公开(公告)号：DE102007011305A1

公开(公告)日：2008-09-11

申请号：DE102007011305

申请日：2007-03-06

Applicant: LEICA MICROSYSTEMS

Inventor： BIRK HOLGER ,  DYBA MARCUS ,  GUGEL HILMAR ,  SEYFRIED VOLKER

IPC: G02B27/62 ,  G02B21/00

公开(公告)号：DE102004032953B4

公开(公告)日：2008-02-07

申请号：DE102004032953

申请日：2004-07-07

Applicant: LEICA MICROSYSTEMS

Inventor： GUGEL HILMAR

IPC: G02B27/09 ,  G02B5/04 ,  G02B5/30 ,  G02B21/00 ,  G02B26/06

Abstract: The device causes a phase shift between first and second parts of a light beam and has first and second boundary surfaces (9,15). The first and second boundary surfaces reflect the first and second parts of the light beam respectively, whereby the first boundary surface is between first and second materials and the second is between the first material and a third material. Independent claims are also included for the following: (A) a raster microscope (B) and an optical device with a focusing optical arrangement.

公开(公告)号：DE60129920D1

公开(公告)日：2007-09-27

申请号：DE60129920

申请日：2001-12-11

Applicant: LEICA MICROSYSTEMS

Inventor： BEWERSDORF JOERG ,  GUGEL HILMAR

IPC: G02B21/06 ,  G02B21/34 ,  G02B21/00

公开(公告)号：DE102006009832A1

公开(公告)日：2007-09-06

申请号：DE102006009832

申请日：2006-03-01

Applicant: LEICA MICROSYSTEMS

Inventor： GUGEL HILMAR ,  DYBA MARCUS

IPC: G01N21/64 ,  G02B21/00

Abstract: The process involves concentrating an optical signal (4) simultaneously in multiple focal points. The focal points are focused in different sample places. The examined sample (1) covers a substance, which is transferred from one state to another state. The two states differ from each other in optical characteristics. The substance is brought in the sample area, which is detected by the former state and the latter state is induced by the optical signal. The pupil functions of the individual focal points are modulated. An independent claim is also included for a microscope, e.g. fluorescence laser scanning microscope.

公开(公告)号：DE102004032953A1

公开(公告)日：2006-02-02

申请号：DE102004032953

申请日：2004-07-07

Applicant: LEICA MICROSYSTEMS

Inventor： GUGEL HILMAR

IPC: G02B5/04 ,  G02B5/30 ,  G02B21/00 ,  G02B26/06 ,  G02B27/09

Abstract: The device causes a phase shift between first and second parts of a light beam and has first and second boundary surfaces (9,15). The first and second boundary surfaces reflect the first and second parts of the light beam respectively, whereby the first boundary surface is between first and second materials and the second is between the first material and a third material. Independent claims are also included for the following: (A) a raster microscope (B) and an optical device with a focusing optical arrangement.

公开(公告)号：DE10340964A1

公开(公告)日：2005-03-31

申请号：DE10340964

申请日：2003-09-05

Applicant: LEICA MICROSYSTEMS

Inventor： GUGEL HILMAR

IPC: G02B21/00 ,  G02F2/02 ,  G02B6/00 ,  G02B6/32 ,  G02B21/06 ,  G01N21/64

Abstract: The invention relates to a light source comprising a microstructured optical element (11) that receives and spectrally spreads the light from a primary light source (3). The inventive light source is characterized in that the spectrally spread light penetrates at least one other microstructured optical element (15, 19, 21). Said light source can be efficiently used in scanning microscopy and especially in STED microscopy.

公开(公告)号：GB2372897A

公开(公告)日：2002-09-04

申请号：GB0200165

申请日：2002-01-04

Applicant: LEICA MICROSYSTEMS

Inventor： GUGEL HILMAR ,  BEWERSDORF JOERG ,  HELL STEFAN W

IPC: G02B21/00 ,  G02B21/14

Abstract: A double confocal scanning microscope has an illuminating beam path (1) of a light source (2) and a detection beam path (3) of a detector (4). In order to eliminate at their cause the problems of reconstruction methods, at least one optical component (24, 25) acting on the illuminating and/or detection beam path (1, 3) is provided and is configured in such a way that it influences the amplitude and/or phase and/or polarization of the light, the characteristics of the light of the illumination and/or detection beam path thereby being able to be modified.

公开(公告)号：DE10107095A1

公开(公告)日：2002-08-29

申请号：DE10107095

申请日：2001-02-14

Applicant: LEICA MICROSYSTEMS

Inventor： BEWERSDORF JOERG ,  GUGEL HILMAR ,  HELL STEFAN W

IPC: G02B21/00 ,  G02B21/14

公开(公告)号：DE10046410A1

公开(公告)日：2002-03-28

申请号：DE10046410

申请日：2000-09-18

Applicant: LEICA MICROSYSTEMS

Inventor： BEWERSDORF JOERG ,  GUGEL HILMAR ,  HOFFMANN JUERGEN

IPC: G01N21/64 ,  G02B21/00 ,  G02B21/08 ,  G02B26/06 ,  G02B21/06 ,  G02B21/18