Abstract:
본 발명은 황기 추출물을 유효 성분으로 포함하는 조성물을 개시한다. 상기 조성물은 신체 에너지 소비 및 근육 대사를 촉진하는 효과를 가진다. 또한 본 발명은 상기 황기 추출물을 유효 성분으로 포함하는 조성물을 포함하는 약학 및 식품 조성물을 개시한다. 상기 약학 및 식품 조성물 또한 신체 에너지 소비 및 근육 대사를 촉진하는 효과를 가진다. 황기, 대사, 근육
Abstract:
PURPOSE: A composition containing syringaresinol for detoxification is provided to promote SIRT1(sirtuin 1) and cell activation and to enhance detoxification effect. CONSTITUTION: A composition for detoxification contains 0.001-20 wt% of syringaresinol as an active ingredient. The composition removes toxicity due to smoking. One or more selected from a flax seed extract, a Rutaceae extract, an Acanthopanax extract, a sesame extract, and a ginseng fruit extract contain syringaresinol. The composition enhances SIRT 1 expression. [Reference numerals] (AA) Expression degree of SIRT1; (BB) Compared to non-treated group %; (CC) Non-treated group; (DD) CSC syringaresinol 50ug/ml; (EE) CSC syringaresinol 100ug/ml;
Abstract:
본 발명은 녹차 함유 카테킨류 및 캄페롤(kaempferol) 성분을 함유하는 피지억제용 화장료 조성물에 관한 것이다. 보다 상세하게는, 본 발명의 피지억제용 화장료 조성물은 녹차의 구성성분 중 카테킨류 및 캄페롤(kaempferol) 성분을 함유함으로써 퍼옥시좀 증식체 활성화 수용체 아형 감마(PPAR-γ)의 활성을 감소시켜 우수한 피지의 생성을 억제하는 효과를 나타내고, 우수한 여드름 증상완화 효과를 나타낸다. 녹차 * 카테킨류 * 캄페롤 * 피지억제 * 여드름
Abstract:
PURPOSE: A composition containing plant extract for improving stomach and liver function is provided to relieve hangover and to recover fatigue. CONSTITUTION: A composition for improving stomach and liver function and reliving hangover contains 1-5 wt% of Curcuma longa extract, 1-30 wt% of milk thistle extract, and 4-55 wt% of chitooligosaccharides as an active ingredient. The composition further contains 5-50 wt% of plant mixture concentrate liquid including curcuma longa, Hordei Fructus Germinatus and Paeoniae Radix. A liver protection agent and an antifatigue agent contain the composition.
Abstract:
PURPOSE: A liver function improving composition and a food composition including thereof are provided to prevent side effects of the composition by using herb medicine components, and to secure the hangover curing effect. CONSTITUTION: A liver function improving composition contains 0.1~50 parts of steamed red ginseng extract by weight, and 0.1~50 parts of extract containing cornus officinalis, and schizandra chinensis, as active ingredients. The liver function improving composition additionally contains 0.1~50 parts of steamed red ginseng chips by weight.
Abstract:
A kit and a method for screening a candidate material which promotes the lipolysis is provided to increase the melanocortin 2 receptor accessory protein(Mrap) gene expression, promote the lipolysis by ACTH(adrenocorticotropic hormone) and prevent and treat the obesity relating disease. A kit for screening a candidate material which promotes the lipolysis comprises a vector containing a promoter and reporter gene. The promoter comprises 842th to 853th bases of the sequence number 1(SEQ ID NO:1) or additional 1569th to 1581th bases thereon. The reporter gene is a luciferase gene, enhanced green fluorescent protein(EGFP) gene, or beta galactosidase(lacZ) gene. A method for screening the candidate material which promotes the lipolysis comprises: a step of transfecting a test cell which is designated to express a PPAR-gamma(peroxisome proliferator-activated receptor-gamma) with the vector; a step of treating with the candidate material in the transfected test cell; and a step of measuring the expression degree of the reporter gene in the test cell and selecting the candidate material.
Abstract translation:提供用于筛选促进脂肪分解的候选物质的试剂盒和方法以增加黑皮质素2受体辅助蛋白(Mrap)基因表达,促进ACTH(促肾上腺皮质激素)的脂解,并预防和治疗肥胖症相关疾病。 用于筛选促进脂肪分解的候选物质的试剂盒包含含有启动子和报告基因的载体。 启动子包含序列号1(SEQ ID NO:1)的第842位至第853位碱基或其上第1569至1581位碱基。 报告基因是荧光素酶基因,增强型绿色荧光蛋白(EGFP)基因或β半乳糖苷酶(lacZ)基因。 用于筛选促进脂肪分解的候选物质的方法包括:转染被称为用载体表达PPAR-γ(过氧化物酶体增殖物激活受体-γ)的测试细胞的步骤; 在转染的测试细胞中用候选物质处理的步骤; 以及测定测定单元中的报道基因的表达程度并选择候选材料的步骤。
Abstract:
A composition for inhibiting the activity of glucose-6-phosphate dehydrogenase is provided to inhibit production of NADPH(nicotinamide adenine dinucleotide phosphate) and fat biosynthesis, so that the composition is useful for prevention and treatment of fat metabolism disorders including obesity, hyperlipidemia and diabetes. A composition for inhibiting the activity of glucose-6-phosphate dehydrogenase comprises the compounds represented by the formula(1) selected from epigallocatechin gallate, gallocatechin gallate, epicatechin gallate, catechin gallate, octyl gallate and lauryl gallate, wherein R^1 is H or OH, R^2 is a structural formula 1 or 2, R^3 is C3-C20 alkyl, X is a structural formula 3 or 4, and R^4 is H or a structural formula 5; and the compounds represented by the formula(1) is quercetin or myricetin.
Abstract:
본 발명은 대두(soybean)의 주요 이소플라보노이드(isoflavonoid) 중의 하나인 제니스테인(genistein)[5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one]의 신규한 용도에 관한 것으로서, 상기 제니스테인은 지방산 합성 효소(Fatty 유전자의 발현을 억제하고, 이를 통해 지방산 합성효소의 단백질 발현을 억제하며, 더 나아가 지방산 합성 효소(Fatty acid synthase; FAS)의 활성을 억제할 수 있으므로, 제니스테인은 지방산 합성 효소 억제용 조성물로서 사용될 수 있다. 또한, 지방산 합성 효소를 억제하는데 매우 뛰어난 효과를 나타내므로, 비만의 방지 및 치료에 유용하게 이용될 수 있다. 대두, 이소플라노이드, 제니스테인, 지방산 합성 효소, 지방산 합성, 억제, 비만, 방지, 치료, 조성물.