公开(公告)号：AT22182T

公开(公告)日：1986-09-15

申请号：AT82109830

申请日：1982-10-25

Applicant: MILES LAB

Inventor： ATKINSON DAVID C ,  CARRICO ROBERT J ,  MORRIS DAVID L

IPC: G01N33/78

公开(公告)号：CA1208547A

公开(公告)日：1986-07-29

申请号：CA414812

申请日：1982-11-03

Applicant: MILES LAB

Inventor： ATKINSON DAVID C ,  CARRICO ROBERT J ,  MORRIS DAVID L

IPC: G01N33/78 ,  G01N33/566 ,  G01N33/573

Abstract: An improved immunoassay method, reagent means, and test kit for determining an iodothyronine, e.g., thyroxine (T-4), in a biological fluid, usually serum or plasma, wherein fenclofenac and related phenylacetic acids, or salts thereof, are employed as novel blocking agents for the binding of iodothyronines to thyroxine binding protein (TBP). The present invention is particularly advantageous as applied to homogeneous competitive binding iodothyronine immunoassays wherein a spectrophotometric response is generated in the assay reaction mixture at a wavelength greater than about 300 nm, the blocking agents of the present invention having been found to have no substantial absorbance at wavelengths above 300 nm. Such homogeneous immunoassays include those which employ labels such as fluorescers, enzyme substrates, enzyme prosthetic groups, enzymes, and enzyme inhibitors.

公开(公告)号：DK242685A

公开(公告)日：1985-12-02

申请号：DK242685

申请日：1985-05-30

Applicant: MILES LAB

Inventor： CARRICO ROBERT J

IPC: C07H21/00 ,  C07K16/00 ,  C07K16/44 ,  C12N5/10 ,  C12N15/02 ,  C12P21/08 ,  C12Q1/68 ,  C12R1/91 ,  G01N33/53 ,  G01N33/543 ,  G01N33/577 ,  G01N

公开(公告)号：ZA849595B

公开(公告)日：1985-07-31

申请号：ZA849595

申请日：1984-12-10

Applicant: MILES LAB

Inventor： CARRICO ROBERT J

IPC: G01N33/50 ,  A61K39/00 ,  C07H20060101 ,  C07H21/00 ,  C07H21/04 ,  C12N15/00 ,  C12N15/09 ,  C12Q20060101 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/58 ,  C07H ,  C12Q

公开(公告)号：AU3656384A

公开(公告)日：1985-06-20

申请号：AU3656384

申请日：1984-12-12

Applicant: MILES LAB

Inventor： CARRICO ROBERT J

IPC: C12Q1/68 ,  G01N20060101 ,  G01N33/53 ,  G01N33/54

公开(公告)号：AU3656184A

公开(公告)日：1985-06-20

申请号：AU3656184

申请日：1984-12-12

Applicant: MILES LAB

Inventor： CARRICO ROBERT J

IPC: C12Q1/68 ,  G01N20060101 ,  G01N33/52 ,  G01N33/53

公开(公告)号：DK591984A

公开(公告)日：1985-06-13

申请号：DK591984

申请日：1984-12-11

Applicant: MILES LAB

Inventor： ALBARELLA JAMES P ,  ANDERSON LESLIE H ,  CARRICO ROBERT J

IPC: C07K16/18 ,  C12Q1/68 ,  C12Q1/70 ,  G01N ,  C12Q

公开(公告)号：DK591484A

公开(公告)日：1985-06-13

申请号：DK591484

申请日：1984-12-11

Applicant: MILES LAB

Inventor： ALBARELLA JAMES P ,  ANDERSON LESLIE H ,  CARRICO ROBERT J

IPC: C07K16/18 ,  C12Q1/68 ,  C12Q1/70 ,  G01N33/542 ,  C12Q ,  G01N

公开(公告)号：NO844561A

公开(公告)日：1985-05-31

申请号：NO844561

申请日：1984-11-15

Applicant: MILES LAB

Inventor： BLAKE DIANE A ,  BOGUSLASKI ROBERT C ,  CARRICO ROBERT J ,  SKARSTEDT MARK T

IPC: G01N33/535 ,  G01N33/542 ,  G01N33/58 ,  G01N

CPC classification number: G01N33/542 ,  G01N33/535 ,  G01N33/581

公开(公告)号：DK568684A

公开(公告)日：1985-05-31

申请号：DK568684

申请日：1984-11-29

Applicant: MILES LAB

Inventor： BLAKE DIANE A ,  BOGUSLASKI ROBERT C ,  CARRICO ROBERT J ,  SKARSTEDT MARK T

IPC: G01N33/535 ,  G01N33/542 ,  G01N33/58 ,  C12Q