公开(公告)号：ZA8206832B

公开(公告)日：1983-08-31

申请号：ZA8206832

申请日：1982-09-17

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  MUELLER JOSEF ,  LIETZ HELMUT ,  WIERSDORFF WALTER WIELANT ,  HEGE HANS GUENTHER ,  MUELLER CLAUS D ,  GRIES JOSEF ,  LENKE DIETER ,  PHILIPSBORN GERDA VON ,  RASCHACK MANFRED

IPC: A61K31/135 ,  A61K20060101 ,  A61K31/40 ,  A61K31/445 ,  A61K31/495 ,  A61K31/535 ,  A61K31/5375 ,  A61P9/06 ,  C07C20060101 ,  C07C67/00 ,  C07C213/00 ,  C07C217/36 ,  C07C225/22 ,  C07C323/25 ,  C07D207/06 ,  C07D211/44 ,  C07D211/52 ,  C07D295/08 ,  A61K ,  C07C

公开(公告)号：DD201795A5

公开(公告)日：1983-08-10

申请号：DD23843782

申请日：1982-03-25

Applicant: BASF AG

Inventor： BINNIG FRITZ ,  MUELLER CLAUS D ,  RASCHACK MANFRED ,  PHILIPSBORN GERDA VON

IPC: A61K31/435 ,  A61K31/445 ,  A61P9/00 ,  A61P9/06 ,  C07D221/00 ,  C07D471/08

Abstract: Bispidine derivatives of the formula I I where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.

公开(公告)号：ZA8202416B

公开(公告)日：1983-03-30

申请号：ZA8202416

申请日：1982-04-08

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETSZSCHMAR ROLF ,  LEHMANN HANS DIETER ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS JOERG ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS GEORG ,  MUELLER CLAUS D

IPC: A61K31/275 ,  A61K20060101 ,  A61K31/335 ,  A61K31/357 ,  A61K31/36 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/12 ,  A61P37/08 ,  C07C20060101 ,  C07C67/00 ,  C07C253/00 ,  C07C255/42 ,  C07C313/00 ,  C07C323/25 ,  C07C323/62 ,  C07D317/58 ,  C07D319/08 ,  C07D319/18 ,  A61K ,  C07C

公开(公告)号：CA1135705A

公开(公告)日：1982-11-16

申请号：CA332072

申请日：1979-07-18

Applicant: BASF AG

Inventor： BLIESENER JENS-UWE ,  GEISS KARL-HEINZ ,  LENKE DIETER ,  MUELLER CLAUS D

IPC: A61K31/40 ,  C07D207/48 ,  C07D307/68 ,  C07D333/28 ,  C07D333/38 ,  C07D405/12 ,  C07D409/12 ,  C07D403/12

Abstract: Disclosed are compound of the formula 1 wherein R1 is alkyl of 2 to 5 carbon atom, alkyl, benzyl, furylmethyl wherein the furan ring may be substituted by bromine or thienylmethyl wherein the thiophene ring may he monosubstituted by a methyl and R2 is hydrogen or R1 and R2 together with the nitrogen form a pyrrolidine ring R3 is hydrogen, methyl or ethyl R4 and R5 are hydrogen ox R4 is methyl or ethyl in the .alpha.-position of the pyrrole ring and R5 in methyl, ethyl or Npropyl in the .alpha.-position of the pyrrole ring X is oxygen, sulfur or and Ar in phenyl that may be substituted by chlorine, and their therapeutically useful ammonium salts, alkali metal salts or acid addition salts, which compounds and salts thereof exhibit valuable pharmacological properties, their preperation, therapeutic agents containing these products, and their use as drugs.

公开(公告)号：NO803047A

公开(公告)日：1981-04-14

申请号：NO803047

申请日：1980-10-10

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER ,  FRANKE ALBRECHT ,  PHILIPSBORN GERDA VON ,  MUELLER CLAUS D ,  LENKE DIETER

IPC: A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/454 ,  A61K31/47 ,  A61P9/00 ,  A61P9/06 ,  C07C271/22 ,  C07D207/34 ,  C07D207/36 ,  C07D209/42 ,  C07D401/12 ,  C07D401/14 ,  C07D

CPC classification number: C07D209/42 ,  C07C271/22 ,  C07D207/36 ,  Y10S514/821