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公开(公告)号：ES2515195T3
公开(公告)日：2014-10-29
申请号：ES09775411
申请日：2009-11-30
Applicant: MEDTRONIC INC
Inventor： BENZ MICHAEL E , HOBOT CHRISTOPHER M , MCDONALD PHILLIP EDWARD , LUO LIAN L , KRAMER JOHN
IPC: A61K31/4168 , A61K9/00 , A61K9/22 , A61K31/445 , A61K47/34
Abstract: Un medicamento depot fluido que comprende: un poliéster poli(carbonato de trimetileno) biodegradable con grupos terminales protegidos con un alcohol primario; y un agente terapéutico que alivia el dolor post-operatorio seleccionado del grupo que consiste en bupivacaína o clonidina.
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52.发明专利
公开(公告)号：DE602004032427D1
公开(公告)日：2011-06-09
申请号：DE602004032427
申请日：2004-03-08
Applicant: MEDTRONIC INC
Inventor： STOKES KENNETH B , HOBOT CHRISTOPHER M , EBERT MICHAEL J
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公开(公告)号：CA2700586A1
公开(公告)日：2009-10-22
申请号：CA2700586
申请日：2009-04-17
Applicant: WARSAW ORTHOPEDIC INC , MEDTRONIC INC
Inventor： ZANELLA JOHN MYERS , KING VANJA MARGARETA , HOBOT CHRISTOPHER M , BIGGS DANIELLE , SHAW KATARA , MCDONALD PHILLIP EDWARD , MCKAY WILLIAM F , REMSEN KATHY L
IPC: A61K9/00 , A61K9/20 , A61K31/4162 , A61K47/34
Abstract: Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.
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公开(公告)号：CA2700578A1
公开(公告)日：2009-10-22
申请号：CA2700578
申请日：2009-04-17
Applicant: WARSAW ORTHOPEDIC INC , MEDTRONIC INC
Inventor： ZANELLA JOHN MYERS , KING VANJA MARGARETA , HOBOT CHRISTOPHER M , MCKAY WILLIAM F , HILDEBRAND KEITH R
IPC: A61K31/137 , A61K31/415 , A61K47/34 , A61P29/00
Abstract: Effective treatments of pain and/or inflammation from tendonitis, carpal tunnel syndrome, tarsal tunnel syndrome, osteoarthritis, bursitis and/or an oral-facial disease are provided. Through the administration of an effective amount of at least one alpha adrenergic agonist at or near a target site, one can reduce, prevent or treat pain and/or inflammation from tendonitis, carpal tunnel syndrome, tarsal tunnel syndrome, osteoarthritis, bursitis and/or an oral-facial disease.
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公开(公告)号：AU2009236419A1
公开(公告)日：2009-10-22
申请号：AU2009236419
申请日：2009-04-13
Applicant: MEDTRONIC INC , WARSAW ORTHOPEDIC INC
Inventor： KING VANJA MARGARETA , COX S MARK , MCKAY WILLIAM F , ZANELLA JOHN MYERS , REMSEN KATHY L , HOBOT CHRISTOPHER M
IPC: A61K9/00 , A61K31/573 , A61K47/34 , A61P29/00
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Patent Agency Ranking
公开(公告)号：DE60316579T2
公开(公告)日：2008-07-03
申请号：DE60316579
申请日：2003-08-13
Applicant: MEDTRONIC INC
Inventor： SPARER RANDALL V , HOBOT CHRISTOPHER M , LYU SUPING , DANG KIEM , CHENG PEIWEN
Abstract: The present invention provides active agent delivery systems for use in medical devices, wherein the active agent delivery systems include an active agent and a miscible polymer blend that includes a hydrophobic cellulose derivative and a polyvinyl homopolymer or copolymer selected from the group consisting of a polyvinyl alkylate homopolymer or copolymer, a polyvinyl alkyl ether homopolymer or copolymer, a polyvinyl acetal homopolymer or copolymer, and combinations thereof.
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公开(公告)号：DE60316579D1
公开(公告)日：2007-11-08
申请号：DE60316579
申请日：2003-08-13
Applicant: MEDTRONIC INC
Inventor： SPARER RANDALL V , HOBOT CHRISTOPHER M , LYU SUPING , DANG KIEM , CHENG PEIWEN
Abstract: The present invention provides active agent delivery systems for use in medical devices, wherein the active agent delivery systems include an active agent and a miscible polymer blend that includes a hydrophobic cellulose derivative and a polyvinyl homopolymer or copolymer selected from the group consisting of a polyvinyl alkylate homopolymer or copolymer, a polyvinyl alkyl ether homopolymer or copolymer, a polyvinyl acetal homopolymer or copolymer, and combinations thereof.
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58.发明专利
公开(公告)号：CA2535345A1
公开(公告)日：2005-03-03
申请号：CA2535345
申请日：2004-08-11
Applicant: MEDTRONIC INC
Inventor： SPARER RANDALL V , HOBOT CHRISTOPHER M , DINH THOMAS Q , DANG KIEM , LYU SUPING
IPC: A61L31/10 , A61F2/00 , A61F2/02 , A61F2/82 , A61K9/00 , A61L27/34 , A61L27/54 , A61L29/08 , A61L29/16 , A61L31/04 , A61L31/16
Abstract: An active agent delivery system that includes two or more active agents and two or more layers of polymers; wherein at least one layer includes miscible polymer blend comprising two or more miscible polymers; and further wherein delivery of at least one active agent occurs predominantly under permeation control.
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公开(公告)号：DE69333425T2
公开(公告)日：2004-12-02
申请号：DE69333425
申请日：1993-10-14
Applicant: MEDTRONIC INC
Inventor： JEVNE ALLAN H , BERGAN MATTHEW A , KEOGH JAMES R , HOBOT CHRISTOPHER M , EATON JOHN W
Abstract: The invention relates to articles having bioactive agents coupled to or repelled by a graft polymer which is in turn bonded to a polymeric substrate surface. The articles are useful as thromboresistant and/or antimicrobial medical devices.
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公开(公告)号：AU2003270705A1
公开(公告)日：2004-04-08
申请号：AU2003270705
申请日：2003-09-16
Applicant: MEDTRONIC INC
Inventor： DIDOMENICO EDWARD , SPARER RANDALL A , BENZ MICHAEL E , MILLER DAVID L , HOBOT CHRISTOPHER M , PEARSON DAVID A , TAPSAK MARK A
Abstract: Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.
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