公开(公告)号：SE7812825A

公开(公告)日：1979-06-22

申请号：SE7812825

申请日：1978-12-13

Applicant: ABBOTT LAB

Inventor： DUNNIGAN D A ,  MARTIN J R ,  TADANIER J S ,  FREIBERG L A

IPC: C07H15/224 ,  C07H15/22

CPC classification number: C07H15/224

公开(公告)号：AU6600981A

公开(公告)日：1981-08-27

申请号：AU6600981

申请日：1981-01-06

Applicant: ABBOTT LAB

Inventor： BODOR N S ,  FREIBERG L A

IPC: A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08

Abstract: High water-soluble erythromycin A derivatives wherein the desosamine moiety is quaternized with an acyloxy-, benzoyloxy- or alkoxycarbonyl-(or carboxy)-acylmethyl iodide, bromine or chloride and esterified in the 2-position with loweralkyl or -(CH2)nCO2R sec , wherein R sec is H, loweralkyl or substituted loweralkyl and n is an integer from 1-5. These new esters readily convert to erythromycin A upon administration to warm-blooded animals.

公开(公告)号：SE7812825L

公开(公告)日：1979-06-22

申请号：SE7812825

申请日：1978-12-13

Applicant: ABBOTT LAB

Inventor： DUNNIGAN D A ,  MARTIN J R ,  TADANIER J S ,  FREIBERG L A

IPC: C07H15/224 ,  C07H15/22