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公开(公告)号：HK1040704A1
公开(公告)日：2002-06-21
申请号：HK02102528
申请日：2002-04-04
Applicant: BASF AG
Inventor： BERNARD HARALD , RIECHERS HARTMUT
Abstract: A process for racemate resolution of 2-hydroxypropionic acids by reacting the racemic acid with an optically active base and subsequently separating off a diastereomeric salt of acid and base comprises using 1-(4-chlorophenyl)ethylamine as optically active base.
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公开(公告)号：SI9520061B
公开(公告)日：2002-02-28
申请号：SI9520061
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号：CA2099497C
公开(公告)日：2001-12-25
申请号：CA2099497
申请日：1991-11-21
Applicant: BASF AG
Inventor： HORNBERGER WILFRIED , SCHMIED BERNHARD , HOEFFKEN HANS W , BERNARD HARALD
Abstract: The description relates to peptides of the formula (I), in which X, A1-A7, Y and W have the meanings given in the de- scription, and their production. The peptides are suitable for combatting diseases.
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公开(公告)号：PL180652B1
公开(公告)日：2001-03-30
申请号：PL32115995
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号：CA2347758A1
公开(公告)日：2000-05-11
申请号：CA2347758
申请日：1999-10-16
Applicant: BASF AG
Inventor： RIECHERS HARTMUT , BERNARD HARALD
Abstract: The invention relates to racemate splitting of 2-hydroxypropionic acids by reacting racemic acid with an optically active base and subsequently separating a diastereomeric salt from the acid and the base. The invention i s characterized in that 1-(4-chlorophenyl)ethylamine is used as optically acti ve base.
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Patent Agency Ranking
公开(公告)号：AT185349T
公开(公告)日：1999-10-15
申请号：AT96925744
申请日：1996-07-12
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANSSEN BERND , ULRICH KARL , KLING ANDREAS , MUELLER STEFAN , RITTER KURT , ZIERKE THOMAS
IPC: C07K1/02 , C07K1/12 , C07K5/06 , C07K5/078 , C07K5/08 , C07K5/083 , C07K5/10 , C07K5/103 , C07K7/06
Abstract: PCT No. PCT/EP96/03073 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05162 PCT Pub. Date Feb. 13, 1997A process for preparing pentapeptides of the formula I where A and R1-R3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II where R1 and R2 have the abovementioned meanings, and eliminating the group -NR1R2 by hydrolysis where appropriate the peptide obtained in this way.
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公开(公告)号：HU9900089A2
公开(公告)日：1999-05-28
申请号：HU9900089
申请日：1996-10-30
Applicant: BASF AG
Inventor： AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , DE ARRUDA MONIKA , HAUPT ANDREAS , JANSSEN BERND , KLING ANDREAS , MUELLER STEFAN , RITTER KURT , ROBINSON SIMON , ZIERKE THOMAS
Abstract: Novel peptides of the formulaA-B-D-E-F-L,wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
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公开(公告)号：AU705143B2
公开(公告)日：1999-05-13
申请号：AU6615496
申请日：1996-07-12
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANSSEN BERND , ULRICH KARL , KLING ANDREAS , MULLER STEFAN , RITTER KURT , ZIERKE THOMAS
IPC: C07K1/02 , C07K1/12 , C07K5/06 , C07K5/078 , C07K5/08 , C07K5/083 , C07K5/10 , C07K5/103 , C07K7/06
Abstract: PCT No. PCT/EP96/03073 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05162 PCT Pub. Date Feb. 13, 1997A process for preparing pentapeptides of the formula I where A and R1-R3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II where R1 and R2 have the abovementioned meanings, and eliminating the group -NR1R2 by hydrolysis where appropriate the peptide obtained in this way.
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公开(公告)号：ES2126279T3
公开(公告)日：1999-03-16
申请号：ES95917962
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND
Abstract: Compounds of the formulawhere R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.
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公开(公告)号：BR9611987A
公开(公告)日：1999-02-17
申请号：BR9611987
申请日：1996-12-11
Applicant: BASF AG
Inventor： WYMANN JURGEN , BERNARD HARALD , ULLRICH MARTINA , BARLOZZARI TEREZA , RITTER KURT , LIETZ HELMUT , KLING ANDREAS , JANSSEN BERND , HEGE HANS-GUENTHER , HAUPT ANDREAS , BUSCHMANN ERNEST , AMBERG WILHELM , ZIERKE THOMAS
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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