公开(公告)号：KR1020150010671A

公开(公告)日：2015-01-28

申请号：KR1020140108940

申请日：2014-08-21

Applicant: 대한민국(농촌진흥청장) ,  연세대학교 원주산학협력단

Inventor： 서우덕 ,  장기창 ,  한상익 ,  나지은 ,  오성환 ,  송유천 ,  강항원 ,  남민희 ,  김종배 ,  김사현 ,  박민

IPC: A61K36/899 ,  A61K31/7048 ,  A61P1/04 ,  A61P31/04

CPC classification number: A61K31/7048 ,  A23L29/035 ,  A61K36/899 ,  A61K2236/30

Abstract: 본 발명은 흑미 추출물 또는 흑미 용매 분획물을 유효성분으로 포함하는 헬리코박터 파이로리(
Helicobacter pylori ) 감염 질환의 예방 또는 치료용 약학적 조성물 및 흑미 용매 분획물을 제조하는 방법에 관한 것이다.
특히 흑미 추출물 또는 흑미유래 시아니딘 3-O-글루코사이드 흑미 분획물의 유효성분은 헬리코박터 파이로리의 생육 억제활성, 헬리코박터 파일로리 유레이즈 억제활성 및 CagA, VacA, SecA의 독소 분비억제 활성을 나타내며, 흑미 유래의 안전한 천연소재 이므로 인체에 안전성, 저독성 및 항생제 남용에 의한 내성균 발생을 억제하는 안전한 헬리코박터 파이로리 예방 또는 치료용 약학적 조성물, 건강식품, 음료 및 첨가물로 유용하게 이용 될 수 있다.

Abstract translation: 本发明涉及含有黑米提取物或黑米溶剂馏分作为预防或治疗感染幽门螺杆菌的疾病的活性成分的药物组合物和黑米溶剂级分的制备方法。 特别地，黑米提取物或黑米衍生的花青素3-O-葡萄糖苷黑米级分的活性成分显示抑制幽门螺杆菌生长，抑制幽门螺杆菌脲酶的活性，抑制CagA，VacA， 和SecA，并且是一种安全的天然物质衍生的黑米，因此可用作预防或治疗幽门螺杆菌的药物组合物，保健食品，饮料和添加剂，其对人体具有安全性和低毒性并且抑制 由于抗生素过度使用导致抗性细菌的产生。

公开(公告)号：KR1020150007890A

公开(公告)日：2015-01-21

申请号：KR1020130082503

申请日：2013-07-12

Applicant: 대한민국(농촌진흥청장)

Inventor： 한상익 ,  김병주 ,  나지은 ,  서우덕 ,  장기창 ,  이종희 ,  오성환 ,  최경진 ,  박지영 ,  남민희

IPC: A23L7/10

CPC classification number: A23L7/10 ,  A23L33/14 ,  A23V2002/00 ,  A23V2250/76

Abstract: 본 발명은 홍국쌀 100g을 기준으로 모나콜린 K 가 3500 mg 이상인 홍국쌀의 제조방법으로서, 찹쌀을 증자하는 제1단계; 및 증자된 찹쌀에 홍국균을 접종한 후 12일 이상 배양 및 발효시키는 제2단계를 포함하는 것인 제조방법을 제공한다.

Abstract translation: 本发明涉及一种基于100g红曲米生产具有3500mg的莫纳可林K的红曲米的方法，本发明的目的是有效提高活性莫纳可林K的含量以及总含量 莫纳可林K.本发明提供了一种生产红曲米的方法，该方法包括：蒸糯米的第一步; 在蒸糯米中接种红曲的第二步，培养发酵12天以上。

公开(公告)号：KR1020140065535A

公开(公告)日：2014-05-30

申请号：KR1020120129613

申请日：2012-11-15

Applicant: 대한민국(농촌진흥청장) ,  충북대학교 산학협력단

Inventor： 장기창 ,  서우덕 ,  한상익 ,  나지은 ,  오성환 ,  강현중 ,  김병주 ,  강항원 ,  남민희 ,  김대중 ,  김태명 ,  심태진

IPC: A61K36/899 ,  A61K31/352 ,  A61K31/35 ,  A61P29/00

CPC classification number: A61K31/352 ,  A61K36/899 ,  Y10S514/857 ,  Y10S514/886 ,  Y10S514/894 ,  Y10S514/914

Abstract: The present invention relates to an extract containing a polyphenol-based compound derived from sorghum and sorghum by-products and a pharmaceutical composition for prevention and treatment of inflammatory diseases containing the same as an active ingredient. More specifically, the present invention relates to: an extract containing a polyphenol-based compound derived from sorghum and sorghum by-products, which has a useful effect on prevention and treatment of inflammatory disease by separating a polyphenol-based compound showing an anti-inflammatory effect from a sorghum extract, and which can be used for the ingredients of food and medicines as well as a natural anti-inflammatory drug, etc.; and a pharmaceutical composition for prevention and treatment of inflammatory diseases containing the same as an active ingredient.

Abstract translation: 本发明涉及含有由高粱和高粱副产物衍生的多酚类化合物的提取物和用于预防和治疗含有其作为活性成分的炎性疾病的药物组合物。 更具体地说，本发明涉及：含有源自高粱和高粱副产物的多酚类化合物的提取物，其通过分离显示抗炎药物的多酚类化合物对预防和治疗炎性疾病有有效的作用 高粱提取物的作用，可用于食品和药物的成分以及天然抗炎药物等; 以及用于预防和治疗含有其作为活性成分的炎性疾病的药物组合物。

公开(公告)号：KR1020140056708A

公开(公告)日：2014-05-12

申请号：KR1020120121907

申请日：2012-10-31

Applicant: 대한민국(농촌진흥청장)

Inventor： 조준현 ,  이종희 ,  김상열 ,  송유천 ,  이지윤 ,  오성환 ,  손영보 ,  한상익 ,  여운상 ,  박동수 ,  남민희

IPC: A21D13/04 ,  A21D15/02 ,  A23L7/10

CPC classification number: A21D13/04 ,  A21D13/44 ,  A21D15/02

Abstract: The present invention relates to a method for manufacturing rice crepe, and more specifically, to a method for manufacturing rice crepe using the mixture of rice and tapioca starch instead of wheat flour. The method for manufacturing rice crepe according to one embodiment of the present invention includes a step of immersing rice into water, a step of crushing the immersed rice and obtaining rice powder, a step of obtaining dough by mixing the rice powder with the tapioca starch and adding water and salt, and a step of steaming the dough.

Abstract translation: 本发明涉及一种制造米绉的方法，更具体地说，涉及使用米和木薯淀粉代替小麦粉的混合物制造稻绉的方法。 根据本发明的一个实施方案的制造米绉的方法包括将米浸入水中的步骤，将浸米浸泡并获得米粉的步骤，通过将米粉与木薯淀粉混合获得面团的步骤和 加入水和盐，以及蒸熟面团的步骤。

公开(公告)号：KR1020140017818A

公开(公告)日：2014-02-12

申请号：KR1020120084430

申请日：2012-08-01

Applicant: 대한민국(농촌진흥청장) ,  연세대학교 원주산학협력단

Inventor： 서우덕 ,  장기창 ,  한상익 ,  나지은 ,  오성환 ,  송유천 ,  강항원 ,  남민희 ,  김종배 ,  김사현 ,  박민

IPC: A61K36/899 ,  A61P1/04 ,  A61P1/00

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating Helicobacter pylori infectious diseases which includes extract of black rice or black rice solvent fractions as an active ingredient and a method for manufacturing black rice solvent fractions. More specifically, the active ingredients of the black rice extract or black rice derived cyanidin-3-O-glucoside black rice fractions show activities of growth inhibition of the Helicobacter pylori, inhibition of Helicobacter pylori urease, and toxin secretion inhibition of CagA, VacA, SecA, and are safe and natural black rice derived materials so that active ingredients of the black rice extract or black rice derived cyanidin-3-O-glucoside black rice fractions can be used as the pharmaceutical composition, health supplement, drink and additives for preventing or treating the Helicobacter pylori which are safe, have low toxicity, and inhibits the generation of resistant bacteria caused by abusing antibiotics.

Abstract translation: 本发明涉及一种用于预防或治疗幽门螺杆菌感染性疾病的药物组合物，其包括黑米或黑米溶剂级分的提取物作为活性成分，以及黑米溶剂级分的制造方法。 更具体地说，黑米提取物或黑米衍生的花青素-3-O-葡萄糖苷黑米级部分的活性成分显示了幽门螺旋杆菌的生长抑制活性，幽门螺杆菌脲酶的抑制以及CagA，VacA的毒素分泌抑制， SecA，并且是安全和天然的黑米衍生材料，使得黑米提取物或黑米衍生的花青素-3-O-葡萄糖苷黑米级分的活性成分可用作药物组合物，健康补充剂，饮料和预防添加剂 或治疗安全的幽门螺杆菌，具有低毒性，并且抑制由滥用抗生素引起的抗性细菌的产生。

公开(公告)号：KR101296208B1

公开(公告)日：2013-08-13

申请号：KR1020120081932

申请日：2012-07-26

Applicant: 대한민국(농촌진흥청장) ,  경북대학교 산학협력단

Inventor： 한상익 ,  장기창 ,  서우덕 ,  나지은 ,  오성환 ,  최경진 ,  강항원 ,  남민희 ,  최진현

IPC: D01F1/10 ,  D01D5/00 ,  D01F6/14 ,  D01D1/02 ,  A61L15/10 ,  A61L26/00

CPC classification number: D01F1/103 ,  A61L15/10 ,  A61L26/0014 ,  D01D1/02 ,  D01D5/0015 ,  D01F6/14

Abstract: PURPOSE: A polyvinyl alcohol nanofiber which contains sorghum pigment is provided to show high antibiotic material and be used as wound coating flux which is medical material due to no cytotoxicity. CONSTITUTION: The sorghum by-product extract is the golden chalsusu stem extract and the golden chalsusu stem extract. The component of the sorghum extract or the sorghum by-product extract is chemical formula 1 or chemical formula 2.

Abstract translation: 目的：提供含有高粱颜料的聚乙烯醇纳米纤维，以显示高抗生素材料，并且由于没有细胞毒性而用作医疗材料的伤口涂层助焊剂。 构成：高粱副产品提取物是金黄色素提取物和金黄色素提取物。 高粱提取物或高粱副产物提取物的组分是化学式1或化学式2。

公开(公告)号：KR1020120121717A

公开(公告)日：2012-11-06

申请号：KR1020110039686

申请日：2011-04-27

Applicant: 대한민국(농촌진흥청장) ,  경북대학교 산학협력단 ,  창원대학교 산학협력단

Inventor： 서명철 ,  우관식 ,  강종래 ,  이재생 ,  송석보 ,  오병근 ,  고지연 ,  남민희 ,  김창순 ,  김영호

IPC: A21D13/00 ,  A21D13/04

Abstract: PURPOSE: A producing method of healthy bread containing unpolished red sorghum powder is provided to mix the red sorghum powder with flour before fermenting. CONSTITUTION: A producing method of healthy bread containing unpolished red sorghum powder comprises the following steps: crushing unpolished red sorghum to obtain powder; mixing flour, yeast, and water to obtain flour dough; adding the red sorghum powder into the flour dough to obtain mixed dough; fermenting the mixed dough at 20-40 deg. C; and baking the fermented dough at 100-250 deg. C. [Reference numerals] (AA) Mixing 1(mixing materials for 1.5 minutes using a speed1 kneader); (BB) Mixing 2(mixing materials for 2 minutes using a speed2 kneader); (S1) Preparing materials; (S1-1) Preparing main materials(flour, sorghum powder); (S1-2) Preparing secondary materials(sugar, salt, skimmed milk powder, gluten, SSL); (S2) Mixing the materials; (S2-1) Mixing water, yeast, and flour; (S2-2) Mixing 1(mixing materials for 2.5 minutes using the speed1 kneader); (S2-3) Mixing 2(mixing materials for 1.5 minutes using the speed2 kneader); (S2-4) Adding shortening; (S2-5) Mixing (mixing materials using the speed1 and speed2 kneaders for 1.5 minutes each); (S3) Mixing sorghum powder; (S3-1) Adding the sorghum powder into dough; (S4) Fermenting and molding; (S4-1) Maintaining the temperature of the dough at 25 deg. C; (S4-2) Fermenting the dough in a fermenter(30 deg. C, 85% humidity, 40 minutes); (S4-3) Punching and dividing the dough before settling for 10 minutes, and molding; (S4-4) Inserting the dough into an oven tray, and settling for 50 minutes; (S5) Baking and packaging; (S5-1) Backing in a 180 deg. C oven for 20 minutes; (S5-2) Cooling, dehumidifying, and packaging

Abstract translation: 目的：提供含有未抛光红高粱粉的健康面包的生产方法，在发酵前将红高粱粉与面粉混合。 构成：含有未抛光的红高粱粉的健康面包的制作方法，包括以下步骤：粉碎未经抛光的红高粱获得粉末; 混合面粉，酵母和水，得到面粉; 将红高粱粉加入面粉面团中，得到混合面团; 在20-40度发酵混合面团 C; 并在100-250度烘烤发酵面团。 （AA）混合1（使用速度1捏合机混合1.5分钟）; （BB）混合2（使用speed2捏合机混合2分钟）; （S1）准备材料; （S1-1）准备主料（面粉，高粱粉）; （S1-2）制备次生材料（糖，盐，脱脂奶粉，面筋，SSL）; （S2）混合材料; （S2-1）混合水，酵母和面粉; （S2-2）混合1（使用speed1捏合机混合料2.5分钟）; （S2-3）混合2（使用speed2捏合机混合物料1.5分钟）; （S2-4）添加起酥油; （S2-5）混合（使用speed1和speed2捏合机混合材料1.5分钟）; （S3）混合高粱粉; （S3-1）将高粱粉加入面团; （S4）发酵和成型; （S4-1）将面团的温度保持在25度。 C; （S4-2）在发酵罐（30℃，湿度85％，40分钟）中发酵生面团; （S4-3）在沉降10分钟之前冲压和分割面团，并进行成型; （S4-4）将面团插入烤箱托盘中，沉降50分钟; （S5）烘焙包装; （S5-1）支撑在180度 C烤箱20分钟; （S5-2）冷却，除湿和包装

公开(公告)号：KR101161231B1

公开(公告)日：2012-07-20

申请号：KR1020090066787

申请日：2009-07-22

Applicant: 대한민국(농촌진흥청장)

Inventor： 한상익 ,  오기원 ,  하태정 ,  임시규 ,  고종민 ,  백인열 ,  박금룡 ,  남민희 ,  강항원 ,  안진곤

IPC: A01G7/00 ,  A01G7/04 ,  A23L11/00

Abstract: 본 발명은 콩 종자의 이소플라본 함량을 증가시키는 방법에 관한 것으로서, 더욱 상세하게는 콩의 생육기간 중 완전 전개엽을 착생한 최상위 4마디 중 1마디의 꼬투리에서 종실이 비대해 지는 시기에 일정세기의 조명을 일정시기동안 처리하여 콩이 지속적으로 빛에 노출되게 하여 종자의 이소플라본 함량을 증가시키는 방법에 관한 것이다.
콩 종자, 이소플라본 함량, 조명

公开(公告)号：KR101156017B1

公开(公告)日：2012-06-27

申请号：KR1020090015067

申请日：2009-02-23

Applicant: 대한민국(농촌진흥청장)

Inventor： 박동수 ,  이기환 ,  한상익 ,  남민희 ,  송송이 ,  왕회정 ,  박수권 ,  이봉춘 ,  송유천 ,  강항원

IPC: C12N15/29 ,  A01H1/00

Abstract: PURPOSE: A rice plant with transformed giant embryonic rice is provided to ensure a heavier product than conventional embryos and to obtain rice containing zinc and iron. CONSTITUTION: A cytochrome P450 of giant embryonic rice comprises a base sequence which encodes an amino acid sequence of cytochrome P450 and encodes leucine to a 395th amino acid after translation. A cytochrome P450 gene of rice is a cDNA encoding cytochrome P450. A rice plant is produced by transforming rice plant with a recombinant vector having cytochrome P450 gene. The giant embryonic rice is YR23517Acp79.

公开(公告)号：KR1020110085758A

公开(公告)日：2011-07-27

申请号：KR1020100005714

申请日：2010-01-21

Applicant: 대한민국(농촌진흥청장)

Inventor： 한상익 ,  장기창 ,  서우덕 ,  이제봉 ,  박수권 ,  남민희 ,  강항원 ,  오성환 ,  이기환 ,  박동수 ,  김상열 ,  황운하 ,  최경진

IPC: A61K36/899 ,  A61K31/37 ,  A61K31/7048 ,  A61P17/00

CPC classification number: A61K31/192 ,  A23L29/035 ,  A61K8/368 ,  A61K8/498 ,  A61K8/602 ,  A61K8/97 ,  A61K31/352 ,  A61K31/7048 ,  A61K36/8998 ,  A61K2236/33

Abstract: PURPOSE: A method for preparing extract derived from young barley leaf is provided to isolate novel ingredients and to be used as a functional material supply source. CONSTITUTION: A young barley leaf extract with an antioxidative activity is prepared using an organic solvent. The young barley leaf is collected in a length of 10-20 cm and is freeze-dried. The organic solvent is methanol or ethanol. The ethanol is 80-90 weight% ethanol solution. A composition for skin whitening or anti-aging contains the extract as an active ingredient. A health food for skin whitening or anti-aging contains the extract as an active ingredient. A solvent fraction of the extract contains one or more compounds selected from compound of chemical formulas 1-4.

Abstract translation: 目的：提供一种制备从年轻大麦叶提取的提取物的方法，用于分离新成分并用作功能材料供应源。 构成：使用有机溶剂制备具有抗氧化活性的年轻大麦叶提取物。 收集年轻的大麦叶，长度为10-20厘米，冷冻干燥。 有机溶剂为甲醇或乙醇。 乙醇为80-90重量％乙醇溶液。 用于皮肤美白或抗衰老的组合物含有提取物作为活性成分。 用于皮肤美白或抗衰老的保健食品含有提取物作为活性成分。 提取物的溶剂馏分含有一种或多种选自化学式1-4化合物的化合物。