公开(公告)号：NO964939A

公开(公告)日：1997-01-17

申请号：NO964939

申请日：1996-11-20

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG

IPC: A61K9/14 ,  A61K9/20 ,  B01J2/20

CPC classification number: A61K9/2013 ,  A61K9/146 ,  A61K9/2027 ,  A61K9/2095 ,  B01J2/20

公开(公告)号：HUT73657A

公开(公告)日：1996-09-30

申请号：HU9503296

申请日：1994-05-09

Applicant: BASF AG

Inventor： BINDER RUDOLF ,  GRABOWSKI SVEN ,  MUELLER WINFRIED ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/37 ,  A61K31/41 ,  A61K31/425 ,  A61K31/433 ,  A61K47/30 ,  A61K47/38

Abstract: PCT No. PCT/EP94/01489 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed May 9, 1994 PCT Pub. No. WO94/26267 PCT Pub. Date Nov. 24, 1994Compositions in the form of solid solutions containing a) 1-90% by weight of a coumarin derivative A from the group of alkoxycoumarins with a heterocyclic substituent or of hydroxycoumarins esterified with a sulfonic acid as active substance and b) 10-99% by weight of at least one water-soluble polymer B as carrier substance.

公开(公告)号：NO954660L

公开(公告)日：1995-11-17

申请号：NO954660

申请日：1995-11-17

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  MUELLER WINFRIED ,  ROSENBERG JOERG ,  BINDER RUDOLF ,  SANNER AXEL

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/37 ,  A61K31/41 ,  A61K31/425 ,  A61K31/433 ,  A61K47/30 ,  A61K47/38

Abstract: PCT No. PCT/EP94/01489 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed May 9, 1994 PCT Pub. No. WO94/26267 PCT Pub. Date Nov. 24, 1994Compositions in the form of solid solutions containing a) 1-90% by weight of a coumarin derivative A from the group of alkoxycoumarins with a heterocyclic substituent or of hydroxycoumarins esterified with a sulfonic acid as active substance and b) 10-99% by weight of at least one water-soluble polymer B as carrier substance.

公开(公告)号：FI955524A

公开(公告)日：1995-11-16

申请号：FI955524

申请日：1995-11-16

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  MUELLER WINFRIED ,  ROSENBERG JOERG ,  BINDER RUDOLF ,  SANNER AXEL

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/37 ,  A61K31/41 ,  A61K31/425 ,  A61K31/433 ,  A61K47/30 ,  A61K47/38 ,  A61K

Abstract: PCT No. PCT/EP94/01489 Sec. 371 Date Nov. 7, 1995 Sec. 102(e) Date Nov. 7, 1995 PCT Filed May 9, 1994 PCT Pub. No. WO94/26267 PCT Pub. Date Nov. 24, 1994Compositions in the form of solid solutions containing a) 1-90% by weight of a coumarin derivative A from the group of alkoxycoumarins with a heterocyclic substituent or of hydroxycoumarins esterified with a sulfonic acid as active substance and b) 10-99% by weight of at least one water-soluble polymer B as carrier substance.

公开(公告)号：MX9304658A

公开(公告)日：1994-02-28

申请号：MX9304658

申请日：1993-08-02

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  SANNER AXEL ,  ROSENBERG JOERG

IPC: A01N25/12 ,  A01N25/10 ,  A61K9/14 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A01N25/18

Abstract: Preparations in solid particle form containing active compounds, obtainable by intimate mixing of the active compound with a water-soluble melt of a) 10 to 90% by weight of a water-soluble polymer A of a viscosity Va of 1,000 to 120,000 cps and b) 10 to 90% by weight of a water-soluble polymer B of a viscosity Vb of 1 to 500 cps as a carrier substance, the viscosities Va and Vb being those of a 2% strength by weight aqueous solution at 20@C, measured by the capillary method ASTM D 2363-72 (European Pharmacopoeia, Vol. III, p. 37), and processing of the melt with shaping to give the particles.

公开(公告)号：BRPI0009299B1

公开(公告)日：2011-05-17

申请号：BRPI0009299

申请日：2000-03-17

Applicant: BASF AG

Inventor： LIEPOLD BERND ,  ROSENBERG JOERG ,  BERNDL GUNTHER ,  BREITENBACH JOERG

IPC: A61K47/10 ,  A61K9/16 ,  A61K9/20 ,  A61K47/14 ,  A61K47/34 ,  A61P31/10 ,  A61P35/00 ,  A61P37/06 ,  A61P43/00

Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.

公开(公告)号：CA2190882C

公开(公告)日：2007-01-16

申请号：CA2190882

申请日：1996-03-12

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K9/20 ,  A61K9/14 ,  A61K31/19 ,  B01J2/20

Abstract: A process for producing active agent preparations in the form of a solid sol ution of the active agent in a polymer matrix in which the active agent is melt-extruded in non-ionic form together with a polymer and a salt.

公开(公告)号：CA2208541C

公开(公告)日：2006-03-28

申请号：CA2208541

申请日：1995-12-22

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  GRABOWSKI SVEN ,  ROSENBERG JOERG ,  MAIER WERNER

IPC: A61J3/10 ,  A61J1/03 ,  A61J3/00 ,  A61K9/20 ,  B30B11/16 ,  B65B9/04

Abstract: The invention concerns a method of producing coated tablets by melt calendering, the melt containing the active substance being introduced into the forth cylinders between two films of the coating material.

公开(公告)号：DE50005515D1

公开(公告)日：2004-04-08

申请号：DE50005515

申请日：2000-03-17

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BERNDL GUNTHER ,  LIEPOLD BERND ,  BREITENBACH JOERG

IPC: A61K47/10 ,  A61K9/16 ,  A61K9/20 ,  A61K47/14 ,  A61K47/34 ,  A61P31/10 ,  A61P35/00 ,  A61P37/06 ,  A61P43/00

Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.

公开(公告)号：AT260647T

公开(公告)日：2004-03-15

申请号：AT00914147

申请日：2000-03-17

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BERNDL GUNTHER ,  LIEPOLD BERND ,  BREITENBACH JOERG

IPC: A61K47/10 ,  A61K9/16 ,  A61K9/20 ,  A61K47/14 ,  A61K47/34 ,  A61P31/10 ,  A61P35/00 ,  A61P37/06 ,  A61P43/00

Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.