公开(公告)号：AU611950B2

公开(公告)日：1991-06-27

申请号：AU2306388

申请日：1988-09-12

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MASUOKA TOSHIO ,  HIRASA OKIHIKO ,  ONISHI MAKOTO ,  SEITA YUKIO

IPC: B01D63/08 ,  B01D67/00 ,  B01D61/00 ,  B01D71/26 ,  A61K35/14

Abstract: A hydrophilic porous membrane having fine network structure and substantially comprising polypropylene is disclosed, which has on at least one side thereof a surface layer of about the same network structure as that of the inner portion, in which a hydrophilic polymer is chemically bonded to the membrane surface and fine pore surface, and which has an average pore size of 0.1 to 2.0 mu m, a bubble point of up to 2.0 kg/cm , voids of 60 to 85 %, and a water-penetrating amount of 2 ml/min.mmHg.m or more. This membrane is useful as a hydrophilic, plasma-separating membrane. A process for its production and a plasma-separating apparatus containing this membrane in a housing are also disclosed.

公开(公告)号：DE3769011D1

公开(公告)日：1991-05-08

申请号：DE3769011

申请日：1987-05-07

Applicant: AGENCY IND SCIENCE TECHN ,  TERUMO CORP

Inventor： MASUOKA TOSHIO ,  HIRASA OKIHIKO ,  SUDA YOSHIO ,  ONISHI MAKOTO ,  SEITA YUKIO

IPC: A61M1/22 ,  A61M1/16 ,  B01D63/08 ,  B01D67/00 ,  B01D71/82 ,  D06M13/02 ,  D06M13/224 ,  D06M13/322 ,  D06M13/402 ,  D06M13/41 ,  D06M14/00 ,  D06M101/00 ,  D06M101/16 ,  D06M101/18 ,  B01D71/00

Abstract: A hydrophilic porous membrane having graft chains of a hydrophilic monomer formed on the surface of a hydrophobic porous membrane so as to impart to the surface perfect hydrophilicity such that the produced membrane, when wetted, exhibits as swelling ratio of not more than 1% and a bubble point in the range of 0.5 to 8 kg/cm . The hydrophilic porous membrane is produced by irradiating the hydrophobic porous membrane with plasma, feeding the hydrophilic monomer in a gaseous state, and allowing the hydrophilic monomer to be graft polymerized on the surface of the porous membrane. A plasma separator is obtained by using the aforementioned hydrophilic porous membrane as a plasma separation membrane.

公开(公告)号：AU7257587A

公开(公告)日：1987-12-10

申请号：AU7257587

申请日：1987-05-05

Applicant: AGENCY IND SCIENCE TECHN ,  TERUMO CORP

Inventor： MASUOKA TOSHIO ,  SUDA YOSHIO ,  SEITA YUKIO ,  HIRASA OKIHIKO ,  ONISHI MAKOTO

IPC: C08J7/18 ,  B01D13/04 ,  B01D13/00

公开(公告)号：CA1325405C

公开(公告)日：1993-12-21

申请号：CA577109

申请日：1988-09-12

Applicant: AGENCY IND SCIENCE TECHN ,  TERUMO CORP

Inventor： MASUOKA TOSHIO ,  HIRASA OKIHIKO ,  ONISHI MAKOTO ,  SEITA YUKIO

IPC: B01D63/08 ,  B01D67/00 ,  B01D69/12 ,  A61M1/34

Abstract: A porous hydrophilic polypropylene membrane possessing a fine reticular structure, which is characterized by the fact that at least either of the opposite surfaces of membrane forms a surface layer of a reticular structure substantially equal to that in the interior of membrane, the membrane surfaces and the surfaces of pores in the membrane have a hydrophilic polymer chemically bonded thereto, and the membrane is composed substantially of a polypropylene possessing an average pore diameter in the range 0.1 to 2.0 .mu.m, a bubble point of not more than 2.0 kg/cm2, a porosity in the range of 60 to 85%, and a water permeability of not less than 2 ml/min.mmHg.m2, a method for the production thereof, and a blood plasma separation apparatus incorporating such membranes in a housing are disclosed.

公开(公告)号：CA1313441C

公开(公告)日：1993-02-09

申请号：CA536428

申请日：1987-05-05

Applicant: AGENCY IND SCIENCE TECHN ,  TERUMO CORP

Inventor： MASUOKA TOSHIO ,  HIRASA OKIHIKO ,  SUDA YOSHIO ,  ONISHI MAKOTO ,  SEITA YUKIO

IPC: A61M1/22 ,  A61M1/16 ,  B01D63/08 ,  B01D67/00 ,  B01D71/82 ,  D06M13/02 ,  D06M13/224 ,  D06M13/322 ,  D06M13/402 ,  D06M13/41 ,  D06M14/00 ,  D06M101/00 ,  D06M101/16 ,  D06M101/18 ,  C08J5/22

Abstract: A hydrophilic porous membrane has graft chains of a hydrophilic monomer formed on the surface of a hydrophobic porous membrane so as to impart to the surface perfect hydrophilicity such that the produced membrane, when wetted, exhibits a swelling ratio of not more than 1% and a bubble point in the range of 0.5 to 8 kg/cm2. The hydrophilic porous membrane is produced by irradiating the hydrophobic porous membrane with plasma, feeding the hydrophilic monomer in a gaseous state, and allowing the hydrophilic monomer to be graft polymerized on the surface of the porous membrane. A plasma separator is obtained by using the aforementioned hydrophilic porous membrane as a plasma separation membrane.

公开(公告)号：AU580212B2

公开(公告)日：1989-01-05

申请号：AU7257587

申请日：1987-05-05

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MASUOKA TOSHIO ,  SUDA MASAO ,  SEITA YUKIO ,  HIRASA OKIHIKO ,  ONISHI MAKOTO

IPC: C08J7/18 ,  B01D13/04 ,  B01D13/00

公开(公告)号：DE3883777T2

公开(公告)日：1994-01-27

申请号：DE3883777

申请日：1988-09-12

Applicant: AGENCY IND SCIENCE TECHN ,  TERUMO CORP

Inventor： MASUOKA TOSHIO ,  HIRASA OKIHIKO ,  ONISHI MAKOTO ,  SEITA YUKIO

IPC: B01D63/08 ,  B01D67/00 ,  B01D69/00 ,  A61M1/16 ,  A61M1/34

Abstract: A hydrophilic porous membrane having fine network structure and substantially comprising polypropylene is disclosed, which has on at least one side thereof a surface layer of about the same network structure as that of the inner portion, in which a hydrophilic polymer is chemically bonded to the membrane surface and fine pore surface, and which has an average pore size of 0.1 to 2.0 mu m, a bubble point of up to 2.0 kg/cm , voids of 60 to 85 %, and a water-penetrating amount of 2 ml/min.mmHg.m or more. This membrane is useful as a hydrophilic, plasma-separating membrane. A process for its production and a plasma-separating apparatus containing this membrane in a housing are also disclosed.