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公开(公告)号：CA2682356A1
公开(公告)日：2008-10-30
申请号：CA2682356
申请日：2008-04-16
Applicant: ABBOTT LAB
Inventor： PARK CHEOL-MIN , WENDT MICHAEL D , WANG XILU , KUNZER AARON R , HASVOLD LISA A , WANG LE , TAO ZHI-FU , SONG XIAOHONG , ELMORE STEVEN W , SOUERS ANDREW J , BRUNCKO MILAN
IPC: C07D209/34 , A61K31/404 , A61P35/00 , C07D401/12 , C07D413/06 , C07D417/04
Abstract: Compounds of formula (I) which inhibit the activity of anti-apoptotic McI -I protein, compositions containing the compounds, and methods of treating d iseases involving overexpressed or unregulated McI-I protein are disclosed.
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公开(公告)号：DE60316128T2
公开(公告)日：2008-05-29
申请号：DE60316128
申请日：2003-03-14
Applicant: ABBOTT LAB
Inventor： ELMORE STEVEN W , PARK CHEOL-MIN , WANG XILU
IPC: C07D295/20 , A61K31/4418 , A61K31/4422 , A61K31/495 , A61K31/5377 , A61P25/18 , A61P29/00 , A61P31/12 , A61P31/18 , A61P35/00 , A61P37/06 , A61P43/00 , C07D211/16 , C07D211/18 , C07D211/26 , C07D211/58 , C07D211/82 , C07D211/90 , C07D295/215
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公开(公告)号：MX2007014049A
公开(公告)日：2008-02-11
申请号：MX2007014049
申请日：2006-05-12
Applicant: ABBOTT LAB
Inventor： BRUNCKO MILAN , KUNZER AARON R , LYNCH CHRISTOPHER L , WANG XILU , DING HONG , ELMORE STEVEN W , MCCELLAN WILLIAM J , PARK CHEOL MIN , SONG XIAHONG
IPC: C07D295/14 , A61K31/496 , A61P35/00 , C07D487/08 , C07D491/08
Abstract: Se describen compuestos que inhiben la actividad de miembros de proteina de familia anti-apoptotica, composiciones que contienen los compuestos y metodos para tratar enfermedades durante las cuales ocurre la expresion de uno o mas miembros de proteina de familia anti-apoptotica.
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公开(公告)号：PL193323B1
公开(公告)日：2007-02-28
申请号：PL34301899
申请日：1999-02-12
Applicant: ABBOTT LAB , LIGAND PHARM INC
Inventor： COUGHLAN MICHAEL J , ELMORE STEVEN W , KORT MICHAEL E , KYM PHILIP R , MOORE JIMMIE L , PRATT JOHN K , WANG ALAN X , EDWARDS JAMES P , JONES TODD K
IPC: C07D491/04 , C07D491/052 , A61K31/44 , A61K31/4738 , A61K31/505 , A61K31/519 , A61P29/00
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公开(公告)号：BR0010728A
公开(公告)日：2004-02-17
申请号：BR0010728
申请日：2000-11-06
Applicant: ABBOTT LAB
Inventor： ELMORE STEVEN W , COOPER CURT S , SCHULTZ COLLEEN C , HUTCHINSON DOUGLAS K , DONNER PAMELA L , GREEN BRIAN E , ANDERSON DAVID D , XIE QUINGHUA , DINGES JURGEN , LYNCH LINDA M
IPC: A61K31/4375 , A61K31/4436 , A61K31/444 , A61K31/4725 , A61K31/496 , A61K31/542 , A61P31/04 , A61P43/00 , C07B61/00 , C07D405/04 , C07D409/04 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07D513/04 , C07D519/00 , C07D409/00
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Patent Agency Ranking
公开(公告)号：SI1053239T1
公开(公告)日：2003-12-31
申请号：SI9930243
申请日：1999-02-12
Applicant: ABBOTT LAB , LIGAND PHARM INC
Inventor： COUGHLAN MICHAEL J , ELMORE STEVEN W , KORT MICHAEL E , KYM PHILIP R , MOORE JIMMIE L , PRATT JOHN K , WANG ALAN X , EDWARDS JAMES P , JONES TODD K
IPC: A61K31/44 , A61K31/505 , C07D491/04
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公开(公告)号：AU7019401A
公开(公告)日：2002-01-14
申请号：AU7019401
申请日：2001-06-27
Applicant: ABBOTT LAB , LIGAND PHARM INC
Inventor： COGHLAN MICHAEL J , EDWARDS JAMES P , ELMORE STEVEN W , JONES TODD K , KORT MICHAEL E , KYM PHILIP R , MOORE JIMMIE L , PRATT JOHN K , WANG ALAN X
IPC: C07D491/052 , A61K31/4741 , A61K31/519 , A61K31/5377 , A61P29/00 , A61P37/00 , A61P43/00 , C07D491/04 , A61K31/435
Abstract: Compounds having Formula I are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula I and methods of inhibiting immune or autoimmune diseases in a mammal.
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公开(公告)号：BR9907788A
公开(公告)日：2001-10-30
申请号：BR9907788
申请日：1999-02-12
Applicant: ABBOTT LAB , LIGAND PHARM INC
Inventor： COUGHLAN MICHAEL J , ELMORE STEVEN W , KORT MICHAEL E , KYM PHILIP R , MOORE JIMMIE L , PRATT JOHN K , WANG ALAN X , EDWARDS JAMES P , JONES TODD K
IPC: C07D491/052 , A61K31/4738 , A61K31/519 , A61P29/00 , C07D491/04 , A61K31/44 , A61K31/505
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公开(公告)号：HK1033308A1
公开(公告)日：2001-08-24
申请号：HK01102793
申请日：2001-04-19
Applicant: ABBOTT LAB CHAD , LIGAND PHARM INC
Inventor： COUGHLAN MICHAEL J , ELMORE STEVEN W , KORT MICHAEL E , KYM PHILIP R , MOORE JIMMIE L , PRATT JOHN K , WANG ALAN X , EDWARDS JAMES P , JONES TODD K
IPC: C07D491/052 , A61K31/4738 , A61K31/519 , A61P29/00 , C07D491/04 , C07D , A61K
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公开(公告)号：PL343018A1
公开(公告)日：2001-07-30
申请号：PL34301899
申请日：1999-02-12
Applicant: ABBOTT LAB , LIGAND PHARM INC
Inventor： COUGHLAN MICHAEL J , ELMORE STEVEN W , KORT MICHAEL E , KYM PHILIP R , MOORE JIMMIE L , PRATT JOHN K , WANG ALAN X , EDWARDS JAMES P , JONES TODD K
IPC: C07D491/052 , A61K31/4738 , A61K31/519 , A61P29/00 , C07D491/04 , A61K31/44
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