公开(公告)号：JP2000086566A

公开(公告)日：2000-03-28

申请号：JP25309699

申请日：1999-09-07

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  DIETMAR WELLER ,  BOCKSTIEGEL BERNHARD DR ,  REIMER KLAUS ,  KAIBEL GERD DR ,  JAEDICKE HAGEN DR

IPC: B01J31/14 ,  B01D3/00 ,  B01D3/14 ,  B01D3/32 ,  B01J10/00 ,  B01J19/24 ,  C07B61/00 ,  C07C45/67 ,  C07C45/68 ,  C07C45/82 ,  C07C49/203 ,  C07C67/54 ,  C07C69/72

Abstract: PROBLEM TO BE SOLVED: To continuously produce an unsaturated ketone in high yield for a short time in a single reactor without using a medium-boiling material by reacting an unsaturated alcohol with an alkyl acetoacetate in the presence of an organic aluminum compound. SOLUTION: The purpose of this invention is achieved by reacting an unsaturated alcohol of formula I [R1 is a 1-4C alkyl; R2 is a (methoxy-substituted) (1-37C) aliphatic hydrocarbon group or the like] with an alkyl acetoacetate of formula II (R3 is a 1-5C alkyl) on the internal structure of a rectifier to form an acetoacetate of an unsaturated alcohol, by separating an alcohol of the formula R3-OH from the overhead flow of the rectifier, and (A) by making the resultant acetoacetate of an alcohol of formula I rearrange into an unsaturated ketone of formula III in the presence of an organic aluminum compound (pref. an aluminum trialkoxide) in the lower part of the rectifier and/or (B) by feeding carbon dioxide formed each time at the bottom of the rectifier to the overhead flow through the rectifier and by separating an unsaturated ketone of formula III from the rectifier through the bottom.

公开(公告)号：JP2000178221A

公开(公告)日：2000-06-27

申请号：JP32563599

申请日：1999-11-16

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  DIETMAR WELLER ,  RHEUDE UDO ,  KAIBEL GERD ,  KRUG THOMAS ,  SPISKE LUISE ,  HAGEN IEEDIKKE

IPC: B01J31/14 ,  C07B61/00 ,  C07C45/67 ,  C07C45/74 ,  C07C49/203

Abstract: PROBLEM TO BE SOLVED: To produce the subject compound useful as an intermediate capable of producing isophytol of a precursor of an essential vitamin E in higher selectivity and higher space time yield by reacting a corresponding α,β-unsaturated alcohol with an alkyl acetoacetate by Carroll reaction. SOLUTION: (A) A corresponding α,β-unsaturated alcohol of formula II is reacted with (B) an alkyl acetoacetate of formula II (R3 is a 1-4C alkyl) in the presence of (C) 0.1-5 mol% organoaluminum compound as a catalyst in a reactor with a fractionating column while eliminating and continuously removing an alcohol of the formula R3-OH and produced carbon dioxide by distillation, and while introducing the components A and C to the reactor, further a calculated amount of the component B thereto preferably at 175-220 deg.C reaction temperature to provide the objective unsaturated ketone of formula I [a dotted line represents an additional C-C bond; R1 is a 1-4C alkyl; R2 is a 4-30C (un)saturated aliphatic or the like].

公开(公告)号：JP2000159721A

公开(公告)日：2000-06-13

申请号：JP33329199

申请日：1999-11-24

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  DIETMAR WELLER ,  KAIBEL GERD DR ,  HAGEN IEEDIKKE

IPC: B01J31/12 ,  B01J19/18 ,  C07B61/00 ,  C07C45/67 ,  C07C45/68 ,  C07C45/70 ,  C07C49/203

Abstract: PROBLEM TO BE SOLVED: To obtain an unsaturated ketone in a high yield by subjecting a specific α,β-unsaturated alcohol and an alkyl acetoacetate to a Carol reaction in the presence of an organic aluminum compound in the absence of a solvent at a specific reaction temperature. SOLUTION: This method for producing an unsaturated ketone of formula III (the dotted line is an additional C-C bond; R1 is a 1-2C alkyl; R2 is a 1-4C alkyl) comprises reacting (A) an α,β-unsaturated alcohol of formula I with (B) an alkyl acetoacetate of formula II in the presence of (C) an organic aluminum compound in a reactor system having a rectifier connected thereto, while continuously removing an alcohol of the formula: R3OH released from the alkyl acetoacetate during the release reaction and during the Carol reaction. In the reaction, the component A has a boiling point of

公开(公告)号：JPH11199537A

公开(公告)日：1999-07-27

申请号：JP29670098

申请日：1998-10-19

Applicant: BASF AG

Inventor： ETZRODT HEINZ ,  DIETMAR WELLER ,  OOST CARSTEN ,  JAEDICKE HAGEN ,  STROEZEL MANFRED ,  BOCKSTIEGEL BERNHARD DR

IPC: B01J31/02 ,  B01J31/14 ,  B01J31/22 ,  C07B61/00 ,  C07C45/67 ,  C07C45/68 ,  C07C49/203 ,  C07F5/06

Abstract: PROBLEM TO BE SOLVED: To easily obtain the subject compound useful as a precursor of vitamin E or the like with almost no production of byproducts by reacting a specific allyl alcohol with a specific diketene or the like in the presence of a specific aluminum catalyst by Carroll reaction. SOLUTION: This compound of formula III is obtained by reacting (A) an allyl alcohol of formula I (R is H or the like) with (B) a diketene or an acetoacetic acid alkyl ester of formula II (R is a 1-5C alkyl) by using (C) an aluminum compound which has one or more groups of acetoacetic acid alkyl ester and one or two of alkoxyl groups, or an acetoacetic acid alkyl ester group esterified with specifically secondary butanol or isobutanol or esterified with two or more different alkanols and is a stable liquid at ambient temperature, or a mixture of such aluminum compounds as a catalyst by a modified or unmodified Carroll reaction.