公开(公告)号：EP0540966B1

公开(公告)日：1997-02-12

申请号：EP92118251.5

申请日：1992-10-26

Applicant: Hewlett-Packard Company

Inventor： Wildnauer, Kenneth Richards ,  Stimple, James Roy ,  Knight, John Douglas ,  West, Joseph N. ,  Broome, Barry G.

IPC: G01J3/18 ,  G01J3/28

CPC classification number: G01J3/18 ,  G01J3/0221 ,  G01J3/2889 ,  G01J2003/062 ,  G01J2003/069 ,  G01J2003/1819 ,  G01J2003/1828

公开(公告)号：EP0089472A1

公开(公告)日：1983-09-28

申请号：EP83100911.3

申请日：1983-02-01

Applicant: International Business Machines Corporation

Inventor： Bjorklund, Gary Carl ,  Hunziker, Heinrich Erwin

IPC: G01J3/28

CPC classification number: G01J3/2889 ,  G11C13/02

Abstract: A method for the spectral analysis of short optical pulses (12) uses an optical group velocity dispersive medium (14), for example, a low loss single mode optical fiber, to map the optical spectrum (a) of the pulse into the time domain (c, d). One application of this method is used for obtaining a serial, time domain readout of information stored in a photochemical hole burning memory which utilizes a medium with broad hole widths.

Abstract translation: 用于短光脉冲（12）的光谱分析的方法使用光群速度色散介质（14），例如低损耗单模光纤，将脉冲的光谱（a）映射到时域 （c，d）。 该方法的一个应用是用于获得存储在光化学孔燃烧存储器中的信息的串行时域读出，该存储器利用具有宽孔宽度的介质。

公开(公告)号：EP2340429A4

公开(公告)日：2017-12-20

申请号：EP09821224

申请日：2009-10-14

Applicant: TISSUEVISION INC

Inventor： RAGAN TIMOTHY MICHAEL ,  SUTIN JASON DOUGLAS-BART

IPC: G01N21/17 ,  G01J3/28 ,  G01N1/00 ,  G01N21/27 ,  G01N21/62

CPC classification number: G01N21/6408 ,  G01J3/2803 ,  G01J3/2889 ,  G01J3/4406 ,  G01N2021/653

Abstract: The subject invention discloses devices and methods for sampling an analog signal in order to perform data analysis. More particularly, the subject invention provides a time-resolved, direct, high-speed sampling of analog output of a detector, in order to capture harmonic content of the signal without the need to modulate the detection system. The sampling devices and corresponding methods include a detector module for measuring a response generated from a sample, an analog to digital converter for sampling the analog signal, received from the detector module, and converting it into a digital signal; and a logic circuit coupled to the converter for processing the digital signal. The sampling rate of the converter is faster than the response of the sample, and the logic circuit is capable of analyzing the digital signal acquired from the converter and continuously transferring the data analysis obtained to a storage or display device.

公开(公告)号：EP2609407A4

公开(公告)日：2017-12-13

申请号：EP11819225

申请日：2011-08-19

Applicant: HONEYWELL ASCA INC

Inventor： MOUSAVI PAYAM ,  DODGE STEVEN ,  HARAN FRANK MARTIN ,  SAVARD STÉPHANE ,  JEZ DAVID ,  HEATH STUART JAMES

IPC: G01N21/3586 ,  D21F7/00 ,  D21F7/06 ,  D21G9/00 ,  G01B11/06 ,  G01J3/28 ,  G01J3/42 ,  G01N21/3559 ,  G01N21/86

CPC classification number: G01J3/42 ,  D21F7/06 ,  D21G9/0009 ,  G01B11/0625 ,  G01J3/28 ,  G01J3/2889 ,  G01N21/3559 ,  G01N21/3586 ,  G01N2021/8663

Abstract: An apparatus for incorporation into time-domain spectroscopy systems that creates a continuous reference whereby a sample pulses' phase and amplitude can be tracked and corrected employs a beam splitter to generate sample and reference pulses. A detector is positioned for receiving the reference radiation pulses that do not interact with the sample. The same detector is also positioned for receiving the sample radiation pulses that emerge from the sample. The apparatus can be readily implemented by being configured between the emitter and detector of a terahertz time-domain spectrometer. The reference pulse is used to trace the changes in time and amplitude of the sample pulse. Since any changes in the reference pulse will most likely manifest in the sample pulse, the reference pulse is monitored and used to correct the sample pulse and thereby reduce the effects of jitter.

公开(公告)号：EP3213683A1

公开(公告)日：2017-09-06

申请号：EP14904835.7

申请日：2014-11-14

Applicant: Korea Advanced Institute of Science and Technology

Inventor： BAE, Hyeon Min ,  CHOI, Jong Kwan ,  CHOI, Min Gyu ,  KIM, Jae Myoung ,  HWANG, Gun Pil

IPC: A61B5/1455 ,  G01N21/25 ,  G01J3/28

CPC classification number: A61B5/725 ,  A61B5/0075 ,  A61B5/14546 ,  A61B5/14553 ,  A61B5/7225 ,  G01J3/027 ,  G01J3/108 ,  G01J3/28 ,  G01J3/2889 ,  G01J2003/102 ,  G01N21/25 ,  G01N21/359 ,  G01N2201/06113 ,  G01N2201/062

Abstract: Disclosed are an optical spectroscopy system using a matched filter-based broadband signal receiver for stable data extraction, and a method for controlling the optical spectroscopy system. The optical spectroscopy system may comprise: a light transmission unit for irradiating light on a particular region of a subject by means of a plurality of light sources, wherein the light irradiated from the plurality of light sources is code-modulated by means of the Walsh codes and then irradiated; and a light receiving unit for detecting emergent light which has passed through the particular region, wherein the light source is identified by demodulating the light by means of the Walsh codes.

Abstract translation: 公开了一种使用匹配的基于滤波器的宽带信号接收器用于稳定数据提取的光学光谱系统，以及用于控制光学光谱系统的方法。 光学光谱系统可以包括：光传输单元，用于借助多个光源将光照射在对象的特定区域上，其中从多个光源照射的光通过沃尔什码进行码调制 然后照射; 以及用于检测已经穿过特定区域的出射光的光接收单元，其中通过利用沃尔什码解调光来识别光源。

公开(公告)号：EP2761276A1

公开(公告)日：2014-08-06

申请号：EP12778605.1

申请日：2012-09-20

Applicant: Carl Zeiss Microscopy GmbH

Inventor： MÖHLER, Gunter ,  SCHMIDT, Dietmar ,  HOLUB, Oliver ,  HAUSCHILD, Robert

IPC: G01N21/64 ,  G02B21/00 ,  G01J3/28 ,  G01J3/44

CPC classification number: G01N21/64 ,  G01J1/44 ,  G01J3/2889 ,  G01J3/44 ,  G01N21/6408 ,  G01N21/6458 ,  G02B21/0076 ,  G02B21/0084

Abstract: 1. An evaluation circuit for an optoelectronic detector and method for recording fluorescence events. 2.1 In fluorescence measurements and measurements of the Raman spectrum using pulsed stimulation, spectrally overlapping stray light and fluorescent light interfere with each other, reducing the sensitivity of the measurements. With known evaluation circuits (1), which provide synchronisation of an analogue/digital converter (2) with the light pulses, it is only possible for fluorescent light to be absorbed, or else fluorescent and stray light cannot be differentiated. An improved evaluation circuit (1) is required that provides high sensitivity for low expense. 2.2 For this purpose, a shift register (3) having at least one data input, one clock input, a plurality of register stages and at least one data output is provided, wherein the output from the analogue/digital converter (2) is connected to the data input to the shift register (3). With a shift register, fluorescent and stray light can be differentiated temporally at low expense. 2.3 Microscopy

公开(公告)号：EP2284513A1

公开(公告)日：2011-02-16

申请号：EP09754578.4

申请日：2009-05-14

Applicant: Nippon Telegraph and Telephone Corporation

Inventor： ITO, Fumihiko ,  OKAMOTO, Keiji

IPC: G01J11/00 ,  G01J3/28

CPC classification number: G01J3/2889 ,  G01J11/00 ,  H04J14/0221

Abstract: Light to be measured L and sampling pulse light L SP are each split into M beams, and a time delay of 0, T, 2T, ..., (M-1)T is given to each of the M-split sampling pulse light beams. The M-split light beams to be measured are then respectively multiplexed with M optical 90-degree hybrids, and M electrical field amplitudes per time T are determined for the light beam to be measured, based on M sets of output currents received at a balance light receiving element that receives light emitted from each of the optical 90-degree hybrids. The amplitudes of the respective wavelength optical signals contained in the light beam to be measured are calculated through Fourier transformations of the field electrical amplitudes. Pulsed light with a spectral width that covers the total frequency bandwidth of the light to be measured is used as the sampling pulse light. Where the total frequency bandwidth of the light to be measured is Δf total , and the frequency interval of the optical signals contained in the light to be measured is Δf, T ≤ 1/Δf total and 1/(met) ≤ Δf are set.

Abstract translation: 将要测量的光L和采样脉冲光LSP分别分成M个光束，并且将0时间延迟T，2T，...，（M-1）T给予每个M分割采样脉冲光 梁。 然后，将要测量的M分割光束分别与M个光学90度混合器复用，并且基于在平衡处接收的M组输出电流，针对要测量的光束确定每时间T的M个电场振幅 光接收元件，接收从每个光学90度混合器发射的光。 通过场电振幅的傅里叶变换来计算待测光束中包含的各个波长光信号的振幅。 使用具有覆盖要测量的光的总频率带宽的光谱宽度的脉冲光作为采样脉冲光。 在被测光的总频带宽度为Δftotal，被测定光中包含的光信号的频率间隔为Δf的情况下，设定T≤1/Δftotal，1 /（met）≤Δf。

公开(公告)号：EP2250473A1

公开(公告)日：2010-11-17

申请号：EP09716330.7

申请日：2009-02-21

Applicant: Carl Zeiss MicroImaging GmbH

Inventor： CORRENS, Nico

IPC: G01J3/28 ,  G01N21/64

CPC classification number: G01J3/2889 ,  G01J9/00 ,  G01J2003/282

Abstract: The present invention relates to a solution for time-resolved spectroscopy, wherein the sample to be analyzed is illuminated by a modulated light source, and the spectrum reflected therefrom is recorded in a time-resolved manner and evaluated. In the method according to the invention for time-resolved spectroscopy, a sample to be analyzed is irradiated by a modulated light source having short light pulses, and the radiation emitted by the sample is represented via imaging optical elements and a spectral-selective element on a sensor disposed in the image plane, and the signals thereof are evaluated by a control and regulating unit, and/or stored. The sensor disposed in the image plane is a PMD sensor, which in addition to the intensity values also determines the running times of the radiation emitted by the sample, and forwards the same to the control and regulating unit. Although PMD sensors were originally intended for object recognition, particularly in traffic, the use thereof in many other technical fields is conceivable and advantageous. The solution provided herein describes the use of PMD sensors in spectroscopy, particularly for the time-resolved analysis of samples. However, the use of PMD sensors is also possible in Raman spectrometry, or for the measurement of luminescence, such as for differentiating phosphorescence and fluorescence light.

公开(公告)号：EP1317852A4

公开(公告)日：2009-07-22

申请号：EP01970583

申请日：2001-08-24

Applicant: AMNIS CORP

Inventor： BASIJI DAVID ,  ORTYN WILLIAM

IPC: G01N21/64 ,  G01N15/00 ,  G01N15/02 ,  G01N15/14 ,  G01N21/27 ,  G06K9/00 ,  H04N5/232

CPC classification number: G06K9/00127 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0232 ,  G01J3/14 ,  G01J3/2823 ,  G01J3/2889 ,  G01N15/14 ,  G01N21/6458 ,  G01N2015/1497

Abstract: Light from an object (152) moving through an imaging system (154) is collected, dispersed, and imaged onto a time delay integration (TDI) detector (148) that is inclined relative to an axis of motion of the object, producing a pixilated output signal. In one embodiment, the movement of the image object over the TDI detector (148) is asynchronous with the movement of the output signal producing an output signal that is a composite of the image of the object at varying focal point along the focal plane. In another embodiment, light from the object is periodically incident on the inclined TDI, producing a plurality of spaced apart images and corresponding output signals that propagate across the TDI detector (148). The inclined plane enables images of FISH probes or other components within an object to be produced at different focal point, so that the 3D spatial relationship between the FISH probes or components can be resolved.

公开(公告)号：EP1550857A4

公开(公告)日：2006-12-20

申请号：EP03748660

申请日：2003-10-01

Applicant: HAMAMATSU PHOTONICS KK

Inventor： MARUNO TADASHI ,  IWASE FUMIO ,  SATO TAIGA

IPC: G01J1/58 ,  G01J3/28 ,  G01J3/44 ,  G01N21/64 ,  H04N5/321 ,  H04N5/335 ,  H04N5/353 ,  H04N5/3728 ,  H04N5/376 ,  G01J1/42

CPC classification number: G01J3/4406 ,  G01J3/2889 ,  G01N21/64 ,  H04N5/321

Abstract: A fluorescence measuring device having a CCD camera applied thereto that is capable of measuring a fluorescent component emitted from a measurement subject in response to an excitation pulse component with which the measuring subject is periodically irradiated. The fluorescence measuring device is at least provided with a CCD, and a control section. The CCD comprises a photoelectric conversion element that photoelectrically converts fluorescent component emitted from a measurement subject, and a charge-storage element that stores and transfers the charges photoelectrically converted by the photoelectric conversion element. The control section outputs an electron shutter signal for sweeping away the charges photoelectrically converted by the photoelectric conversion element, a readout signal for reading out the photoelectrically converted charges into the charge-storage element, and a transfer signal for successively transferring the charges that have been read out. Particularly, the control section outputs an electron shutter signal in response to the generation of an excitation pulse component and outputs a readout signal in response to the outputting of the electron shutter signal, and outputs transfer signals every predetermined number of times of outputting of the readout signal.