公开(公告)号：WO9429456A3

公开(公告)日：1995-03-02

申请号：PCT/US9405920

申请日：1994-05-25

Applicant: ABBOTT LAB

Inventor： STEFFY KEVIN R ,  KATI WARREN M ,  KATZ LEONARD ,  MCGONIGAL THOMAS P ,  SARTHY APARNA V ,  SCHOEN SHARON E

IPC: C12N15/09 ,  C07K16/08 ,  C12N1/19 ,  C12N1/21 ,  C12N9/50 ,  C12N15/57 ,  C12R1/19 ,  C12R1/865 ,  C12R1/92 ,  C12N5/10

CPC classification number: C07K16/087 ,  C12N9/503

Abstract: Protease activity associated with herpes simplex virus (HSV) type 2 was identified. The complete nucleotide and amino acid sequence of the protease was determined. The HSV-2 nucleic acid segment encoding the protease substrate ICP35 was also sequenced. Recombinant vectors and host cells for expressing the protease are also described.

公开(公告)号：WO0234909A3

公开(公告)日：2003-11-13

申请号：PCT/US0148040

申请日：2001-10-26

Applicant: ABBOTT LAB

Inventor： STEWART KENT D ,  STEFFY KEVIN R ,  KEMPF DALE J ,  HARRIS KEVIN S ,  HUTH JEFFREY R ,  STOLL VINCENT S ,  HARLAN JOHN E ,  NG IOK C ,  BETZ STEPHEN F

IPC: G01N33/566 ,  C07K14/16 ,  C07K16/10 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12P21/02 ,  C40B30/04 ,  G01N33/15 ,  G01N33/50 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  C12N15/11

CPC classification number: C40B30/04 ,  C07K14/005 ,  C07K2319/00 ,  C12N2740/16122 ,  G01N33/56988 ,  G01N33/6842 ,  G01N33/6845 ,  G01N2500/04

Abstract: The subject invention encompasses novel proteins related to the human immunodeficiency virus (HIV-1) gp41 protein and to methods of use thereof. For example, the proteins may be utilized in the screening of anti-HIV compounds.

Abstract translation: 本发明涵盖与人免疫缺陷病毒（HIV-1）gp41蛋白相关的新型蛋白质及其使用方法。 例如，蛋白质可用于筛选抗HIV化合物。

公开(公告)号：CA2427312A1

公开(公告)日：2002-05-02

申请号：CA2427312

申请日：2001-10-26

Applicant: ABBOTT LAB

Inventor： HUTH JEFFREY R ,  NG IOK C ,  HARLAN JOHN E ,  KEMPF DALE J ,  STOLL VINCENT S ,  BETZ STEPHEN F ,  HARRIS KEVIN S ,  STEWART KENT D ,  STEFFY KEVIN R

IPC: G01N33/566 ,  C07K14/16 ,  C07K16/10 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12P21/02 ,  C40B30/04 ,  G01N33/15 ,  G01N33/50 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  C12N15/11

Abstract: The subject invention encompasses novel proteins related to the human immunodeficiency virus (HIV-1) gp41 protein and to methods of use thereof. F or example, the proteins may be utilized in the screening of anti-HIV compounds .

公开(公告)号：MXPA03003696A

公开(公告)日：2005-01-25

申请号：MXPA03003696

申请日：2001-10-26

Applicant: ABBOTT LAB

Inventor： STEFFY KEVIN R

IPC: G01N33/566 ,  C07K14/16 ,  C07K16/10 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12P21/02 ,  C40B30/04 ,  G01N33/15 ,  G01N33/50 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  C12N15/11

Abstract: La invencion sujeto abarca proteinas novedosas con relacion a la proteina gp41 del virus de inmunodeficiencia humana (VIH-1) y a los metodos de uso de la misma. Por ejemplo, las proteinas pueden utilizarse en la seleccion de compuestos de anti-VIH.