METHOD AND DEVICE FOR CAVITY ENHANCED OPTICAL VERNIER SPECTROSCOPY
    41.
    发明申请
    METHOD AND DEVICE FOR CAVITY ENHANCED OPTICAL VERNIER SPECTROSCOPY 审中-公开
    用于增强光学维纳光谱的方法和装置

    公开(公告)号:WO2008077572A1

    公开(公告)日:2008-07-03

    申请号:PCT/EP2007/011219

    申请日:2007-12-19

    CPC classification number: G01J3/433 G01J3/10 G01J3/26 G01J3/457

    Abstract: A spectroscopic analysis of a sample (1) comprises arranging the sample (1) in a resonator cavity (10) being capable for transmitting cavity mode frequencies with a cavity mode frequency spacing, coupling pulsed source light into the resonator cavity (10), the source light comprising source comb fre- quencies with a source frequency spacing, coupling pulsed transmitted light out of the resonator cavity (10), and spectrally resolved detecting the transmitted light with a detector device (40), wherein the cavity mode frequency spacing and the source frequency spacing are detuned relative to each other, so that the transmitted light comprises transmitted comb frequencies with a spacing larger than the source frequency spacing, and the detecting step includes collecting spectral distributions of the transmitted light in dependence on relative positions of the cavity mode frequencies and the source comb frequencies, wherein the cavity mode frequencies and the source comb frequencies are varied relative to each other, so that the transmitted comb frequencies are varied within a predetermined spectral range of interest, and the spectral distributions of the transmitted light are collected such that different transmitted comb frequencies are individually resolved. Furthermore, a spectroscopic device (100) being adapted for the spectroscopic analysis of a sample (1) is described.

    Abstract translation: 样品(1)的光谱分析包括将样品(1)布置在谐振器腔(10)中,所述共振器腔(10)能够以腔模式频率间隔传输空腔模式频率,将脉冲源光耦合到谐振腔(10)中, 源光包括源频率间隔的源梳状频率,将脉冲透射光耦合到谐振器腔(10)之外,并用检测器装置(40)对光透射光进行光谱解析,其中腔模频率间隔和 源频率间隔相对于彼此失谐,使得透射光包括间隔大于源频率间隔的发射梳状频率,并且检测步骤包括根据腔模式的相对位置收集透射光的光谱分布 频率和源梳状频率,其中腔模式频率和源梳状频率为var 使得所发送的梳状频率在预期的感兴趣的频谱范围内变化,并且收集透射光的光谱分布,使得不同的发射梳状频率被单独地解析。 此外,描述适用于样品(1)的光谱分析的分光装置(100)。

    PROGRAMMABLE DIFFRACTION GRATING SENSOR
    42.
    发明申请
    PROGRAMMABLE DIFFRACTION GRATING SENSOR 审中-公开
    可编程衍射光栅传感器

    公开(公告)号:WO2004070782A3

    公开(公告)日:2004-11-11

    申请号:PCT/US2004002297

    申请日:2004-01-27

    Abstract: A programmable substance detector includes a light source, a sample cell, a programmable diffraction grating positioned to receive light from the light source and to direct diffracted light to the sample cell, and a detector associated with the cell to detect a match between a characteristic of the diffracted light and a corresponding characteristic of a substance within the cell.

    Abstract translation: 可编程物质检测器包括光源,样品池,定位成接收来自光源的光并将衍射光引导到样品池的可编程衍射光栅,以及与该电池相关联的检测器,用于检测 衍射光和细胞内物质的相应特征。

    METHODS FOR ADAPTIVE SPECTRAL, SPATIAL AND TEMPORAL SENSING FOR IMAGING APPLICATIONS
    43.
    发明申请
    METHODS FOR ADAPTIVE SPECTRAL, SPATIAL AND TEMPORAL SENSING FOR IMAGING APPLICATIONS 审中-公开
    用于成像应用的自适应光谱,空间和时间感测方法

    公开(公告)号:WO02014971A1

    公开(公告)日:2002-02-21

    申请号:PCT/US2001/025713

    申请日:2001-08-16

    Abstract: A method for adaptive spectral sensing developed for a two-dimensional image (16) made up of picture elements (14). The method calls for illuminating at least one of the picture elements with an input light (18) and deriving a time-varying spectral signal from the input light for that picture element. The time-varying spectral signal is processed with a time-varying reference signal by using a mathematical function such as convolution, multiplication, averaging, integrating, forming an inner product, match filtering, addition, subtraction or division to obtain a processed output value for the picture element and this output value is then used in determining a spectral characteristic of the input light. The time-varying spectral signal is conveniently derived by optical filtering of the input light yielding an optical time-varying spectral signal. This method can be used by itself or in combination with at least one other adaptive technique such as adaptive spatial sensing and/or adaptive temporal sensing.

    Abstract translation: 一种用于由图像元素(14)构成的二维图像(16)的自适应光谱感测方法。 该方法要求用输入光(18)照射至少一个图像元素,并从该图像元素的输入光导出时变光谱信号。 时变频谱信号通过使用诸如卷积,乘法,平均,积分,形成内积,匹配滤波,加法,减法或除法等数学函数,用时变参考信号进行处理,以获得处理后的输出值 然后将像素和该输出值用于确定输入光的光谱特性。 时变光谱信号通过对产生光时变光谱信号的输入光的光学滤波方便地得出。 该方法可以单独使用或与至少一种其他自适应技术组合使用,例如自适应空间感测和/或自适应时间感测。

    A METHOD OF CHARACTERIZING FLUORESCENT MOLECULES OR OTHER PARTICLES USING GENERATING FUNCTIONS
    44.
    发明申请
    A METHOD OF CHARACTERIZING FLUORESCENT MOLECULES OR OTHER PARTICLES USING GENERATING FUNCTIONS 审中-公开
    使用生成函数表征荧光分子或其他颗粒的方法

    公开(公告)号:WO0066985A9

    公开(公告)日:2002-02-14

    申请号:PCT/EP0003890

    申请日:2000-04-29

    Abstract: A method for characterizing fluorescent molecules or other particles in samples comprising the steps of: a) monitoring fluctuating intensity of fluorescence emitted by the molecules or other particles in at least one measurement volume of a non-uniform spatial brightness profile by measuring numbers of photon counts in primary time intervals by a single or more photon detectors, b) determining at least one distribution of numbers of photon counts, P(n), from the measured numbers of photon counts, c) determining physical quantities characteristic to said particles by fitting the distribution of numbers of photon counts P(n), wherein the fitting procedure involves calculation of a theoretical distribution function of the number of photon counts P(n) through its generating function, defined as (I).

    Abstract translation: 用于表征样品中的荧光分子或其他颗粒的方法,包括以下步骤:a)通过测量光子计数来监测在非均匀空间亮度分布的至少一个测量体积中由分子或其它颗粒发射的荧光的波动强度 通过单个或多个光子检测器在主要时间间隔中,b)从所测量的光子计数中确定光子计数数目P(n)的至少一个分布,c)通过拟合所述粒子的特征来确定所述粒子的特征量 光子计数P(n)的分布,其中拟合过程包括通过其生成函数(i)计算光子计数P(n)的数量的理论分布函数。

    測量在介質中之化合物之同一性或非同一性及濃度的方法 METHOD FOR DETERMINING THE IDENTITY OR NON-IDENTITY AND CONCENTRATION OF A CHEMICAL COMPOUND IN A MEDIUM
    45.
    发明专利
    測量在介質中之化合物之同一性或非同一性及濃度的方法 METHOD FOR DETERMINING THE IDENTITY OR NON-IDENTITY AND CONCENTRATION OF A CHEMICAL COMPOUND IN A MEDIUM 审中-公开
    测量在介质中之化合物之同一性或非同一性及浓度的方法 METHOD FOR DETERMINING THE IDENTITY OR NON-IDENTITY AND CONCENTRATION OF A CHEMICAL COMPOUND IN A MEDIUM

    公开(公告)号:TW200734625A

    公开(公告)日:2007-09-16

    申请号:TW095149925

    申请日:2006-12-29

    IPC: G01N

    Abstract: 本發明提供一種偵測介質(312)中所含之至少一種化合物V之方法。該方法包含一校驗步驟(420),其係用以確定該介質(312)中是否含有V。該方法另外包含一分析步驟(424),在該步驟中,測量該至少一種化合物V之濃度c。該校驗步驟包含以下分步驟:(a1)將該介質(312)曝露至一具有可變波長���之第一分析輻射(316),該波長���採取至少兩個不同値;(a2)在該介質(312)回應該第一分析輻射(316)而吸收及/或發射及/或反射及/或散射之輻射(324)之幫助下產生至少一個光譜響應函數A(���);(a3)藉由該至少一個光譜響應函數A(���)與至少一個型態函數R(���+������)之光譜比較形成至少一個光譜相關函數K(������),該至少一個型態函數R(���)表示一含有該化合物V之介質(312)之光譜量測函數且������為座標位移;(a4)於一型態辨識步驟(418)中檢驗該至少一個光譜相關函數K(������),且對該介質(312)中是否含有該至少一種化合物V作出結論;該分析步驟(424)包含以下分步驟:(b1)將該介質(312)曝露至具有至少一個激發波長���EX之至少一種第二分析輻射(318);(b2)在該介質(312)回應具有該波長
    ���EX之該第二分析輻射(318)而吸收及/或發射及/或反射及/或散射之具有響應波長���RES之輻射(326)的幫助下,產生至少一個光譜分析函數B(���EX,���RES),且由其推斷出該濃度c。

    Abstract in simplified Chinese: 本发明提供一种侦测介质(312)中所含之至少一种化合物V之方法。该方法包含一校验步骤(420),其系用以确定该介质(312)中是否含有V。该方法另外包含一分析步骤(424),在该步骤中,测量该至少一种化合物V之浓度c。该校验步骤包含以下分步骤:(a1)将该介质(312)曝露至一具有可变波长���之第一分析辐射(316),该波长���采取至少两个不同値;(a2)在该介质(312)回应该第一分析辐射(316)而吸收及/或发射及/或反射及/或散射之辐射(324)之帮助下产生至少一个光谱响应函数A(���);(a3)借由该至少一个光谱响应函数A(���)与至少一个型态函数R(���+������)之光谱比较形成至少一个光谱相关函数K(������),该至少一个型态函数R(���)表示一含有该化合物V之介质(312)之光谱量测函数且������为座标位移;(a4)于一型态辨识步骤(418)中检验该至少一个光谱相关函数K(������),且对该介质(312)中是否含有该至少一种化合物V作出结论;该分析步骤(424)包含以下分步骤:(b1)将该介质(312)曝露至具有至少一个激发波长���EX之至少一种第二分析辐射(318);(b2)在该介质(312)回应具有该波长 ���EX之该第二分析辐射(318)而吸收及/或发射及/或反射及/或散射之具有响应波长���RES之辐射(326)的帮助下,产生至少一个光谱分析函数B(���EX,���RES),且由其推断出该浓度c。

    Method and Apparatus for Light-Weight, Non-Invasive, Point of Care Diabetes Screening Device

    公开(公告)号:US20190200904A1

    公开(公告)日:2019-07-04

    申请号:US16312080

    申请日:2018-05-22

    Applicant: Rijul GUPTA

    Inventor: Rijul GUPTA

    Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the the first and second measurement portions. The microprocessor is configured with instructions stored in non-volatile memory to individually activate each of the light sources of the first and second pluralities of light sources and to record light intensity detected by the first and second light sources while an individual light source is activated. Each combination of an individually activated light source and one of the first and second light sensors provides a distinct measurement channel for measuring the absorption spectra of human blood and tissue.

    Multidimensional spectrometer
    50.
    发明授权
    Multidimensional spectrometer 有权
    多维光谱仪

    公开(公告)号:US09568366B2

    公开(公告)日:2017-02-14

    申请号:US14713329

    申请日:2015-05-15

    CPC classification number: G01J3/457 G01J3/433

    Abstract: A multidimensional spectrometer encodes frequency information into laser pulses so that a frequency insensitive detector may be used to collect data for a multi-dimensional spectrograph only from intensity information and knowledge of a modulation providing the encoding. In one embodiment the frequency encoding may be done by a conventional interferometer greatly simplifying construction of the spectrometer.

    Abstract translation: 多维光谱仪将频率信息编码成激光脉冲,使得频率不敏感检测器可以仅用于从提供编码的调制的强度信息和知识中收集用于多维光谱仪的数据。 在一个实施例中,频率编码可以通过传统的干涉仪来完成,这大大简化了光谱仪的结构。

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