公开(公告)号：KR1020100006605A

公开(公告)日：2010-01-21

申请号：KR1020080066789

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P25/06 ,  A61P25/00

Abstract: PURPOSE: A composition containing dried powder of sand lance fraction or its extract is provided to suppress pain using an animal model by inducing acetic acid pain test, heat plate and tail flick test. CONSTITUTION: A pharmaceutical composition for preventing and treating pain contains dried powder or its extract of sand lance fraction as an active ingredient. The extract of sand lance fraction is obtained by heating the sand lance fraction at 60°C-150°C for 12 to 48 hours. The pain is the headache, toothache, backache, burn ache, neuralgia, period pains or arthralgia. The pharmaceutical composition contains 0.1-50 weight% of the dried powder or its extract based on the total weight.

Abstract translation: 目的：提供一种含有喷沙部分或其提取物的干粉的组合物，通过诱导乙酸疼痛试验，加热板和尾巴轻弹试验，通过动物模型抑制疼痛。 构成：用于预防和治疗疼痛的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 通过在60℃-150℃下加热沙枪级分12至48小时获得沙枪分数的提取物。 疼痛是头痛，牙痛，背痛，疼痛，神经痛，周期痛或关节痛。 该药物组合物含有0.1-50重量％的干燥粉末或其提取物，基于总重量。

公开(公告)号：KR1020100006599A

公开(公告)日：2010-01-21

申请号：KR1020080066783

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  남정숙 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing dried powder and extract of chub mackerel fraction is provided to reduce total cholesterol and blood triglyceride content. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of dried powder or extract of chub mackerel fraction as an active ingredient. The fraction of the chub mackerel is head, cartilage, shell, muscle, eye, gill, total body of the fish. A method for preparing the dried powder of chub mackerel fraction comprises: a step of washing and removing foreign material and salt from the chub mackerel; and a step of cutting head, cartilage, shell, muscle, eye, gill, and total body. The extract is isolated using water, alcohol and spirit extract solvent.

Abstract translation: 目的：提供含有干粉的组合物和鲭鱼and提取物，以降低总胆固醇和血甘油三酯含量。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的干燥粉末或作为活性成分的鲭鱼片提取物。 小鲭鱼的分数是头，软骨，壳，肌肉，眼睛，鳃，鱼的全身。 一种制备鲭鱼m the干燥粉末的方法，包括：从鲭鱼鲭鱼中洗涤除去异物和盐的步骤; 并切割头，软骨，壳，肌肉，眼睛，鳃和全身的一个步骤。 使用水，酒精和精油提取物溶剂分离提取物。

公开(公告)号：KR101021718B1

公开(公告)日：2011-03-15

申请号：KR1020080067215

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  진현정 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: 본 발명은 꽁치 분획 건조 분말 또는 그 추출물을 유효성분으로 함유하는 조성물에 관한 것으로서, 구체적으로 본 발명의 꽁치 분획 건조 분말 또는 그 추출물은 고지혈증 동물모델의 혈중 중성지방 및 혈중 총 콜레스테롤 함량의 감소 효과를 나타냄으로써, 고지혈증의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용될 수 있다.
꽁치, 분획 건조 분말, 추출물, 혈중 중성지방, 혈중 총 콜레스테롤, 고지혈증

公开(公告)号：KR1020100006895A

公开(公告)日：2010-01-22

申请号：KR1020080067216

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  진현정 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P35/00 ,  A61P3/10

Abstract: PURPOSE: A composition containing pacific saury-dried fraction or its extract is provided to reduce oxygen free radical and malodialdehyde(MDA) and ensure SOD(superoxide dismutase) activity. CONSTITUTION: A pharmaceutical composition for preventing and treating oxidation-related diseases contains pacific saury fraction dried powder or its extract as an active ingredient. The pacific saury fraction dried powder is obtained by: washing the pacific saury, removing foreign material and salt; cutting the pacific saury to intestines, whole body, bone, cartilage, skin, muscle, eye and gills; and performing vacuum-drying or light drying of the fractions. The extract of the pacific saury fraction is obtained by grinding or pulverizing the fractions and extracting with water, alcohol or spirit. The oxidation-related diseases is cancer, diabetes, hepatitis, gastritis, nephritis, carditis, rheumatoid arthritis, heart disease, AIDS, cataract or dermatome.

Abstract translation: 目的：提供含有太平洋西番莲干组分或其提取物的组合物，以减少氧自由基和malodialdehyde（MDA），并确保SOD（超氧化物歧化酶）活性。 构成：用于预防和治疗氧化相关疾病的药物组合物含有太平洋刀屑级干粉或其提取物作为活性成分。 太平洋切碎干粉是通过以下方法获得的：洗涤太平洋刀，去除异物和盐; 切割太平洋刀对肠，全身，骨，软骨，皮肤，肌肉，眼睛和鳃; 并对该级分进行真空干燥或轻度干燥。 通过研磨或粉碎级分并用水，酒精或精油提取，可获得太平洋刀鱼馏分的提取物。 氧化相关疾病是癌症，糖尿病，肝炎，胃炎，肾炎，心脏炎，类风湿性关节炎，心脏病，艾滋病，白内障或皮肤病。

公开(公告)号：KR1020100006604A

公开(公告)日：2010-01-21

申请号：KR1020080066788

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P29/00

Abstract: PURPOSE: A composition containing dried powder or its fraction of sand lance fraction is provided to suppress inflammation in an animal model insuding serotonin, carrageenin, and FCA(freund's complete adjuvant). CONSTITUTION: A pharmaceutical composition for preventing and treating inflammation contains dried powder or its fraction of sand lance fraction as an active ingredient. The sand lance is from near East sea, Japan, Sakhalin island, and Okhotsk Sea or Pacific and Atlantic. The pharmaceutical composition is used in the form of powder, granule, tablet, capsule, suspension, syrup, suppository, or sterilization injection solution.

Abstract translation: 目的：提供含有干燥粉末或其部分的喷沙部分的组合物，以抑制血清素，角叉菜胶和FCA（弗氏完全佐剂）的动物模型中的炎症。 构成：用于预防和治疗炎症的药物组合物含有干粉或其作为活性成分的沙枪级分。 沙枪来自东海，日本，萨哈林岛，鄂霍次克海，太平洋和大西洋。 药物组合物以粉末，颗粒剂，片剂，胶囊，悬浮液，糖浆剂，栓剂或灭菌注射液的形式使用。

公开(公告)号：KR1020100006603A

公开(公告)日：2010-01-21

申请号：KR1020080066787

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P19/02

Abstract: PURPOSE: A composition containing dried powder or extract of sand lance fraction is provided to suppress inflammation in animal model and ensure high suppression effect for arthritis in CRP(C-reactive protein) test. CONSTITUTION: A pharmaceutical composition for preventing and treating arthritis contains dried powder or its extract of sand lance fraction as an active ingredient. A method for producing the dried powder of sand lance fraction comprises: a step of washing sand lance to remove foreign materials and salt; a step of cutting the sand lance to skin, intestines, eggs, head, fin, fish bone, cartilage, muscle, eye and gill; and a step of drying through freezing and under the sun.

Abstract translation: 目的：提供含有干粉或沙矛提取物的组合物，以抑制动物模型中的炎症，并确保CRP（C反应蛋白）测试中关节炎的高抑制作用。 构成：用于预防和治疗关节炎的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 一种生产干燥喷砂干燥粉末的方法，包括：清洗喷砂以除去异物和盐的步骤; 将沙枪切割成皮肤，肠，蛋，头，鳍，鱼骨，软骨，肌肉，眼睛和鳃的一个步骤; 以及通过冷冻和在阳光下干燥的步骤。

公开(公告)号：KR100840547B1

公开(公告)日：2008-06-23

申请号：KR1020070044353

申请日：2007-05-08

Applicant: 강릉원주대학교산학협력단

Inventor： 박신호 ,  김옥선 ,  조순영 ,  김광우 ,  김정식 ,  김혜경 ,  안효영 ,  허길원

IPC: A23L1/20 ,  A23L1/29

CPC classification number: A23L11/07 ,  A23L33/10 ,  A23P10/22 ,  A23V2002/00 ,  A23V2250/511

Abstract: A preparation method of a bean curd product using beta-chitosan is provided to obtain high-quality functional bean curd with enhanced solidity, elasticity and texture. A preparation method of a bean curd product using beta-chitosan comprises the steps of: (i) washing soybeans and soaking them in water at 10~30°C for 5~15hr; (ii) drying the soaked soybeans, adding distilled water to the dried soybeans, and grinding them; (iii) filtering the ground soybeans with cotton cloth, mixing distilled water heated to 95~100°C with the filtered ground soybeans, and filtering the mixture to make soybean milk; (iv) raising the temperature of the soybean milk to 95~100°C, putting 5~20% of brine containing beta-chitosan into the soybean milk (based on the total volume of the soybean milk), and stirring them to make a coagulated soybean milk; (v) putting the coagulated soybean milk in a mold, and pressing it for 15~25min to make bean curd; and (vi) soaking the bean curd in running water for 15~25min, and laying it on a drying rack for 10~20min to remove the water on its surface. In the step (ii), the volume ratio of the dried soybeans and the distilled water is 1:8~10. In the step (iii), the volume ratio of the filtered ground soybeans and the heated distilled water is 1:3~5. In the step (iv), the brine contains 0.05~2% of beta-chitosan(1000~5000kDa), based on the total volume of the brine.

Abstract translation: 提供使用β-壳聚糖的豆腐制品的制备方法，以获得具有增强的坚固性，弹性和质地的高品质功能性豆腐。 使用β-壳聚糖的豆腐制品的制备方法包括以下步骤：（i）洗涤大豆并在10〜30℃的水中浸泡5〜15小时; （ii）干燥浸泡的大豆，向干燥的大豆中加入蒸馏水并研磨; （iii）用棉布过滤磨碎的大豆，将加热至95〜100℃的蒸馏水与过滤的大豆混合物过滤，过滤混合物制成豆浆; （iv）将豆浆的温度升高至95〜100℃，将5〜20％的含有β-壳聚糖的盐水放入豆浆中（基于豆浆的总体积），并搅拌使其成为 凝结豆浆; （v）将凝固的豆浆放入模具中，压制15〜25min，制成豆腐; 和（vi）将豆腐浸泡在自来水中15〜25分钟，放置在干燥架上10〜20分钟以除去水面。 在步骤（ii）中，干燥的大豆和蒸馏水的体积比为1:8〜10。 在步骤（iii）中，过滤的大豆和加热的蒸馏水的体积比为1:3〜5。 在步骤（iv）中，基于盐水的总体积，盐水含有0.05〜2％的β-壳聚糖（1000〜5000kDa）。

公开(公告)号：KR1020100023395A

公开(公告)日：2010-03-04

申请号：KR1020080082126

申请日：2008-08-22

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P9/10

Abstract: PURPOSE: A composition containing salmon fraction-dried powder or extract thereof is provided to suppress total cholesterol content and to prevent and treat arteriosclerosis. CONSTITUTION: A pharmaceutical composition for preventing and treating arteriosclerosis contains 0.1-50 weight% of salmon fraction-dried powder or extract thereof as an active ingredient. The fraction is obtained by dividing salmon body, intestine, head, fin, bone, cartilage, muscle, eye or gill. A method for manufacturing the salmon fraction-dried powder comprise: a first step of washing salmon and removing salinity and foreign materials; a second step of cutting salmon to obtain fraction; and a third step of freeze-drying fraction and pulverizing.

Abstract translation: 目的：提供含有鲑鱼馏分干燥粉末或其提取物的组合物以抑制总胆固醇含量并预防和治疗动脉硬化。 构成：用于预防和治疗动脉硬化的药物组合物含有0.1-50重量％的鲑鱼馏分干燥粉末或其提取物作为活性成分。 该分数通过分割鲑鱼体，肠，头，鳍，骨，软骨，肌肉，眼睛或鳃获得。 制造鲑鱼馏分干燥粉末的方法包括：洗涤鲑鱼并除去盐度和异物的第一步骤; 切割三文鱼以获得分数的第二步; 和冷冻干燥级分并粉碎的第三步骤。

公开(公告)号：KR1020100023394A

公开(公告)日：2010-03-04

申请号：KR1020080082125

申请日：2008-08-22

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing salmon fraction-dried powder or extract thereof is provided to suppress the content of neutral fat in blood and to prevent and treat hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of salmon fraction-dried powder or extract thereof as an active ingredient. The salmon fraction is divided to whole salmon body, intestine, head, bone, cartilage, gill and muscle. The daily dosage of active ingredient is 0.0001-100 mg/kg. A functional health food for preventing and treating hyperlipidemia contains the salmon fraction-dried powder or extract thereof as an active ingredient. The food is used in the form of beverage, tablet, capsule, pill or liquor.

Abstract translation: 目的：提供含有三文鱼馏分干燥粉末或其提取物的组合物以抑制血液中的中性脂肪含量，并预防和治疗高脂血症。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的鲑鱼馏分干燥粉末或其提取物作为活性成分。 鲑鱼分为整个鲑鱼体，肠，头，骨，软骨，鳃和肌肉。 活性成分的日剂量为0.0001〜100mg / kg。 用于预防和治疗高脂血症的功能性保健食品含有作为活性成分的鲑鱼馏分干燥粉末或其提取物。 食物以饮料，片剂，胶囊，药丸或酒的形式使用。

公开(公告)号：KR1020100006894A

公开(公告)日：2010-01-22

申请号：KR1020080067215

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  진현정 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing pacific saury-fraction dried powder or its extract is provided to reduce total cholesterol content in blood and blood triglycerides. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains pacific saury-fraction dried powder or its extract as an active ingredient. A pacific saury fraction is obtained from total body of the pacific saury, head, bone, fin, skin, cartilage, eye, and gill. A functional health food for preventing and treating hyperlipidemia contains pacific saury-fraction dried powder or its extract as an active ingredient. The health food is used in the form of tablet, capsule, pill or liquid.

Abstract translation: 目的：提供含有太平刀柄级干粉或其提取物的组合物，以降低血液和血液中甘油三酯的总胆固醇含量。 构成：用于预防和治疗高脂血症的药物组合物含有作为活性成分的太平洋刀片级干粉或其提取物。 太平洋刀鱼部分是从太平洋刀刀，头，骨，鳍，皮肤，软骨，眼睛和鳃的全身中获得的。 用于预防和治疗高脂血症的功能性保健食品含有太平洋刀状干粉或其提取物作为活性成分。 保健食品以片剂，胶囊，丸剂或液体的形式使用。