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    참깨박 단백질을 포함하는 필름용 조성물 및 이의 제조방법
    53.
    发明授权
    참깨박 단백질을 포함하는 필름용 조성물 및 이의 제조방법 有权
    包含SESAME种子蛋白质的膜组合物及其生产方法

    公开(公告)号：KR101351226B1

    公开(公告)日：2014-01-13

    申请号：KR1020130017685

    申请日：2013-02-19

    Applicant: 충남대학교산학협력단

    Inventor： 송경빈 ,  송낙범 ,  조완신 ,  이지현 ,  배진주

    IPC: C08L89/00 ,  C08J5/18 ,  C08K5/07 ,  B65D65/38

    Abstract: The present invention relates to an edible film compound capable of be used in food packaging and the like and, more specifically, to a film composition comprising proteins extracted from sesame seed meal and a manufacturing method thereof. The edible film comprising the proteins extracted from sesame seed meal of the present invention is able to be used as a processed food packing material since tensile strength is 4.6 times higher than that of generally isolated soy proteins and permeability is 1.1 times lower than that of the generally isolated soy proteins. The edible film is able to reduce production costs in film manufacture by using low-priced sesame seed meal which is byproducts, is environment-friendly as compared to an existing plastic packing material and is able to be usefully used as a processed food packing material since the film is edible. Especially, the film of the present invention is able to be used as a packing material for meat processed foods which is closely related to fat oxidation due to light sine the film has an opaque color.

    Abstract translation: 本发明涉及能够用于食品包装等的可食用膜化合物，更具体地说，涉及由芝麻籽粉提取的蛋白质的膜组合物及其制造方法。 由本发明的芝麻籽粉提取的蛋白质可食用的薄膜能够作为加工食品包装材料使用，因为拉伸强度比通常分离的大豆蛋白的拉伸强度高4.6倍，并且渗透性比 一般分离的大豆蛋白。 可食用膜能够通过使用副产品的低价芝麻籽粉而降低制膜成本，与现有的塑料包装材料相比是环保型的，并且能够有效地用作加工食品包装材料，因为 这部电影是可食的。 特别地，本发明的膜能够用作肉加工食品的包装材料，其与光正弦的脂肪氧化密切相关，该膜具有不透明的颜色。

    스네일―ｐ５３ 간의 결합을 저해하는 화합물 및 이를 유효성분으로 함유하는 암질환 치료제
    55.
    发明公开
    스네일―ｐ５３ 간의 결합을 저해하는 화합물 및 이를 유효성분으로 함유하는 암질환 치료제 有权
    SNAIL-p53结合化学抑制剂和药物组合物治疗包含其中的癌性疾病

    公开(公告)号：KR1020120046129A

    公开(公告)日：2012-05-09

    申请号：KR1020120012619

    申请日：2012-02-08

    Applicant: 부산대학교 산학협력단 ,  충남대학교산학협력단

    Inventor： 박범준 ,  하남출 ,  이선혜 ,  송규용 ,  이지현

    IPC: G01N33/574 ,  G01N33/15

    CPC classification number: G01N33/5748 ,  A61K31/10 ,  A61K31/122 ,  C07C317/44 ,  C07C323/52 ,  C07C2602/10

    Abstract: PURPOSE: A compound which suppresses snail-p53 and a therapeutic agent for treating cancer are provided to induce p53 expression in K-ras mutant cell line and to effectively prevent or treat cancer. CONSTITUTION: A method for screening a therapeutic agent for treating K-ras mutagenic cancer comprises: a step of culturing snail and candidate drugs on a p53-fixed plate; a step of selecting a candidate drug which suppresses snail-p53 binding using ELISA reader. The therapeutic agent contains a compound which suppresses snail-p53 binding. A DNA binding domain specifically transfers a drug in K-ras mutant cells.

    Abstract translation: 目的：提供抑制snail-p53的化合物和治疗癌症的治疗剂，以诱导K-ras突变细胞系中的p53表达，并有效预防或治疗癌症。 构成：用于筛选治疗K-ras致突变性癌症的治疗剂的方法包括：在p53固定板上培养蜗牛和候选药物的步骤; 选择使用ELISA读数器抑制snail-p53结合的候选药物的步骤。 治疗剂含有抑制蜗牛p53结合的化合物。 DNA结合域特异性转移K-ras突变体细胞中的药物。

    신규한 흑삼의 추출물을 함유하는 약학조성물
    57.
    发明授权
    신규한 흑삼의 추출물을 함유하는 약학조성물 有权
    药物组合物，其包含新型黑参的提取物

    公开(公告)号：KR100781571B1

    公开(公告)日：2007-12-03

    申请号：KR1020070044633

    申请日：2007-05-08

    Applicant: 충남대학교산학협력단

    Inventor： 송규용 ,  신현중 ,  서영배 ,  이지현 ,  명창선 ,  오한진 ,  박용진

    IPC: A61K36/258 ,  A61P35/00

    Abstract: 본 발명은 인삼을 세척하여 적정 온도 및 시간으로 건조 및 증숙을 반복하는 공정을 통하여 기존의 구증구폭의 방법으로 제조된 흑삼에 비하여 시간이 단축되며, 대량생산이 가능한 항암활성을 갖는 흑삼을 제조하는 방법에 관한 것으로, 이로부터 제조된 흑삼 및 이의 추출물은 뛰어난 항암 효과를 나타내어 암질환의 예방 및 치료를 위한 조성물로 이용될 수 있다.
    흑삼, 대량생산, 수삼, 구증구폭, 항암

    신규한 흑삼의 추출물을 함유하는 약학조성물
    58.
    发明公开
    신규한 흑삼의 추출물을 함유하는 약학조성물 有权
    包含新型黑金刚提取物的药物组合物

    公开(公告)号：KR1020070111335A

    公开(公告)日：2007-11-21

    申请号：KR1020070044633

    申请日：2007-05-08

    Applicant: 충남대학교산학협력단

    Inventor： 송규용 ,  신현중 ,  서영배 ,  이지현 ,  명창선 ,  오한진 ,  박용진

    IPC: A61K36/258 ,  A61P35/00

    Abstract: A pharmaceutical composition comprising the extract of novel black ginseng is provided to reduce the preparation time, allow mass production of black ginseng and improve anticancer effects by increasing or identically maintaining the ginseng saponin content in black ginseng compared to the conventional preparation method(nine steaming nine drying method) of black ginseng. A pharmaceutical composition comprises 0.1-50 wt.% of the extract of novel black ginseng which is prepared by washing 4-6 year old fresh ginsengs and drying them at 35-55 deg.C for 20-28 hours, steaming the dried ginseng at 85-105 deg.C for 5-7 hours in a pot, drying the steamed ginseng at 50-70 deg.C for 9-15 hours, steaming the secondly dried ginseng at 95-125 deg.C for 5-7 hours, drying the secondly steamed ginseng for 12 hours, pulverizing the thirdly dried ginseng and storing the pulverized ginseng in water for 3-7 hours, and extracting the water-dipped pulverized ginseng with water, C1-C4 lower alcohol or a mixed solvent thereof.

    Abstract translation: 提供一种包含新型黑参提取物的药物组合物，以减少制备时间，通过增加或相同地维持黑参中人参皂甙含量，与常规制备方法相比，可以批量生产黑参，提高抗癌效果（九蒸九 干燥方法）黑参。 一种药物组合物包含0.1-50重量％的新黑参提取物，其通过洗涤4-6岁的新鲜人参并在35-55℃下干燥20-28小时，将干燥的人参蒸 85-105℃，5-7小时，在50-70℃干燥人参9-15小时，将第二次干燥的人参在95-125℃下蒸5〜7小时， 将第二次人参干燥12小时，粉碎第三次干参，将粉碎的人参储存在水中3-7小时，用水，C1-C4低级醇或其混合溶剂萃取水浸的人参。

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