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61.发明公开신규 〔＋〕－데쿠르신－구조이성체 합성 유도체〔ｄｅｃｕｒｓｉｎ－ｓｔｒｕｃｔｕｒａｌ ｉｓｏｍｅｒ ｓｙｎｔｈｅｓｉｓ ｄｅｒｉｖａｔｉｖｅ〕를 유효성분으로 포함하는 아토피성 피부염 질환의 치료 및 예방용 조성물 有权包含新型（+） - 去结构异构体合成衍生物用于治疗和预防原发性疾病的组合物
公开(公告)号：KR1020100116984A
公开(公告)日：2010-11-02
申请号：KR1020090035688
申请日：2009-04-23
Applicant: 충남대학교산학협력단
IPC: C07D493/04 , A61K31/35 , A61P37/00
Abstract: PURPOSE: A (+)-decursin-structural isomer synthetic derivative compound of novel structure is provided to suppress MCP-1, IL-16 and IL-18 secretion and to treat atopic dermatitis. CONSTITUTION: A (+)-decursin-structural isomer synthetic derivative compound of novel structure is denoted by general formula I or II. A pharmaceutical composition for preventing and treating atopic dermatitis contains (+)-decursin-structural isomer or pharmaceutically acceptable salt as an active ingredient. A health food for preventing and treating atopic dermatitis contains the (+)-decursin-structural isomer synthetic derivative compound or pharmaceutically acceptable salt as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule or beverage.
Abstract translation: 目的：提供新型结构的（+） - 前体结构异构体合成衍生物，以抑制MCP-1，IL-16和IL-18的分泌并治疗特应性皮炎。 构成：新型结构的（+） - 前衍生物 - 结构异构体合成衍生化合物由通式I或II表示。 用于预防和治疗特应性皮炎的药物组合物含有（+） - 前胡素结构异构体或药学上可接受的盐作为活性成分。 用于预防和治疗特应性皮炎的保健食品含有（+） - 前胶结构异构体合成衍生化合物或药学上可接受的盐作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊或饮料的形式使用。
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62.发明公开흑삼 가공 뿌리 추출물을 유효성분으로 함유하는 고병원성 조류 인플루엔자 바이러스의 예방 및 치료용 조성물 有权一种包含PANAX GINSENG加工提取物预防和治疗病原性AVIAN流感病毒的组合物
公开(公告)号：KR1020090073328A
公开(公告)日：2009-07-03
申请号：KR1020070141245
申请日：2007-12-31
Applicant: 충남대학교산학협력단
IPC: A61K36/258 , A61P31/16
Abstract: A composition for preventing and treating highly pathogenic avian influenza virus is provided to have suppression effect to highly pathogenic avian influenza virus by using an extract isolated from Panax ginseng. A method for producing a composition for preventing and treating highly pathogenic avian influenza virus comprises: a step of producing a Panax ginseng; a step of mixing the Panax ginseng with water in a mass ratio of 1:3-7, and maintaining at room temperature for 3-7 hours; a step of adding water containing purified water, low alcohol of C1-4, or their mixture solvent in a mass ratio of 1:5-20; a step of extracting for 2-8 hours one to five times; and a step of cooling, filtering and concentrating the extract.
Abstract translation: 本发明提供了用于预防和治疗高致病性禽流感病毒的组合物，通过使用从人参中分离出的提取物，对高致病性禽流感病毒具有抑制作用。 一种用于预防和治疗高致病性禽流感病毒的组合物的制备方法包括：生产人参的步骤; 将人参与水以1:3-7的质量比混合的步骤，并在室温下保持3-7小时; 以1：5-20的质量比添加含有纯水，C1-4的低级醇或其混合溶剂的水的步骤; 提取2-8小时1-5次; 以及冷却，过滤和浓缩提取物的步骤。
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公开(公告)号：KR1020180117298A
公开(公告)日：2018-10-29
申请号：KR1020170050222
申请日：2017-04-19
Applicant: 경북대학교 산학협력단 , 충남대학교산학협력단
IPC: A61K31/352 , A61K31/353 , A61K31/37
CPC classification number: A61K31/352 , A61K31/353 , A61K31/37
Abstract: 본발명은시토크롬 P450 동효소억제용조성물에관한것으로, 본발명의일 실시예에개시된화합물을이용하면시토크롬 450 2B6, 시토크롬 450 2C8, 시토크롬 450 2C9, 시토크롬 450 2D6 및시토크롬 450 2J2의활성을효과적으로저해할수 있다.
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公开(公告)号：KR101733477B1
公开(公告)日：2017-05-11
申请号：KR1020160040269
申请日：2016-04-01
Applicant: 충남대학교산학협력단
Abstract: 본발명은종래치료제의부작용이나약물내성을유발하지않고, 독성이낮아장기투여가가능한전립선질환의예방및 치료/증상개선용조성물에관한것으로, 보다상세하게는합환피추출물을유효성분으로함유하는것을특징으로하는전립선질환의예방및 치료/증상개선용조성물에관한것이다.
Abstract translation: 本发明涉及用于前列腺疾病的预防和治疗/症状改善的组合物，其可以由于低毒性而长期施用而不会引起常规治疗剂的不利副作用或耐药性，更具体地， 本发明涉及用于前列腺疾病的预防和治疗/症状改善的组合物。
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公开(公告)号：KR101730940B1
公开(公告)日：2017-04-27
申请号：KR1020160021163
申请日：2016-02-23
Applicant: 충남대학교산학협력단
Abstract: 본발명은받침대와분배기능을갖는팝콘용기세트에관한것으로, 더상세하게는원통형의팝콘용기하부에양측으로배출공을형성하고, 팝콘용기를고정시킨받침대는중앙에팝콘용기를안치하는안치홈이형성되고, 안치홈양측으로접시홈을각각형성하여팝콘용기의배출공으로배출된팝콘을임시보관하도록함으로서두 명이팝콘을먹을때에팔 동선이서로겹치는것을방지하면서팝콘용기의팝콘저장량이줄어도쉽게먹을수 있도록하는받침대와분배기능을갖는팝콘용기세트에관한것이다.
Abstract translation: 本发明涉及到爆米花容器设置具有基部和一个分布函数，并且更具体地，形成在筒状的基座的爆米花的容器下部的两侧上的排气孔具有固定爆米花容器放置到放置爆米花容器到中央槽 发育不良是，由所述家庭侧所载形成的家的板，每个起草排出爆米花爆米花球的排出容器容易甚至两个人同时防止臂铜重叠时，他们吃爆米花，爆米花减少爆米花的储存容器的量 爆米花容器组具有用于分配食物和分配功能的基座。
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Patent Agency Ranking
公开(公告)号：KR101718355B1
公开(公告)日：2017-03-21
申请号：KR1020150152484
申请日：2015-10-30
Applicant: 충남대학교산학협력단
IPC: A61K31/704 , A61K9/14 , A61K9/20 , A61K9/48 , A23L1/30
Abstract: 본발명은진세노사이드 Rg6, Rg4, Rh4 및 Rk3를유효성분으로포함하는고혈압또는당뇨병성족부궤양의예방또는치료용조성물에관한것으로, 상기진세노사이드 Rg6, Rg4, Rh4 및 Rk3는혈관이완효과가우수하여, 혈류공급을원활하게하므로고혈압또는당뇨병성족부궤양을예방또는치료할수 있는조성물로서유용하게사용될수 있다.
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公开(公告)号：KR1020160094802A
公开(公告)日：2016-08-10
申请号：KR1020150016300
申请日：2015-02-02
Applicant: 충남대학교산학협력단
IPC: A61K31/403 , A61K31/17
CPC classification number: A61K31/403 , A61K31/17
Abstract: 본발명은카바졸유레아유도체를함유하는혈관질환의예방또는치료용조성물에관한것으로서, 상기카바졸유레아유도체는혈소판응집억제효과와생체내 안정성이매우우수하여혈관질환의예방또는치료용의약조성물로용이하게이용가능하다.
Abstract translation: 本发明涉及含有咔唑脲衍生物的预防或治疗血管病的组合物。 根据本发明，咔唑脲衍生物可防止血小板聚集，体内稳定性优异。 因此，本发明的组合物可以容易地用作预防或治疗血管疾病的药物组合物。
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68.发明授权엔테로코커스 패칼리스 시알엔비-에이3을 이용한 발효인삼의 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물 有权包含使用粪肠球菌CRNB-A3的发酵人参提取物用于治疗或预防特应性皮炎的组合物
公开(公告)号：KR101418748B1
公开(公告)日：2014-07-11
申请号：KR1020120045102
申请日：2012-04-30
Applicant: 충남대학교산학협력단
IPC: A61K36/258 , A61K35/747 , A23L1/30 , A23L19/00
Abstract: 본 발명은 엔테로코커스 패칼리스 CRNB-A3(
Enterococcus faecalis CRNB-A3, 미생물 수탁번호 : KCTC11930BP)을 이용한 발효인삼의 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물에 관한 것이다. 상기 조성물은 MCP-1(monocyte chemoattractant protein-1), IL-8(interleukin-8) 및 IL-6(interleukin-6)의 활성을 억제하는 효과가 탁월하여 아토피 피부염과 같은 각종 피부질환의 증세를 치료 또는 경감시키는 치료제로 이용될 수 있다.-
69.发明授权신규한 패니바실러스 속 엠비티213 균주, 이를 이용한 발효인삼 및 이를 이용한 발효인삼 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물 有权新款PAENIBACILLUS SP。 MBT213，使用其的发明金山和包含用于预防或治疗原生质体的发酵金山提取物的组合物
公开(公告)号：KR101345226B1
公开(公告)日：2013-12-26
申请号：KR1020130090695
申请日：2013-07-31
Applicant: 충남대학교산학협력단
IPC: C12N1/20 , A23L19/00 , A23L33/00 , A61K36/258
Abstract: The present invention relates to novel Paenibacillussp. MBT213 (microorganism deposition number KACC91831P) and to a fermented ginseng using the same. In addition, the present invention relates to a composition for preventing or treating atopic dermatitis which comprises extracts of fermented ginseng using Paenibacillussp. MBT213. A culture media of the Paenibacillussp. MBT213 (microorganism deposition number KACC91831P) has excellent effects which converts ginsenoside Rg1 inside the ginseng into Rd. In addition, the fermented ginseng or extract of the same which is manufactured by using the effects suppresses activities of MIP-1α (macrophage inflammatory protein-1α), IL-4 (interleukin-4) and IL-13 (interleukin-13) in order to be used as a medicine for treating or alleviating symptoms of various skin diseases such as atopic dermatitis.
Abstract translation: 本发明涉及新型Paenibacillussp。 MBT213（微生物保藏号KACC91831P）和使用其的发酵人参。 此外，本发明涉及一种用于预防或治疗特应性皮炎的组合物，其包含使用Paenibacillussp的发酵人参提取物。 MBT213。 Paenibacillussp的文化媒体。 MBT213（微生物保藏号KACC91831P）具有将人参中人参皂苷Rg1转化为Rd的优异效果。 此外，通过使用该效果制造的发酵人参或其提取物抑制MIP-1α（巨噬细胞炎症蛋白-1α），IL-4（白细胞介素-4）和IL-13（白细胞介素-13）的活性 用作治疗或减轻诸如特应性皮炎等各种皮肤病症状的药物。
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公开(公告)号：KR1020130026081A
公开(公告)日：2013-03-13
申请号：KR1020110089469
申请日：2011-09-05
Applicant: 충남대학교산학협력단
IPC: A61K31/403 , A61P9/12 , A61P9/10 , A61P9/00
CPC classification number: A61K31/404 , Y10S514/822 , Y10S514/824
Abstract: PURPOSE: A composition containing a murrayafoline A derivative is provided to suppress platelet aggregation, and to prevent or treat vascular diseases. CONSTITUTION: A composition for preventing or treating vascular diseases contains a compound of chemical formula 1. In chemical formula 1, R1 is independently selected among hydrogen, C1-C6 alkyl, formyl, C1-C6 alkylester, and carboxylic acid; R2 is independently selected among hydrogen, hydroxy, C1-C6 alkyl, or C1-C6 alkyloxy; and R4 is independently selected from hydrogen, C1-C6 alkyl, C2-C6 alkenyl, or C1-C6 alkylketone.
Abstract translation: 目的：提供含有药物衍生物衍生物的组合物，以抑制血小板聚集，并预防或治疗血管疾病。 构成：用于预防或治疗血管疾病的组合物含有化学式1的化合物。在化学式1中，R 1独立地选自氢，C 1 -C 6烷基，甲酰基，C 1 -C 6烷基酯和羧酸; R2独立地选自氢，羟基，C1-C6烷基或C1-C6烷氧基; 和R 4独立地选自氢，C 1 -C 6烷基，C 2 -C 6烯基或C 1 -C 6烷基酮。
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