounds of general formula (I) wherein R1 represents a member selected from the group consisting of (a) an unsubstituted at most binuclear aryl group having from 6 to 10 carbon atoms, such groups substituted by from 1 to 3 equal or different radicals selected from the group consisting of alkyl, halogenoalkyl, alkoxy, dialkylamino each having up to 4 carbon atoms in the alkyl moiety, halogen phenyl, carboxyl, cyano, nitro and hydroxy groups, (b) a 5- to 6-membered heteroaromatic ring wherein the heteroatom is selected from nitrogen, oxygen and sulfur atoms and such rings anellated to a benzene nucleus; R2 represents a member selected from the group consisting of hydrogen, alkyl having up to 3 carbon atoms, phenyl, cycloalkyl having up to 6 carbon atoms in the ring and cycloalkyl bearing a hydrocarbon bridging radical having up to 2 carbon atoms; R3 represents hydrogen, hydroxy or acyloxy; R4 and R5 are the same or different and each represents a member selected from the group consisting of halogen, alkyl, and halogenoalkyl each having up to 3 carbon atoms, and nitro; and X represents nitrogen or methine and physiologically acceptable acid addition salts thereof and a pharmaceutical composition containing said compounds.

    46.
    发明专利
    未知

    公开(公告)号：DK391677A

    公开(公告)日：1978-03-05

    申请号：DK391677

    申请日：1977-09-02

    Applicant: HOECHST AG

    Inventor： WEYER R ,  HITZEL V ,  GRANZER E

    IPC: A61K31/195 ,  A61K31/38 ,  A61K31/381 ,  A61P3/06 ,  C07C229/38 ,  C07C233/81 ,  C07C235/52 ,  C07D333/38 ,  C07C

    Abstract: Benzoic acids of the general formula I I in which R, R1, R2 and Y have the meanings as mentioned in the following, and which in the form of the free compounds or in the form of the physiologically tolerated salts and esters possess valuable pharmacological properties, processes for preparing them, pharmaceutical preparations containing them, and their use as or in medicaments.

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