公开(公告)号：WO0204112A3

公开(公告)日：2002-05-16

申请号：PCT/US0121718

申请日：2001-07-09

Applicant: SYMYX TECHNOLOGIES INC

Inventor： HAGEMEYER ALFRED ,  VOLPE ANTHONY F JR ,  LEFORT LAURENT ,  LUGMAIR CLAUS ,  LOWE DAVID M ,  LIU YUMIN ,  BERGH H SAM ,  GUAN SHENHENG ,  PINKAS DANIEL M ,  ENGSTROM JAMES R ,  SELF KYLE W

IPC: B01J19/00 ,  B01J37/00 ,  C40B30/08 ,  C40B40/18 ,  G01N31/10

CPC classification number: B07B1/00 ,  B01J19/0046 ,  B01J35/10 ,  B01J37/0036 ,  B01J37/009 ,  B01J2219/00313 ,  B01J2219/00319 ,  B01J2219/00351 ,  B01J2219/00481 ,  B01J2219/00484 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/007 ,  B01J2219/00704 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/00756 ,  B01L3/5025 ,  B22F2998/00 ,  C40B30/08 ,  C40B40/18 ,  G01N31/10 ,  B22F9/04

Abstract: Protocols for designing and implementing sets of simultaneous experiments, in a parallel, multi-variable process optimization reactor, are disclosed. The multi-variable process optimization reactor is preferably a parallel flow reactor having the operational capability to simultaneously vary reaction conditions between reaction vessels - either modularly or independently. The simultaneously varied reaction conditions preferably include at least two of the following, in various combinations and permutations: space velocity, contact time, temperature, pressure and feed composition. Compositional variations in the catalysts residing in each of the reaction vessels can also be investigated in the set of simultaneous experiments implemented in the parallel reactor. Sufficient data is obtained from a single set of simultaneous experiments to generate a master curve.

公开(公告)号：WO0166245A3

公开(公告)日：2002-04-25

申请号：PCT/US0107372

申请日：2001-03-07

Applicant: SYMYX TECHNOLOGIES INC ,  BERGH H SAM ,  ENGSTROM JAMES R ,  GUAN SHENHENG ,  PINKAS DANIEL MERON ,  SELF KYLE W

Inventor： BERGH H SAM ,  ENGSTROM JAMES R ,  GUAN SHENHENG ,  PINKAS DANIEL MERON ,  SELF KYLE W

IPC: B01J4/00 ,  B01J19/00 ,  B01L3/00 ,  C40B30/08 ,  C40B40/18 ,  C40B60/14

CPC classification number: B01L7/525 ,  B01J4/00 ,  B01J19/004 ,  B01J19/0046 ,  B01J19/0093 ,  B01J2219/00038 ,  B01J2219/00306 ,  B01J2219/00317 ,  B01J2219/00319 ,  B01J2219/00351 ,  B01J2219/00389 ,  B01J2219/00452 ,  B01J2219/00479 ,  B01J2219/00585 ,  B01J2219/0068 ,  B01J2219/00698 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/00783 ,  B01J2219/00891 ,  B01J2219/00952 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502746 ,  B01L7/54 ,  B01L2200/143 ,  B01L2300/0883 ,  B01L2400/06 ,  C40B30/08 ,  C40B40/18 ,  C40B60/14 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

Abstract: Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise one or more subsystems, including for example, a flow-partitioning subsystem for providing a different flow rate to each of the four or more reactors, a pressure-partitioning subsystem for providing a different reaction pressure in the reaction cavity of each of the four or more reactors, and a feed-composition subsystem for providing a different feed composition to each of the four or more reactors. In preferred embodiments, the one or more subsystems can comprise at least one set of four or more flow restrictors, each of the four or more flow restrictors having a flow resistance that varies relative to other flow restrictors in the set.

公开(公告)号：WO0051720A2

公开(公告)日：2000-09-08

申请号：PCT/US0005572

申请日：2000-03-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： BERGH S HOWARD ,  GUAN SHENHENG

IPC: B01F5/06 ,  B01J19/00 ,  B01L3/00 ,  B01L7/00 ,  C01B3/40 ,  C07C17/23 ,  C07C45/34 ,  C07C45/35 ,  C07C45/38 ,  C07C45/46 ,  C07C45/50 ,  C07C45/54 ,  C07C45/72 ,  C40B30/08 ,  C40B40/18 ,  G01N30/90 ,  G01N31/10 ,  G01N35/00 ,  G01N35/02

CPC classification number: B01L3/5027 ,  B01F5/0601 ,  B01F15/0264 ,  B01J19/0046 ,  B01J19/0093 ,  B01J2219/00286 ,  B01J2219/00306 ,  B01J2219/00308 ,  B01J2219/00337 ,  B01J2219/00353 ,  B01J2219/00389 ,  B01J2219/00418 ,  B01J2219/00452 ,  B01J2219/00479 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00641 ,  B01J2219/00657 ,  B01J2219/00659 ,  B01J2219/00704 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/00783 ,  B01J2219/00835 ,  B01J2219/00871 ,  B01L3/0293 ,  B01L3/5025 ,  B01L3/502707 ,  B01L7/54 ,  B01L2300/0864 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/14 ,  B01L2300/18 ,  B01L2400/0487 ,  C01B3/40 ,  C07C17/23 ,  C07C45/34 ,  C07C45/35 ,  C07C45/38 ,  C07C45/46 ,  C07C45/54 ,  C07C45/72 ,  C40B30/08 ,  C40B40/18 ,  G01N30/90 ,  G01N31/10 ,  G01N35/028 ,  G01N2035/00158 ,  C07C47/06 ,  C07C47/22 ,  C07C47/04 ,  C07C49/403 ,  C07C47/127 ,  G01N30/466

Abstract: A chemical processing microsystem useful for identifying and optimizing materials (e.g., catalysts) that enhance chemical processes or for characterizing and/or optimizing chemical processes is disclosed. The chemical processing microsystem comprises a plurality of microreactors (600) and, in a preferred embodiment, a plurality of microseparators (900) integral with the chemical processing microsystem (10). The microreactors (600) are preferably diffusion-mixed microreactors formed in a plurality of laminae that include a modular, interchangeable candidate-material array (100). The material array (100) comprises a plurality of different candidate materials (e.g., catalysts), preferably arranged at separate, individually addressable portions of a substrate (e.g., wafer). The microseparators (900) are similarly formed in a plurality of laminae that include a modular, interchangeable adsorbent array (700). The adsorbent array (700) comprises one or more adsorbents, preferably arranged at separate, individually addressable portions of a substrate to spatially correspond to the plurality of different candidate materials. Modular microfluidic distribution systems are also disclosed. The chemical processing microsystem can be integrated into a material evaluation system that enables a comprehensive combinatorial material science research program.

Abstract translation: 公开了一种用于识别和优化增强化学过程或表征和/或优化化学过程的材料（例如催化剂）的化学处理微系统。 化学处理微系统包括多个微反应器（600），并且在优选实施例中，与化学处理微系统（10）成一体的多个微分离器（900）。 微反应器（600）优选是形成在多个层中的扩散混合微反应器，其包括模块化的可互换的候选材料阵列（100）。 材料阵列（100）包括多个不同的候选材料（例如，催化剂），优选地布置在基板（例如，晶片）的单独可单独寻址的部分。 微分离器（900）类似地形成在包括模块化的可互换吸附剂阵列（700）的多个层中。 吸附剂阵列（700）包括一个或多个吸附剂，优选地布置在基板的分开的，可单独寻址的部分上，以在空间上对应于多种不同的候选材料。 还公开了模块化微流体分布系统。 化学加工微系统可以整合到材料评估系统中，实现全面的组合材料科学研究计划。