公开(公告)号：WO0230959A3

公开(公告)日：2002-09-26

申请号：PCT/US0132121

申请日：2001-10-12

Applicant: ABBOTT LAB

Inventor： FESIK STEPHEN W ,  MEADOWS ROBERT P ,  BETZ STEPHEN P ,  LIU ZHIHONG ,  OLEJNICZAK EDWARD T ,  SUN CHAOHONG

IPC: C07K14/47 ,  C07K14/81 ,  G01N33/68

CPC classification number: C07K14/8139 ,  C07K14/4702

Abstract: The present invention relates to peptides derived from the wildtype human smac (DIABLO) protein which binds to a member of an IAP family member. The peptides of the present invention can be used in an assay to identify candidate substances which induce or promote apoptosis in cells.

Abstract translation: 本发明涉及衍生自与IAP家族成员结合的野生型人类smac（DIABLO）蛋白质的肽。 本发明的肽可用于测定诱导或促进细胞凋亡的候选物质。