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103 records (took 0.022 seconds)

    61.
    发明专利
    未知

    公开(公告)号：BRPI0508219A

    公开(公告)日：2007-07-17

    申请号：BRPI0508219

    申请日：2005-02-18

    Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

    Inventor： MARTIS LEO ,  PATEL MEHUL ,  GIERTYCH JOSEPH A ,  MONGOVEN JAMES W ,  KUNZLER JACQUELINE A ,  OWEN WILLIAM F JR

    IPC: C12Q1/37 ,  C12Q1/04 ,  C12Q1/26

    Abstract: Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.

    BIOCOMPATIBLE DIALYSIS FLUIDS CONTAINING ICODEXTRINS
    63.
    发明专利
    BIOCOMPATIBLE DIALYSIS FLUIDS CONTAINING ICODEXTRINS 未知

    公开(公告)号：HK1088535A1

    公开(公告)日：2006-11-10

    申请号：HK06108881

    申请日：2006-08-10

    Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

    Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

    IPC: A61K20060101 ,  A61K31/718 ,  A61K31/724 ,  A61M20060101 ,  A61M1/28

    Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

    BIOCOMPATIBLE DIALYSIS FLUIDS CONTAINING ICODEXTRINS
    66.
    发明专利
    BIOCOMPATIBLE DIALYSIS FLUIDS CONTAINING ICODEXTRINS 未知

    公开(公告)号：AU2003299683A1

    公开(公告)日：2004-07-22

    申请号：AU2003299683

    申请日：2003-12-18

    Applicant: BAXTER INT

    Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

    IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

    Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

    68.
    发明专利
    未知

    公开(公告)号：DE69527923D1

    公开(公告)日：2002-10-02

    申请号：DE69527923

    申请日：1995-05-25

    Applicant: BAXTER INT

    Inventor： MARTIS LEO ,  HENDERSON W

    IPC: A61K9/08 ,  A61K31/19 ,  A61K31/194 ,  A61K31/70 ,  A61K31/7004 ,  A61K33/00 ,  A61K33/10 ,  A61K33/14 ,  A61M1/28 ,  A61P7/08 ,  A61P13/12 ,  A61M1/16

    Abstract: A peritoneal dialysis solution that is biochemically balanced to correct metabolic acidosis associated with chronic renal failure in a more physiological manner. The peritoneal dialysis solution has a physiological pH, e.g. pH of 70 to 74 and contains bicarbonate at a concentration that is found in normal blood. Additionally, the solution contains carbon dioxide at a partial pressure that is similar to partial pressure of carbon dioxide found in normal blood. The peritoneal dialysis solution also contains a weak acid with a pKa of less than 5.0.

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