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公开(公告)号：KR100623322B1
公开(公告)日：2006-09-19
申请号：KR1020040088413
申请日：2004-11-02
Applicant: 신풍제약주식회사
IPC: A61K31/357
CPC classification number: A61K31/357 , A61K31/4375 , Y02A50/411 , A61K2300/00
Abstract: 본 발명은 약제학적으로 허용되는 담체와 함께, 유효성분으로서 알테미시닌(artemisinine) 또는 그의 유도체 및 피로나리딘(pyronaridine) 또는 그의 염을 포함하는, 경구투여용 항말라리아 제제에 관한 것이다.
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公开(公告)号：KR1020050107640A
公开(公告)日：2005-11-15
申请号：KR1020040032630
申请日：2004-05-10
Applicant: 신풍제약주식회사
Abstract: 본 발명은 구인(룸브리쿠스 루벨루스(
Lumbricus rubellus ))의 조추출물을 수용성 유기용매로 분별침전(fractional precipitation)하고 초여과(ultrafiltration)하는 단계를 포함하여, 항혈전 및 혈전용해 활성을 갖는 단백질분해효소(protease) 분말을 제조하는 방법에 관한 것이다.-
公开(公告)号：KR1020090083848A
公开(公告)日：2009-08-04
申请号：KR1020090001655
申请日：2009-01-08
Applicant: 신풍제약주식회사
IPC: C07D239/96 , A61K31/517 , A61P25/28 , A61P25/08
CPC classification number: C07D403/12 , C07D239/96
Abstract: A novel quinazoline-2,4-dione derivative is provided to have the effects of antioxidation, anticonvulzure, and vasorelaxant and enhance memory and prevent and treat stroke, neurodegenerative disease, Alzheimer disease and epilepsia. A method for manufacturing quinazoline-2,4-dione compound of the chemical formula (I) comprises: a step of reacting a compound of the chemical formula (IV) with amine compound of the chemical formula (V) to obtain a compound of the chemical formula (IX); or a step of reacting a first amine compound of the chemical formula (VI) with compound of the chemical formula (VII) or (VIII) to obtain the compound of the chemical formula (IX); a step of substituting a second amine compound of the chemical formula (IX) with R2, R3 or R2 and R3 to obtain a compound of the chemical formula (Ia); and a step of removing protection group. The compound of the chemical formula (IV) is an ethyl 2-ethoxycarbonylamino benzoate.
Abstract translation: 提供了一种新颖的喹唑啉-2,4-二酮衍生物，具有抗氧化，抗痉挛和血管舒张作用，增强记忆力，预防和治疗中风，神经退行性疾病，阿尔茨海默病和癫痫。 化学式（I）的喹唑啉-2,4-二酮化合物的制造方法包括：使化学式（IV）的化合物与化学式（V）的胺化合物反应的步骤，得到化合物 化学式（IX）; 或使化学式（VI）的第一种胺化合物与化学式（VII）或（VIII）的化合物反应以获得化学式（IX）的化合物的步骤; 用R2，R3或R2和R3取代化学式（IX）的第二种胺化合物以获得化学式（Ia）的化合物的步骤; 并删除保护组的一个步骤。 化学式（IV）的化合物是2-乙氧基羰基氨基苯甲酸乙酯。
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公开(公告)号：KR1020000003837A
公开(公告)日：2000-01-25
申请号：KR1019980025129
申请日：1998-06-29
Applicant: 신풍제약주식회사
IPC: A61K31/14
CPC classification number: A61K31/661 , A61K45/06 , A61K2300/00 , Y10S514/885
Abstract: PURPOSE: An immune enhancer is provided to be used as an antibiotic and an anti-cancer medicine separately or mixed with another ingredient. CONSTITUTION: An immune enhancer containing a lombricine as an effective ingredient activates an immuno-cell of an organism for having an effect of enhancing an immune of the organism. The immune enhancer may be used as an antibiotic and an anti-cancer medicine separately or by mixed with other antibiotic or anti-cancer medicine for minimizing a virulence and maximizing an effect.
Abstract translation: 目的：提供免疫增强剂，用作抗生素和抗癌药物，或与其他成分混合使用。 构成：含有作为有效成分的洛米奇的免疫增强剂激活生物体的免疫细胞，以增强生物体的免疫作用。 免疫增强剂可以分别用作抗生素和抗癌药物，也可以与其它抗生素或抗癌药混合使用，以使毒性最小化并使效果最大化。
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Patent Agency Ranking
公开(公告)号：KR101075435B1
公开(公告)日：2011-10-24
申请号：KR1020090001655
申请日：2009-01-08
Applicant: 신풍제약주식회사
IPC: C07D239/96 , A61K31/517 , A61P25/28 , A61P25/08
CPC classification number: C07D403/12 , C07D239/96
Abstract: p는 0 또는 1의정수이다.
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公开(公告)号：KR100648739B1
公开(公告)日：2006-11-23
申请号：KR1020040032630
申请日：2004-05-10
Applicant: 신풍제약주식회사
Abstract: 본 발명은 구인(룸브리쿠스 루벨루스(
Lumbricus rubellus ))의 조추출물을 수용성 유기용매로 분별침전(fractional precipitation)하고 초여과(ultrafiltration)하는 단계를 포함하여, 항혈전 및 혈전용해 활성을 갖는 단백질분해효소(protease) 분말을 제조하는 방법에 관한 것이다.-
公开(公告)号：KR1020020046407A
公开(公告)日：2002-06-21
申请号：KR1020000076298
申请日：2000-12-14
Applicant: 신풍제약주식회사
IPC: A61K9/08
CPC classification number: A61K9/0019 , A61K31/192 , A61K47/02
Abstract: PURPOSE: Provided is a pharmaceutical composition for intramuscular injection containing loxoprofen having excellent anti-inflammatory effects, as an active ingredient, and its pharmaceutically acceptable salts. CONSTITUTION: The pharmaceutical composition for intramuscular injection contains loxoprofen represented by the formula(1) or its pharmaceutically acceptable salts. It is manufactured by dissolving loxoprofen or its pharmaceutically acceptable salt, a stabilizing agent or solution adjuvant in water for injection then sterilizing it.
Abstract translation: 目的：提供含有作为活性成分的优良抗炎作用的洛索丙芬及其药学上可接受的盐的肌内注射用药物组合物。 构成：用于肌内注射的药物组合物含有由式（1）表示的洛索洛芬或其药学上可接受的盐。 它是通过将洛索洛芬或其药学上可接受的盐，稳定剂或溶液佐剂溶解在水中，然后对其进行消毒而制造的。
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公开(公告)号：KR1020060039286A
公开(公告)日：2006-05-08
申请号：KR1020040088413
申请日：2004-11-02
Applicant: 신풍제약주식회사
IPC: A61K31/357
CPC classification number: A61K31/357 , A61K31/4375 , Y02A50/411 , A61K2300/00
Abstract: The present invention relates to an orally administrable antimalarial combined preparation containing artemisinine or its derivatives, and pyronaridine or its salts, as active ingredients, with pharmaceutically acceptable carriers, and to preparation process thereof.
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公开(公告)号：KR100405161B1
公开(公告)日：2003-11-12
申请号：KR1020000076298
申请日：2000-12-14
Applicant: 신풍제약주식회사
IPC: A61K9/08
CPC classification number: A61K9/0019 , A61K31/192 , A61K47/02
Abstract: Disclosed is a formulation for intramuscular injection containingloxoprofen or a pharmaceutically acceptable salt thereof, having an excellent anti-inflammatory analgesic effect, as an active ingredient.
Abstract translation: 本发明公开了含有洛索洛芬或其药学上可接受的盐作为有效成分，具有优异的消炎镇痛作用的肌内注射用制剂。
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