公开(公告)号：WO2019164080A1

公开(公告)日：2019-08-29

申请号：PCT/KR2018/012111

申请日：2018-10-15

Applicant: 강원도 ,  진기환

Inventor： 진기환 ,  박영식 ,  엄남용 ,  정햇님 ,  방순배 ,  이제창

IPC: B05B12/02 ,  A01G3/00 ,  B05B9/04 ,  B05B12/00 ,  A01G7/06 ,  B05B12/08

Abstract: 과수 적화용 분사장치가 개시된다. 일 실시예는, 모터와, 모터에 연결되는 압축부와, 압축부에 형성된 인입구 및 인출구를 구비한 공압발생부; 상기 공압발생부의 인입구에 연결되어 물을 공급하는 물공급관과, 상기 물공급관이 연결된 수조로 구성된 물공급부; 상기 공압발생부의 인출구에 연결되어 고압의 물을 배출하는 물배출관과, 상기 물배출관에 연결되며 고압의 물을 멈춤과 직분사를 반복하도록 개폐작동을 간헐적으로 실행하여 수압을 증폭시키는 수압조절부; 상기 수압조절부의 온오프 작동을 제어하는 스위치; 상기 수압조절부에 연결되어 고압의 물을 분사하는 분사용 건;을 포함한다.

公开(公告)号：KR101960048B1

公开(公告)日：2019-03-20

申请号：KR1020180071662

申请日：2018-06-21

Applicant: 강원도

Inventor： 박영식 ,  엄남용 ,  정햇님 ,  방순배 ,  이제창

IPC: A01G3/00 ,  B05B9/03

公开(公告)号：KR101150870B1

公开(公告)日：2012-06-13

申请号：KR1020110059001

申请日：2011-06-17

Applicant: 강원도

Inventor： 임상현 ,  김희연 ,  이광재 ,  정햇님 ,  김경희 ,  박유화 ,  함헌주 ,  김성문

IPC: A61K36/185 ,  A61K31/575 ,  A61P29/00

CPC classification number: A61K36/185 ,  A61K31/575 ,  A61K2236/33 ,  A61K2236/55

Abstract: PURPOSE: A method for isolating beta-sitosterol from Hippophae rhamnoides L. stems is provided to obtain a therapeutic agent for treating various inflammatory diseases including arthritis. CONSTITUTION: A method for isoalting beta-sitosterol from Hippophae rhamnoides L. stems comprises: a step of dipping dry Hippophae rhamnoides L. stems in ethanol and applying ultrasonic wave; a step of collecting supernatant to prepare ethanol extract; a step of adding distilled water and hexane to the ethanol extract and collecting supernatant to prepare a hexane fraction; a step of adding dichloromethane to prepare a dichloromethane fraction; a step of adding ethyl acetate to upper layer isolated from the solution to prepare an ethyl acetate fraction; a step of adding butanol to a lower layer isolated from the solution containing ethyl acetate to prepare a butanol fraction; a step of preparing a distilled water fraction from the solution; a step of mixing the hexane fraction, dichloromethane fraction, ethyl acetate fraction, butanol fraction, and distilled water fraction to prepare a mixture fraction; and a step of performing middle pressure liquid chromatography of the mixture fraction using a first solution containing hexane, dichloromethane, ethyl acetate and butanol and a second solution containing methanol.

Abstract translation: 目的：提供一种从沙棘沙门氏杆菌分离β-谷甾醇的方法，以获得治疗各种炎症性疾病（包括关节炎）的治疗剂。 构成：从沙棘沙门氏菌中分离β-谷甾醇的方法包括：将干燥的沙棘沙门氏菌浸在乙醇中并施加超声波的步骤; 收集上清液制备乙醇提取物的步骤; 向乙醇提取物中加入蒸馏水和己烷并收集上清液以制备己烷级分的步骤; 加入二氯甲烷以制备二氯甲烷组分的步骤; 向从溶液中分离的上层加入乙酸乙酯制备乙酸乙酯级分的步骤; 将丁醇加入到从含有乙酸乙酯的溶液中分离的下层以制备丁醇级分的步骤; 从溶液中制备蒸馏水部分的步骤; 将己烷馏分，二氯甲烷馏分，乙酸乙酯馏分，丁醇馏分和蒸馏水馏分混合以制备混合物馏分的步骤; 以及使用含有己烷，二氯甲烷，乙酸乙酯和丁醇的第一溶液和含有甲醇的第二溶液进行混合级分的中压液相色谱的步骤。

公开(公告)号：KR102029990B1

公开(公告)日：2019-10-08

申请号：KR1020180019935

申请日：2018-02-20

Applicant: 강원도 ,  주식회사 케이보배

Inventor： 박영식 ,  엄남용 ,  정햇님 ,  방순배 ,  이제창 ,  진기환

IPC: A01G3/00 ,  A01G7/06 ,  B05B12/02 ,  B05B12/08 ,  B05B9/04

公开(公告)号：KR1020110049252A

公开(公告)日：2011-05-12

申请号：KR1020090106184

申请日：2009-11-04

Applicant: 강원도

Inventor： 임상현 ,  김희연 ,  이광재 ,  정햇님 ,  김경희 ,  박유화 ,  함헌주 ,  김성문

IPC: C07J9/00 ,  A61K31/57 ,  C12P33/16 ,  A61P31/00

CPC classification number: C07J9/00 ,  A23L33/10 ,  A61K8/63 ,  A61K31/575 ,  A61Q19/00

Abstract: PURPOSE: A separation method of beta-sitosterol from trunks of hippophae rhamnoides, and an anti-inflammatory activity composition containing the beta-sitosterol are provided to use the anti-inflammatory activity composition as a therapeutic agent for arthritis. CONSTITUTION: A separation method of beta-sitosterol from trunks of hippophae rhamnoides comprises the following steps: applying ethanol to the bark of the dried trunks of the hippophae rhamnoides, for obtaining the ethanol extract of the trunks of the hippophae rhamnoides; adding distilled water and hexane to the ethanol extract for separating an upper layer and a lower layer from the solution containing the hexane; separating an upper layer and a lower layer from a solution containing dichloromethane; collecting the lower layer from the solution containing the dichloromethane, for obtaining dichloromethane fractions; and separating the beta-sitosterol from the dichloromethane fractions using the medium pressure liquid chromatography.

Abstract translation: 目的：提供沙棘沙门氏菌的β-谷甾醇分离方法和含有β-谷甾醇的抗炎活性组合物，以使用抗炎活性组合物作为关节炎的治疗剂。 构成：沙棘沙门氏菌β-谷甾醇的分离方法包括以下步骤：将乙醇施用于沙棘干燥树干的树皮中，以获得沙门氏菌的树干的乙醇提取物; 向乙醇提取物中加入蒸馏水和己烷，从含有己烷的溶液中分离上层和下层; 从含有二氯甲烷的溶液中分离上层和下层; 从含有二氯甲烷的溶液中收集下层，以获得二氯甲烷馏分; 并使用中压液相色谱法从二氯甲烷馏分中分离出β-谷甾醇。

公开(公告)号：KR102101330B1

公开(公告)日：2020-04-17

申请号：KR1020180023038

申请日：2018-02-26

Applicant: 강원도

Inventor： 박영식 ,  엄남용 ,  정햇님 ,  방순배 ,  이제창

IPC: B05B12/02 ,  A01G3/00 ,  B05B9/04 ,  B05B12/00

公开(公告)号：KR100812652B1

公开(公告)日：2008-03-13

申请号：KR1020060105949

申请日：2006-10-30

Applicant: 강원도

Inventor： 조수현 ,  최병곤 ,  김경희 ,  임상현 ,  정햇님

IPC: A23F3/00 ,  A23L1/212 ,  A23F3/16 ,  A23F3/30

Abstract: Tea-bag type tea containing the stems and leaves of Eleutherococcus senticosus and its preparation method are provided to enable consumers to take the useful ingredients of Eleutherococcus senticosus easily by roasting the stems and leaves. Tea-bag type tea containing the stems and leaves of Eleutherococcus senticosus is prepared by the steps of: (i) drying the stems or leaves of Eleutherococcus senticosus to the water content of 5~15%, roasting the dried stems or leaves at 210~250‹C for 5~25min, pulverizing the roasted stems or leaves into 1~5mm, roasting bean and corn at 210‹C for 10~25min and pulverizing them into 150mum~1mm, and pulverizing apple into 150mum~1mm; and (ii) mixing 50~70% of the roasted leaves, 20~40% of the roasted stems, 5~15% of side ingredients(0.5~10% of each of the apple, bean and corn), and then making tea-bag type tea with Eleutherococcus senticosus by using a tea-bag packer.

Abstract translation: 提供含有Eleutherococcus senticosus的茎叶的茶袋式茶及其制备方法，使消费者能够通过烘烤茎叶轻松摄取洋葱Eleutherococcus的有用成分。 通过以下步骤制备含有Eleutherococcus senticosus的茎叶的茶袋型茶：（i）将Ele草的茎或叶干燥至含水量为5〜15％，烘干干茎或叶为210〜 250℃烘烤5〜25分钟，将烤茎或叶片粉碎成1〜5mm，在210℃焙烧玉米10〜25分钟，粉碎成150m〜1mm，将苹果粉碎成150μm〜1mm; 和（ii）混合50〜70％的烤叶，20〜40％的烤茎，5〜15％的副成分（0.5〜10％的苹果，豆和玉米），然后制作茶 通过使用茶包封隔器，具有Eleutherococcus senticosus的袋式茶。

公开(公告)号：KR100812651B1

公开(公告)日：2008-03-13

申请号：KR1020060105948

申请日：2006-10-30

Applicant: 강원도

Inventor： 조수현 ,  최병곤 ,  김경희 ,  임상현 ,  정햇님

IPC: A23F3/00 ,  A23F3/16 ,  A23L1/212 ,  A23F3/12

Abstract: Granular tea containing an Eleutherococcus senticosus extract and its preparation method are provided to minimize the loss of useful ingredients contained in Eleutherococcus senticosus, and to produce functional foods using the Eleutherococcus senticosus. Granular tea containing an Eleutherococcus senticosus extract is prepared by the steps of: (i) drying the stem or root of Eleutherococcus senticosus for the water content to be 5~15%, and roasting the dried stem or root at 210~250‹C for 5~25min; (ii) performing a first extraction at 90~100‹C for 5~6hr by adding water to the roasted stem or root in a weight ratio of 25~30:1, performing a second extraction at 80~90‹C for 3~4hr by adding water to the roasted stem or root in a weight ratio of 8~10:1, and performing extraction at 90~100‹C for 3~4hr by adding water to undried and grinded fruit in a weight ratio of 20~25:1; and (iii) mixing 7~11% of the stem extract(15Brix or so), 2~6% of the root extract(15Brix or so), 1~3% of the fruit extract(15Brix or so), and 85% of sugar, and then making granular tea with Eleutherococcus senticosus by using a granule-making machine.

Abstract translation: 本发明提供了含有十字花科提取物的颗粒茶及其制备方法，以减少二十一肠球菌中含有的有用成分的损失，并使用埃氏弧菌产生功能性食品。 通过以下步骤制备含有洋葱提取物的颗粒茶：（i）将水分含量为5〜15％，将干燥的茎或根干燥至210〜250℃， 5〜25分钟; （ii）通过以25〜30：1的重量比将水添加到烤茎或根中，在90〜100℃下进行5〜6小时的第一次提取，在80〜90℃下进行3〜 4小时通过向烤茎或根中加入水，重量比为8〜10：1，并在90〜100℃下通过向未干燥和研磨的水果中加入水，重量比为20〜25，提取3〜4小时 ：1; 和（iii）将7-11％的茎提取物（15Brix等），2〜6％的根提取物（15Brix等），1〜3％的果实提取物（15Brix左右）和85％ 的糖，然后通过使用颗粒制造机制造具有Eleutherococcus senticosus的颗粒状茶。