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公开(公告)号：KR101744339B1
公开(公告)日：2017-06-08
申请号：KR1020100041383
申请日：2010-05-03
Applicant: 삼성전자주식회사 , 아주대학교산학협력단
IPC: G01N33/543 , G01N27/447 , G01N29/02 , G01N29/036 , G01N1/40
CPC classification number: G01N33/54373 , G01N27/44717 , G01N29/022 , G01N29/036 , G01N2001/4038 , G01N2291/0255 , G01N2291/0256
Abstract: 타겟생체분자의분리요소를포함하는표면탄성파센서디바이스에관한것으로서, 타겟생체분자를포함하는샘플을전기영동을통해크기로분리한후 SAW 센서에순차적으로반응시킨다. 즉, 전기영동을이용하여생체분자를분리시킨후, 분리된생체분자를대상으로 SAW 센서에적용시켜타겟생체분자를검출할수 있는장치이다.
Abstract translation: 涉及一种表面声波传感器装置，其包括靶标生物分子的分离元件，所述样品包含靶生物分子，然后通过电泳按大小分离，并依次反应，以SAW传感器。 也就是说，使用电泳分离生物分子，然后分离生物分子并将其应用于SAW传感器以检测目标生物分子。
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公开(公告)号：KR1020110121884A
公开(公告)日：2011-11-09
申请号：KR1020100041383
申请日：2010-05-03
Applicant: 삼성전자주식회사 , 아주대학교산학협력단
IPC: G01N33/543 , G01N27/447 , G01N29/02 , G01N29/036 , G01N1/40
CPC classification number: G01N33/54373 , G01N27/44717 , G01N29/022 , G01N29/036 , G01N2001/4038 , G01N2291/0255 , G01N2291/0256 , G01N27/447
Abstract: PURPOSE: A surface acoustic wave sensor device having a target bimolecular isolation component is provided to separate various biomolecules according to size using an electrophoresis apparatus. CONSTITUTION: A surface acoustic wave sensor device having a target bimolecular isolation component comprises a separation element and a surface acoustic wave sensor. The separation element separates biomolecules(200) using an electrophoresis method. The biomolecules have the same or different sizes as/from a target biomolecule. A receptor(300) is attached on the surface acoustic wave sensor and is coupled to the target biomolecule.
Abstract translation: 目的：提供具有目标双分子分离组分的表面声波传感器装置，以使用电泳装置根据尺寸分离各种生物分子。 构成：具有目标双分子隔离成分的表面声波传感器装置包括分离元件和声表面波传感器。 分离元件使用电泳方法分离生物分子（200）。 生物分子具有与靶生物分子相同或不同的大小。 受体（300）附着在表面声波传感器上，并与目标生物分子结合。
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公开(公告)号：KR101490377B1
公开(公告)日：2015-02-05
申请号：KR1020080042704
申请日：2008-05-08
Applicant: 삼성전자주식회사
IPC: A61B5/00
CPC classification number: G01N33/54373 , G01N29/022 , G01N29/036 , G01N33/6854 , G01N2291/012 , G01N2291/015 , G01N2291/0255 , G01N2291/0256 , G01N2291/0423 , G01N2800/24
Abstract: 하나의 알레르기 원인물질로부터 유래된 알레르겐(allergen)이 고정되어 있고, 타(他) 알레르기 원인물질로부터 유래된 알레르겐은 포함하지 않고, 각각 별개의 알레르기 원인물질로부터 유래된 알레르겐이 고정된 하나 이상의 표면탄성파(SAW)소자; 및 상기 표면탄성파 소자로부터의 출력 신호를 검출하는 신호 검출기를 포함하는 알레르기 질환 진단용 표면탄성파 센서가 개시된다. 또한, 상기 센서를 이용하여 여러 종류의 알레르기 원인물질로부터 유래된 알레르겐들에 각각 특이적으로 결합하는 IgE 양 및 총 IgE 양을 진단대상의 혈액 등의 샘플로부터 측정함으로써, 여러 종류의 알레르기 원인물질에 대하여 효과적으로 알레르기를 진단할 수 있는 알레르기 질환의 진단방법이 개시된다. 본 발명의 일실시예에 의한 표면탄성파 센서 및 진단방법을 이용하면, 피부단자검사로 인해 발생할 수 있는 통증 수반 및 과민반응에 의한 쇼크(Anaphylaxis) 발생을 방지할 수 있고, 저렴하고 간편하게, 높은 정확도 및 감도로 알레르기 진단을 할 수 있다.
표면탄성파, SAW, 센서, 알레르기, IgE, 알레르겐, 면역질환-
4.发明公开광 조사에 의한 금 나노입자의 질량 강화 방법, 이를 이용한 생체분자 결합 검출 방법 및 바이오센서 无效通过照相光照增强金纳米粒子的方法，用于使用增强质量的方法检测生物分子结合的方法和生物传感器的方法
公开(公告)号：KR1020120094259A
公开(公告)日：2012-08-24
申请号：KR1020110013641
申请日：2011-02-16
Applicant: 삼성전자주식회사 , 포항공과대학교 산학협력단
CPC classification number: G01N33/54373 , B82Y15/00 , B82Y30/00 , B82Y40/00 , G01N33/54346
Abstract: PURPOSE: A mass reinforcing method of gold nano-particles due to light irradiation, a biosensor, and biomolecule combining detection method using the same are provided to reinforce mass of the gold nano-particles by using an optical irradiation method. CONSTITUTION: A mass reinforcing method of gold nano-particles due to light irradiation comprises the following steps: irradiating a mixture including gold nano-particles(13) and reinforcing metal component(15) with light; and increasing the mass of the gold nano-particles by reducing thereof on the surface of the gold nano-particles. The light is ultraviolet ray. The metal reinforcing component is metallic ion. A bio molecular combining detection method comprises the following steps: reacting target bio molecular with bio sensors which detect physical property changes according to bondage of the target bio molecular; combining the gold nano-particle to the target bio molecular; dipping the bio sensor into a mixture which includes the metal reinforcing components and irradiating light; and detecting physical property change of the gold nano-particles.
Abstract translation: 目的：提供由光照射引起的金纳米颗粒的质量增强方法，生物传感器和使用其的生物分子组合检测方法，以通过使用光学照射方法来增强金纳米颗粒的质量。 构成：由于光照射而导致的金纳米颗粒的质量增强方法包括以下步骤：用光照射包含金纳米颗粒（13）和增强金属成分（15）的混合物; 并且通过在金纳米颗粒的表面上还原金纳米颗粒的质量来增加金纳米颗粒的质量。 光线是紫外线。 金属增强部件是金属离子。 生物分子组合检测方法包括以下步骤：使靶生物分子与生物传感器反应，根据目标生物分子的结合检测物理性质变化; 将金纳米颗粒与目标生物分子结合; 将生物传感器浸入包括金属增强组分和照射光的混合物中; 并检测金纳米粒子的物理性质变化。
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公开(公告)号：KR1020120080117A
公开(公告)日：2012-07-16
申请号：KR1020110077364
申请日：2011-08-03
Applicant: 삼성전자주식회사
Abstract: PURPOSE: A biosensor cartridge for automating entire process for detecting a biogenic substance is provided to enable cheap and highly efficient detection and to enhance detection accuracy. CONSTITUTION: A biosensor cartridge(100) comprises: a plasma separator(110) for isolating plasma from blood; a plasma measuring unit(120) for measuring and storing the plasma isolated from the plasma separator; a mixer(150,152) for storing a sample to detecting a biogenic substance from plasma and mixing the plasma and sample; and a biosensor(180) which is injected to the mixture liquid of the plasma and sample and is used for detecting the biogenic substance in the plasma.
Abstract translation: 目的：提供用于自动化用于检测生物物质的整个过程的生物传感器盒，以便廉价且高效地检测并提高检测精度。 构成：生物传感器盒（100）包括：用于从血液中分离血浆的等离子体分离器（110） 等离子体测量单元（120），用于测量和存储从等离子体分离器隔离的等离子体; 用于存储样品以从血浆中检测生物来源物质并混合血浆和样品的混合器（150,152） 和注射到血浆和样品的混合液中的生物传感器（180），用于检测血浆中的生物物质。
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Patent Agency Ranking
公开(公告)号：KR1020120061579A
公开(公告)日：2012-06-13
申请号：KR1020100122926
申请日：2010-12-03
Applicant: 삼성전자주식회사
IPC: B01L3/00
CPC classification number: B01L3/502761 , B01L2300/0816 , B01L2300/0851 , B01L2400/086 , Y10T436/25 , Y10T436/25375
Abstract: PURPOSE: A hydrodynamic filter and a filtering apparatus are provided to continuously filter target molecules. CONSTITUTION: A hydrodynamic filter(100) comprises a first part(10) and a second part(20) which separately faces the first part. The first part comprises a plurality of protrusions(30,40) protruded in a first side direction. The second part has a plurality of protrusions(35,45). The first and second parts are formed of silicon-based polymers or polymer materials. The protrusion part of the first part has first and second protrusion parts. The protrusion part of the second part comprises third and fourth protrusion parts separately formed each other. The distance between the first and third protrusion parts is 1-50 um.
Abstract translation: 目的：提供流体动力过滤器和过滤装置，以连续过滤目标分子。 构成：流体动力学过滤器（100）包括分开面对第一部分的第一部分（10）和第二部分（20）。 第一部分包括沿第一侧面方向突出的多个突起（30,40）。 第二部分具有多个突起（35,45）。 第一和第二部分由硅基聚合物或聚合物材料形成。 第一部分的突出部分具有第一和第二突出部分。 第二部分的突出部分包括彼此分开形成的第三和第四突出部分。 第一和第三突出部分之间的距离为1-50μm。
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公开(公告)号：KR1020120006591A
公开(公告)日：2012-01-19
申请号：KR1020100067146
申请日：2010-07-13
Applicant: 삼성전자주식회사
CPC classification number: G01N29/222 , G01N29/022 , Y10S436/807 , Y10T29/49826
Abstract: PURPOSE: A sensor for bubble preventive fluid is provided to improve detection sensitivity improvement and reliability and to minimize noise. CONSTITUTION: A sensor for bubble preventive fluid comprises a main body member(111), a reactive part(130), an inlet part(140) and an outlet part(150). The main body member comprises a substrate(110) accomplishing a lower part and a top plate(120) accomplishing an upper side. The fluid sample reacts in the reactive part as the internal space of the main body member. The inlet part locates in one side of the top plate. The inlet part flows in the fluid sample as a reactive part. The outlet part locates in the other side of the top plate. The outlet part flows out the fluid sample from the reactive part.
Abstract translation: 目的：提供防泡液体传感器，以提高检测灵敏度，提高可靠性并降低噪音。 构成：用于防泡液体的传感器包括主体构件（111），反作用部分（130），入口部分（140）和出口部分（150）。 主体构件包括实现下部的基板（110）和实现上侧的顶板（120）。 流体样品在反应部分中作为主体构件的内部空间反应。 入口部分位于顶板的一侧。 入口部分作为反应部分流入流体样品。 出口部分位于顶板的另一侧。 出口部分从反应部分流出流体样品。
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公开(公告)号：KR1020100069945A
公开(公告)日：2010-06-25
申请号：KR1020080128506
申请日：2008-12-17
Applicant: 삼성전자주식회사
Abstract: PURPOSE: An allergy diagnosis system using cross reaction probability is provided to digitalize cross-reactivity probability and to reduce test cost. CONSTITUTION: A method for diagnosing allergy using cross reaction probability to allergy test result comprises: a step of extracting epitope region sequence containing allergy causing material; a step of extracting candidate sequence which has structural similarity with the extracted epitope sequence from database; a step of detecting candidate-derived allergy causing material; a step of calculating a first cross reaction probability; a step of calculating second cross reaction probability; and a step of diagnosing allergy as the degree of the first and second cross reaction probability.
Abstract translation: 目的：提供使用交叉反应概率的过敏诊断系统，以数字化交叉反应概率并降低测试成本。 构成：使用交叉反应概率对过敏试验结果诊断过敏的方法包括：提取含有过敏原材料的表位区序列的步骤; 从数据库中提取与提取的表位序列具有结构相似性的候选序列的步骤; 检测候选导致过敏原材料的步骤; 计算第一交叉反应概率的步骤; 计算第二交叉反应概率的步骤; 并且将过敏诊断的步骤作为第一和第二交叉反应概率的程度。
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公开(公告)号：KR1020090116901A
公开(公告)日：2009-11-12
申请号：KR1020080042704
申请日：2008-05-08
Applicant: 삼성전자주식회사
IPC: A61B5/00
CPC classification number: G01N33/54373 , G01N29/022 , G01N29/036 , G01N33/6854 , G01N2291/012 , G01N2291/015 , G01N2291/0255 , G01N2291/0256 , G01N2291/0423 , G01N2800/24
Abstract: PURPOSE: An SAW(Surface Acoustic Wave) immunosensor for diagnosing allergy disease and a method for diagnosing allergy disease using the same are provided to effectively diagnose allergy about various allergy cause materials by measuring IgE amount through a change of an SAW signal. CONSTITUTION: An SAW immunosensor for diagnosing allergy disease includes an SAW device, a reference SAW device, a signal detector, and a comparing part. One or more allergens from one allergy cause material are fixed to the SAW device. The SAW device does not include allergy from a different allergy cause material. The signal detector detects an output signal from the SAW device. The allergen is not fixed to the reference SAW device. The comparing part compares an output signal from the reference SAW device with the output signal from the SAW device.
Abstract translation: 目的：提供用于诊断过敏疾病的SAW（表面声波）免疫传感器和使用该过敏疾病诊断过敏疾病的方法，以通过改变SAW信号来测量IgE量来有效地诊断关于各种过敏原因物质的过敏。 构成：用于诊断过敏疾病的SAW免疫传感器包括SAW器件，参考SAW器件，信号检测器和比较部件。 来自一种过敏原因的一种或多种过敏原固定在SAW器件上。 SAW装置不包括来自不同过敏原因的过敏。 信号检测器检测来自SAW器件的输出信号。 过敏原不固定在参考的SAW器件上。 比较部分将来自参考SAW器件的输出信号与来自SAW器件的输出信号进行比较。
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公开(公告)号：KR100876158B1
公开(公告)日：2008-12-31
申请号：KR1020070105495
申请日：2007-10-19
Applicant: 삼성전자주식회사
Abstract: An apparatus device for detecting a bio molecule using piezoelectric sensor is provided to prevents errors from being generated by a change of a temperature and a change of a pressure of a surrounding environment because the change of the temperature and the change of the pressure identically have an effect on the piezoelectric sensor of a sensor unit and a piezoelectric sensor of a trigger signal occurrence portion. An apparatus device for detecting a bio molecule contains sensor units(10,20) measuring number of clock signal of oscillation signals generated according to pressure that biomasses compress to the piezoelectric materials, an operation unit(40) for calculating an amount of the biomass according to the number of the clock signals and a trigger signal occurrence portion(30) generating the trigger signal.
Abstract translation: 提供了一种使用压电传感器检测生物分子的设备装置，以防止由于温度变化和周围环境压力变化而产生误差，因为温度的变化和压力变化相同地具有 作用于传感器单元的压电传感器和触发信号发生部分的压电传感器。 一种用于检测生物分子的设备装置包括：传感器单元（10,20），用于测量根据生物体压缩到压电材料的压力产生的振荡信号的时钟信号的数量;操作单元（40），用于根据生物量 与时钟信号的数量以及产生触发信号的触发信号发生部分（30）。
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