Abstract:
PURPOSE: A hybrid bioreactor for the cell culture is provided, thereby simultaneously applying a shear strain for stimulating the cell proliferation and a compressive strain for stimulating the cell differentiation to cells, so that the cell proliferation and the cell differentiation can be simultaneously stimulated in the bioreactor. CONSTITUTION: A hybrid bioreactor for the cell culture comprises numerous culture vessel assemblies(100); a compressive strain motor(5); a ball screw(90) connected to the compressive strain motor(5) to be moved together; a pressurizing plate(60) connected to the ball screw(90) to move vertically, and having numerous compressive strain supports(80) fixing the lower portion of each culture vessel assembly(100); a lower supporting plate(20) fixing the lower portion of each culture vessel assembly(100) and having numerous lower supporting blocks(70) with a gear tooth on the circumference surface; a shear strain motor(25); and a power transferring unit for transferring the rotation power of the shear strain motor(25) to the numerous lower supporting blocks(70).
Abstract:
The impurity expansion method is used for bonding Mtransistor source, less than 1 micron width, and doping bipolar transistor emitter or base. The impurity expansion apparatus comprises a surrounding gas inlet (22) formed at one side of a quartz tube (12); a quartz tray (14) insertable into the quartz tube (12); a tungsten-halogen lamp (13) heating the inner part of the quartz tube (12); a reflection plate (11) for enhancing the heat efficiency of the tungsten-halgen lamp (13); non-reflective membrane (24) covered on a reflection plate face; a pyrometer window (25) formed on the reflection plate (11); a pyrometer (27) supported by a support (26) equipped in the upper part of the window (25).
Abstract:
A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).