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公开(公告)号：CA2947080A1
公开(公告)日：2006-11-09
申请号：CA2947080
申请日：2006-04-28
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALASTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: C07K16/22 , A61K39/395 , A61P19/08 , C07K14/475 , C07K14/51 , C07K19/00 , C12N15/13 , C12P21/08 , G01N33/50
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：AU2006242476A1
公开(公告)日：2006-11-09
申请号：AU2006242476
申请日：2006-04-28
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： HOFFMANN KELLY SUE , HENRY ALISTAIR JAMES , WINTERS AARON GEORGE , WINKLER DAVID , ROBINSON MARTYN KIM , LU HSIENG SEN , LAWSON ALASTAIR , PASZTY CHRISTOPHER , LATHAM JOHN
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：AU2006242431A1
公开(公告)日：2006-11-09
申请号：AU2006242431
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： SHEN WENYAN , PASZTY CHRISTOPHER , HENRY ALISTAIR JAMES , GRAHAM KEVIN , POPPLEWELL ANDY , HOFFMANN KELLY SUE , WINTERS AARON GEORGE , LAWSON ALASTAIR , LU HSIENG SEN , ROBINSON MARTYN KIM , LATHAM JOHN , WINKLER DAVID
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：NO20076046A
公开(公告)日：2008-01-30
申请号：NO20076046
申请日：2007-11-23
Applicant: UCB PHARMA SA
Inventor： LATHAM JOHN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: C07K14/51 , C07K14/435 , C07K16/18 , C07K16/28
CPC classification number: C07K16/22 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K14/76 , C07K14/79 , C07K16/18 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/30
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公开(公告)号：NO20076046L
公开(公告)日：2008-01-30
申请号：NO20076046
申请日：2007-11-23
Applicant: UCB PHARMA SA
Inventor： LATHAM JOHN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: C07K14/51 , C07K14/435 , C07K16/18 , C07K16/28
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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Patent Agency Ranking
公开(公告)号：ES2689143T3
公开(公告)日：2018-11-08
申请号：ES10008795
申请日：2006-04-28
Applicant: UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTY KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Un anticuerpo de unión a esclerostina que comprende las siguientes secuencias de CDR: CDR-H1: DYIMH (SEQ ID NO: 269); CDR-H2: YINPYNDDTEYNEKFKG (SEQ ID NO: 270); CDR-H3: SIYYYDAPFAY (SEQ ID NO: 271); CDR-L1: RASQDISSYLN (SEC ID No: 239); CDR-L2: STSRLNS (SEQ ID NO: 240); y CDR-L3: QQDIKHPT (SEQ ID NO: 241).
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公开(公告)号：WO2006119107A9
公开(公告)日：2007-09-20
申请号：PCT/US2006016441
申请日：2006-04-28
Applicant: UCB SA , AMGEN INC , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
CPC classification number: C07K16/22 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K14/76 , C07K14/79 , C07K16/18 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/30
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
Abstract translation: 提供了与硬骨素蛋白表位有关的组合物和方法，以及硬骨素结合剂，例如能结合硬化蛋白的抗体。
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公开(公告)号：WO2006119107A3
公开(公告)日：2006-12-28
申请号：PCT/US2006016441
申请日：2006-04-28
Applicant: UCB SA , AMGEN INC , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
CPC classification number: C07K16/22 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K14/76 , C07K14/79 , C07K16/18 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/30
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
Abstract translation: 提供了与硬骨素蛋白表位有关的组合物和方法，以及硬骨素结合剂，例如能结合硬化蛋白的抗体。
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公开(公告)号：WO2006119062A3
公开(公告)日：2007-06-28
申请号：PCT/US2006016345
申请日：2006-04-28
Applicant: UCB SA , AMGEN INC , LU HSIENG SEN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , WINKLER DAVID , WINTERS AARON GEORGE
Inventor： LU HSIENG SEN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , WINKLER DAVID , WINTERS AARON GEORGE
CPC classification number: C07K16/18 , A61K2039/505 , C07K14/51 , C07K16/22 , C07K2317/24 , C07K2317/76 , C07K2317/92 , C12N15/63
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
Abstract translation: 提供了与硬骨素蛋白表位有关的组合物和方法，以及硬骨素结合剂，例如能结合硬化蛋白的抗体。
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公开(公告)号：ES2620684T3
公开(公告)日：2017-06-29
申请号：ES10014372
申请日：2006-04-28
Applicant: AMGEN INC
Inventor： LU HSIENG SEN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Un polipéptido que consiste en al menos una, al menos dos, al menos tres o las cuatro secuencias de aminoácidos SEQ ID NO: 5, SEQ ID NO: 2, SEQ ID NO: 3 y SEQ ID NO: 4, en el que el polipéptido induce un anticuerpo específico para esclerostina de SEQ ID NO: 1 cuando el polipéptido se administra a un animal.
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