公开(公告)号：KR1020100006605A

公开(公告)日：2010-01-21

申请号：KR1020080066789

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P25/06 ,  A61P25/00

Abstract: PURPOSE: A composition containing dried powder of sand lance fraction or its extract is provided to suppress pain using an animal model by inducing acetic acid pain test, heat plate and tail flick test. CONSTITUTION: A pharmaceutical composition for preventing and treating pain contains dried powder or its extract of sand lance fraction as an active ingredient. The extract of sand lance fraction is obtained by heating the sand lance fraction at 60°C-150°C for 12 to 48 hours. The pain is the headache, toothache, backache, burn ache, neuralgia, period pains or arthralgia. The pharmaceutical composition contains 0.1-50 weight% of the dried powder or its extract based on the total weight.

Abstract translation: 目的：提供一种含有喷沙部分或其提取物的干粉的组合物，通过诱导乙酸疼痛试验，加热板和尾巴轻弹试验，通过动物模型抑制疼痛。 构成：用于预防和治疗疼痛的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 通过在60℃-150℃下加热沙枪级分12至48小时获得沙枪分数的提取物。 疼痛是头痛，牙痛，背痛，疼痛，神经痛，周期痛或关节痛。 该药物组合物含有0.1-50重量％的干燥粉末或其提取物，基于总重量。

公开(公告)号：KR1020100006602A

公开(公告)日：2010-01-21

申请号：KR1020080066786

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing dried powder or its extract of sand lance fraction is provided to reduce total cholesterol and triglyceride in blood. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of dried powder of sand lance fraction or its extract as an active ingredient. The sand lance is obtained from East sea, Japan, Sakhalin island, Okhotsk Sea, or Pacific and Atlantic. The dried powder is obtained through freeze-drying or sun drying. A functional health food for preventing and treating hyperlipidemia contains the dried powder or its extract as an active ingredient. The functional health food is used in the form of tablet, capsule, pill or liquid.

Abstract translation: 目的：提供含有干粉或其提取物的沙枪成分的组合物，以减少血液中的总胆固醇和甘油三酯。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的干燥粉末的沙枪部分或其提取物作为活性成分。 沙枪从东海，日本，萨哈林岛，鄂霍次克海，太平洋和大西洋获得。 干燥后的粉末通过冷冻干燥或晒干得到。 用于预防和治疗高脂血症的功能性保健食品含有干粉或其提取物作为活性成分。 功能保健食品以片剂，胶囊，丸剂或液体的形式使用。

公开(公告)号：KR1020100006604A

公开(公告)日：2010-01-21

申请号：KR1020080066788

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P29/00

Abstract: PURPOSE: A composition containing dried powder or its fraction of sand lance fraction is provided to suppress inflammation in an animal model insuding serotonin, carrageenin, and FCA(freund's complete adjuvant). CONSTITUTION: A pharmaceutical composition for preventing and treating inflammation contains dried powder or its fraction of sand lance fraction as an active ingredient. The sand lance is from near East sea, Japan, Sakhalin island, and Okhotsk Sea or Pacific and Atlantic. The pharmaceutical composition is used in the form of powder, granule, tablet, capsule, suspension, syrup, suppository, or sterilization injection solution.

Abstract translation: 目的：提供含有干燥粉末或其部分的喷沙部分的组合物，以抑制血清素，角叉菜胶和FCA（弗氏完全佐剂）的动物模型中的炎症。 构成：用于预防和治疗炎症的药物组合物含有干粉或其作为活性成分的沙枪级分。 沙枪来自东海，日本，萨哈林岛，鄂霍次克海，太平洋和大西洋。 药物组合物以粉末，颗粒剂，片剂，胶囊，悬浮液，糖浆剂，栓剂或灭菌注射液的形式使用。

公开(公告)号：KR1020100006603A

公开(公告)日：2010-01-21

申请号：KR1020080066787

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P19/02

Abstract: PURPOSE: A composition containing dried powder or extract of sand lance fraction is provided to suppress inflammation in animal model and ensure high suppression effect for arthritis in CRP(C-reactive protein) test. CONSTITUTION: A pharmaceutical composition for preventing and treating arthritis contains dried powder or its extract of sand lance fraction as an active ingredient. A method for producing the dried powder of sand lance fraction comprises: a step of washing sand lance to remove foreign materials and salt; a step of cutting the sand lance to skin, intestines, eggs, head, fin, fish bone, cartilage, muscle, eye and gill; and a step of drying through freezing and under the sun.

Abstract translation: 目的：提供含有干粉或沙矛提取物的组合物，以抑制动物模型中的炎症，并确保CRP（C反应蛋白）测试中关节炎的高抑制作用。 构成：用于预防和治疗关节炎的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 一种生产干燥喷砂干燥粉末的方法，包括：清洗喷砂以除去异物和盐的步骤; 将沙枪切割成皮肤，肠，蛋，头，鳍，鱼骨，软骨，肌肉，眼睛和鳃的一个步骤; 以及通过冷冻和在阳光下干燥的步骤。