公开(公告)号：SG50379A1

公开(公告)日：1998-07-20

申请号：SG1995002035

申请日：1993-12-10

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  BURKE RON ,  FAICT DIRK

IPC: A61K31/70 ,  A61K33/00 ,  A61K9/08 ,  A61K38/00 ,  A61K38/01 ,  A61K38/02 ,  A61K47/26 ,  A61K47/42 ,  A61M1/14 ,  A61M1/28 ,  A61P7/08 ,  A61K37/02

Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.

公开(公告)号：AT168010T

公开(公告)日：1998-07-15

申请号：AT94904432

申请日：1993-12-10

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  BURKE RON ,  FAICT DIRK

IPC: A61K9/08 ,  A61K31/70 ,  A61K33/00 ,  A61K38/00 ,  A61K38/01 ,  A61K38/02 ,  A61K47/26 ,  A61K47/42 ,  A61M1/14 ,  A61M1/28 ,  A61P7/08

Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.

公开(公告)号：AU689857B2

公开(公告)日：1998-04-09

申请号：AU1692695

申请日：1995-01-23

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  BURKE RON ,  SHOCKLEY TY ,  HENDERSON LEE W ,  FALLER BERNARDETTE

IPC: A61M1/14 ,  A61K31/715 ,  A61K33/14 ,  A61M1/28 ,  A61K47/36 ,  A61K47/12

Abstract: The method relates to providing an osmotic agent for a peritoneal dialysis solution containing sodium chloride and optionally lactate, bicarbonate, calcium and magnesium ions. The osmotic agent added comprises a first composition with a weight average molecular weight of ≥ 10,000 daltons and 0.25 to 2.0 (% w/v) of a second composition with a weight average molecular weight of ≤ 300 daltons.

公开(公告)号：AU1692695A

公开(公告)日：1995-08-08

申请号：AU1692695

申请日：1995-01-23

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  BURKE RON ,  SHOCKLEY TY ,  HENDERSON LEE W ,  FALLER BERNARDETTE

IPC: A61M1/14 ,  A61K31/715 ,  A61K33/14 ,  A61M1/28

Abstract: The method relates to providing an osmotic agent for a peritoneal dialysis solution containing sodium chloride and optionally lactate, bicarbonate, calcium and magnesium ions. The osmotic agent added comprises a first composition with a weight average molecular weight of ≥ 10,000 daltons and 0.25 to 2.0 (% w/v) of a second composition with a weight average molecular weight of ≤ 300 daltons.

公开(公告)号：AU5748894A

公开(公告)日：1994-07-19

申请号：AU5748894

申请日：1993-12-10

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  JONES MICHAEL R

IPC: A61K31/195 ,  A61K31/198 ,  A61K31/40 ,  A61K31/405 ,  A61K31/415 ,  A61K33/10 ,  A61K33/14 ,  A61M1/28 ,  A61P13/00 ,  A61P13/02 ,  A61P15/00 ,  A61K9/08

Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.

公开(公告)号：DE60030682T3

公开(公告)日：2018-03-29

申请号：DE60030682

申请日：2000-07-27

Applicant: BAXTER INT

Inventor： DUPONCHELLE ANNICK ,  FAICT DIRK ,  BALTEAU PATRICK ,  HARTMAN JEAN-PIERRE ,  MARTIS LEO ,  PELUSO FRANCESCO

IPC: A61J3/00 ,  A61K33/10 ,  A61J1/05 ,  A61J1/10 ,  A61J1/20 ,  A61K33/14 ,  A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61P13/12

公开(公告)号：ES2371532T3

公开(公告)日：2012-01-04

申请号：ES10075249

申请日：2002-10-01

Applicant: BAXTER INT

Inventor： MORTI STAVROULA ,  KAROOR SUJATHA ,  DONOVAN BRIAN ,  HAI TON THAT ,  KATADA MARI ,  LU LUIS ,  MARTIS LEO ,  MUJAIS SALIM ,  SANDERS PAUL ,  SOLTYS PAUL ,  TANDON RAHUL

IPC: A61M1/16 ,  A61M1/36 ,  A61M1/28 ,  B01D15/00 ,  B01J20/02 ,  B01J20/06 ,  B01J20/20 ,  B01J20/22 ,  B01J39/10 ,  B01J41/10

Abstract: Dispositivo (32) para eliminar las toxinas urémicas en un procedimiento de diálisis que comprende: un cuerpo (40) con una entrada (42) y una salida (44) y que define un interior, incluyendo el interior una capa que comprende ureasa, una capa que comprende óxido de zirconio, una capa que comprende fosfato de zirconio y una capa que comprende carbón; y el dispositivo (32) así construido y dispuesto para que un fluido que entra en el dispositivo (32) entre en contacto con la capa de fosfato de zirconio al entrar en el dispositivo antes de entrar en contacto con la capa de ureasa y antes de entrar en contacto con la capa de óxido de zirconio.

公开(公告)号：AT421997T

公开(公告)日：2009-02-15

申请号：AT05713781

申请日：2005-02-18

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： MARTIS LEO ,  PATEL MEHUL ,  GIERTYCH JOSEPH A ,  MONGOVEN JAMES W ,  KUNZLER JACQUELINE A ,  OWEN WILLIAM F

IPC: C12Q1/37 ,  C12Q1/04 ,  C12Q1/26 ,  G01N33/569

Abstract: Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.

公开(公告)号：SG145769A1

公开(公告)日：2008-09-29

申请号：SG2008062523

申请日：2005-02-18

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： MARTIS LEO ,  PATEL MEHUL ,  GIERTYCH JOSEPH A ,  MONGOVEN JAMES W ,  KUNZLER JACQUELINE A ,  OWEN WILLIAM F JR

IPC: C12Q1/04 ,  C12Q1/26 ,  C12Q1/37

Abstract: METHODS AND COMPOSITIONS FOR DETECTION OF MICROBIAL CONTAMINANTS IN PERITONEAL DIALYSIS SOLUTIONS Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. A novel cause of aseptic peritonitis is provided--aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.

公开(公告)号：AT398470T

公开(公告)日：2008-07-15

申请号：AT02768925

申请日：2002-10-01

Applicant: BAXTER INT

Inventor： KAROOR SUJATHA ,  DONOVAN BRIAN ,  HAI TON THAT ,  KATADA MARI ,  LU LUIS ,  MARTIS LEO ,  MORTI STAVROULA ,  MUJAIS SALIM ,  SANDERS PAUL ,  SOLTYS PAUL ,  TANDON RAHUL

IPC: A61M1/16 ,  A61M1/36 ,  A61M1/28 ,  A61M1/34 ,  B01D15/00 ,  B01J20/02 ,  B01J20/06 ,  B01J20/20 ,  B01J20/22 ,  B01J39/10 ,  B01J41/10

Abstract: The invention provides a device (32) for removing uremic toxins in a dialysis procedure comprising a body having an inlet (42) and an outlet (44) and defining an interior. The interior includes a layer comprising urease, a layer comprising zirconium oxide, a layer comprising zirconium phosphate, and a layer comprising carbon. The device is constructed and arranged so that a fluid entering the device contacts the zirconium phosphate layer before contacting the urease layer and before contacting the zirconium oxide layer.