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公开(公告)号：WO2017004463A1
公开(公告)日：2017-01-05
申请号：PCT/US2016/040579
申请日：2016-06-30
Applicant: ABBOTT LABORATORIES
Inventor： HUFF, Jeffrey B. , HAYDEN, Mark A. , KARABATSOS, Peter J. , SCHAPALS, Andrew S. , MUERHOFF, Anthony S. , BOGDAN, Maria Felicia , LEARY, Thomas , HOLETS-MCCORMACK, Shelley R. , LAURENSON, Sophie , FISCHER, Andrew T. , HAACK, Richard , HERSHBERGER, Stefan , HOUSE, Dustin , QIAO, Lei , MURPHY, M. Shawn , POPE, Mark R. , PRIETO-BALLENGEE, Edna M. , RUAN, QiaoQiao , SONI, Pathik , TETIN, Sergey , YARNELL, Lyle
IPC: G01N33/53 , G01N33/487 , G01N33/543
CPC classification number: G01N33/54306 , G01N33/48721 , G01N33/5308 , G01N2458/10
Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. Other aspects of the methods use a phage conjugate as the detection moiety. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.
Abstract translation: 公开了使用纳米孔分析物分析的方法，装置和系统。 方法，装置和系统利用第一和第二结合成员，每个结合成员都特异性结合生物样品中的分析物。 该方法还包括检测和/或计数连接到第二结合成员的可切割标签，并将标签的存在和/或数量与分析物的存在和/或浓度相关联。 方法的某些方面不涉及标签，而是可以直接检测/量化第二结合成员。 方法的其他方面使用噬菌体缀合物作为检测部分。 检测和/或计数可以通过将标签/第二结合部件移位通过纳米孔来进行。 还提供了被编程以执行所公开的方法的设备和系统。
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公开(公告)号：WO2017223214A1
公开(公告)日：2017-12-28
申请号：PCT/US2017/038568
申请日：2017-06-21
Applicant: ABBOTT LABORATORIES
Inventor： YARNELL, Lyle , MURPHY, Michael Shawn
Abstract: Liquid level sensing apparatus are disclosed. An example liquid level sensing apparatus includes a cannula defining a body having a tip and an access channel. The tip to pierce a container, where the cannula is to be at least partially positioned in the container when the tip pierces the container. A probe is to be positioned in the access channel. A signal source is to electrically energize the probe and the cannula to cause the probe to emit a first signal and cause the cannula to emit a second signal.
Abstract translation: 公开了液位传感设备。 示例液位感测装置包括套管，该套管限定具有尖端和进入通道的主体。 刺穿容器的尖端，当尖端刺穿容器时，插管至少部分地位于容器中。 探针将被定位在访问通道中。 信号源是对探针和套管进行电激励以使探针发出第一信号并使套管发出第二信号。
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Patent Agency Ranking3.发明申请
公开(公告)号：WO2018119227A1
公开(公告)日：2018-06-28
申请号：PCT/US2017/067890
申请日：2017-12-21
Applicant: ABBOTT LABORATORIES
Inventor： FRITCHIE, Patrick , SONI, Pathik , QIAO, Lei , HOUSE, Dustin , YARNELL, Lyle , PRIETO-BALLENGEE, Edna , FORSYTHE, Cathy , MURPHY, Michael Shawn , FISCHER, Andrew , SHARMA, Akanksha , ESPOSITO, Joseph , EFFINGER, Matt , FUTER, Michael
Abstract: Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit. The example system includes a controller to drive the tank circuit to selectively oscillate at a resonant frequency for the tank circuit to inductively heat a work piece disposed proximate to the tank circuit.
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公开(公告)号：WO2016161402A1
公开(公告)日：2016-10-06
申请号：PCT/US2016/025787
申请日：2016-04-02
Applicant: ABBOTT LABORATORIES
Inventor： HUFF, Jeffrey B. , HAYDEN, Mark A. , KARABATSOS, Peter J. , SCHAPALS, Andrew S. , MUERHOFF, Anthony S. , BOGDAN, Felicia , LEARY, Thomas , HOLETS-MCCORMACK, Shelley R. , LAURENSON, Sophie , FISCHER, Andrew T. , HAACK, Richard , HERSHBERGER, Stefan , HOUSE, Dustin , QIAO, Lei , MURPHY, M. Shawn , POPE, Mark R. , PRIETO-BALLENGEE, Edna M. , RUAN, QiaoQiao , SONI, Pathik , TETIN, Sergey , YARNELL, Lyle
IPC: G01N33/53 , G01N33/487 , G01N33/543
CPC classification number: G01N33/48721 , B01L3/502761 , B01L2300/0645 , B01L2400/0406 , G01N33/5308 , G01N33/54306 , G01N2458/10
Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.
Abstract translation: 公开了使用纳米孔分析物分析的方法，装置和系统。 方法，装置和系统利用第一和第二结合成员，每个结合成员都特异性结合生物样品中的分析物。 该方法还包括检测和/或计数连接到第二结合成员的可切割标签，并将标签的存在和/或数量与分析物的存在和/或浓度相关联。 方法的某些方面不涉及标签，而是可以直接检测/量化第二结合成员。 检测和/或计数可以通过将标签/第二结合部件移位通过纳米孔来进行。 还提供了被编程以执行所公开的方法的设备和系统。
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公开(公告)号：EP3839507A1
公开(公告)日：2021-06-23
申请号：EP21156369.7
申请日：2016-04-02
Applicant: Abbott Laboratories
Inventor： HUFF, Jeffrey B , HAYDEN, Mark A , KARABATSOS, Peter J , SCHAPALS, Andrew S , MUERHOFF, Anthony S , BOGDAN, Felicia , LEARY, Thomas , HOLETS-MCCORMACK, Shelley R , LAURENSON, Sophie , FISCHER, Andrew T , HAACK, Richard , HERSHBERGER, Stefan , HOUSE, Dustin , QIAO, Lei , MURPHY, M. Shawn , POPE, Mark R. , PRIETO-BALLENGEE, Edna M. , RUAN, QiaoQiao , SONI, Pathik , TETIN, Sergey , YARNELL, Lyle
IPC: G01N33/53 , G01N33/487 , G01N33/543
Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.
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6.发明公开
公开(公告)号：EP3560278A1
公开(公告)日：2019-10-30
申请号：EP17842406.5
申请日：2017-12-21
Applicant: Abbott Laboratories
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公开(公告)号：EP3278108A1
公开(公告)日：2018-02-07
申请号：EP16717521.5
申请日：2016-04-02
Applicant: Abbott Laboratories
Inventor： HUFF, Jeffrey B. , HAYDEN, Mark A. , KARABATSOS, Peter J. , SCHAPALS, Andrew S. , MUERHOFF, Anthony S. , BOGDAN, Felicia , LEARY, Thomas , HOLETS-MCCORMACK, Shelley R. , LAURENSON, Sophie , FISCHER, Andrew T. , HAACK, Richard , HERSHBERGER, Stefan , HOUSE, Dustin , QIAO, Lei , MURPHY, M. Shawn , POPE, Mark R. , PRIETO-BALLENGEE, Edna M. , RUAN, QiaoQiao , SONI, Pathik , TETIN, Sergey , YARNELL, Lyle
IPC: G01N33/53 , G01N33/487 , G01N33/543
CPC classification number: G01N33/48721 , B01L3/502761 , B01L2300/0645 , B01L2400/0406 , G01N33/5308 , G01N33/54306 , G01N2458/10
Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.
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