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公开(公告)号：KR1020120130477A
公开(公告)日：2012-12-03
申请号：KR1020110048433
申请日：2011-05-23
Applicant: 한국인스팜(주) , 전남대학교산학협력단
IPC: A61K36/185 , A61P3/04 , A61P3/00
Abstract: PURPOSE: A composition containing Lardizabalaceae extract is provided to suppress adipocyte differentiation and to prevent and treat obesity. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity contains Lardizabalaceae extract as an active ingredient. The Lardizabalaceae extract is prepared from Lardizabalaceae leaves, stems, or whole plant using water, low carbon number alcohol of 1-4 carbon atoms, or a mixture thereof. A health functional food for preventing and treating obesity contains the Lardizabalaceae extract as an active ingredient. The health functional food is powder, granules, tablets, capsules, or drinks. A food additive for preventing and treating obesity contains the Lardizabalaceae extract as a main ingredient.
Abstract translation: 目的：提供含有Lardizabalaceae提取物的组合物以抑制脂肪细胞分化和预防和治疗肥胖。 构成：用于预防和治疗肥胖症的药物组合物含有Lardizabalaceae提取物作为活性成分。 Lardizabalaceae提取物使用水，1-4碳原子的低碳数醇或其混合物从Lardizabalaceae叶，茎或全植物制备。 用于预防和治疗肥胖症的健康功能食品含有Lardizabalaceae提取物作为活性成分。 健康功能食品是粉末，颗粒，片剂，胶囊或饮料。 用于预防和治疗肥胖症的食品添加剂含有Lardizabalaceae提取物作为主要成分。
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2.发明授权
公开(公告)号：KR101407150B1
公开(公告)日：2014-07-14
申请号：KR1020120112449
申请日：2012-10-10
Applicant: 한국인스팜(주) , 전남대학교산학협력단
IPC: A61K36/73 , A61K36/738 , A61P25/00
Abstract: 본 발명은 해당화 줄기 및 잎 추출물을 함유하는 조성물에 관한 것으로, 해당화 줄기 및 잎을 다양한 용매를 이용하여 추출, 농축하여 수득 가능한 분말 또는 엑기스를 포함하는 수면부족상태로 기인한 스트레스관련 질환에 대한 억제, 예방 및 개선을 위한 약학조성물 및 건강기능식품에 관한 것으로, 본 발명에 의한 해당화 줄기 및 잎 추출물은 랫트에서 수면박탈에 대항하여 생존율 증가, 꾸벅임 감소, 코티졸 함량 감소효과 및 신경세포 보호효과가 탁월함을 확인하였다.
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公开(公告)号：KR1020140026737A
公开(公告)日：2014-03-06
申请号：KR1020120092198
申请日：2012-08-23
Applicant: 한국인스팜(주) , 재단법인 전남생물산업진흥원 , 전남대학교산학협력단
IPC: A61K36/9066 , A61P1/16 , A61P25/32
Abstract: The present invention relates to a composition containing fermented Curcuma longa powder for treating alcoholic liver damage. The fermented Curcuma longa powder of the present invention is obtained by fermenting materials for the fermented Curcuma longa powder using Aspergillus oryzae, and sterilizing and drying the materials, and shows a strong liver damage control function in an alcoholic liver damage model. The composition can be practically used for treatment and prevention food for alcoholic liver damage, medical products, and outer medical products using the fermented Curcuma longa powder.
Abstract translation: 本发明涉及含有用于治疗酒精性肝损伤的发酵姜黄粉的组合物。 本发明的发酵姜黄粉是通过使用米曲霉发酵的姜黄发酵材料进行发酵而得到的，对该材料进行灭菌干燥，在酒精性肝损伤模型中显示出强烈的肝损伤控制功能。 该组合物可用于治疗和预防酒精性肝损伤的食物，医疗产品和使用发酵的姜黄粉的外用医药产品。
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4.发明公开
公开(公告)号：KR1020140046233A
公开(公告)日：2014-04-18
申请号：KR1020120112449
申请日：2012-10-10
Applicant: 한국인스팜(주) , 전남대학교산학협력단
IPC: A61K36/73 , A61K36/738 , A61P25/00
CPC classification number: A61K36/738 , A23V2200/322 , A61K2236/331
Abstract: The present invention relates to a composition comprising an extract of Rosa rugosa stem and leaves and, more specifically, to a pharmaceutical composition and a functional health food for suppressing, preventing, and alleviating stress-related diseases caused by a lack of sleep which comprises a powder or an extract obtainable by extracting and concentrating Rosa rugosa stem and leaves by using various solvents. The extract of Rosa rugosa stem and leaves according to the present invention is confirmed to have excellent effects for increasing survival rate, reducing drowsing, reducing cortisol content, and protecting nerve cells against sleep deprivation in rats.
Abstract translation: 本发明涉及一种组合物，其包含罗莎蔷薇茎和叶的提取物，更具体地涉及用于抑制，预防和减轻由睡眠不足引起的与压力有关的疾病的药物组合物和功能保健食品，其包含 粉末或通过使用各种溶剂提取和浓缩罗莎蔷薇茎叶而获得的提取物。 确认本发明的罗莎芦苇提取物对提高存活率，降低呕吐，降低皮质醇含量，保护神经细胞免受大鼠睡眠剥夺的作用具有优异的效果。
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Patent Agency Ranking6.发明授权
公开(公告)号：KR101099786B1
公开(公告)日：2011-12-28
申请号：KR1020090058304
申请日：2009-06-29
Applicant: 한국인스팜(주)
Abstract: 본 발명은 뇌세포 보호 활성을 갖는 조성물에 관한 것으로, 상세하게는 원지 조 추출물의 산가수분해성 분획물을 유효성분으로 함유하는 본 발명의 조성물은 뇌세포에 대한 뛰어난 보호 및 항산화 효과를 나타내므로, 퇴행성 뇌질환의 예방 및 치료를 위한 약학조성물 및 건강기능식품으로 유용하게 이용될 수 있다.
원지, 뇌 세포 보호, 산가수분해물, 항산화효과-
公开(公告)号：KR101383146B1
公开(公告)日：2014-04-09
申请号：KR1020120052744
申请日：2012-05-18
Applicant: 한국인스팜(주)
Abstract: 본 발명은 갈화(칡꽃), 상심(오디), 오미자, 상엽(뽕잎), 지구자(헛개나무열매), 국호(국화), 진피(귤껍질), 맥문동 및 당삼(만삼)으로 구성된 복합생약 추출물을 유효성분으로 함유하는 간 질환 및 숙취의 예방 및 치료를 위한 조성물에 관한 것으로, 본 발명의 추출물은
in
vitro 상에서 ADH 및 ALDH 효소 수준을 억제하고
in
vivo 상에서는 Ethanol과 Acetaldehyde의 혈중 농도를 유의적으로 억제하는 숙취해소 및 간질환에 대한 치료 효과를 확인함으로써, 숙취해소 및 간질환의 예방 및 치료용 약학조성물에 이용될 수 있다.-
8.发明公开
公开(公告)号：KR1020140020433A
公开(公告)日：2014-02-19
申请号：KR1020120086755
申请日：2012-08-08
Applicant: 한국인스팜(주)
IPC: A61K36/752 , A61P13/08 , A61P13/00
CPC classification number: A61K36/752 , A61K2236/331 , A61K2236/333
Abstract: The present invention relates to a composition containing an extract of Citrus junos for preventing and treating benign prostatic hyperplasia. The extract of Citrus junos shows high survival rate of cells with high cytotoxicity among prostatic carcinoma cells, inhibitory activity for 5-alpha- reductase type 1 and 2 extracted from liver of SD rat grown for 12 weeks in which prostatomegaly is induced, a control effect of 5RD activity in 5RD type 2 overexpressed prostate cells, and a control effect of mRNA of PSA. The extract of Citrus junos also shows the significant reduction of DHT change in a prostatomegaly induction experiment using rats to be usefully applied to a pharmaceutical composition for preventing and treating benign prostatic hyperplasia and health functional food. [Reference numerals] (AA,DD) Citrus junos(water); (BB,EE) Citrus junos(20% alcohol); (CC,FF) Citrus junos(80% alcohol)
Abstract translation: 本发明涉及含有用于预防和治疗良性前列腺增生的柑橘属杜鹃花提取物的组合物。 柠檬提取物表现出前列腺癌细胞细胞毒性高的细胞存活率高，生长前列腺增生12周的SD大鼠肝脏提取的5型α-还原酶1型和2型的抑制活性为对照组， 的5RD 2型过表达前列腺细胞中的5RD活性，以及PSA的mRNA的控制作用。 Citrus junos的提取物还显示使用大鼠有用地应用于预防和治疗良性前列腺增生和健康功能性食物的药物组合物的前列腺肥大诱导实验中DHT变化的显着降低。 （参考号）（AA，DD）柑橘属（水）; （BB，EE）Citrus junos（20％酒精）; （CC，FF）柑橘类（80％酒精）
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9.发明公开해당화 추출물을 유효성분으로 함유하는 수면부족으로 인한 스트레스 관련 질환의 치료 및 예방을 위한 조성물 无效包含ROSA RUGOSA的提取物的组合物和功能食品，预防或治疗由休眠导致的紧张性疾病引起的疾病
公开(公告)号：KR1020130090936A
公开(公告)日：2013-08-16
申请号：KR1020120012067
申请日：2012-02-07
Applicant: 한국인스팜(주)
IPC: A61K36/738 , A61K36/73 , A61P25/00
Abstract: PURPOSE: A composition for preventing and treating diseases caused by lack of sleep is provided to prevent nerve cell damage due to a stress inducer in nerve cells (SH-SY5), to suppress stress, and to obtain a pharmaceutical composition or a health food for suppressing, treating, preventing, and alleviating diseases caused by stress. CONSTITUTION: A pharmaceutical composition for preventing and treating stress-related diseases contains a Rosa rugosa extract as an active ingredient. The extract is prepared from Rosa rugosa stems, flowers, roots, or plants using water, spirit, C1-C4 alcohols, or a mixture thereof. The stress-related diseases are depression, insomnia, hypersomnia, hypnolepsy, circadian rhythm sleep disorder, incubus, or somnambulism. [Reference numerals] (AA) Rosa rugosa
Abstract translation: 目的：提供一种用于预防和治疗由睡眠不足引起的疾病的组合物，以防止由于神经细胞（SH-SY5）中的应激诱导剂引起的神经细胞损伤，抑制应激，并获得药物组合物或保健食品 抑制，治疗，预防和缓解压力引起的疾病。 构成：用于预防和治疗应激相关疾病的药物组合物含有罗莎玫瑰提取物作为活性成分。 使用水，精油，C1-C4醇或其混合物从罗莎蔷薇茎，花，根或植物制备提取物。 压力相关的疾病是抑郁症，失眠症，睡眠过多，hypnoleys，昼夜节律睡眠障碍，孵化或嗜睡症。 （附图标记）（AA）罗莎
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公开(公告)号：KR101077522B1
公开(公告)日：2011-10-27
申请号：KR1020090062900
申请日：2009-07-10
Applicant: 한국인스팜(주)
Abstract: 본발명은퇴행성뇌질환의예방및 치료용조성물에관한것으로, 상세하게는비파엽의추출물을유효성분으로함유하는본 발명의조성물은라디칼소거능및 뇌세포에대한뛰어난보호효과를나타내므로, 퇴행성뇌질환의예방및 치료를위한약학조성물및 건강기능식품으로유용하게이용될수 있다.
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