公开(公告)号：JP2000086566A

公开(公告)日：2000-03-28

申请号：JP25309699

申请日：1999-09-07

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  DIETMAR WELLER ,  BOCKSTIEGEL BERNHARD DR ,  REIMER KLAUS ,  KAIBEL GERD DR ,  JAEDICKE HAGEN DR

IPC: B01J31/14 ,  B01D3/00 ,  B01D3/14 ,  B01D3/32 ,  B01J10/00 ,  B01J19/24 ,  C07B61/00 ,  C07C45/67 ,  C07C45/68 ,  C07C45/82 ,  C07C49/203 ,  C07C67/54 ,  C07C69/72

Abstract: PROBLEM TO BE SOLVED: To continuously produce an unsaturated ketone in high yield for a short time in a single reactor without using a medium-boiling material by reacting an unsaturated alcohol with an alkyl acetoacetate in the presence of an organic aluminum compound. SOLUTION: The purpose of this invention is achieved by reacting an unsaturated alcohol of formula I [R1 is a 1-4C alkyl; R2 is a (methoxy-substituted) (1-37C) aliphatic hydrocarbon group or the like] with an alkyl acetoacetate of formula II (R3 is a 1-5C alkyl) on the internal structure of a rectifier to form an acetoacetate of an unsaturated alcohol, by separating an alcohol of the formula R3-OH from the overhead flow of the rectifier, and (A) by making the resultant acetoacetate of an alcohol of formula I rearrange into an unsaturated ketone of formula III in the presence of an organic aluminum compound (pref. an aluminum trialkoxide) in the lower part of the rectifier and/or (B) by feeding carbon dioxide formed each time at the bottom of the rectifier to the overhead flow through the rectifier and by separating an unsaturated ketone of formula III from the rectifier through the bottom.

公开(公告)号：JPH11199537A

公开(公告)日：1999-07-27

申请号：JP29670098

申请日：1998-10-19

Applicant: BASF AG

Inventor： ETZRODT HEINZ ,  DIETMAR WELLER ,  OOST CARSTEN ,  JAEDICKE HAGEN ,  STROEZEL MANFRED ,  BOCKSTIEGEL BERNHARD DR

IPC: B01J31/02 ,  B01J31/14 ,  B01J31/22 ,  C07B61/00 ,  C07C45/67 ,  C07C45/68 ,  C07C49/203 ,  C07F5/06

Abstract: PROBLEM TO BE SOLVED: To easily obtain the subject compound useful as a precursor of vitamin E or the like with almost no production of byproducts by reacting a specific allyl alcohol with a specific diketene or the like in the presence of a specific aluminum catalyst by Carroll reaction. SOLUTION: This compound of formula III is obtained by reacting (A) an allyl alcohol of formula I (R is H or the like) with (B) a diketene or an acetoacetic acid alkyl ester of formula II (R is a 1-5C alkyl) by using (C) an aluminum compound which has one or more groups of acetoacetic acid alkyl ester and one or two of alkoxyl groups, or an acetoacetic acid alkyl ester group esterified with specifically secondary butanol or isobutanol or esterified with two or more different alkanols and is a stable liquid at ambient temperature, or a mixture of such aluminum compounds as a catalyst by a modified or unmodified Carroll reaction.

公开(公告)号：JP2000178221A

公开(公告)日：2000-06-27

申请号：JP32563599

申请日：1999-11-16

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  DIETMAR WELLER ,  RHEUDE UDO ,  KAIBEL GERD ,  KRUG THOMAS ,  SPISKE LUISE ,  HAGEN IEEDIKKE

IPC: B01J31/14 ,  C07B61/00 ,  C07C45/67 ,  C07C45/74 ,  C07C49/203

Abstract: PROBLEM TO BE SOLVED: To produce the subject compound useful as an intermediate capable of producing isophytol of a precursor of an essential vitamin E in higher selectivity and higher space time yield by reacting a corresponding α,β-unsaturated alcohol with an alkyl acetoacetate by Carroll reaction. SOLUTION: (A) A corresponding α,β-unsaturated alcohol of formula II is reacted with (B) an alkyl acetoacetate of formula II (R3 is a 1-4C alkyl) in the presence of (C) 0.1-5 mol% organoaluminum compound as a catalyst in a reactor with a fractionating column while eliminating and continuously removing an alcohol of the formula R3-OH and produced carbon dioxide by distillation, and while introducing the components A and C to the reactor, further a calculated amount of the component B thereto preferably at 175-220 deg.C reaction temperature to provide the objective unsaturated ketone of formula I [a dotted line represents an additional C-C bond; R1 is a 1-4C alkyl; R2 is a 4-30C (un)saturated aliphatic or the like].

公开(公告)号：JPH11286459A

公开(公告)日：1999-10-19

申请号：JP2137299

申请日：1999-01-29

Applicant: BASF AG

Inventor： SCHWAB PETER DR ,  BREITSCHEIDEL BORIS DR ,  OOST CARSTEN ,  SCHULZ RALF DR ,  SCHULTZ MICHAEL

IPC: B01J23/36 ,  B01J23/46 ,  C07B61/00 ,  C07C2/10 ,  C07C4/10 ,  C07C6/04 ,  C07C11/06 ,  C07C11/08 ,  C08F2/00

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound in high yield by subjecting butenes to the mutual reaction over a metathesis catalyst including a metal compound in the transition group in the element periodic table. SOLUTION: In the presence of a metathesis catalyst containing at least one of metal compounds in the transition groups VIb, VIIb, or VIII in the periodic table, 1-butene is allowed to react with butene-2, subsequently formed propene and 2-pentene are separated. Then, the 2-pentene is allowed to react with ethene in the presence of the metathesis catalyst, subsequently formed propene and 1-butene are separated. At least part of the 1-butene product is exhausted and/or at least part of the isolated 1-butene is isomerized over an isomerization catalyst to form 2-butene. Then, the remaining 1-butene, the formed 2-butene and a part of the unreacting C4 fraction are recycled thereby obtaining propene or a combination thereof with 1-butene.

公开(公告)号：JP2003026620A

公开(公告)日：2003-01-29

申请号：JP2002130876

申请日：2002-05-02

Applicant: Basf Ag ,  ビーエーエスエフ アクチェンゲゼルシャフト

Inventor： ANSMANN ANDREAS ,  HENKELMANN JOCHEM ,  KINDLER ALOIS ,  ETZRODT HEINZ ,  OOST CARSTEN ,  STUTZ SUSANNE ,  TRAGUT CHRISTIAN ,  BOCKSTIEGEL BERNHARD ,  REIMER KLAUS ,  STROEZEL MANFRED ,  DOBLER WALTER

IPC: B01J23/44 ,  B01J23/50 ,  B01J35/04 ,  B01J35/06 ,  B01J37/02 ,  C07B61/00 ,  C07C29/17 ,  C07C29/32 ,  C07C29/42 ,  C07C33/02 ,  C07C33/048 ,  C07C45/48 ,  C07C45/62 ,  C07C45/67 ,  C07C49/203

CPC classification number: C07C49/203 ,  B01J23/44 ,  B01J23/50 ,  B01J35/04 ,  B01J35/06 ,  B01J37/0225 ,  C07C29/17 ,  C07C29/42 ,  C07C45/62 ,  C07C45/676 ,  C07C33/02 ,  C07C33/048 ,  C07C49/04

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a higher α,β-unsaturated alcohol in which engineering is easily performed. SOLUTION: This method for producing the alcohol represented by formula Ia or Ib [R is a 1-4C alkyl group; R is a group of formula II (R is hydrogen or a 1-4C alkyl group; a broken line is an additional double bond; and n is 0 or 1-6), hydrogen, or a saturated alkyl group] comprises (a) mono-ethynylating a ketone or formula: R -CO-CH2 -R in ammonia solution by using a basic catalyst, (b) optionally hydrogenating the alcohol of formula Ib on a Pd catalyst, and (c) subjecting the hydrogenated product to a purification distillation, and if necessary, reacting Ia or Ib produced by the steps (a) to (c) or by the steps (a) and (c) with an alkyl acetoacetate of formula IV [R is a 1-4C alkyl group], or a diketene to provide a methyl ketone, and using the ketone as a starting material in the steps (a) to (c).

Abstract translation: 要解决的问题：提供一种制造其中易于进行工程的较高α，β-不饱和醇的方法。 解决方案：用于制备由式Ia或Ib表示的醇的方法[R 1]是1-4C烷基; R 2是式II的基团（R 3是氢或1-4C烷基;虚线是另外的双键; n是0或1-6），氢或饱和烷基 基团]包括（a）通过使用碱性催化剂在氨溶液中使酮或式：R 1 -CO-CH 2 -R 2单乙炔基化，（b）任选地在Pd催化剂上氢化式Ib的醇 和（c）使氢化产物进行纯化蒸馏，如果需要，使由步骤（a）至（c）或步骤（a）和（c）制备的Ia或Ib与式 IV [R 5是1-4C烷基]或二烯酮以提供甲基酮，并且在步骤（a） - （c）中使用酮作为原料。

公开(公告)号：JP2000159721A

公开(公告)日：2000-06-13

申请号：JP33329199

申请日：1999-11-24

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  DIETMAR WELLER ,  KAIBEL GERD DR ,  HAGEN IEEDIKKE

IPC: B01J31/12 ,  B01J19/18 ,  C07B61/00 ,  C07C45/67 ,  C07C45/68 ,  C07C45/70 ,  C07C49/203

Abstract: PROBLEM TO BE SOLVED: To obtain an unsaturated ketone in a high yield by subjecting a specific α,β-unsaturated alcohol and an alkyl acetoacetate to a Carol reaction in the presence of an organic aluminum compound in the absence of a solvent at a specific reaction temperature. SOLUTION: This method for producing an unsaturated ketone of formula III (the dotted line is an additional C-C bond; R1 is a 1-2C alkyl; R2 is a 1-4C alkyl) comprises reacting (A) an α,β-unsaturated alcohol of formula I with (B) an alkyl acetoacetate of formula II in the presence of (C) an organic aluminum compound in a reactor system having a rectifier connected thereto, while continuously removing an alcohol of the formula: R3OH released from the alkyl acetoacetate during the release reaction and during the Carol reaction. In the reaction, the component A has a boiling point of

公开(公告)号：WO0116237A2

公开(公告)日：2001-03-08

申请号：PCT/EP0008412

申请日：2000-08-29

Applicant: BASF AG ,  THERRE JOERG ,  OOST CARSTEN

Inventor： THERRE JOERG ,  OOST CARSTEN

IPC: C07B61/00 ,  C07C45/60 ,  C07C45/82 ,  C07C47/12 ,  C09D

CPC classification number: C07C45/60 ,  Y02P20/127 ,  C07C47/12

Abstract: The invention relates to a method for the continuous production of glutaraldehyde by reacting an alkoxydihydropyrane of general formula (I), wherein R represents C1-C20 alkyl, with water at a temperature in the range of from 0 DEG C to 2000 DEG C and a pressure in the range of from 0.01 bar to 16 bar, and obtaining glutaraldehyde and the alcohol that corresponds to the alkoxy group. Water and alkoxyhydropyrane are continuously fed to a reaction column and at the top of the column a distillate enriched with the alcohol that corresponds to the alkoxy group and at the foot thereof a product enriched with glutaraldehyde is removed. The inventive method provides a simple means for producing glutaraldehyde or C-substituted glutaraldehydes continuously and with an improved purity which requires a minimum of equipment.

Abstract translation: 本发明涉及一种用于连续制备戊二醛的由式（I）的烷氧基​​二氢吡喃的反应，其中，R在从0℃至200℃，和压力的温度代表C1-C20烷基，与水的过程 在0.01巴至16巴的范围内，以形成戊二醛和相应的醇的烷氧基，其中的水和Alkoxyhydropyran连续供入反应塔和在塔的顶部，以使烷氧基对应的醇富集的馏出物和在底部的戊二醛 富氧产品被除去。 利用本发明的方法，有可能以简单的方式来制造戊二醛或C-取代戊二醛kontinierlich具有增加的纯度，需要的设备是低的。

公开(公告)号：DE50102763D1

公开(公告)日：2004-08-05

申请号：DE50102763

申请日：2001-09-19

Applicant: BASF AG

Inventor： KAIBEL GERD ,  OOST CARSTEN ,  STROEZEL MANFRED ,  MEYER GERALD ,  TRUEBENBACH PETER ,  SARTOR KARL-HEINZ ,  HENERS JUERGEN

IPC: B01D3/14 ,  B01D3/32 ,  B01D3/42 ,  C07B63/00 ,  C10G7/00 ,  C10G7/02 ,  C10G7/12

Abstract: A process is proposed for the separation of C 5+ cuts by distillation into a low-boiler (A), a medium-boiler (B) and a high-boiler fraction (C) in one or more dividing-wall columns (TK), in which a dividing wall (T) is arranged in the longitudinal direction of the column with formation of an upper, common column region ( 1 ), a lower, common column region ( 6 ), a feed part ( 2, 4 ) with rectifying section ( 2 ) and stripping section ( 4 ), and a withdrawal part ( 3, 5 ) with rectifying section ( 5 ) and stripping section ( 3 ), with feed of the C 5+ cut (A, B, C) into the central region of the feed part ( 2, 4 ), discharge of the high-boiler fraction (C) from the bottom of the column, discharge of the low-boiler fraction (A) via the top of the column, and discharge of the medium-boiler fraction (B) from the central region of the withdrawal part ( 3, 5 ), wherein the dividing ratio of the liquid reflux at the upper end of the dividing wall (T) is set in such a way that the proportion of high-boiling key components in the liquid reflux over the stripping section ( 3 ) of the withdrawal part at the upper end of the dividing wall (T) is from 10 to 80%, preferably from 30 to 50%, of the limit value allowed in the medium-boiler fraction (B), and wherein the heating power in the evaporator at the bottom of the dividing-wall column (TK) is set in such a way that the concentration of the low-boiling key components in the liquid at the lower end of the dividing wall (T) is from 10 to 80%, preferably from 30 to 50%, of the limit value allowed in the medium-boiler fraction (B).

公开(公告)号：AT224349T

公开(公告)日：2002-10-15

申请号：AT99122636

申请日：1999-11-13

Applicant: BASF AG

Inventor： OOST CARSTEN ,  STROEZEL MANFRED ,  ETZRODT HEINZ ,  WELLER DIETMAR ,  RHEUDE UDO ,  KAIBEL GERD ,  KRUG THOMAS ,  SPISKE LUISE ,  JAEDICKE HAGEN

IPC: B01J31/14 ,  C07B61/00 ,  C07C45/67 ,  C07C45/74 ,  C07C49/203

Abstract: Preparation of unsaturated ketones by reaction of the corresponding alpha , beta -unsaturated alcohol with an alkyl acetoacetate compound in the presence an organo-aluminum catalyst at constant temperature, with separation and continuous removal of CO2 and alcohol formed. Preparation of unsaturated ketones of formula (I) by reaction of the corresponding alpha , beta -unsaturated alcohol of formula (II) with an alkyl acetoacetate compound of formula (III) in the presence of 0.1-5 mole% (based on (III)) of an organo-aluminum catalyst with separation and continuous distillative removal of CO2 and alcohol of formula R3OH formed during reaction, in a reactor containing a fractionation column, where: (A) (II) is added to the reaction mixture together with the organic catalyst without additional solvent and (III) is then added to this mixture; (B) the reaction temperature is kept constant between 175-220 degrees C; (C) the content of (III) is kept at a constant level between 0.1-10 wt.% during the reaction. R1, R3 = 1-4C alkyl; R2 = 4-30C aliphatic, cycloaliphatic or cycloaliphatic-aliphatic; a, b = optional additional bonds.

公开(公告)号：DE10050711A1

公开(公告)日：2002-04-25

申请号：DE10050711

申请日：2000-10-13

Applicant: BASF AG

Inventor： BOETTCHER ARND ,  OOST CARSTEN ,  HAAKE MATHIAS

IPC: C07B61/00 ,  C07C5/10 ,  C07C13/18 ,  C07C209/72 ,  C07C211/35 ,  C07B35/02 ,  C07C29/19 ,  B01J23/46

Abstract: Hydrogenation of a mono- or multi-nuclear aromatic, optionally substituted by an alkyl, amine and/or hydroxy group, to the corresponding cycloaliphatic with gaseous hydrogen in the presence of at least one catalyst in a reactor column comprises feeding the reactants over the fixed catalyst in the column such that the cycloaliphatic is removed via side take off and/or sump of column.