公开(公告)号：KR100848116B1

公开(公告)日：2008-07-24

申请号：KR1020070022400

申请日：2007-03-07

Applicant: 한국화학연구원

Inventor： 박창식 ,  최은복 ,  이현규 ,  최경자 ,  양희철 ,  황보현

IPC: C07D487/04 ,  A01N43/36

Abstract: Methoxyacrylate or methoxyiminoacetate derivatives with substituted triazoloimidazole are provided to show the wide range of sterilization effects on plant pathogenic bacteria including resistant bacteria, and improve plant penetration, and disease prevention and treatment effects. The methoxyacrylate or methoxyiminoacetate derivatives with substituted triazoloimidazole represented by the formula(1) are prepared by reacting compounds represented by the formula(2) with compounds represented by the formula(3) in the presence of mixed solvent of water and inert organic solvent by using acid scavenger and phase transfer catalyst, wherein R1 is C1-C3 alkyl group or benzyl group optionally substituted by halogen group or C1-C3 alkoxy group; R2 is hydrogen, C1-C3 alkyl group or halogen group; X is hydrogen, C1-C2 alkyl group or C1-C2 alkoxy group; Y is N or CH; and P is Br or Cl. Further, the acid scavenger is one of triethylamine, sodium hydrogen carbonate, potassium carbonate or sodium hydroxide.

Abstract translation: 提供了具有取代的三唑并咪唑的甲氧基丙烯酸酯或甲氧基亚氨基乙酸酯衍生物，以显示对包括耐药性细菌在内的植物致病菌的杀菌效果的广泛范围，并提高植物的渗透性和疾病预防和治疗效果。 由式（1）表示的具有取代的三唑并咪唑的甲氧基丙烯酸酯或甲氧基亚氨基乙酸酯衍生物通过使用式（2）表示的化合物与式（3）表示的化合物在水和惰性有机溶剂的混合溶剂的存在下，通过使用 酸清除剂和相转移催化剂，其中R 1是任选被卤素基或C 1 -C 3烷氧基取代的C 1 -C 3烷基或苄基; R2是氢，C1-C3烷基或卤素基团; X是氢，C 1 -C 2烷基或C 1 -C 2烷氧基; Y为N或CH; 并且P是Br或Cl。 此外，酸清除剂是三乙胺，碳酸氢钠，碳酸钾或氢氧化钠中的一种。