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Patent Agency Ranking
公开(公告)号：KR100883548B1
公开(公告)日：2009-02-13
申请号：KR1020080101219
申请日：2008-10-15
Applicant: 충남대학교산학협력단
IPC: C07D307/14 , C07D307/16
Abstract: 본 발명은 하기 화학식 2로 표시되는 우레아계 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 돼지의 발정 유도용 조성물에 관한 것이다.
[화학식 2]
상기 화학식 2에서 m, n은 각각 0~5이고, Z는 O 또는 S이다. R
4 는 2-테트라하이드로퓨릴, 2-퓨라닐, 페닐, 메톡시페닐, 톨루일, 3,5-디메틸페닐, 3-플로로-6-메틸페닐 또는 피리딜이며, R
6 는 메톡시페닐, 디메톡시페닐, 디메틸페닐, 에틸페닐, 3-클로로-6-메톡시페닐, 4-클로로-2-메틸페닐, 3-클로로-6-메틸페닐, 플로로페닐, 클로로페닐, 2,5-디플로로페닐 또는 피리딜이고, R
5 와 R
7 은 각각 H 또는 메틸기이다.
본 발명의 페로몬성 냄새물질은 합성이 용이하므로 이를 유효성분으로 함유하는 발정 유도용 조성물은 수급이 안정적이고 경제적으로 돼지의 발정을 동기화하여 번식효율을 향상시킬 뿐만 아니라, 노동력을 감소시킴으로써 양돈 경영의 효율성을 높일 수 있다.
우레아계 화합물, 돼지, 번식조절, 페로몬성 물질, 발정 동기화.-
公开(公告)号：KR100881137B1
公开(公告)日：2009-02-02
申请号：KR1020070078882
申请日：2007-08-07
Applicant: 충남대학교산학협력단
IPC: C07D307/14 , C07D307/16
Abstract: A composite for estrus induction of pig and a manufacturing method of an amide compound are provided to are provided pheromone type odor material easily, to be supplied stably and to synchronize the estrus of the pig economically. A composite for estrus induction of pig comprises an amide compound indicated by a chemical formula 1 as an active ingredient. In the chemical formula 1, m is 1, X is CO, Y is CO or CH2, R1 and R2 are H, R3 is allyl or pyridine carbonyl. A manufacturing method of the amide compound comprises steps of: manufacturing lower alkyl oxalyl amide(B) of C1~C4 by reaction of lower alkyl oxalyl chloride of C1~C4 and amine; and manufacturing oxalyl amide(I) by reaction of tetrahydrofuryl amine and the lower alkyl oxalyl amide(B).
Abstract translation: 提供猪的发情综合征和酰胺化合物的制造方法，易于提供信息素型气味物质，供应稳定，经济地使猪的发情同步。 用于猪发情诱导的复合物包含由化学式1表示的酰胺化合物作为活性成分。 在化学式1中，m为1，X为CO，Y为CO或CH2，R1和R2为H，R3为烯丙基或吡啶羰基。 酰胺化合物的制造方法包括以下步骤：通过C1-C4的低级烷基草酰氯和胺的反应制备C1-C4的低级烷基草酰胺（B）; 并通过四氢呋喃胺和低级烷基草酰胺（B）的反应制备草酰胺（I）。
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公开(公告)号：KR1020090015007A
公开(公告)日：2009-02-11
申请号：KR1020080101219
申请日：2008-10-15
Applicant: 충남대학교산학협력단
IPC: C07D307/14 , C07D307/16
Abstract: A pig pheromonal urea-based compounds are provided to enhance the estrus induction efficiency of pig, facilitate the synthesis of compounds, stabilize the supply of the compounds, and reduce the compound production costs. The pig pheromonal urea-based compounds represented by the chemical formula(2) are useful for induction of estrus, wherein m and n are each independently 0 to 5; Z is O or S; R4 is 2-tetrahydrofuryl, 2-furanyl, phenyl, methoxy phenyl, toluyl, 3,5-dimethyl phenyl, 3-fluoro-6-methyl phenyl or pyridyl; R6 is methoxy phenyl, dimethoxyphenyl, dimethyl phenyl, ethylphenyl, 3-chloro-6-methoxy phenyl, 4-chloro-2-methyl phenyl, 3-chloro-6-methyl phenyl, fluorophenyl, chlorophenyl, 2,5-difluorophenyl or pyridyl; and R5 and R7 are each independently H or methyl group.
Abstract translation: 提供猪信息素尿素化合物以增强猪的发情诱导效率，促进化合物的合成，稳定化合物的供应，降低化合物的生产成本。 由化学式（2）表示的猪信息素脲基化合物可用于诱发发情，其中m和n各自独立地为0至5; Z是O或S; R4是2-四氢呋喃基，2-呋喃基，苯基，甲氧基苯基，甲苯酰基，3,5-二甲基苯基，3-氟-6-甲基苯基或吡啶基; R6是甲氧基苯基，二甲氧基苯基，二甲基苯基，乙基苯基，3-氯-6-甲氧基苯基，4-氯-2-甲基苯基，3-氯-6-甲基苯基，氟苯基，氯苯基，2,5-二氟苯基或吡啶基 ; 并且R 5和R 7各自独立地为H或甲基。
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公开(公告)号：KR100863572B1
公开(公告)日：2008-10-15
申请号：KR1020070060419
申请日：2007-06-20
Applicant: 충남대학교산학협력단
IPC: C07D307/12 , A61K31/341
Abstract: A novel pheromonal odorant is provided to be easily synthesized, thereby a composition comprising the same compound improving breeding efficiency through estrus synchronization of pig stably and economically and increasing the efficiency of pig farming management by decreasing labor force. A tetrahydrofuran based compound is represented by a formula(1). A composition for inducing estrus of pig or cow comprises the tetrahydrofuran based compound as an effective ingredient.
Abstract translation: 提供了一种易于合成的新型信息增感剂，由此提供了一种包含相同化合物的组合物，通过猪的发情同步稳定和经济地提高育种效率，并通过减少劳动力提高养猪管理的效率。 四氢呋喃类化合物由式（1）表示。 用于诱导猪或牛发情的组合物包括四氢呋喃类化合物作为有效成分。
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