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1.发明申请NUTRITIONAL COMPOSITION HAVING LIPOPHILIC COMPOUNDS WITH IMPROVED SOLUBILITY AND BIOAVAILABILITY 审中-公开具有改善溶解性和生物利用度的脂质化合物的营养组合物
公开(公告)号：WO2015031657A1
公开(公告)日：2015-03-05
申请号：PCT/US2014/053230
申请日：2014-08-28
Applicant: ABBOTT LABORATORIES
Inventor： JOHNS, Paul , VURMA, Mustafa , ALBRECHT, Daniel , DEMICHELE, Stephen , KATZ, Gary , REDDY, Todime
CPC classification number: A23L33/115 , A23C9/1526 , A23C9/1528 , A23L33/15 , A23L33/155 , A23L33/17 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2250/182 , A23V2250/192 , A23V2250/211 , A23V2250/71
Abstract: Disclosed herein is a nutritional composition having at least one protein, at least one fat, and at least one lipophilic compound, the composition comprising at least one assembly comprising at least one hydrophobic protein, monoglycerides and diglycerides ("MDG") and at least one lipophilic compound, wherein at least 1% of the total MDG in the nutritional composition remains in the aqueous phase after centrifugation at 100,000 x g for 1 hour at 20°C.
Abstract translation: 本文公开了具有至少一种蛋白质，至少一种脂肪和至少一种亲脂性化合物的营养组合物，所述组合物包含至少一种包含至少一种疏水蛋白，单酸甘油酯和甘油二酯（“MDG”）的组合物和至少一种 亲脂性化合物，其中营养组合物中总MDG的至少1％在20℃下以100,000×g离心1小时后保持在水相中。
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2.发明申请INFANT FORMULA COMPRISING HUMAN MILK OLIGOSACCHARIDES, POLYUNSATURATED FATTY ACIDS, NUCLEOTIDES, AND LUTEIN 审中-公开包含人乳酪寡糖，聚氧乙烯脂肪酸，核苷酸和红蛋白的婴儿配方
公开(公告)号：WO2016086157A1
公开(公告)日：2016-06-02
申请号：PCT/US2015/062721
申请日：2015-11-25
Applicant: ABBOTT LABORATORIES
Inventor： ALBRECHT, Daniel , ENGLE, Mark
IPC: A61K31/702 , A61P25/28 , A23L33/00 , A23L33/10 , A23L33/115 , A23L33/12 , A23L33/13 , A23L33/15 , A23L33/21
CPC classification number: A23L33/40 , A23L33/10 , A23L33/115 , A23L33/12 , A23L33/13 , A23L33/15 , A23L33/17 , A23L33/28 , A23L33/30 , A23V2002/00 , A61K9/0095 , A61K31/047 , A61K31/07 , A61K31/202 , A61K31/355 , A61K31/702 , A61K31/708 , A61K2300/00
Abstract: Infant formulas that include at least one human milk oligosaccharide selected from 2'-fucosyllactose (2'-FL) and lacto-N-neotetraose (LNnT), polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and arachidonic acid (AA), where the AA and DHA are present in an n-6/n-3 ratio of between 1 and 1.8, at least 30 mg/L of nucleotides, where the nucleotides include inosine monophosphate, and at least 30 µg/L of lutein are disclosed. Also provided are methods of use of the infant formulas for improving at least one of cognition, learning, and memory in an infant. The methods include administering the infant formulas to an infant.
Abstract translation: 包含至少一种选自2'-岩藻糖基乳糖（2'-FL）和乳-N-新四糖（LNnT），多不饱和脂肪酸（PUFA）二十二碳六烯酸（DHA）和花生四烯酸（AA））的人乳寡糖的婴儿配方， 其中AA和DHA以1至1.8之间的n-6 / n-3比率存在，至少30mg / L的核苷酸，其中核苷酸包括肌苷单磷酸酯和至少30μg/ L的叶黄素 。 还提供了使用婴儿配方来改善婴儿的认知，学习和记忆中的至少一种的方法。 所述方法包括向婴儿施用婴儿配方奶粉。
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3.发明申请INFANT FORMULA WITH RRR-ALPHA-TOCOPHEROL, 2'-FUCOSYLLACTOSE, AND A PROBIOTIC 审中-公开含有RRR-ALPHA-TOCOPHEROL，2'-FUCOSLLACTOSE和PROBIOTIC的婴儿配方
公开(公告)号：WO2016086151A1
公开(公告)日：2016-06-02
申请号：PCT/US2015/062712
申请日：2015-11-25
Applicant: ABBOTT LABORATORIES
Inventor： ALBRECHT, Daniel , ENGLE, Mark
IPC: A61K31/702 , A61P25/28 , A23L33/15 , A23L33/135 , A23L33/21 , A23L33/00 , A23L33/10
CPC classification number: A61K35/747 , A23L33/10 , A23L33/135 , A23L33/15 , A23L33/28 , A23L33/40 , A23V2002/00 , A61K31/355 , A61K31/702 , A61K31/7024 , A61K35/745 , A23V2200/3204 , A23V2200/322 , A23V2250/712 , A61K2300/00
Abstract: Infant formulas that include a combination of RRR-alpha-tocopherol, 2'-fucosyllactose, and at least one probiotic from the Lactobacillus or the Bifidobacterium genera are disclosed. Also provided are methods of use of the infant formulas for improving at least one of cognition, learning, and memory in an infant. The methods include administering the infant formulas to an infant.
Abstract translation: 公开了包括来自乳杆菌属或双歧杆菌属的RRR-α-生育酚，2'-岩藻糖基乳糖和至少一种益生菌的组合的婴儿配方。 还提供了使用婴儿配方来改善婴儿的认知，学习和记忆中的至少一种的方法。 所述方法包括向婴儿施用婴儿配方奶粉。
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4.发明申请NUTRITIONAL COMPOSITION HAVING LIPOPHILIC COMPOUNDS WITH IMPROVED SOLUBILITY AND BIOAVAILABILITY 审中-公开具有改善溶解性和生物利用度的脂质化合物的营养组合物
公开(公告)号：WO2015031637A1
公开(公告)日：2015-03-05
申请号：PCT/US2014/053197
申请日：2014-08-28
Applicant: ABBOTT LABORATORIES
Inventor： JOHNS, Paul , VURMA, Mustafa , ALBRECHT, Daniel , DEMICHELE, Stephen , KATZ, Gary , REDDY, Todime
IPC: A23L1/30 , A23L1/302 , A23C9/20 , A23L1/29 , A61K31/593
CPC classification number: A23L33/115 , A23C9/1526 , A23C9/1528 , A23L33/15 , A23L33/155 , A23L33/17 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2250/182 , A23V2250/192 , A23V2250/211 , A23V2250/71
Abstract: Disclosed herein is a nutritional composition having at least one protein, at least one fat, and at least one lipophilic compound, the composition comprising at least one assembly comprising at least one hydrophobic protein, monoglycerides and diglycerides ("MDG") and at least one lipophilic compound, wherein at least 1% of the total MDG in the nutritional composition remains in the aqueous phase after centrifugation at 100,000 x g for 1 hour at 20 °C.
Abstract translation: 本文公开了具有至少一种蛋白质，至少一种脂肪和至少一种亲脂性化合物的营养组合物，所述组合物包含至少一种包含至少一种疏水蛋白，单酸甘油酯和甘油二酯（“MDG”）的组合物和至少一种 亲脂性化合物，其中营养组合物中总MDG的至少1％在20℃下以100,000×g离心1小时后保持在水相中。
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5.发明公开INFANT FORMULA COMPRISING HUMAN MILK OLIGOSACCHARIDES, POLYUNSATURATED FATTY ACIDS, NUCLEOTIDES, AND LUTEIN 审中-公开包含人乳寡糖，多不饱和脂肪酸，核苷酸和叶黄素的婴儿配方食品
公开(公告)号：EP3223825A1
公开(公告)日：2017-10-04
申请号：EP15805081.5
申请日：2015-11-25
Applicant: Abbott Laboratories
Inventor： ALBRECHT, Daniel , ENGLE, Mark
IPC: A61K31/702 , A61P25/28 , A23L33/00 , A23L33/10 , A23L33/115 , A23L33/12 , A23L33/13 , A23L33/15 , A23L33/21
CPC classification number: A23L33/40 , A23L33/10 , A23L33/115 , A23L33/12 , A23L33/13 , A23L33/15 , A23L33/17 , A23L33/28 , A23L33/30 , A23V2002/00 , A61K9/0095 , A61K31/047 , A61K31/07 , A61K31/202 , A61K31/355 , A61K31/702 , A61K31/708 , A61K2300/00
Abstract: Infant formulas that include at least one human milk oligosaccharide selected from 2′-fucosyllactose (2′-FL) and lacto-N-neotetraose (LNnT), polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and arachidonic acid (AA), where the AA and DHA are present in an n-6/n-3 ratio of between 1 and 1.8, at least 30 mg/L of nucleotides, where the nucleotides include inosine monophosphate, and at least 30 μg/L of lutein are disclosed. Also provided are methods of use of the infant formulas for improving at least one of cognition, learning, and memory in an infant. The methods include administering the infant formulas to an infant.
Abstract translation: 包含至少一种选自2'-岩藻糖基乳糖（2'-FL）和乳糖-N-新四糖（LNnT），多不饱和脂肪酸（PUFA），二十二碳六烯酸（DHA）和花生四烯酸（AA）的人乳寡糖的婴儿配方食品， 其中AA和DHA以1和1.8之间的n-6 / n-3比例存在，公开了至少30mg / L核苷酸，其中核苷酸包括肌苷一磷酸盐和至少30μg/ L叶黄素 。 还提供了使用婴儿配方用于改善婴儿中认知，学习和记忆中的至少一种的方法。 该方法包括将婴儿配方食品给予婴儿。
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Patent Agency Ranking6.发明授权
公开(公告)号：EP3091860B1
公开(公告)日：2019-03-27
申请号：EP14762193.2
申请日：2014-08-28
Applicant: Abbott Laboratories
Inventor： JOHNS, Paul , VURMA, Mustafa , ALBRECHT, Daniel , DEMICHELE, Stephen , KATZ, Gary , REDDY, Todime
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7.发明公开INFANT FORMULA WITH RRR-ALPHA-TOCOPHEROL, 2'-FUCOSYLLACTOSE, AND A PROBIOTIC 审中-公开有RRR-ALPHA-生育酚，2'-氟胞苷和一种益生菌的婴儿体重
公开(公告)号：EP3223826A1
公开(公告)日：2017-10-04
申请号：EP15805721.6
申请日：2015-11-25
Applicant: Abbott Laboratories
Inventor： ALBRECHT, Daniel , ENGLE, Mark
IPC: A61K31/702 , A61P25/28 , A23L33/15 , A23L33/135 , A23L33/21 , A23L33/00 , A23L33/10
CPC classification number: A61K35/747 , A23L33/10 , A23L33/135 , A23L33/15 , A23L33/28 , A23L33/40 , A23V2002/00 , A61K31/355 , A61K31/702 , A61K31/7024 , A61K35/745 , A23V2200/3204 , A23V2200/322 , A23V2250/712 , A61K2300/00
Abstract: Infant formulas that include a combination of RRR-alpha-tocopherol, 2′-fucosyllactose, and at least one probiotic from the Lactobacillus or the Bifidobacterium genera are disclosed. Also provided are methods of use of the infant formulas for improving at least one of cognition, learning, and memory in an infant. The methods include administering the infant formulas to an infant.
Abstract translation: 公开了包含RRR-α-生育酚，2'-岩藻糖基乳糖和至少一种来自乳酸杆菌或双歧杆菌属的益生菌的组合的婴儿配方食品。 还提供了使用婴儿配方用于改善婴儿中认知，学习和记忆中的至少一种的方法。 该方法包括将婴儿配方食品给予婴儿。
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8.发明公开NUTRITIONAL COMPOSITION HAVING LIPOPHILIC COMPOUNDS WITH IMPROVED SOLUBILITY AND BIOAVAILABILITY 审中-公开具有改善溶解度和生物利用度的亲脂性化合物的营养组合物
公开(公告)号：EP3091860A1
公开(公告)日：2016-11-16
申请号：EP14762193.2
申请日：2014-08-28
Applicant: Abbott Laboratories
Inventor： JOHNS, Paul , VURMA, Mustafa , ALBRECHT, Daniel , DEMICHELE, Stephen , KATZ, Gary , REDDY, Todime
CPC classification number: A23L33/115 , A23C9/1526 , A23C9/1528 , A23L33/15 , A23L33/155 , A23L33/17 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2250/182 , A23V2250/192 , A23V2250/211 , A23V2250/71
Abstract: Disclosed herein is a nutritional composition having at least one protein, at least one fat, and at least one lipophilic compound, the composition comprising at least one assembly comprising at least one hydrophobic protein, monoglycerides and diglycerides (“MDG”) and at least one lipophilic compound, wherein at least 1% of the total MDG in the nutritional composition remains in the aqueous phase after centrifugation at 100,000×g for 1 hour at 20° C.
Abstract translation: 本文公开了具有至少一种蛋白质，至少一种脂肪和至少一种亲脂性化合物的营养组合物，所述组合物包含至少一种包含至少一种疏水性蛋白质，甘油单酯和甘油二酯（“MDG”）和至少一种 亲脂性化合物，其中在20℃以100,000×g离心1小时后，营养组合物中总MDG的至少1％保留在水相中。
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9.发明授权
公开(公告)号：EP3043658B1
公开(公告)日：2019-11-20
申请号：EP14761548.8
申请日：2014-08-28
Applicant: Abbott Laboratories
Inventor： JOHNS, Paul , VURMA, Mustafa , ALBRECHT, Daniel , DEMICHELE, Stephen , KATZ, Gary , REDDY, Todime
IPC: A23L33/10 , A23L33/15 , A23C9/20 , A23L33/00 , A61K31/593
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10.发明公开NUTRITIONAL COMPOSITION HAVING LIPOPHILIC COMPOUNDS WITH IMPROVED SOLUBILITY AND BIOAVAILABILITY 审中-公开具有改善的溶解度和生物利用度食品组合物的亲脂性化合物
公开(公告)号：EP3043658A1
公开(公告)日：2016-07-20
申请号：EP14761548.8
申请日：2014-08-28
Applicant: Abbott Laboratories
Inventor： JOHNS, Paul , VURMA, Mustafa , ALBRECHT, Daniel , DEMICHELE, Stephen , KATZ, Gary , REDDY, Todime
IPC: A23L33/10 , A23L33/15 , A23C9/20 , A23L33/00 , A61K31/593
Abstract: Disclosed herein is a nutritional composition having at least one protein, at least one fat, and at least one lipophilic compound, the composition comprising at least one assembly comprising at least one hydrophobic protein, monoglycerides and diglycerides (“MDG”) and at least one lipophilic compound, wherein at least 1% of the total MDG in the nutritional composition remains in the aqueous phase after centrifugation at 100,000×g for 1 hour at 20° C.
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