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51.发明申请
公开(公告)号：WO2015145461A1
公开(公告)日：2015-10-01
申请号：PCT/IN2015/000141
申请日：2015-03-25
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.
CPC classification number: A61K9/2081 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2031 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/2846 , A61K9/4808 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K31/135 , A61K31/137 , A61K31/167 , A61K31/433 , A61K31/5517 , A61K2300/00
Abstract: An abuse deterrent immediate release biphasic matrix solid dosage form that releases the drug at a desired rate for quick onset of action when a single unit or prescribed units of the dosage form are orally administered but exhibits a reduced rate of release when more than the prescribed number of units, are administered.
Abstract translation: 滥用威慑立即释放双相基质固体剂型，当口服单一单位或剂型的规定单位时，以期望的速率释放药物以快速起效，但当超过规定数量时显示降低的释放速率 的单位，被管理。
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52.发明申请
公开(公告)号：WO2012140020A1
公开(公告)日：2012-10-18
申请号：PCT/EP2012/056470
申请日：2012-04-10
Applicant: BIOPROJET , SUN PHARMA ADVANCED RESEARCH COMPANY LTD , CAPET, Marc , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , THENNATI, Rajamannar , PAL, Ranjan, Kumar , SAMANTA, Biswajit , PILLAI, Muthukumaran, Natarajan , DESAI, Japan, Nitinkumar , RANA, Dijixa, Chandubhai , PRAJAPATI, Kaushik, Dhanjubhai , PATHAK, Sandeep, Pankajbhai , PANCHAL, Bhavesh, M. , ARADHYE, Jayraj, D.
Inventor： CAPET, Marc , BERREBI-BERTRAND, Isabelle , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , THENNATI, Rajamannar , PAL, Ranjan, Kumar , SAMANTA, Biswajit , PILLAI, Muthukumaran, Natarajan , DESAI, Japan, Nitinkumar , RANA, Dijixa, Chandubhai , PRAJAPATI, Kaushik, Dhanjubhai , PATHAK, Sandeep, Pankajbhai , PANCHAL, Bhavesh, M. , ARADHYE, Jayraj, D.
IPC: C07D413/10 , A61K31/454 , A61P9/10 , A61P29/00 , A61P37/06 , A61P35/00 , C07D413/14 , A61K31/5377
CPC classification number: C07D413/10 , A61K31/454 , A61K45/06 , C07D271/06
Abstract: The present invention relates to novel compounds acting as agonists at S1P (sphingosine-1-phosphate) receptors, compositions containing these compounds, use of these compounds in medicine and their process of preparation.
Abstract translation: 本发明涉及作为S1P（鞘氨醇-1-磷酸）受体的激动剂的新化合物，含有这些化合物的组合物，这些化合物在医药中的应用及其制备方法。
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公开(公告)号：WO2010119455A2
公开(公告)日：2010-10-21
申请号：PCT/IN2010/000243
申请日：2010-04-15
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD. , KHOPADE, Ajay Jaysingh , SANKALIA, Mayur , BHOWMICK, Subhas Balaram , THENNATI, Rajamannar
Inventor： KHOPADE, Ajay Jaysingh , SANKALIA, Mayur , BHOWMICK, Subhas Balaram , THENNATI, Rajamannar
IPC: A61K9/10
CPC classification number: A61K9/0024 , A61K9/1647 , A61K47/541 , A61K47/554
Abstract: The present invention relates to an injectable pharmaceutical composition comprising antipsychotic agents having basic groups.
Abstract translation: 本发明涉及包含具有碱性基团的抗精神病药的可注射药物组合物。
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54.发明申请MULTIPLE PILL ABUSE-RESISTANT IMMEDIATE RELEASE SOLID DOSAGE FORM OF HYDROCODONE 审中-公开多功能药物耐药性立即释放固体剂量剂型
公开(公告)号：WO2017009865A1
公开(公告)日：2017-01-19
申请号：PCT/IN2016/050227
申请日：2016-07-08
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.
Inventor： DHARMADHIKARI, Nitin B , ZALA, Yashoraj R , HANAMANNAVAR, Bramhanand
IPC: A61K31/485 , A61K47/32
CPC classification number: A61K9/2013 , A61K9/2027 , A61K9/2095 , A61K31/167 , A61K31/192 , A61K31/196 , A61K31/485 , A61K47/32 , A61K2300/00
Abstract: An immediate-release, abuse-resistant solid dosage form comprising melt extrudates of a mixture of: ∙ hydrocodone or its pharmaceutically acceptable salt, ∙ release inhibiting agent comprising one or more reverse enteric polymer and one or more alkalizer and ∙ one or more stabilizers.
Abstract translation: 包含立即释放，耐滥用的固体剂型，其包含以下混合物的熔融挤出物：∙氢可酮或其药学上可接受的盐，∙释放抑制剂，其包含一种或多种反式肠溶性聚合物和一种或多种碱化剂和∙一种或多种稳定剂。
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公开(公告)号：WO2016199169A1
公开(公告)日：2016-12-15
申请号：PCT/IN2016/050175
申请日：2016-06-08
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD
Inventor： MA, Wen Wee , ADJEI, Alex , BUI, Lynne , HARNING, Ronald , KHOPADE, Ajay , BHOWMICK, Subhas , ARULSUDAR, Natarajan , LAKKAD, Narendra
IPC: A61K9/107 , A61K9/51 , A61K31/337
CPC classification number: A61K9/10 , A61K9/0019 , A61K9/5123 , A61K9/5138 , A61K9/5146 , A61K31/337 , A61K47/10 , A61K47/12 , A61K47/28 , A61K47/32 , A61P35/00
Abstract: A method of treating patients suffering from carcinoma of intrahepatic or extra hepatic bile duct or gall bladder which is locally advanced or metastatic, by intravenously administering to the patient, paclitaxel in the form of a nanodispersion. The nanodispersion comprises particles with a mean particle size less than 300 nm and is free of polyoxyethylated castor oil and free of a protein.
Abstract translation: 通过静脉内施用纳米分散体形式的紫杉醇，治疗局部晚期或转移的肝内或肝外胆管癌或胆囊癌患者的方法。 纳米分散体包含平均粒度小于300nm的颗粒，并且不含聚氧乙烯化蓖麻油并且不含蛋白质。
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Patent Agency Ranking
公开(公告)号：WO2016120892A1
公开(公告)日：2016-08-04
申请号：PCT/IN2016/050032
申请日：2016-01-29
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.
CPC classification number: A61K9/284 , A61K9/2031 , A61K9/2077 , A61K9/2081
Abstract: An abuse deterrent multiparticulate solid dosage form comprising: • a first composition comprising coated cores, each coated core comprising a. a core comprising a drug susceptible to abuse and a crush resistant carrier having a first melting point b. a first coat surrounding the said core and comprising water soluble polymer, c. a second coat surrounding the first coat and optionally, a third coat, surrounding the second coat, the second and/or third coat comprising a water insoluble polymer, d. an outermost coat surrounding the inner concentric coats and consisting essentially of a reverse enteric polymer, and • a second composition comprising an alkalizer.
Abstract translation: 一种滥用威慑多颗粒固体剂型，其包含：•包含涂覆核心的第一组合物，每个涂覆的核心包含a。 包括易于滥用的药物和具有第一熔点b的抗压载体的核心。 环绕所述芯并且包含水溶性聚合物的第一涂层，c。 围绕第一涂层的第二涂层和任选地围绕第二涂层的第三涂层，第二涂层和/或第三涂层包含水不溶性聚合物，d。 围绕所述内同心涂层并且基本上由反向肠溶性聚合物组成的最外涂层，和包含碱化剂的第二组合物。
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57.发明申请
公开(公告)号：WO2015145459A1
公开(公告)日：2015-10-01
申请号：PCT/IN2015/000139
申请日：2015-03-25
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.
CPC classification number: A61K9/2081 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2031 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/2846 , A61K9/4808 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K31/135 , A61K31/137 , A61K31/167 , A61K31/433 , A61K31/5517 , A61K2300/00
Abstract: An abuse deterrent immediate release coated reservoir solid dosage form that releases the drug at a desired rate for quick onset of action when a single unit or prescribed units of the dosage form are orally administered but exhibits a reduced rate of release when more than the prescribed number of units, are administered.
Abstract translation: 滥用威慑力立即释放涂层储存器固体剂型，当口服给药单一单位或剂型的规定单位时，以期望的速率释放药物以快速起效，但当超过规定数量时，释放速率降低 的单位，被管理。
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公开(公告)号：WO2013051024A2
公开(公告)日：2013-04-11
申请号：PCT/IN2012/000521
申请日：2012-07-26
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD. , RATHOD, Rajendrasinh , BHATT, Tushar , JOSHI, Kiritkumar , DOLE, Binaka , MURTY, Kadiyala V.S.N , THENNATI, Rajamannar
Inventor： RATHOD, Rajendrasinh , BHATT, Tushar , JOSHI, Kiritkumar , DOLE, Binaka , MURTY, Kadiyala V.S.N , THENNATI, Rajamannar
IPC: C07D215/18
CPC classification number: C07D413/10 , C07D215/14 , C07D215/18 , C07D241/42 , C07D277/64 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/10 , C07D407/10 , C07D407/12 , C07D407/14 , C07D409/12
Abstract: The present invention relates to novel cysteinyl leukotriene (specifically LTD4) antagonists, mainly to quinolin, quinoxaline or benz[c]thiazole derivatives represented by the general formula (I), or the pharmaceutically acceptable salt thereof, process of preparation thereof, and to the use of the compounds in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to cysteinyl leukotriene, in mammals, more specially in humans.
Abstract translation: 本发明涉及以通式（I）表示的主要为喹啉，喹喔啉或苯并[c]噻唑衍生物的新型半胱氨酰白三烯（特别是LTD4）拮抗剂或其药学上可接受的盐，其制备方法和 在制备药物组合物中用于治疗性治疗与半胱氨酰白三烯有关的疾病，哺乳动物，更特别是在人体中的用途的用途。
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公开(公告)号：WO2012156997A2
公开(公告)日：2012-11-22
申请号：PCT/IN2012/000353
申请日：2012-05-16
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD , ZALA, Yashoraj Rupsinh , DHARMADHIKARI, Nitin , KHAN, Majed Mohammed , NABAR, Manisha
Inventor： ZALA, Yashoraj Rupsinh , DHARMADHIKARI, Nitin , KHAN, Majed Mohammed , NABAR, Manisha
IPC: A61K9/54
CPC classification number: A61K9/5078 , A61K9/2846 , A61K9/5026 , A61K9/5089 , A61K31/40
Abstract: A multi-particulate pharmaceutical composition suitable for administration in a sprinkle dosage form said particles being less than 2 mm in diameter and comprising a) inert core particles b) an inner layer surrounding said inert core particles, said layer comprising atorvastatin calcium, methyl methacrylate butyl methacrylate-dimethylaminoethyl methacrylate copolymer and disintegrant and c) an outer taste masking layer surrounding the inner layer, said outer layer comprising methyl methacrylate butyl methacrylate-dimethylaminoethyl methacrylate copolymer.
Abstract translation: 一种适用于以喷洒剂型施用的多颗粒药物组合物，所述颗粒的直径小于2mm，并且包含a）惰性芯颗粒b）围绕所述惰性核心颗粒的内层，所述层包含阿托伐他汀钙，甲基丙烯酸甲酯 甲基丙烯酸酯 - 二甲基氨基乙基甲基丙烯酸酯共聚物和崩解剂，和c）围绕内层的外部掩蔽层，所述外层包含甲基丙烯酸甲酯 - 甲基丙烯酸丁酯 - 甲基丙烯酸二甲基氨基乙酯共聚物。
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公开(公告)号：WO2017056113A1
公开(公告)日：2017-04-06
申请号：PCT/IN2016/050330
申请日：2016-09-30
Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.
IPC: A61K31/7048 , A61K9/127
CPC classification number: A61K9/127 , A61K9/1277 , A61K31/7048
Abstract: The present invention relates to a process for the preparation of unilamellar liposomal composition of a polyene antibiotic drug, preferably amphotericin B. The process encompasses the steps of (a) mixing the polyene antibiotic and the phospholipid in an acidified organic solvent, (b) removing the organic solvent and (c) hydrating the dried complex with an aqueous buffer having a pH of 3 to 6.
Abstract translation: 本发明涉及一种制备多烯抗生素药物，优选两性霉素B的单层脂质体组合物的方法。该方法包括以下步骤：（a）在酸化的有机溶剂中混合多烯抗生素和磷脂，（b）除去 有机溶剂和（c）用pH为3至6的水性缓冲液使干燥的配合物水合。
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