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公开(公告)号：KR101582384B1
公开(公告)日：2016-01-05
申请号：KR1020130140211
申请日：2013-11-18
Applicant: 서울대학교산학협력단
CPC classification number: G01N33/5434 , C12Q1/6825 , C12Q1/708 , G01N33/531 , G01N33/54313 , G01N33/552
Abstract: 코드화된고분자미세입자코어; 및상기미세입자코어를둘러싼실리카쉘을포함하는코드화된고분자미세입자및 이를이용한다중바이오분석방법이제공된다. 또한광경화성물질, 및상기광경화성물질과중합가능한작용기와알콕시실릴기를함께구비한링커의혼함물을제공하는단계; 패턴화된에너지를인가하여상기혼합물을경화하고, 코드화함으로써코드화된고분자미세입자코어를얻는단계; 및상기코드화된고분자미세입자코어에실리카전구체를처리하여상기코드화된고분자미세입자코어위에실리카쉘을형성하는단계를포함하는코드화된고분자미세입자의제조방법이제공된다.
Abstract translation: 提供编码的聚合物微粒和使用编码的聚合物微粒的多重生物测定。 每个编码的聚合物微粒包括编码的聚合物微粒核心和围绕微粒核心的二氧化硅壳。 还提供了一种制备编码的聚合物微粒的方法。 该方法包括：将可光固化材料与具有可光固化材料和烷氧基甲硅烷基可聚合的官能团的连接体混合; 施加图案化的能量以固化混合物，然后编码以获得编码的聚合物微粒核心; 以及用二氧化硅前体处理编码的聚合物微粒核心，以在每个编码的聚合物微粒核心上形成二氧化硅壳。
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公开(公告)号：KR101540518B1
公开(公告)日：2015-07-31
申请号：KR1020130128747
申请日：2013-10-28
Applicant: 서울대학교산학협력단
Abstract: 포함된타겟물질의종류에따라코드화된마이크로캡슐로서, 상기타겟물질을포함하는친수성의액체코어(core); 및상기액체코어를둘러싼소수성의쉘(shell)을가지며, 상기쉘 표면에도입된그래픽코드를포함하는코드화된마이크로캡슐이제공된다.
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公开(公告)号：KR101471246B1
公开(公告)日：2014-12-10
申请号：KR1020120080601
申请日：2012-07-24
Applicant: 서울대학교산학협력단
CPC classification number: C12P19/34 , B01J2219/00315 , B01J2219/00441 , B01J2219/00468 , B01J2219/005 , B01J2219/00596 , B01J2219/00648 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , C40B20/02 , C40B50/14 , C40B60/04
Abstract: 고체지지체상에존재하는올리고뉴클레오타이드들의복제라이브러리를갖는염기서열분석기판을제공하는단계; 상기복제라이브러리를시퀀싱하는단계; 상기염기서열분석기판상의상기고체지지체의실측위치정보를얻는단계; 상기시퀀싱의결과로주어지는상기고체지지체로부터발생한신호의픽셀정보와상기실측위치정보를맵핑하는단계; 상기맵핑한결과를이용하여원하는염기서열을갖는상기고체지지체를상기염기서열분석기판으로부터추출하는단계; 및상기추출된상기고체지지체상의올리고뉴클레오타이드를증폭하여대량으로복제하는단계를포함하는고순도뉴클레오타이드의대량생산방법이제공된다.
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Patent Agency Ranking
公开(公告)号：KR1020140111224A
公开(公告)日：2014-09-18
申请号：KR1020140026952
申请日：2014-03-07
Applicant: 서울대학교산학협력단
IPC: C12Q1/68
CPC classification number: C12N15/1065 , C12Q1/6837 , C12Q2565/513 , C12Q2565/514 , C12Q1/6834
Abstract: Provided is a heterogeneous DNA barcoding method comprising the steps of: (a) providing a DNA microarray including DNA spots which are separated from each other by means of a barcode base sequence; (b) providing a microwell array including microwells corresponding to the spatial position of the DNA spots on the DNA microarray; (c) loading a solution of a sample including target base sequences into the microwells; (d) producing fine reactive spaces, which are formed by spatially separating the DNA spots by means of the microwells, by combining the DNA microarray with the microwell array; and (e) combining the base sequence information of the DNA spots with the base sequence information of the sample by making the target base sequence of the sample reacted with the base sequence of the DNA spots in the fine reaction space; and (f) obtaining a byproduct including the barcode base sequence by separating the DNA microarray and the microwell array.
Abstract translation: 提供了一种异源DNA条形码方法，其包括以下步骤：（a）提供包含通过条形码碱基序列彼此分离的DNA斑点的DNA微阵列; （b）提供微孔阵列，其包括对应于DNA微阵列上的DNA斑点的空间位置的微孔; （c）将包含靶基序列的样品溶液加载到微孔中; （d）通过将DNA微阵列与微孔阵列组合而产生通过微孔空间分离DNA斑点而形成的细小反应空间; 和（e）通过使样品的靶碱基序列与微细反应空间中的DNA斑点的碱基序列反应，将DNA斑点的碱基序列信息与样品的碱基序列信息组合; 和（f）通过分离DNA微阵列和微孔阵列获得包括条形码碱基序列的副产物。
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公开(公告)号：KR1020140063480A
公开(公告)日：2014-05-27
申请号：KR1020130140211
申请日：2013-11-18
Applicant: 서울대학교산학협력단
CPC classification number: G01N33/5434 , C12Q1/6825 , C12Q1/708 , G01N33/531 , G01N33/54313 , G01N33/552
Abstract: Provided are an encoded polymer microparticles comprising an encoded polymer microparticle core and a silica shell encompassing the microparticle core; and a multiplexed bioanalysis method using the same. In addition, provided is a method for preparing an encoded polymer microparticles, comprising the steps of: providing a mixture of a radiation curable material, and a linker comprising a functional group capable of being polymerized with the radiation curable material, and an alkoxysilyl group; obtaining an encoded polymer microparticle core by applying a patterned energy to cure the mixture and encoding the same; and forming a silica shell on the encoded polymer microparticle core by treating the encoded polymer microparticle core with a silica precursor.
Abstract translation: 提供了编码聚合物微粒，其包含编码的聚合物微粒核和包围微粒核的二氧化硅壳; 和使用其的多重生物分析方法。 此外，提供了制备编码的聚合物微粒的方法，包括以下步骤：提供可辐射固化材料的混合物和包含能够与可辐射固化材料聚合的官能团的连接体和烷氧基甲硅烷基; 通过施加图案化的能量来固化混合物并编码它们来获得编码的聚合物微粒核; 以及通过用二氧化硅前体处理编码的聚合物微粒芯，在编码的聚合物微粒核上形成二氧化硅壳。
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公开(公告)号：KR1020130059431A
公开(公告)日：2013-06-05
申请号：KR1020137008608
申请日：2010-04-14
Applicant: 서울대학교산학협력단
CPC classification number: B01J19/12 , B01J19/123 , B82Y20/00 , B82Y25/00 , C01P2006/42 , C08K3/22 , C08K9/08 , C08K2201/01 , C08K2201/011 , C09C1/24 , C09C3/10 , C09D7/62 , C09D7/69 , C09D11/50 , G02B1/005 , G02B5/201 , G02B2207/101 , G02F1/09 , G02F1/29 , H01F1/0063 , H01F1/344 , Y10T428/24802
Abstract: PURPOSE: A method for generating a structural color is provided to generate a structure color-based film which changes color according to angles. CONSTITUTION: A composition(100) for generating a structural color includes a curable material(110) and magnetic nanoparticles(120) dispersed in the curable material. A structural color-based printed product includes a solid medium and magnetic nanoparticles dispersed in the solid medium. The magnetic nanoparticles form chain structures by being regularly aligned to at least one axial direction. Wavelength of light, which is diffracted from external incident light, is determined according to the alignment gap of the magnetic nanoparticles. A method for generating a structural color includes a step for generating color by immobilizing the alignment structure of the magnetic nanoparticles in a medium and diffracting light based on the alignment structure.
Abstract translation: 目的：提供一种产生结构颜色的方法，以产生根据角度改变颜色的基于结构的基于颜色的胶片。 构成：用于产生结构颜色的组合物（100）包括分散在可固化材料中的可固化材料（110）和磁性纳米颗粒（120）。 结构色彩印刷产品包括固体介质和分散在固体介质中的磁性纳米颗粒。 磁性纳米颗粒通过与至少一个轴向方向规则对准而形成链结构。 根据磁性纳米粒子的取向间隙确定从外部入射光衍射的光的波长。 用于产生结构颜色的方法包括通过将磁性纳米颗粒的取向结构固定在介质中并基于对准结构衍射光来产生颜色的步骤。
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公开(公告)号：KR1020130046356A
公开(公告)日：2013-05-07
申请号：KR1020120114103
申请日：2012-10-15
Applicant: 서울대학교산학협력단
CPC classification number: C12P19/34 , B01J2219/00315 , B01J2219/00441 , B01J2219/00468 , B01J2219/005 , B01J2219/00596 , B01J2219/00648 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , C40B20/02 , C40B50/14 , C40B60/04 , C12Q1/6811 , C12Q1/6834
Abstract: PURPOSE: A mass production method of a high purity nucleotide is provided to quickly and accurately isolate a microbead with a predetermined sequence and to amplify the sequence. CONSTITUTION: A mass production method of a high purity nucleotide comprises: a step of providing a sequencing substrate with a replication library of oligonucleotides existing on a solid support(S110); a step of sequencing the replication library(S120); a step of obtaining measured location information of the solid support(S130); a step of mapping pixel information of a signal generated from the solid support and the measured location information(S140); a step of extracting a desired sequence from the sequencing substrate using the mapping result(S150); and a step of amplifying a large amount of oligonucleotides on the solid support(S160). [Reference numerals] (AA) Start; (BB) End; (S110) Provide a sequencing analysis substrate with a replication library of oligos on a solid support; (S120) Sequence the replication library; (S130) Obtain the actual location information of the solid support; (S140) Map pixel information and the actual location information; (S150) Extract the solid support using a mapping result; (S160) Massively replicate by amplifying the oligos of the extracted solid support
Abstract translation: 目的：提供高纯度核苷酸的大规模生产方法，以预定的顺序快速准确地分离微珠并扩增序列。 构成：高纯度核苷酸的批量生产方法包括：向测序底物提供存在于固体支持物上的寡核苷酸复制文库的步骤（S110）; 对复制库进行排序的步骤（S120）; 获取固体支持物的测量位置信息的步骤（S130）; 映射从固体支持物产生的信号的像素信息和所测量的位置信息的步骤（S140）; 使用映射结果从测序底物提取期望的序列的步骤（S150）; 和在固体支持物上扩增大量寡核苷酸的步骤（S160）。 （附图标记）（AA）开始; （BB）结束; （S110）在固体支持物上提供具有寡核苷酸复制文库的测序分析底物; （S120）顺序复制库; （S130）获取实体支持的实际位置信息; （S140）映射像素信息和实际位置信息; （S150）使用映射结果提取固体支持; （S160）通过扩增提取的固体支持物的寡核苷酸大量复制
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公开(公告)号：KR1020110034072A
公开(公告)日：2011-04-05
申请号：KR1020090091441
申请日：2009-09-28
Applicant: 서울대학교산학협력단
IPC: G02B5/00
CPC classification number: G02B5/02 , G02B19/0023 , G02B19/0066 , G02B27/09 , H01L33/50 , H01L33/58 , H01L2924/0002 , H05B33/10 , H05B33/14 , H01L2924/00
Abstract: PURPOSE: A composite film for a light emitting device, the light emitting device, and a manufacturing method thereof are provided to improve energy efficiency by using a high brightness LED as a light source. CONSTITUTION: A composite film(1820) is used in a light emitting device(1800) including a light emitting element(1830). A fluorescent layer includes a fluorescent element. An optical plate is arranged on the fluorescent layer and diffuses, reduces, or mixes light radiated by the fluorescent layer and the mixture thereof.
Abstract translation: 目的：提供一种用于发光器件的复合膜，发光器件及其制造方法，以通过使用高亮度LED作为光源来提高能量效率。 构成：在包括发光元件（1830）的发光器件（1800）中使用复合膜（1820）。 荧光层包括荧光元件。 在荧光层上设置光学板，并且扩散，减少或混合由荧光层辐射的光及其混合物。
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