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1.发明公开톳을 유효성분으로 함유하는 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료용 조성물 有权包含HIZIKIA FUSIFORMIS用于预防和治疗肥胖或高胆固醇血症和血管性血管疾病的组合物
公开(公告)号：KR1020120016962A
公开(公告)日：2012-02-27
申请号：KR1020100079519
申请日：2010-08-17
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing Hizikia fusiformis is provided to reduce neutral fat, cholesterol, phospholipid, and hydroxyl radical in serum. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity or hyperlipidemia and ateriosclerotic vascualr diseases contains Hizikia fusiformis as an active ingredient. The Hizikia fusiformis is used in the form of dry powder, polar solvent soluble extract, or polar solvent insoluble extract. A health food for preventing and treating obesity or hyperlipidemia and ateriosclerotic vascualr diseases contains Hizikia fusiformis as an active ingredient. The health food is manufactured in the form of powder, granules, tablets, capsules, or drink.
Abstract translation: 目的：提供含有尖吻containing丝虫的组合物，以减少血清中的中性脂肪，胆固醇，磷脂和羟基自由基。 构成：用于预防和治疗肥胖症或高脂血症和硬膜外血管病变的药物组合物含有丝状contains丝菌作为活性成分。 Hizikia fusiformis以干粉，极性溶剂可溶性提取物或极性溶剂不溶性提取物的形式使用。 一种用于预防和治疗肥胖症或高脂血症和硬膜外血管病变的健康食品含有丝状假丝酵母作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊或饮料的形式制造。
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2.发明公开양미리 분획 건조 분말 또는 그 추출물을 유효성분으로함유하는 통증질환의 예방 및 치료용 조성물 无效包含干燥粉末的砂糖（HYPOPTYCHUS DYBOWSKII）的组合物或其提取物，用于预防和治疗疼痛疾病
公开(公告)号：KR1020100006605A
公开(公告)日：2010-01-21
申请号：KR1020080066789
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing dried powder of sand lance fraction or its extract is provided to suppress pain using an animal model by inducing acetic acid pain test, heat plate and tail flick test. CONSTITUTION: A pharmaceutical composition for preventing and treating pain contains dried powder or its extract of sand lance fraction as an active ingredient. The extract of sand lance fraction is obtained by heating the sand lance fraction at 60°C-150°C for 12 to 48 hours. The pain is the headache, toothache, backache, burn ache, neuralgia, period pains or arthralgia. The pharmaceutical composition contains 0.1-50 weight% of the dried powder or its extract based on the total weight.
Abstract translation: 目的：提供一种含有喷沙部分或其提取物的干粉的组合物，通过诱导乙酸疼痛试验，加热板和尾巴轻弹试验，通过动物模型抑制疼痛。 构成：用于预防和治疗疼痛的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 通过在60℃-150℃下加热沙枪级分12至48小时获得沙枪分数的提取物。 疼痛是头痛，牙痛，背痛，疼痛，神经痛，周期痛或关节痛。 该药物组合物含有0.1-50重量％的干燥粉末或其提取物，基于总重量。
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公开(公告)号：KR1020100006599A
公开(公告)日：2010-01-21
申请号：KR1020080066783
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing dried powder and extract of chub mackerel fraction is provided to reduce total cholesterol and blood triglyceride content. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of dried powder or extract of chub mackerel fraction as an active ingredient. The fraction of the chub mackerel is head, cartilage, shell, muscle, eye, gill, total body of the fish. A method for preparing the dried powder of chub mackerel fraction comprises: a step of washing and removing foreign material and salt from the chub mackerel; and a step of cutting head, cartilage, shell, muscle, eye, gill, and total body. The extract is isolated using water, alcohol and spirit extract solvent.
Abstract translation: 目的：提供含有干粉的组合物和鲭鱼and提取物，以降低总胆固醇和血甘油三酯含量。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的干燥粉末或作为活性成分的鲭鱼片提取物。 小鲭鱼的分数是头，软骨，壳，肌肉，眼睛，鳃，鱼的全身。 一种制备鲭鱼m the干燥粉末的方法，包括：从鲭鱼鲭鱼中洗涤除去异物和盐的步骤; 并切割头，软骨，壳，肌肉，眼睛，鳃和全身的一个步骤。 使用水，酒精和精油提取物溶剂分离提取物。
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公开(公告)号：KR1020080094983A
公开(公告)日：2008-10-28
申请号：KR1020070039157
申请日：2007-04-23
Applicant: 강릉원주대학교산학협력단
Abstract: Cuttlebone powder or an extract thereof is provided to inhibit gastrointestinal ulcer, thereby being used as a pharmaceutical composition and a health functional food for preventing and treating gastrointestinal diseases. A method for preparing an extract of a cuttlebone comprises the steps of: (a) drying and crushing the cuttlebone to obtain cuttlebone powder; (b) after reacting the cuttlebone powder with about 1-30 times of water, an aqueous solution of NaOH or an aqueous solution of HCl at a temperature of 20-100 deg.C for about 1-24 hour(s), separating a reaction solution and remnants; and (c) after neutralizing and desalinating the reaction solution, concentrating and freeze-drying it. A pharmaceutical composition for preventing or treating gastrointestinal diseases comprises 0.1-50 wt.% of the cuttlebone powder or the extract thereof as an effective ingredient. A health functional food for preventing and improving the gastrointestinal diseases comprises the powder of cuttlebone or the extract thereof as an effective ingredient. The health functional food is in a form of a granule, a tablet, a capsule, a syrup or a drink.
Abstract translation: 提供乌龟粉或其提取物以抑制胃肠溃疡，从而用作药物组合物和用于预防和治疗胃肠道疾病的健康功能食品。 一种制备粉刺提取物的方法，包括以下步骤：（a）干燥并粉碎cut骨以获得粉碎粉末; （b）在将粉刺粉末与约1-30倍的水，NaOH水溶液或HCl水溶液在20-100℃的温度下反应约1-24小时后，分离 反应液和残留物; 和（c）中和和脱盐反应溶液后，浓缩并冷冻干燥。 用于预防或治疗胃肠道疾病的药物组合物包含0.1-50重量％的粉碎粉末或其提取物作为有效成分。 用于预防和改善胃肠道疾病的健康功能食品包括粉刺粉或其提取物作为有效成分。 健康功能食品是颗粒，片剂，胶囊，糖浆或饮料的形式。
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公开(公告)号：KR101373493B1
公开(公告)日：2014-03-14
申请号：KR1020100079519
申请日：2010-08-17
Applicant: 강릉원주대학교산학협력단
Abstract: 본 발명은 톳을 유효성분으로 함유하는 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 상세하게는 본 발명의 톳은 고지혈증을 유발시킨 동물모델에서 간조직 및 분변 중 지질 함량을 감소시키고, 혈청 중의 중성지방, 콜레스테롤, 인지질, 과산화지질 및 Hydroxyl radical 함량을 감소시키며, 혈청 중 SOD 활성을 증진시킴을 확인한 바, 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료에 유용한 약학조성물 및 건강기능식품에 이용될 수 있다.
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Patent Agency Ranking6.发明授权홍게를 유효성분으로 함유하는 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료용 조성물 失效包含用于预防和治疗肥胖或高脂血症和动脉粥样硬化血管疾病的Chioneceter japonicur的组合物
公开(公告)号：KR101203752B1
公开(公告)日：2012-11-21
申请号：KR1020100079520
申请日：2010-08-17
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/612 , A23L1/30 , A23L17/40
Abstract: 본 발명은 홍게를 유효성분으로 함유하는 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 상세하게는 본 발명의 홍게는 고지혈증을 유발시킨 동물모델에서 간조직 및 분변 중 지질 함량을 감소시키고, 혈청 중의 중성지방, 콜레스테롤, 인지질, 과산화지질 및 Hydroxyl radical 함량을 감소시키며, 혈청 중 SOD 활성을 증진시킴을 확인한 바, 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료에 유용한 약학조성물 및 건강기능식품에 이용될 수 있다.
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7.发明公开미역을 유효성분으로 함유하는 비만 또는 고지혈증 및 동맥경화성 혈관계 질환의 예방 및 치료용 조성물 无效包含UNDARIA PINNATIFIDA（GARNEY）SURINGAR的组合物，用于预防和治疗肥胖或高血脂和脑血管病变血管疾病
公开(公告)号：KR1020120016961A
公开(公告)日：2012-02-27
申请号：KR1020100079518
申请日：2010-08-17
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing Undaria pinnatifida for preventing and treating obesity or hyperlipidemia is provided to reduce lipid content in liver and feces. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity or hyperlipidemia and arteriosclerotic vascular diseases contains Undaria pinnatifida as an active ingredient. A method for manufacturing polar solvent insoluble extract of Undaria pinnatifida comprises: a step of pulverizing dry Undaria pinnatifida and adding water, methanol, ethanol, butanol, and mixture thereof; a step of extracting at 1°C-50°C for 10-50 minutes by sonication, reflux extraction, hot water extraction, freeze-extraction, or supercritical extraction; a step of filtering the extract; and a step of concentrating at 5°C to 45°C and freeze-drying at -5°C to -60°C.
Abstract translation: 目的：提供含有用于预防和治疗肥胖或高脂血症的Undaria pinnatifida的组合物，以减少肝脏和粪便中的脂质含量。 构成：用于预防和治疗肥胖症或高脂血症和动脉硬化性血管疾病的药物组合物含有作为活性成分的芒果（Undaria pinnatifida）。 一种制备黑曲霉的极性溶剂不溶性提取物的方法，其特征在于，包括：将干燥的pin of粉碎并加入水，甲醇，乙醇，丁醇及其混合物的步骤; 通过超声处理，回流提取，热水提取，冷冻提取或超临界萃取在1℃-50℃提取10-50分钟的步骤; 过滤提取物的步骤; 和在5℃至45℃下浓缩并在-5℃至-60℃冷冻干燥的步骤。
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8.发明授权꽁치 분획 건조 분말 또는 그 추출물을 유효성분으로함유하는 고지혈증의 예방 및 치료용 조성물 失效一种组合物，其包含用于预防和治疗高脂血症的SauryColoabis saira级分的干燥粉末或其提取物
公开(公告)号：KR101021718B1
公开(公告)日：2011-03-15
申请号：KR1020080067215
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: 본 발명은 꽁치 분획 건조 분말 또는 그 추출물을 유효성분으로 함유하는 조성물에 관한 것으로서, 구체적으로 본 발명의 꽁치 분획 건조 분말 또는 그 추출물은 고지혈증 동물모델의 혈중 중성지방 및 혈중 총 콜레스테롤 함량의 감소 효과를 나타냄으로써, 고지혈증의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용될 수 있다.
꽁치, 분획 건조 분말, 추출물, 혈중 중성지방, 혈중 총 콜레스테롤, 고지혈증-
公开(公告)号：KR1020100056142A
公开(公告)日：2010-05-27
申请号：KR1020080115166
申请日：2008-11-19
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition for preventing and treating arteriosclerosis containing Pacific herring fraction dry powder or extract is provided to reduce total cholesterol content in blood. CONSTITUTION: A pharmaceutical composition for preventing and treating arteriosclerosis contains 0.1-50 weight% of Pacific herring fraction dry powder or extract as an active ingredient. The extract is isolated using water, low alcohol of 1-4 carbon atoms, or mixture solvent. A health food for preventing and treating artheriosclerosis contains Pacific herring fraction dry powder or extract as an active ingredient. The health food is used in the form of powder, granule, capsule, or beverage.
Abstract translation: 目的：提供一种用于预防和治疗含有太平洋鲱鱼级干粉或提取物的动脉硬化的组合物，以减少血液中的总胆固醇含量。 构成：用于预防和治疗动脉硬化的药物组合物含有0.1-50重量％的太平洋鲱鱼级干粉或提取物作为活性成分。 使用水，1-4碳原子的低级醇或混合溶剂分离提取物。 用于预防和治疗动物硬化症的保健食品含有太平洋鲱鱼级干粉或提取物作为活性成分。 保健食品以粉末，颗粒，胶囊或饮料的形式使用。
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公开(公告)号：KR1020100056141A
公开(公告)日：2010-05-27
申请号：KR1020080115165
申请日：2008-11-19
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing Pacific herring fraction dry powder or extract is provided to redue neutral fat content in blood and to prevent and treat hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidermia contains Pacific herring fraction dry powder or extract as an active ingredient. The Pacific herring fraction is obtained from total body of the Pacific herring, muscle, intestine, head, bone, cartilage, skin, eye, and gill. The Pacific herring fraction is isolated using water, low alcohol of 1-4 carton atoms, or mixture solvent.
Abstract translation: 目的：提供含有太平洋鲱鱼级干粉或提取物的组合物，以减少血液中的中性脂肪含量并预防和治疗高脂血症。 构成：用于预防和治疗高脂血症的药物组合物含有太平洋鲱鱼级干粉或提取物作为活性成分。 太平洋鲱鱼分数是从太平洋鲱鱼，肌肉，肠，头，骨，软骨，皮肤，眼睛和鳃的全身获得的。 太平洋鲱鱼分数使用水，1-4巴原子的低醇或混合溶剂分离。
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