-
公开(公告)号：KR101455901B1
公开(公告)日：2014-11-03
申请号：KR1020120047766
申请日：2012-05-04
Applicant: 성균관대학교산학협력단
IPC: A61K9/08 , A61K47/48 , A61K31/44 , A61K31/404
CPC classification number: A61K47/10 , A61K31/635 , A61K47/40
Abstract: 본 발명은 난용성 약물인 세레콕시브에 폴록사머를 첨가하여 공융 현상을 일으킴으로써, 용해도 및 생체이용률이 현저하게 증가된 세레콕시브를 제공하는 공융 혼합물에 관한 것이다.
-
公开(公告)号：KR1020130134353A
公开(公告)日：2013-12-10
申请号：KR1020120057807
申请日：2012-05-30
Applicant: 성균관대학교산학협력단
IPC: A61K9/14 , A61P1/04 , A61K31/4704
CPC classification number: A61K9/143 , A61K9/146 , A61K31/4704 , Y10S514/925
Abstract: The present invention relates to a pharmaceutical solid dispersion formulation for treatment of an ulcer and a preparing method thereof and, more particularly, to a pharmaceutical solid dispersion formulation for treatment of ulcer, capable of improving drug solubility and bioavailability, containing rebamipide, a water-soluble polymer, and a non-ionic surfactant. Thus, the present invention provides a method for preparing a solid dispersion formulation having improved drug solubility and bioavailability, so that the pharmaceutical formulation can have improved efficacy and thus be used for effective treatment of ulcer. [Reference numerals] (AA) Ulcer area(mm^2);(BB) Control group
Abstract translation: 本发明涉及用于治疗溃疡的药物固体分散体制剂及其制备方法，更具体地涉及能够改善药物溶解度和生物利用度的药物固体分散体制剂，其可用于治疗溃疡，其包含瑞巴派特， 可溶性聚合物和非离子表面活性剂。 因此，本发明提供了制备具有改进的药物溶解度和生物利用度的固体分散体制剂的方法，使得药物制剂可以具有改善的功效，因此用于有效治疗溃疡。 （AA）溃疡面积（mm ^ 2）;（BB）对照组
-
公开(公告)号：KR1020130003602A
公开(公告)日：2013-01-09
申请号：KR1020110065045
申请日：2011-06-30
Applicant: 성균관대학교산학협력단
CPC classification number: A61K9/1652 , A61K9/1617 , A61K9/1682 , A61K31/145 , A61K47/38
Abstract: PURPOSE: A sustained release microparticle composition containing tamsulosin, ethyl cellulose, and enteric polymer is provided to ensure sustained release and enteric properties. CONSTITUTION: A sustained release microparticle composition contains tamsulosin or a pharmaceutically acceptable salt thereof, ethyl cellulose, and enteric polymers. The enteric polymers are hydroxypropylmethyl cellulosephthalate, hydroxypropylmethyl cellulose acetatesuccinate, or methacrylic acid-acrylic acid ethyl copolymers. [Reference numerals] (AA) Released amount of medicine; (BB) Time(minutes); (CC) Comparative embodiment 4; (DD) Comparative embodiment 5; (EE) Embodiment 1; (FF) Embodiment 2; (GG) Embodiment 3
Abstract translation: 目的：提供含有坦索罗辛，乙基纤维素和肠溶性聚合物的持续释放微粒组合物，以确保持续释放和肠溶性。 构成：缓释微粒组合物含有坦索罗辛或其药学上可接受的盐，乙基纤维素和肠溶聚合物。 肠溶性聚合物是羟丙基甲基纤维素邻苯二甲酸酯，羟丙基甲基纤维素乙酸丁二酸酯或甲基丙烯酸 - 丙烯酸乙基共聚物。 （附图标记）（AA）药物释放量; （BB）时间（分钟）; （CC）比较实施例4; （DD）比较实施例5; （EE）实施例1; （FF）实施例2; （GG）实施例3
-
公开(公告)号：KR1020140075662A
公开(公告)日：2014-06-19
申请号：KR1020140063999
申请日：2014-05-27
Applicant: 성균관대학교산학협력단
CPC classification number: A61K47/34 , A61K31/635
Abstract: The present invention relates to a eutectic composition comprising celecoxib and poloxamer. The eutectic composition comprising celecoxib and poloxamer according to one embodiment of the present invention includes celecoxib or pharmaceutically acceptable salt and block copolymer of poly (polyoxyethylene) and poly (Polyoxypropylene) and is manufactured by thermal melting.
Abstract translation: 本发明涉及包含塞来昔布和泊洛沙姆的共晶组合物。 根据本发明一个实施方案的包含塞来昔布和泊洛沙姆的共晶组合物包括塞来昔布或其可药用盐和聚（聚氧乙烯）和聚（聚氧丙烯）的嵌段共聚物，并且通过热熔制造。
-
公开(公告)号：KR1020130124113A
公开(公告)日：2013-11-13
申请号：KR1020120047766
申请日：2012-05-04
Applicant: 성균관대학교산학협력단
IPC: A61K9/08 , A61K47/48 , A61K31/44 , A61K31/404
CPC classification number: A61K47/10 , A61K31/635 , A61K47/40 , A61K9/08 , A61K31/404 , A61K31/44 , A61K47/50
Abstract: The present invention relates to an eutectic mixture having celecoxib with remarkably enhanced solubility and bioavailability through an eutetic reaction by adding poloxamer of chemical formula 2 to celecoxib of chemical formula 1 which is an insoluble drug. The weight ratio of poloxamer with respect to celecoxib is 3:7-6:4. More preferably, the eutectic mixture according to the present invention contains 1.5 parts by weight of poloxamer with respect to 1 part by weight of celecoxib. [Reference numerals] (AA) Temperature ;(BB) % celecoxib
Abstract translation: 本发明涉及一种具有塞来昔布的共晶混合物，其通过将化学式2的泊洛沙姆加入作为不溶性药物的化学式1的塞来昔布，通过可口反应显着提高溶解性和生物利用度。 泊洛沙姆相对于塞来昔布的重量比为3：7-6：4。 更优选地，根据本发明的共晶混合物相对于1重量份的塞来昔布含有1.5重量份泊洛沙姆。 （参考号）（AA）温度;（BB）％塞来昔布
-
Patent Agency Ranking
公开(公告)号：KR1020130037802A
公开(公告)日：2013-04-17
申请号：KR1020110102243
申请日：2011-10-07
Applicant: 성균관대학교산학협력단
IPC: A61K9/28 , A61K31/428 , A61K47/38
CPC classification number: A61K9/28 , A61K9/2866 , A61K31/428 , A61K47/38
Abstract: PURPOSE: A sustained release fine particle containing pramipexole and a composition containing the same are provided to ensure a release-controlling effect by additional coating of ethyl cellulose. CONSTITUTION: A composition is a release-controlled formulation which is prepared by coating a sustained release fine particle containing pramipexole or a salt thereof with a coating solution containing ethyl cellulose. The sustained release fine particle contains pramipezole or a salt thereof and hydroxypropyl methylcellulose. [Reference numerals] (AA) Elution rate(%); (BB) Time(h); (CC) Bead weight ratio of before coating : after coating = 1 : 1.5; (DD) Bead weight ratio of before coating : after coating = 1 : 1.3;
Abstract translation: 目的：提供含有普拉克索的缓释微粒和含有它们的组合物，以通过额外涂布乙基纤维素来确保释放控制效果。 构成：组合物是通过用含有乙基纤维素的涂布溶液涂布含有普拉克索或其盐的缓释微粒制备的释放控制制剂。 持续释放的微粒含有丙胺嘧啶或其盐和羟丙基甲基纤维素。 （AA）洗脱率（％） （BB）时间（h）; （CC）涂布前的珠重比：涂布后= 1：1.5; （DD）涂布前的珠重比：涂布后= 1：1.3;
-
7.发明公开히드록시프로필메틸셀룰로오스를 이용한 레보카바스틴 함유 나노현탁액의 제조방법 및 이로부터 제조된 레보카바스틴 함유 나노현탁액 无效通过使用羟丙基甲基纤维素制备含有左氧氟沙星的纳米颗粒的方法和制备含有左旋巴比妥的纳米抗体
公开(公告)号：KR1020130037770A
公开(公告)日：2013-04-17
申请号：KR1020110102182
申请日：2011-10-07
Applicant: 성균관대학교산학협력단
IPC: A61K9/10 , A61K47/38 , A61K31/445 , A61K9/00
CPC classification number: A61K9/10 , A61K9/0048 , A61K31/445 , A61K47/38
Abstract: PURPOSE: A method for preparing levocabastine-containing nanosuspension using hydroxypropyl methylcellulose is provided to enhance drug solubility by redispersion of a solid dispersant in an aqueous phase. CONSTITUTION: A method for preparing levocabastine-containing nanosuspension using hydroypropyl methylceullose comprises: a step of dissolving levocabastine and hydroxypropyl methylcellulose in a solvent and preparing a solid dispersant; and a step of dispersing the solid dispersant. The levocabastine is levocabastine hydrochloride. [Reference numerals] (AA) Particle size(nm); (BB) Example 1; (CC) Example 2; (DD) Example 3; (EE) Comparative example 1; (FF) Comparative example 2; (GG) Comparative example 3;
Abstract translation: 目的：提供使用羟丙基甲基纤维素制备含有左卡巴斯汀的纳米悬浮液的方法，以通过将固体分散剂再分散在水相中来增强药物的溶解度。 构成：使用羟丙基甲基菊糖制备含有左卡巴斯汀的纳米悬浮液的方法包括：将左卡巴斯坦和羟丙基甲基纤维素溶解在溶剂中并制备固体分散剂的步骤; 和分散固体分散剂的步骤。 左卡巴斯汀是盐酸左卡巴斯坦。 （标号）（AA）粒径（nm） （BB）实施例1; （CC）实施例2; （DD）实施例3; （EE）比较例1; （FF）比较例2; （GG）比较例3;
-
8.发明公开증강현실기법을 이용한 건축 구조물 정보 제공 장치, 건축 구조물 디스플레이 장치 및 이를 이용한 건축 구조물 유지 보수 방법 有权用于提供建筑结构信息的装置和使用具有现实意义的建筑结构显示和使用该建筑结构维护建筑结构的方法
公开(公告)号：KR1020120020303A
公开(公告)日：2012-03-08
申请号：KR1020100083843
申请日：2010-08-30
Applicant: 성균관대학교산학협력단
IPC: G06T17/00
CPC classification number: G06T19/006 , G06T7/344 , G06T17/05 , G06T2210/04
Abstract: PURPOSE: A device for providing a building structure using an augmented reality technique, a building structure display device, and a building structure maintaining method using the same are provided to supply a 3D design for a building structure by augmented images. CONSTITUTION: A transceiving unit(210) transceives an image of a construction site or a building structure of the construction site. A design searching unit(220) searches the building structure and a 3D design for the building structure. An image processing unit(230) overlaps the searched 3D design with the images of the construction site or the building structure using an augmented reality technique.
Abstract translation: 目的：提供一种使用增强现实技术提供建筑结构的装置，建筑结构显示装置和使用其的建筑结构维护方法，以通过增强图像为建筑结构提供3D设计。 规定：收发单元（210）收集施工现场的图像或施工现场的建筑结构。 设计搜索单元（220）搜索建筑结构和建筑结构的3D设计。 图像处理单元（230）使用增强现实技术将所搜索的3D设计与施工现场的图像或建筑结构重叠。
-
公开(公告)号：KR1020110104374A
公开(公告)日：2011-09-22
申请号：KR1020100023482
申请日：2010-03-16
Applicant: 성균관대학교산학협력단
IPC: A61K9/16 , A61K9/32 , A61K47/36 , A61K31/425
CPC classification number: A61K9/1652 , A61K9/1658 , A61K9/167 , A61K9/1682 , A61K31/428 , Y10S514/97
Abstract: 본 발명은 저장 안정성이 높은 프라미펙솔 디하이드로클로라이드(pramipexole dihydrochloride) 정제 및 이의 제조방법을 제공하기 위한 것이다.
-
10.发明授权증강현실기법을 이용한 건축 구조물 정보 제공 장치, 건축 구조물 디스플레이 장치 및 이를 이용한 건축 구조물 유지 보수 방법 有权用于提供建筑结构信息的装置和使用具有现实意义的建筑结构显示和使用该建筑结构维护建筑结构的方法
公开(公告)号：KR101171264B1
公开(公告)日：2012-08-06
申请号：KR1020100083843
申请日：2010-08-30
Applicant: 성균관대학교산학협력단
IPC: G06T17/00
Abstract: 증강현실기법을 이용한 건축 구조물 정보 제공 장치는 건설 현장(site) 또는 건설 현장에 위치한 건축 구조물의 영상을 수신하는 송수신부, 건설 현장에 건설될 건축 구조물 또는 건설 현장에 위치한 건축 구조물에 대응되는 3D 설계도를 검색하는 설계도 검색부 및 증강현실기법을 이용하여 검색된 3D 설계도를 건설 현장 또는 건설 현장에 위치한 건축 구조물의 영상에 중첩하는 영상 처리부를 포함한다.
-
-
-
-
-
-
-
-
-
Search Results
13
records
(took 0.021 seconds)
