公开(公告)号：EP0588972A4

公开(公告)日：1994-09-14

申请号：EP92914654

申请日：1992-06-11

Applicant: ABBOTT LAB

Inventor： CORBETT KEVIN M ,  LADD JIMMY L

IPC: G01N21/17 ,  B01L3/00 ,  B01L3/02 ,  G01N15/14 ,  G01N21/82 ,  G01N33/48 ,  G01N33/483 ,  G01N33/543 ,  G01N33/80 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  G02B7/28 ,  G06T1/00 ,  G06K9/00

CPC classification number: G01N35/109 ,  B01L3/0262 ,  B01L3/5085 ,  G01N15/1468 ,  G01N21/82 ,  G01N35/0095 ,  G01N35/0098 ,  G01N35/028 ,  G01N35/1004 ,  G01N2035/042 ,  G01N2035/0425 ,  G01N2035/0491 ,  G01N2035/1018 ,  G01N2035/1025 ,  G01N2035/1034 ,  G01N2201/0446 ,  G01N2201/0461 ,  G01N2201/0492 ,  G02B7/28 ,  Y10T137/7306 ,  Y10T436/115831

Abstract: A method is provided for auto-positioning auto-focusing reaction wells for optically imaging purposes within a programmable random access automated apparatus for performing assays wherein the apparatus includes a reaction cartridge (10) having a plurality of reaction wells requiring precision location of the reaction wells (16) within an image allowing accurate transfer of the optical images to a logic system for analyzing the optical information. The optical imaging system (185) provides a generated visual indication of the results of the assays being performed. A micro processor is provided to assist in the operation of the apparatus as well as the imaging processing.

Abstract translation: 提供了一种装置，其包括具有多个反应孔的反应筒，反应孔具有设置在其上的不同试剂，至少一个适于接收样品的孔，含有适于结合样品的颗粒的孔，并具有与样品分离的能力 不结合分离颗粒的细胞和适于结合样品中特定类型的细胞的至少一种荧光团和适于洗涤探针的洗涤区域。 提供图像形成装置以检测指示每个反应孔中是否发生特定反应的图像。 该装置还包括用于分配和抽吸液体的机构，包括用于检测液位的机构。 该装置还包括用于分析从图像检测装置接收的信息并处理信息以生成正在执行的测定结果的视觉指示的逻辑。 提供微处理器以帮助设备的操作以及图像处理。

公开(公告)号：EP0588931A4

公开(公告)日：1994-06-22

申请号：EP92913497

申请日：1992-06-11

Applicant: ABBOTT LAB

Inventor： CHOW HERBERT S ,  WILSON THOMAS J ,  WROBLEWSKI MIECZYSLAW ,  KOTLARIK JOHN J ,  ALSBERG KEITH D ,  MCCOY JIMMY D ,  LADD JIMMY L ,  CORBETT KEVIN M

IPC: G01N21/17 ,  B01L3/00 ,  B01L3/02 ,  G01N15/14 ,  G01N21/82 ,  G01N33/48 ,  G01N33/483 ,  G01N33/543 ,  G01N33/80 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  G02B7/28 ,  G06T1/00 ,  G01N21/01

CPC classification number: G01N35/109 ,  B01L3/0262 ,  B01L3/5085 ,  G01N15/1468 ,  G01N21/82 ,  G01N35/0095 ,  G01N35/0098 ,  G01N35/028 ,  G01N35/1004 ,  G01N2035/042 ,  G01N2035/0425 ,  G01N2035/0491 ,  G01N2035/1018 ,  G01N2035/1025 ,  G01N2035/1034 ,  G01N2201/0446 ,  G01N2201/0461 ,  G01N2201/0492 ,  G02B7/28 ,  Y10T137/7306 ,  Y10T436/115831

Abstract: An apparatus is provided for moving a reaction cartridge (10) to different processing areas (36, 38, 42) of the apparatus. Robots (34, 40) for moving the reaction cartridge to the various areas (30, 32, 36, 38, 42, 46) of the apparatus. An image forming device (42) is provided to detect images which indicate whether specific reactions have occurred in reaction wells (16) of the reaction cartridge (10). The apparatus also includes a mechanism (36) for aspirating and dispensing liquids which includes a liquid level detecting mechanism (70, 72, 74, 76, 78, 80, 82, 84). The device further includes a microprocessor and logic (44) for controlling the apparatus operation and analyzing the information received from the image forming device (42) to generate a visual indication of assay results.