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公开(公告)号：EP0344770A1
公开(公告)日：1989-12-06
申请号：EP89109929.3
申请日：1989-06-01
Inventor： Fischler, Henryk , Lipkin, Ziv , Aizinbud, Eliezer , Lehrer, Rami A. , Tadmor, Amnon , Nachshon, Aharon
CPC classification number: A61B5/0031 , A61B5/0002 , A61B5/076 , A61B5/117 , A61B10/0012 , A61B2010/0016
Abstract: Apparatus for measuring in vivo tissue impedance comprising:
means (10) to be implanted into the body tissue (12) for sensing the impedance thereof and for providing an output signal corresponding to the sensed impedance to a remote location.
receiver means (62, 64, 66, 68) located at the remote location for receiving the output signal and
means (80) associated with the receiver for displaying the measured impedance value.Abstract translation: 一种用于体内组织阻抗包括测量：装置（10），以用于感测其阻抗和用于提供输出信号对应于所述感测到的阻抗到远程位置被植入到身体组织（12）。 指位于远程位置处的用于接收与所述接收器，用于显示所测量的阻抗值相关联的输出信号的装置（80）接收器（62，64，66，68）。
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公开(公告)号：EP0305968A2
公开(公告)日：1989-03-08
申请号：EP88114131.1
申请日：1988-08-30
Inventor： Mirelman, David , Wilchek, Meir
IPC: A61K9/18 , A61K9/14 , A61K47/00 , A61K31/415 , A61K31/285 , A61K31/47 , A61K31/435 , A61K31/165 , A61K31/42 , A61K31/255 , A61K31/54
CPC classification number: A61K9/1676 , A61K9/167 , A61K47/52 , Y02A50/486
Abstract: The invention relates to pharmaceutical compositions for use against protozoa. The compositions comprise particles in the micron-size range which are physiologically acceptable to humans and which can be ingested by protozoa. The particles, which can be of natural materials such as silica or the like, serve as carrirs of an effective anti-protozoal drug. A variety of anti-amebic drugs can be bound to such particles.
Abstract translation: 本发明涉及用于抗原生动物的药物组合物。 组合物包含微生物范围的颗粒，它们是生理上可接受的并且可被原生动物吸收。 可以是天然材料如二氧化硅等的颗粒用作有效的抗原虫药物的卡里尔。 各种抗阿米巴药物可以与这种颗粒结合。
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83.发明公开Novel crystalline aluminosilicate zeolite catalysts and their use in the vapor phase isomerization of xylenes 失效催化剂制得的结晶硅铝酸盐和它们的在气相中进行Xylolisomerisation使用。
公开(公告)号：EP0258870A1
公开(公告)日：1988-03-09
申请号：EP87112738.7
申请日：1987-09-01
Inventor： Fraenkel, Dan , Levy, Moshe
CPC classification number: C01B39/40 , B01J29/40 , C07C5/2708 , C07C15/067
Abstract: The invention relates to novel crystalline aluminosilicate catalysts and to a process for the production of such catalysts. The invention further relates to such process where highly specific starting materials are reacted under closely controlled conditions of reaction to produce the desired products. Furthermore, the invention relates to a highly selective process for the isomerization of xylene by means of such catalyst. Starting materials comprising mainly m-xylene are readily converted to isomeric mixtures of xylene close to the equilibrium composition.
Abstract translation: 本发明涉及一种新颖的结晶硅铝酸盐的催化剂和用于生产检查催化剂的方法。 本发明还涉及这样的过程，其中高度特异性的起始原料反应，以产生所期望的产物的严格控制的条件下反应。 进一步，本发明涉及一种用于二甲苯的被搜索催化剂进行异构化高度选择性的处理。 主要包含间二甲苯的起始原料容易地转化为二甲苯接近平衡组成的异构体混合物。
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84.发明公开Use of amphiphilic amide compounds in Z-type Langmuir-Blodgett films 失效Z-Typ-Langmuir-Blodgett-Filmen的Verwendung von amphiphilischen Amidverbindungen。
公开(公告)号：EP0255718A2
公开(公告)日：1988-02-10
申请号：EP87111255.3
申请日：1987-08-04
Inventor： Lahav, Meir , Leiserowitz, Leslie , Sagiv, Jacob , Popovitch-Biro, Ronit , Hill, Karlheinz , Landau, Ehud
IPC: C07C233/01 , C07C233/46 , C07C233/45 , C07C237/04 , C07D213/50 , H01L41/187 , H01L37/02
CPC classification number: H01L37/025 , C07D215/50 , H01L41/193
Abstract: Described are novel amphiphilic amide compounds which are suited for the production of multilayer films which have piezoelectric and pyroelectric properties, and which provide second harmonic generation.It is possible to prepare from these compounds polar single-layer and multi-layer films by depositing them on a substrate. When such substrate is a solid support, polar Z-type Langmuir-Blodgett films are obtained. Upon compression of films of such compounds, at an air/water interface, stable Langmuir monolayers are formed.
Abstract translation: 描述了适用于制备具有压电和热电性质并且提供二次谐波产生的多层膜的新型两亲性酰胺化合物。可以通过将这些化合物极性单层和多层膜沉积在 底物。 当这种基底是固体支持物时，获得极Z型Langmuir-Blodgett膜。 在压缩这些化合物的膜时，在空气/水界面处形成稳定的Langmuir单层。
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85.发明授权
公开(公告)号：EP0117470B1
公开(公告)日：1987-09-09
申请号：EP84101404.6
申请日：1984-02-10
Inventor： Rubinstein, Menachem , Friedlander, Jossef , Fischer, Dina
CPC classification number: C07K14/57 , A61K38/00 , B01D15/362 , B01D61/145 , B01D61/18 , B01D2313/40
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Patent Agency Ranking86.发明公开A monoclonal antibody recognizing a cytotoxin, a hybridoma cell line expressing same and a process for the preparation of a purified cytotoxin 失效针对细胞毒素的单克隆抗体，用于制备纯化的细胞毒素相同的产生杂交瘤和方法。
公开(公告)号：EP0186833A2
公开(公告)日：1986-07-09
申请号：EP85115918.6
申请日：1985-12-13
Inventor： Wallach, David , Hahn, Talia , Eshhar, Zelig
CPC classification number: G01N33/56972 , A61K38/21 , C07K14/47 , C07K16/24 , G01N33/56966 , G01N2333/525 , A61K2300/00
Abstract: A cytotoxic protein expressed by human peripheral blood mononuclear cells is isolated in essentially homogenous form. This protein may be used to elicit production of polyclonal or monoclonal anti-cytotoxin antibodies. Hybridomas secreting anti-cytotoxin antibodies are identified by a solid phase bioassay. The antibodies are useful in the immunopurification of cytotoxins. The purified cytotoxic proteins are useful for the treatment of virus-infected or tumor target cells, either alone or in combination with interferon or a metabolic blocker.
Abstract translation: 通过人外周血单核细胞中过表达细胞毒性蛋白质在本质上均匀的形状是分离的。该蛋白可用于引发生产多克隆或单克隆抗细胞毒素抗体的产生。 杂交瘤分泌的抗细胞毒素抗体是通过固相生物测定识别。 抗体是在细胞毒素的免疫纯化有用。 将纯化的细胞毒性蛋白是病毒感染或肿瘤靶细胞，无论是单独使用或与干扰素或代谢阻滞剂组合的治疗是有用的。
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87.发明公开COMPOSITIONS FOR THE ALLEVATION, TREATMENT AND DIAGNOSIS OF ARTHRITIC DISEASE AND RELATED CONDITIONS 失效组合物用于减轻，治疗和疾病和相关病症Bestimmungung arthritschen。
公开(公告)号：EP0181364A1
公开(公告)日：1986-05-21
申请号：EP85902080.0
申请日：1985-04-29
Inventor： STANFORD, John, Lawson , COHEN, Irun, Robert , FRENKEL, Ayala , HOLOSHITZ, Joseph , VAN EDEN, Willem , ROOK, Graham, Arthur, William
Abstract: Des compositions pharmaceutiques permettant de soulager la douleur due à des maladies arthritiques contiennent en tant qu'ingrédients actifs des mycobactéries ou des fractions de celles-ci, obtenues par exemple par fractionnement dans certains solvants. Les compositions peuvent également être utilisées pour des vaccinations. Est également décrite une analyse pour le diagnostic de maladies arthritiques, et un kit pour effectuer une telle analyse.
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88.发明公开Process for producing interferon (IFN-gamma) subtypes 26K and 21K 失效Verfahren zur Herstellung von Interferon（IFN-gamma）des Typs 26K und 21K。
公开(公告)号：EP0117470A1
公开(公告)日：1984-09-05
申请号：EP84101404.6
申请日：1984-02-10
Inventor： Rubinstein, Menachem , Friedlander, Jossef , Fischer, Dina
CPC classification number: C07K14/57 , A61K38/00 , B01D15/362 , B01D61/145 , B01D61/18 , B01D2313/40
Abstract: Described is a process for the purification of human immune interferon (IFN-y) to homogeneity without appreciable loss of biological activity by the use of chromatography on controlled-pore glass, ultrafiltration and high performance cation exchange chromatography, resulting in essentially pure human interferon subtypes 21 K and 26K. Furthermore, there are described pharmaceutical compositions containing said purified interferons.
Abstract translation: 描述了通过在受控孔玻璃上的色谱法，超滤和高性能阳离子交换色谱法将人免疫干扰素（IFN-γ）纯化成均匀性而没有明显的生物活性损失的方法，导致基本上纯的人干扰素亚型 21K和26K。 此外，描述了含有所述纯化的干扰素的药物组合物。
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89.发明授权COMPOSITION COMPRISING S-ALLYLMERCAPTO-N-ACETYLCYSTEINE (ASSNAC) FOR UP-REGULATION OF CELLULAR GLUTATHIONE LEVEL 有权使用S-烯丙基硫醇-N-乙酰半胱氨酸（ASSNAC）对于蜂窝上调谷胱甘肽MIRROR COMPOSITION
公开(公告)号：EP2139465B1
公开(公告)日：2012-09-26
申请号：EP08738301.4
申请日：2008-05-01
Inventor： SAVION, Naphtali , MIRELMAN, David , RABINKOV, Aharon , KHENKIN, Alex
IPC: A61K31/198 , A61P39/06 , A61P25/28 , A61P25/16 , A61P19/02 , A61P9/10 , A61P13/12 , A61P35/00 , A61P3/10 , A61P11/00 , A61P27/02
CPC classification number: A61K31/198
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公开(公告)号：EP2204187B1
公开(公告)日：2012-05-09
申请号：EP10003160.8
申请日：1999-11-28
Inventor： Arnon, Ruth , Ben-Yedidia, Tamar , Levi, Raphael
IPC: A61K39/145 , C07K14/11
CPC classification number: C12N7/00 , A61K39/12 , A61K39/145 , A61K39/385 , A61K2039/543 , A61K2039/58 , A61K2039/6068 , C12N2760/16134
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