-
公开(公告)号：KR1020120130477A
公开(公告)日：2012-12-03
申请号：KR1020110048433
申请日：2011-05-23
Applicant: 한국인스팜(주) , 전남대학교산학협력단
IPC: A61K36/185 , A61P3/04 , A61P3/00
Abstract: PURPOSE: A composition containing Lardizabalaceae extract is provided to suppress adipocyte differentiation and to prevent and treat obesity. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity contains Lardizabalaceae extract as an active ingredient. The Lardizabalaceae extract is prepared from Lardizabalaceae leaves, stems, or whole plant using water, low carbon number alcohol of 1-4 carbon atoms, or a mixture thereof. A health functional food for preventing and treating obesity contains the Lardizabalaceae extract as an active ingredient. The health functional food is powder, granules, tablets, capsules, or drinks. A food additive for preventing and treating obesity contains the Lardizabalaceae extract as a main ingredient.
Abstract translation: 目的：提供含有Lardizabalaceae提取物的组合物以抑制脂肪细胞分化和预防和治疗肥胖。 构成：用于预防和治疗肥胖症的药物组合物含有Lardizabalaceae提取物作为活性成分。 Lardizabalaceae提取物使用水，1-4碳原子的低碳数醇或其混合物从Lardizabalaceae叶，茎或全植物制备。 用于预防和治疗肥胖症的健康功能食品含有Lardizabalaceae提取物作为活性成分。 健康功能食品是粉末，颗粒，片剂，胶囊或饮料。 用于预防和治疗肥胖症的食品添加剂含有Lardizabalaceae提取物作为主要成分。
-
2.发明授权
公开(公告)号：KR101407150B1
公开(公告)日：2014-07-14
申请号：KR1020120112449
申请日：2012-10-10
Applicant: 한국인스팜(주) , 전남대학교산학협력단
IPC: A61K36/73 , A61K36/738 , A61P25/00
Abstract: 본 발명은 해당화 줄기 및 잎 추출물을 함유하는 조성물에 관한 것으로, 해당화 줄기 및 잎을 다양한 용매를 이용하여 추출, 농축하여 수득 가능한 분말 또는 엑기스를 포함하는 수면부족상태로 기인한 스트레스관련 질환에 대한 억제, 예방 및 개선을 위한 약학조성물 및 건강기능식품에 관한 것으로, 본 발명에 의한 해당화 줄기 및 잎 추출물은 랫트에서 수면박탈에 대항하여 생존율 증가, 꾸벅임 감소, 코티졸 함량 감소효과 및 신경세포 보호효과가 탁월함을 확인하였다.
-
公开(公告)号：KR1020140026737A
公开(公告)日：2014-03-06
申请号：KR1020120092198
申请日：2012-08-23
Applicant: 한국인스팜(주) , 재단법인 전남생물산업진흥원 , 전남대학교산학협력단
IPC: A61K36/9066 , A61P1/16 , A61P25/32
Abstract: The present invention relates to a composition containing fermented Curcuma longa powder for treating alcoholic liver damage. The fermented Curcuma longa powder of the present invention is obtained by fermenting materials for the fermented Curcuma longa powder using Aspergillus oryzae, and sterilizing and drying the materials, and shows a strong liver damage control function in an alcoholic liver damage model. The composition can be practically used for treatment and prevention food for alcoholic liver damage, medical products, and outer medical products using the fermented Curcuma longa powder.
Abstract translation: 本发明涉及含有用于治疗酒精性肝损伤的发酵姜黄粉的组合物。 本发明的发酵姜黄粉是通过使用米曲霉发酵的姜黄发酵材料进行发酵而得到的，对该材料进行灭菌干燥，在酒精性肝损伤模型中显示出强烈的肝损伤控制功能。 该组合物可用于治疗和预防酒精性肝损伤的食物，医疗产品和使用发酵的姜黄粉的外用医药产品。
-
4.发明公开
公开(公告)号：KR1020140046233A
公开(公告)日：2014-04-18
申请号：KR1020120112449
申请日：2012-10-10
Applicant: 한국인스팜(주) , 전남대학교산학협력단
IPC: A61K36/73 , A61K36/738 , A61P25/00
CPC classification number: A61K36/738 , A23V2200/322 , A61K2236/331
Abstract: The present invention relates to a composition comprising an extract of Rosa rugosa stem and leaves and, more specifically, to a pharmaceutical composition and a functional health food for suppressing, preventing, and alleviating stress-related diseases caused by a lack of sleep which comprises a powder or an extract obtainable by extracting and concentrating Rosa rugosa stem and leaves by using various solvents. The extract of Rosa rugosa stem and leaves according to the present invention is confirmed to have excellent effects for increasing survival rate, reducing drowsing, reducing cortisol content, and protecting nerve cells against sleep deprivation in rats.
Abstract translation: 本发明涉及一种组合物，其包含罗莎蔷薇茎和叶的提取物，更具体地涉及用于抑制，预防和减轻由睡眠不足引起的与压力有关的疾病的药物组合物和功能保健食品，其包含 粉末或通过使用各种溶剂提取和浓缩罗莎蔷薇茎叶而获得的提取物。 确认本发明的罗莎芦苇提取物对提高存活率，降低呕吐，降低皮质醇含量，保护神经细胞免受大鼠睡眠剥夺的作用具有优异的效果。
-
-
Patent Agency Ranking6.发明公开
公开(公告)号：KR1020140020433A
公开(公告)日：2014-02-19
申请号：KR1020120086755
申请日：2012-08-08
Applicant: 한국인스팜(주)
IPC: A61K36/752 , A61P13/08 , A61P13/00
CPC classification number: A61K36/752 , A61K2236/331 , A61K2236/333
Abstract: The present invention relates to a composition containing an extract of Citrus junos for preventing and treating benign prostatic hyperplasia. The extract of Citrus junos shows high survival rate of cells with high cytotoxicity among prostatic carcinoma cells, inhibitory activity for 5-alpha- reductase type 1 and 2 extracted from liver of SD rat grown for 12 weeks in which prostatomegaly is induced, a control effect of 5RD activity in 5RD type 2 overexpressed prostate cells, and a control effect of mRNA of PSA. The extract of Citrus junos also shows the significant reduction of DHT change in a prostatomegaly induction experiment using rats to be usefully applied to a pharmaceutical composition for preventing and treating benign prostatic hyperplasia and health functional food. [Reference numerals] (AA,DD) Citrus junos(water); (BB,EE) Citrus junos(20% alcohol); (CC,FF) Citrus junos(80% alcohol)
Abstract translation: 本发明涉及含有用于预防和治疗良性前列腺增生的柑橘属杜鹃花提取物的组合物。 柠檬提取物表现出前列腺癌细胞细胞毒性高的细胞存活率高，生长前列腺增生12周的SD大鼠肝脏提取的5型α-还原酶1型和2型的抑制活性为对照组， 的5RD 2型过表达前列腺细胞中的5RD活性，以及PSA的mRNA的控制作用。 Citrus junos的提取物还显示使用大鼠有用地应用于预防和治疗良性前列腺增生和健康功能性食物的药物组合物的前列腺肥大诱导实验中DHT变化的显着降低。 （参考号）（AA，DD）柑橘属（水）; （BB，EE）Citrus junos（20％酒精）; （CC，FF）柑橘类（80％酒精）
-
7.发明公开해당화 추출물을 유효성분으로 함유하는 수면부족으로 인한 스트레스 관련 질환의 치료 및 예방을 위한 조성물 无效包含ROSA RUGOSA的提取物的组合物和功能食品，预防或治疗由休眠导致的紧张性疾病引起的疾病
公开(公告)号：KR1020130090936A
公开(公告)日：2013-08-16
申请号：KR1020120012067
申请日：2012-02-07
Applicant: 한국인스팜(주)
IPC: A61K36/738 , A61K36/73 , A61P25/00
Abstract: PURPOSE: A composition for preventing and treating diseases caused by lack of sleep is provided to prevent nerve cell damage due to a stress inducer in nerve cells (SH-SY5), to suppress stress, and to obtain a pharmaceutical composition or a health food for suppressing, treating, preventing, and alleviating diseases caused by stress. CONSTITUTION: A pharmaceutical composition for preventing and treating stress-related diseases contains a Rosa rugosa extract as an active ingredient. The extract is prepared from Rosa rugosa stems, flowers, roots, or plants using water, spirit, C1-C4 alcohols, or a mixture thereof. The stress-related diseases are depression, insomnia, hypersomnia, hypnolepsy, circadian rhythm sleep disorder, incubus, or somnambulism. [Reference numerals] (AA) Rosa rugosa
Abstract translation: 目的：提供一种用于预防和治疗由睡眠不足引起的疾病的组合物，以防止由于神经细胞（SH-SY5）中的应激诱导剂引起的神经细胞损伤，抑制应激，并获得药物组合物或保健食品 抑制，治疗，预防和缓解压力引起的疾病。 构成：用于预防和治疗应激相关疾病的药物组合物含有罗莎玫瑰提取物作为活性成分。 使用水，精油，C1-C4醇或其混合物从罗莎蔷薇茎，花，根或植物制备提取物。 压力相关的疾病是抑郁症，失眠症，睡眠过多，hypnoleys，昼夜节律睡眠障碍，孵化或嗜睡症。 （附图标记）（AA）罗莎
-
公开(公告)号：KR101077522B1
公开(公告)日：2011-10-27
申请号：KR1020090062900
申请日：2009-07-10
Applicant: 한국인스팜(주)
Abstract: 본발명은퇴행성뇌질환의예방및 치료용조성물에관한것으로, 상세하게는비파엽의추출물을유효성분으로함유하는본 발명의조성물은라디칼소거능및 뇌세포에대한뛰어난보호효과를나타내므로, 퇴행성뇌질환의예방및 치료를위한약학조성물및 건강기능식품으로유용하게이용될수 있다.
-
9.发明公开울금 비극성용매 가용 추출물 또는 이로부터 분리된 아로매틱-튜메론을 유효성분으로 함유하는 스트레스관련 질환의 치료 및 예방을 위한 조성물 有权一种组合物，其包含用于预防或治疗与应激相关的疾病的非极性溶剂可溶性提取物或ar-turmerone
公开(公告)号：KR1020150036936A
公开(公告)日：2015-04-08
申请号：KR1020130115995
申请日：2013-09-30
Applicant: 한국인스팜(주) , 재단법인 전남생물산업진흥원
IPC: A61K36/9066 , A61P25/00
CPC classification number: A61K36/9066 , A23L33/105 , A23V2002/00 , A23V2200/322 , A23V2250/2112
Abstract: 본발명은울금비극성용매가용추출물또는이로부터분리된아로매틱-튜메론 (ar-turmerone)을함유하는조성물에관한것으로, 본발명의울금비극성용매가용추출물또는이로부터분리된아로매틱-튜메론 (ar-turmerone)들을대상으로한 SD 랫트의대뇌피질을이용한세포독성실험및 대뇌피질세포에서정신적스트레스로인해분비되는스트레스호르몬인코르티코스테론에의한신경세포손상에대한신경세포손상보호효과를확인한실험결과, 강력한신경세포손상보호효과활성을나타냄을확인함으로써, 상기조성물을스트레스관련질환의예방및 치료용약학조성물또는건강기능식품으로유용함을확인하였다.
Abstract translation: 本发明涉及含有分离自其的姜黄的非极性溶剂可溶性提取物或芳香族姜黄素的组合物。 根据本发明，使用SD大鼠的大脑皮层进行的细胞毒性实验和神经元损伤预防效果的验证实验已经对从其分离的姜黄的非极性溶剂可溶性提取物或芳香族姜黄素进行了，其中 神经元损伤预防效应是指由皮质酮引起的神经元损伤，皮质酮是由于大脑皮质细胞的心理压力而分泌的应激激素。 作为实验结果，已经证实了从其分离的姜黄的非极性溶剂可溶性提取物或芳香族姜黄素具有强烈的神经元损伤预防效果。 因此，已经证实该组合物可用于药物组合物或用于预防和治疗应激相关疾病的保健食品。
-
公开(公告)号：KR101373653B1
公开(公告)日：2014-03-14
申请号：KR1020120012066
申请日：2012-02-07
Applicant: 한국인스팜(주)
IPC: A61K36/73 , A61K36/738 , A61P13/08
Abstract: 본 발명은 해당화 추출물을 포함하는 전립선 비대증 예방 및 치료를 위한 조성물에 관한 것으로서, 본 발명의 해당화 추출물은 인체 전립선암 세포주 세포독성이 높은 세포 생존률, 전립선비대가 유발된 12주령의 SD 래트 간으로부터 추출된 5-알파(alpha)-리덕타제(reductase) 1형 및 2형에 대한 저해능, 5RD 2형 과발현 전립선 세포주에서의 5RD 활성 억제효과 및 PSA의 mRNA 발현 억제효과, 및 COX-2, iNOS, IL-6, IL-1beta 등의 염증시그널의 감소효과를 나타내므로 전립선 비대증 예방 및 치료를 위한 약학조성물 및 건강기능식품에 유용하게 이용될 수 있다.
-
-
-
-
-
-
-
-
-
Search Results
42
records
(took 0.024 seconds)
